scholarly journals SOME ASPECTS OF THE PATHOGENESIS OF ISCHEMIC-HYPOXIC LESIONS OF THE CENTRAL NERVOUS SYSTEM IN NEWBORNS

2015 ◽  
Vol 4 (2) ◽  
pp. 112-115
Author(s):  
Lyudmila Viktorovna Ledyaikina ◽  
Larisa Alexandrovna Balykova ◽  
Svetlana Vasilyevna Garina ◽  
Olga Nikolaevna Soldatova ◽  
A A Tolkunova ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Lipid Metabolism ◽  
Red Blood Cells ◽  
Brain Damage ◽  
Blood Cells ◽  
Phospholipid Bilayer ◽  
Care Practice ◽  
Perinatal Morbidity ◽  
The Central Nervous System

The problem of perinatal morbidity in case of insufficiently high fertility in Russia is one of the most relevant at the monent. The leading cause of perinatal morbidity and mortality continue to remain hypoxic-ischemic brain damage the fetus and newborn. Ischemic-hypoxic damage of the central nervous system (CNS) is the most dangerous and prognostic significance. They often fatal and takes a leading role in the future of children and maladjustment of severe disabling diseases. Introduction of innovative medical technologies in health care practice greatly enhances the study of the causes of many diseases and abnormalities in newborns and helps to clarify the etiology, pathogenetic mechanisms, clinical and morphological structure, as well as typical for different gestational age localization of brain damage. It is shown that the generalized disorder of lipid metabolism with the development membranodestruktive processes is closely correlated with the severity of hypoxic-ischemic lesions of the central nervous system. It was found that infants who underwent antenatal and / or intranatal hypoxia, there are significant transformation of lipid metabolism lead to changes in the composition of lipids of blood plasma and red blood cells (with the accumulation level of chaotropic fractions phospholipid bilayer membranes of red blood cells - Lizoform phospholipids and free fatty acids). The necessity inclusion complex therapy consequences of perinatal hypoxia drugs, which have antioxidant, antihypoxic activity and the ability to regulate lipid metabolism.

Bleeding after salvarsan

1927 ◽  
Vol 23 (11) ◽  
pp. 1183-1183
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Side Effects ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Adverse Side Effects ◽  
The Central Nervous System ◽  
Capillary Walls

The adverse side effects of salvarsan injections include bleeding from the nose, gums, kidney, lung, etc. The reason for this is the permeability of the capillary walls to red blood cells due to irritation of the central nervous system in persons who are too sensitive to salvarsan. They are caused by the permeability of the capillary walls to red blood cells, caused by irritation of the central nervous system in persons over-sensitive to salvarsan.

scholarly journals MALFORMATION OF THE ERYTHROCYTES IN A CASE OF ATYPICAL RETINITIS PIGMENTOSA

Blood ◽  
1950 ◽  
Vol 5 (4) ◽  
pp. 381-387 ◽  
Author(s):  
FRANK A. BASSEN ◽  
ABRAHAM L. KORNZWEIG
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Retinitis Pigmentosa ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Neurologic Examination ◽  
Diffuse Disease ◽  
The Central Nervous System ◽  
One Year ◽  
Hereditary Nature

Abstract A case is presented of a girl, aged 18, born of parents who were first cousins. She had an atypical retinitis pigmentosa with involvement of the macula. The neurologic examination showed diffuse disease of the central nervous system, as seen in Friedreich’s ataxia. An additional finding (hitherto undescribed) was that of a malformation of the red blood cells. These cells had a peculiar crenated appearance, due to the presence of pseudopods or protoplasmic projections varying in size and shape. They were constantly present in stained blood films taken one year apart. A similar finding in a younger brother, with beginning retinal pigmentary degeneration, added additional proof of the hereditary nature of the condition.

scholarly journals METHOD FOR PREDICTING PERINATAL HYPOXIC LESIONS OF THE CENTRAL NERVOUS SYSTEM IN NEWBORNS

2019 ◽  
Vol 64 (2) ◽  
pp. 89-93 ◽  
Author(s):  
A. . Smirnova ◽  
N. . Borzova ◽  
N. . Sotnikova ◽  
A. . Malyshkina ◽  
E. . Bojko
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Pregnant Women ◽  
Preterm Labor ◽  
Venous Blood ◽  
Perinatal Morbidity ◽  
The Central Nervous System

Perinatal lesions of the Central nervous system (CNS) in newborns occupy a leading place in the structure of perinatal morbidity and subsequent disability of children. To identify the features of the content of sRAGE in pregnant women with threatening preterm labor (UPR) in the period of 22-27 weeks, who subsequently gave birth to children with perinatal CNS lesion. Serum of venous blood of pregnant women with UPR at the term of 22-27 weeks was determined by ELISA once the content of sRAGE. If the value of sRAGE in pregnant women is 659.5 PG/ml or less, perinatal hypoxic lesions of the Central nervous system in newborns are predicted with an accuracy of 75.8% (sensitivity of 82.6%, specificity of 66.7%).

Central nervous system-directed neuronotrophic activity present in red blood cells

1985 ◽  
Vol 336 (1) ◽  
pp. 99-105 ◽  
Author(s):  
Lawrence R. Williams ◽  
Ivan Selak ◽  
Stephen D. Skaper ◽  
Marston Manthorpe ◽  
Silvio Varon
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Red Blood Cells ◽  
Blood Cells

Brain Injury Associated With Chronic Alcoholism

CNS Spectrums ◽  
1999 ◽  
Vol 4 (1) ◽  
pp. 66-68,81-87 ◽  
Author(s):  
Paul W. Ragan ◽  
Charles K. Singleton ◽  
Peter R. Martin
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Brain Injury ◽  
Alcohol Abuse ◽  
Brain Damage ◽  
Thiamine Deficiency ◽  
Chronic Alcoholism ◽  
Cerebellar Degeneration ◽  
Wernicke's Encephalopathy ◽  
The Central Nervous System

AbstractAlcoholism can result in a number of severe consequences to the central nervous system, including Korsakoff's psychosis, delusions, delirium, Wernicke's encephalopathy, and cerebellar degeneration. Many of these disorders have a substantially higher prevalence than had been previously believed. Neuropathologic and neuroimaging studies have been instrumental in identifying the changes undergone by the alcoholic brain and the factors that may contribute to alcohol-induced brain damage. Biologic differences appear to make women especially susceptible to central nervous system insult from alcohol abuse. The damage caused by alcohol may be associated, in part, with thiamine deficiency, neuronal excitotoxicity, and magnesium wasting.

Changes in Porteus Maze Scores of Brain-Operated Schizophrenics After an Eight-Year Interval

1960 ◽  
Vol 106 (444) ◽  
pp. 967-978 ◽  
Author(s):  
Aaron Smith
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Brain Damage ◽  
Brain Function ◽  
Special Importance ◽  
Cortical Lesions ◽  
Additional Source ◽  
Adequate Knowledge ◽  
The Central Nervous System ◽  
Subjective Estimates

The voluminous literature reporting the effects of cortical lesions has shown contradictory and diverse findings from the earliest studies to the present (Franz, 1907; Klebanoff, 1945; Klebanoff, Singer and Wilensky, 1954; Meyer, 1957). Some investigators found no losses in intellectual function regardless of the locus of the lesion; others, a temporary loss followed by recovery of original capacity. Still others have reported significant losses following brain damage in the forebrain or other portions of the central nervous system. But for investigators in all three categories, what did “brain damage” consist of? The neurologists Brain and Strauss have observed “The study of psychological problems without an adequate knowledge of the physiology and pathology of the central nervous system can be likened to the exploration of the uncharted seas without the aid of a compass; and yet there are many psychologists who undertake the rash venture” (1955, p. vi). And what of the criteria on which the conclusions were based? An additional source of ambiguity is indicated by the fact that the overwhelming majority of conclusions on “mental” changes by psychiatrists and neurologists have generally been based on clinical or subjective estimates.Measurement, a crucial factor in any study, is of special importance in studies of brain damage and brain function, although despite a multiplicity of tests, there are few measures designed with attention to their unique problems. Tests employed in many psychological studies of brain damage were originally oriented toward quite different problems and had been carefully developed and standardized on non-brain damaged populations.

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