scholarly journals IR and 1H NMR Spectral Studies of some 2-Amino-4-Isopropyl-6-Methoxy-N-Phenylpyrimidine-5-Carboxamides: Assessment of Substituent Effects

2014 ◽  
Vol 38 ◽  
pp. 15-25 ◽  
Author(s):  
R. Arulkumaran ◽  
R. Sundararajan ◽  
V. Manikandan ◽  
V. Sathiyendiran ◽  
S. Pazhamalai ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Spectral Data ◽  
Linear Regression Analysis ◽  
Substituent Effects ◽  
Spectral Studies ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
H Nmr ◽  
Multi Linear Regression ◽  
Spectral Group

A series of 2-Amino-4-isopropyl-6-methoxy-N-phenylpyrimidine-5-carboxamide compounds have been synthesized from various substituted dithioacetal and guanidine. The purities of these compounds were checked by their physical constants, UV, IR, NMR and MASS spectral data. The IR and 1HNMR spectral data of these compounds have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effects of substituents on the spectral group frequencies have been discussed.

scholarly journals Assessment of Substituent Effects and Antimicrobial Activities of some 2ʹ,5ʹ-Dimethyl Phenyl Chalcones

2013 ◽  
Vol 24 ◽  
pp. 99-123
Author(s):  
S. John Joseph ◽  
D. Kamalakkannan ◽  
R. Arulkumaran ◽  
S.P. Sakthinathan ◽  
R. Suresh ◽  
...  
Keyword(s):  
Spectral Data ◽  
Aldol Condensation ◽  
Linear Regression Analysis ◽  
Substituent Effects ◽  
Catalytic Amount ◽  
Antimicrobial Activities ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Multi Linear Regression ◽  
Spectral Group

Some 2ʹ,5ʹ-dimethyl phenyl chalcones have been synthesized by Crossed-Aldol condensation between 2,5-dimethyl acetophenone and various substituted benzaldehydes using catalytic amount of sodium hydroxide and ethanol. The yields of the chalcones are more than 93%. The purities of these chalcones have been checked by their physical constants, UV, IR, NMR and MASS spectral data. The spectral data of these chalcones have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effects of substituents on the spectral group frequencies have been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby method

scholarly journals Spectral Correlations and Antimicrobial Activities of some 1-Pyrenyl Chalcones

2013 ◽  
Vol 10 ◽  
pp. 21-38
Author(s):  
R. Arulkumaran ◽  
S. Vijayakumar ◽  
R. Sundararajan ◽  
S.P. Sakthinathan ◽  
D. Kamalakkannan ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Spectral Data ◽  
Aldol Condensation ◽  
Linear Regression Analysis ◽  
Antimicrobial Activities ◽  
Microbial Activities ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Multi Linear Regression ◽  
Spectral Group

A series of 1-pyrenyl chalcones have been synthesized by Crossed-Aldol condensation of 1-acetylpyrene and substituted benzaldehydes. The purities of these chalcones have been checked by their physical constants, UV, IR, NMR and MASS spectral data. The spectral data of these chalcones have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effect of substituents on the spectral group frequencies have been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby method.

scholarly journals Infrared and 13C NMR Spectral Studies of some Aryl Hydrazides: Assessment of Substituent Effects

2014 ◽  
Vol 32 ◽  
pp. 88-94 ◽  
Author(s):  
Ganesamoorthy Thirunarayanan ◽  
K.G. Sekar ◽  
R. Lakshmi Narayanan
Keyword(s):  
Regression Analysis ◽  
Statistical Analysis ◽  
Linear Regression ◽  
Linear Regression Analysis ◽  
Substituent Effects ◽  
Spectral Studies ◽  
Substituent Constants ◽  
Multi Linear Regression ◽  
Spectral Group ◽  
C Nmr

A series of some aryl hydrazides have been synthesized. These hydrazides purities were analyzed by physical constants and spectral data. The assigned spectral group frequencies were correlated with Hammett substituent constants and Swain-Lupton parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effect of substituents on the spectral group frequencies has been discussed

scholarly journals Spectral Correlation Analysis and Antimicrobial Activities of some 2,4-Dimethoxy Phenyl Chalcones

2013 ◽  
Vol 23 ◽  
pp. 48-65
Author(s):  
S. John Joseph ◽  
R. Arulkumaran ◽  
D. Kamalakkannan ◽  
S.P. Sakthinathan ◽  
R. Sundararajan ◽  
...  
Keyword(s):  
Spectral Data ◽  
Aldol Condensation ◽  
Linear Regression Analysis ◽  
Antimicrobial Activities ◽  
Microbial Activities ◽  
Mass Spectral Data ◽  
Spectral Correlation ◽  
Mass Spectral ◽  
Multi Linear Regression ◽  
Spectral Group

A series of 2,4-dimethoxy phenyl chalcones have been synthesized by Crossed-Aldol condensation of 2,4-dimethoxy phenyl and various substituted benzaldehydes. The purities of these chalcones have been checked by their physical constants, UV, IR, NMR and MASS spectral data. The spectral data of these chalcones have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effects of substituents on the spectral group frequencies have been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby method.

scholarly journals Spectral Correlations in some Substituted Styryl (E)-4-((2-Oxopropyl)Diazenyl) Benzoic Acids

2014 ◽  
Vol 30 ◽  
pp. 33-43
Author(s):  
V. Sathiyendiran ◽  
K.G. Sekar ◽  
Ganesamoorthy Thirunarayanan ◽  
R. Arulkumaran ◽  
R. Sundararajan ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Statistical Analysis ◽  
Linear Regression ◽  
Linear Regression Analysis ◽  
Benzoic Acids ◽  
Effect Of Substituents ◽  
Substituent Constants ◽  
Multi Linear Regression ◽  
Spectral Group

A series of titled compounds were prepared and analyzed their purities by literature method. The infrared and NMR spectral group frequencies of the compounds were assigned and correlated with Hammett substituent constants, F and R constants using single and multi linear regression analysis. From the results of statistical analysis, the effect of substituents on the above spectral frequencies was discussed.

scholarly journals Synthesis and Antimicrobial Activity ofSome New 2-Substituted Benzothiazole Derivatives

2009 ◽  
Vol 6 (3) ◽  
pp. 775-779 ◽  
Author(s):  
B. Rajeeva ◽  
N. Srinivasulu ◽  
S. M. Shantakumar
Keyword(s):  
Antimicrobial Activity ◽  
Spectral Data ◽  
Diffusion Method ◽  
Disc Diffusion ◽  
Phosphoryl Chloride ◽  
Mass Spectral Data ◽  
Disc Diffusion Method ◽  
Mass Spectral ◽  
Benzothiazole Derivatives ◽  
H Nmr

Some new 2-(5-substituted-1,3,4-oxadiazole-2-yl)-1,3- benzothiazole(3a-j)were synthesized by refluxing benzothiazolyl carboxyhydrazide with different aryl acids in phosphoryl chloride. Structures of the synthesized compounds were established on the basis of1H NMR and Mass spectral data. The anti microbial activity of the synthesized compounds was evaluated by disc diffusion method.

Synthesis, spectroscopic and electrochemical investigations of supramolecular nickel(II)tetraazaporphyrin complexes

2005 ◽  
Vol 09 (07) ◽  
pp. 509-518 ◽  
Author(s):  
Rajendra Prasad ◽  
Ajay Kumar
Keyword(s):  
Cyclic Voltammetry ◽  
Spectral Data ◽  
Electronic Absorption ◽  
Electronic Interaction ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
H Nmr ◽  
High Degree

The ( bpy )2 Ru II and ( phen )2 Ru II moieties were linked to [ Ni ( OBTTAP )]1, periphery through coordinate bonds in order to synthesize cationic di- and pentanuclear complexes 2-5 that were obtained as PF 6− salts. They were characterized by IR, 1 H NMR, UV-vis, and mass spectral data. The electronic absorption, emission and redox data of these bichromophoric systems indicate the presence of a high degree of intercomponent electronic interaction. The position and relative intensities of the Soret and Q bands in these complexes is altered due to peripheral binding of the metal units. The compounds were non-emissive for the Q band excitation but, Soret excitation led to a strong S 2 emission, observed between 400-450 nm. In cyclic voltammetry, the compounds exhibited one Ru centered oxidation together with one or two OBTTAP centered oxidations. The Ru II/ Ru III oxidations were observed at significantly lower potentials as compared to the corresponding simple maleonitrile-benzylthioether complexes and has been interpretted in terms of weaker d π( S )– d π( Ru ) interactions.

scholarly journals Preheated Fly-Ash Catalyzed Cyclization of Chalcones: Synthesis of some Substituted Pyrazole-1-Carbothioamides and Spectral Correlations in 3-(3,4-Dichlorophenyl)-5-(Substituted Phenyl)-4,5-Dihydro-1H-Pyrazole-1-Carbothioamides

2013 ◽  
Vol 15 ◽  
pp. 18-34 ◽  
Author(s):  
Ganesamoorthy Thirunarayanan ◽  
K.G. Sekar
Keyword(s):  
Regression Analysis ◽  
Fly Ash ◽  
Linear Regression ◽  
Microwave Irradiation ◽  
Spectral Data ◽  
Linear Regression Analysis ◽  
Solvent Free ◽  
Physical Constants ◽  
Multi Linear Regression ◽  
Substituted 1

Some substituted 1-thiocarbomyl pyrazolines including 3-(3,4-dichlorophenyl)-5-(substituted phenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamides using solvent-free preheated fly-ash catalyzed cyclization between chalcones and thiosemicarbazide microwave irradiation. The yields of these thiocarbomyl pyrazolines are more than 80%. The purities of these synthesised pyrazoline derivatives are checked by their physical constants and spectral data earlier reported in the literature. The spectral data of these 3-(3,4-dichlorophenyl)-5-(substituted phenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamides had been correlated, using single and multi-linear regression analysis.

scholarly journals Synthesis and Antimicrobial Activity of (2-Methoxy/2-Amino)-6-{4'-[(4'''-Chlorophenyl) (Phenyl) Methyl Amino] Phenyl}-4-Aryl Nicotinonitrile

2015 ◽  
Vol 49 ◽  
pp. 99-103
Author(s):  
J.V. Guna ◽  
V.N. Bhadani ◽  
H.D. Purohit ◽  
Dipak M. Purohit
Keyword(s):  
Antimicrobial Activity ◽  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Spectral Data ◽  
Elemental Analysis ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
H Nmr ◽  
Bacteria And Fungi ◽  
Layer Chromatography

2- Methoxy – 6 - {4' - [(4'''- Chlorophenyl) (phenyl) methyl amino] phenyl} - 4 - aryl nicotinonitrile (3a-3l) and 2-Amino-6-{4'-[(4'''-Chlorophenyl)(phenyl)methyl amino]phenyl}-4-aryl nicotinonitrile (4a-4l) have been synthesized. The products have been assayed for their antimicrobial activity against Gram +ve, Gram -ve bacteria and fungi. The structure of the products has been elucidated by IR, 1H-NMR, mass spectral data, elemental analysis and thin layer chromatography.

Cyclopropanes of 5-nitrofuran series

1979 ◽  
Vol 44 (2) ◽  
pp. 420-423 ◽  
Author(s):  
Josef Prousek ◽  
Adolf Jurášek ◽  
Miloslava Dandárová ◽  
Jaroslav Kováč
Keyword(s):  
Spectral Data ◽  
Reaction Products ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
H Nmr

5-Nitrofurfuryl trichloromethyl sulphone (I) was reacted with paraformaldehyde in methanol in the presence of piperidine as catalyst to give 1-(5-nitro-2-furyl)-1-trichloromethylsulphonyl-2-(5-nitro-2-furyl)cyclopropane. This substance was also obtained from 1-(5-nitro-2-furyl)-1-trichloromethylsulphonyl-2-(5-nitro-2-furyl)ethylene and diazomethane. The reaction products were characterized by IR, UV, 1H NMR and mass spectral data.

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