Clinical assessment of detection of ventricular extrasystoly in patients without structural changes of heart: a prospective study

Aim. The aim of the study was a clinical assessment of the integrated determination of predictors of life-threatening ventricular arrhythmias (LVA) in patients with ventricular extrasystole (VE) without structural changes in the heart to predict the development of cardiovascular disease in a prospective study. Material and methods. From 1997 to 2014 199 patients with neurocirculatory dystonia (NCD), complicated with VE II-V class EE at the age of 18-35 years (mean 27.3-2.6 years) were observed in District Military Clinical Hospital of the Ministry of Defense of the Russian Federation, City Hospital named after St. Martyr Elizabeth. All patients, in addition to a general clinical examination, determined late potentials of the ventricles (LPV), QT interval variability (QTd), heart rate turbulence (HRT), and also indicators reflecting the possible mechanism of VE development. Results. The results of the study showed that in patients with NCD complicated by VE, the detection of indicators reflecting the presence of VE caused by the mechanisms of early post-depolarization and re-entry is a predictor of the development of coronary heart disease (CHD) and hypertension (HB). The positive prognostic significance of the indicators showing the presence of VE with these development mechanisms for the development of CHD and HB averaged 74% and 44% respectively, and with the appointment of сlass III drugs for elimination of VE and (or) development of unstable ventricular tachycardia, the risk of developing CHD increased to an average of 93%. Identification of NDC patients with indicators reflecting the presence of VE due to delayed post-depolarization is a predictor of the development of gastrointestinal tract (GT) diseases with positive prognostic significance, averaging 61%. Positive prognostic significance with respect to the development of CHD, HB, GT diseases for the detected LPV, QTd > 80 ms, pathological values of HRT VE did not exceed 30%. Indicators and predictors, which characterize the mechanism of development of VE and the risk of LVA occurrence in patients with NCD complicated by VE, were highly correlated (r > 0.50) with risk factors for cardiovascular and gastrointestinal system diseases.

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Preliminary clinical assessment of dynamic carbon-11 methionine positron-emission tomography/computed tomography for the diagnosis of the pathologies in patients with musculoskeletal lesions: a prospective study

European Journal of Hybrid Imaging ◽

10.1186/s41824-020-00083-x ◽

2020 ◽

Vol 4 (1) ◽

Author(s):

Takayoshi Shinya ◽

Yoichi Otomi ◽

Toshihiko Nishisho ◽

Bettina Beuthien-Baumann ◽

Michiko Kubo ◽

...

Keyword(s):

Computed Tomography ◽

Positron Emission Tomography ◽

Prospective Study ◽

Clinical Assessment ◽

Emission Tomography ◽

Positron Emission ◽

A Prospective Study ◽

Musculoskeletal Lesions

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Life-threatening adverse drug reactions at admission to medical intensive care: a prospective study in a teaching hospital

Intensive Care Medicine ◽

10.1007/s00134-007-0787-8 ◽

2007 ◽

Vol 33 (12) ◽

pp. 2150-2157 ◽

Cited By ~ 24

Author(s):

Marieke Grenouillet-Delacre ◽

Hélène Verdoux ◽

Nicholas Moore ◽

Françoise Haramburu ◽

Ghada Miremont-Salamé ◽

...

Keyword(s):

Intensive Care ◽

Prospective Study ◽

Adverse Drug Reactions ◽

Teaching Hospital ◽

Drug Reactions ◽

Life Threatening ◽

Medical Intensive Care ◽

A Prospective Study

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The value of IgG to IgM ratio in predicting secondary dengue infection

Paediatrica Indonesiana ◽

10.14238/pi46.3.2006.113-7 ◽

2016 ◽

Vol 46 (3) ◽

pp. 113 ◽

Cited By ~ 2

Author(s):

I Putu Gede Karyana ◽

Hendra Santoso ◽

Bagus Ngurah Putu Arhana

Keyword(s):

Prospective Study ◽

Hemagglutination Inhibition ◽

Good Predictor ◽

Primary Infection ◽

Secondary Infection ◽

Dengue Infection ◽

Diagnostic Value ◽

Post Test ◽

A Prospective Study

Background The determination of primary or secondary dengueinfection using hemagglutination inhibition (HI) test is time-con-suming. The IgG to IgM ratio which can be obtained earlier wasused by several studies to differentiate secondary from primaryinfection, but they still reported various cut-off points.Objective To find the diagnostic value and best cut off point ofIgG to IgM ratio for predicting secondary dengue infection.Methods This was a prospective study carried out between July2003 and June 2004. Children with suspected dengue hemor-rhagic fever (DHF) were tested for HI during acute and convales-cent phase. The IgG and IgM titer were examined during the acutephase using ELISA method.Results Sixty-two children were recruited, 48 with secondary in-fection and 14 with primary infection. The prevalence of second-ary infection was 77%. The best cut off point of the IgG to IgM ratioto predict secondary infection was >1.1 with sensitivity of 87.5%,specificity 92.9%, likelihood ratio 12.3, and post test probability97.7%.Conclusion The IgG to IgM ratio of >1.1 is a good predictor forsecondary infection

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