scholarly journals Ways to optimize the assessment of lean body mass in hemodialysis patients

2019 ◽  
Vol 9 (1) ◽  
pp. 23-28
Author(s):  
Juliia V. Lavrishcheva ◽  
Aleksandr A. Jakovenko

The aim. To conduct a comparative analysis of the effectiveness of methods for assessing lean body mass in haemodialysis patients. Patients and methods. A total of 317 patients receiving treatment with programmatic bicarbonate haemodialysis in 9 haemodialysis centers in 5 regions of the European part of the Russian Federation were examined for 8.2 ± 5.1 years, among them 171 women and 146 men, the average age was 57.1 ± 11.3 years. Dual-energy X-ray absorptiometry and bioimpedancemetry were used to assess lean body mass. Results. The results of determining the total lean body mass obtained from the results of dual-energy X-ray absorptiometry and bioimpedancemetry were compared using the Bland-Altman method. The correlation coefficient between the indicators was r = 0.994, p < 0.0001, delta (M ± σ) was –0.48 ± 0.91 kg, CI 95% (–0.71)–(–0.26) kg. Conclusion. Dual-energy X-ray absorptiometry has no significant advantages compared with bioimpedancemetry when evaluating lean body mass in haemodialysis patients.

Author(s):  
A. A. Jakovenko ◽  
O. Y. Shestopalova ◽  
A. Sh. Rumyantsev ◽  
V. M. Somova

The aim of the study. Compare the efficiency of the use of dual-energy x-ray absorptiometry (DRA) and bioimpedansometry (BIM) in the evaluation of the body composition of hemodialysis patients.Patients and methods. 67 patients on hemodialysis, among which 23 men and 44 women aged 54±14,4 years. BIM and DRA were used to evaluate the body composition.Results. The results of determining the total muscle mass of the body obtained by the results of DFA and BIM were compared with the use of the Bland-Altman method. The correlation coefficient between the indices was R=0,994, p<0,0001, delta (M±s) was –0,48±0,91 kg, CI 95% (–0,71)…(–0,26) kg.Conclusion. DRA does not have significant advantages over tetrapolar multifrequency BIM when assessing the body composition in hemodialysis patients. 


Toxins ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 278
Author(s):  
Dongwoo Lee ◽  
Jaewon Kim ◽  
Ja-Young Oh ◽  
Mi-Hyang Han ◽  
Da-Ye Kim ◽  
...  

We aimed to evaluate muscle mass changes after injection of botulinum toxin (BoNT) in children with spastic hemiplegic cerebral palsy (CP). Children aged between 2 and 12 years who were diagnosed with hemiplegic CP with spastic equinus foot were prospectively recruited and administered BoNT in the affected leg. Lean body mass (LBM) of both legs and total limbs was measured by dual-energy X-ray absorptiometry (DXA) preinjection and 4 and 12 weeks after injection. A total of 15 children were enrolled into the study. LBM of both legs and total limbs increased significantly over 12 weeks of growth. The ratio of LBM of the affected leg to total limbs and to the unaffected leg significantly reduced at 4 weeks after injection compared with preinjection but significantly increased at 12 weeks after injection compared with 4 weeks after injection. In conclusion, the muscle mass of the affected leg after BoNT injection in children with hemiplegic spastic CP decreased at 4 weeks after BoNT injection but significantly recovered after 12 weeks after injection.


2011 ◽  
Vol 106 (S1) ◽  
pp. S57-S59 ◽  
Author(s):  
Kathryn E. Michel ◽  
Wendy Anderson ◽  
Carolyn Cupp ◽  
Dorothy P. Laflamme

Body condition scoring (BCS) systems primarily assess body fat. Both overweight and underweight animals may have loss of lean tissue that may not be noted using standard BCS systems. Catabolism of lean tissue can occur rapidly, may account for a disproportionate amount of body mass loss in sick cats and can have deleterious consequences for outcome. Therefore, along with evaluation of body fat, patients should undergo evaluation of muscle mass. The aims of the present study were first to evaluate the repeatability and reproducibility of a 4-point feline muscle mass scoring (MMS) system and second to assess the convergent validity of MMS by dual-energy X-ray absorptiometry (DXA). MMS was as follows: 3, normal muscle mass; 2, slight wasting; 1, moderate wasting; 0, severe wasting. For the first aim, forty-four cats were selected for evaluation based on age and BCS, and for the second aim, thirty-three cats were selected based on age, BCS and MMS. Cats were scored by ten different evaluators on three separate occasions. Body composition was determined by DXA. Inter- and intra-rater agreement were assessed using kappa analysis. Correlation between MMS and BCS, age, percentage lean body mass and lean body mass (LBM) was determined using Spearman's rank-order correlation. The MMS showed moderate inter-rater agreement in cats that scored normal or severely wasted (κ = 0·48–0·53). Intra-rater agreement was substantial (κ = 0·71–0·73). The MMS was significantly correlated with BCS (r 0·76, P < 0·0001), age (r − 0·75, P < 0·0001), LBM (g) (r 0·62, P < 0·0001) and percentage LBM (r − 0·49, P < 0·0035). Additional investigation is needed to determine whether the MMS can be refined and to assess its clinical applicability.


2018 ◽  
Vol 37 ◽  
pp. S223-S224
Author(s):  
J. Mareschal ◽  
M. Pruijm ◽  
D. Teta ◽  
C. Stoermann ◽  
N. Marangon ◽  
...  

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