scholarly journals Digital biomanufacturing supporting vascularization in 3D bioprinting

Author(s):  
William Whitford ◽  
James B. Hoying

 Synergies in bioprinting are appearing from individual researchers focusing on divergent aspects of the technology. Many are now evolving from simple mono-dimensional operations to model-controlled multi-material, interpenetrating networks using multi-modal deposition techniques. Bioinks are being designed to address numerous critical process parameters. Both the cellular constructs and architectural design for the necessary vascular component in digitally biomanufactured tissue constructs is being addressed. Advances are occurring from the topology of the circuits to the source of the of the biological microvessel components. Instruments monitoring and control of these activates are becoming interconnected. More and higher quality data are being collected and analysis is becoming richer. Information management and model generation is now describing a “process network.” This is promising; more efficient use of both locally and imported raw data supporting accelerated strategic as well as tactical decision making. This allows real time optimization of the immediate bioprinting bioprocess based on such high value criteria as instantaneous progress assessment and comparison to previous activities. Finally, operations up- and down-stream of the deposition are being included in a supervisory enterprise control.

2020 ◽  
Vol 166 ◽  
pp. 01002
Author(s):  
Оlena Pomortseva ◽  
Sergiy Kobzan ◽  
Andrey Yevdokimov ◽  
Maksym Kukhar

The purpose of the study, the materials of which are outlined in this article, is to uncover current trends in the development of environmental monitoring and the tracking of anthropogenic environmental impacts. To achieve this goal, it is proposed to use geoinformation systems to perform environmental monitoring and control, using appropriate software. For this purpose ArcGis software was used which allows monitoring the state of the atmosphere, its pollution and other deviations from the norm. The research was conducted exemplified by nine districts of Kharkiv. As a result of computer geospatial analysis, models and maps of urban pollution have been developed. In general, the intellectual analysis of geostatic models of emission distribution in the city allowed identifying and classifying zones of high concentrations of pollution and comparing them with air quality data. Methods of geostatistics transformed the data from a discrete to a continuous form of representation. Further studies in this area may be related to the improvement of geostatistical data analysis and pollution distribution prediction methods. As an example, mathematical formulas were presented to determine the atmospheric pollution index and the true or predicted pollution index, which can be determined on the basis of the data obtained and represented by elements of the ArcGis software package in a discrete and continuous form.


2020 ◽  
Vol 35 (1) ◽  
pp. 51-67
Author(s):  
A.S.A. Al-Masri ◽  

RN-659 cars are essential to ensure high reliability and stability of the international computer communication system. This case looks at the RNA C659 Series ray tracing model and debris failure mechanism. According to the pilot, a computer anti-aircraft system consisting of 4 aircraft was created. In addition, a computer and computer development program were created for the computer's command and screen components. Computer Security Management System does not complete invalid cards, computer votes, and sub-monitoring and control instructions.


Author(s):  
David C. Joy

Personal computers (PCs) are a powerful resource in the EM Laboratory, both as a means of automating the monitoring and control of microscopes, and as a tool for quantifying the interpretation of data. Not only is a PC more versatile than a piece of dedicated data logging equipment, but it is also substantially cheaper. In this tutorial the practical principles of using a PC for these types of activities will be discussed.The PC can form the basis of a system to measure, display, record and store the many parameters which characterize the operational conditions of the EM. In this mode it is operating as a data logger. The necessary first step is to find a suitable source from which to measure each of the items of interest. It is usually possible to do this without having to make permanent corrections or modifications to the EM.


2016 ◽  
Author(s):  
Giacomo Giannoccaro ◽  
Armando Ursitti ◽  
Maurizio Prosperi

2020 ◽  
pp. 4-10
Author(s):  
VLADIMIR V. KIRSANOV ◽  
◽  
DMITRIY YU. PAVKIN ◽  
FEDOR E. FEDOR E. VLADIMIROV ◽  
EVGENIY А. NIKITIN ◽  
...  

A modern dairy farm is a complex biotechnical “man-machine-animal” system, where purposeful human activity concentrates mainly on the control of the “machine” and “animal” subsystems, thus making the whole system ergatic. Increasing the interaction effi ciency of machine subsystems with biological objects (animals) requires an in-depth study of the properties and characteristics of the latter, their behavior, adaptive and refl ex mechanisms that ensure the mutual adaptation of machine and biological subsystems. The paper considers general functionality of the “animal” subsystem, which includes lists of monitored parameters (functions) in pre-weaning, pre-lactation and lactation periods. In a similar way, functionals of the subsystems of the general musculoskeletal development of the animal’s body, respiratory and digestive organs, comfort of the habitat, development and control of the reproductive organs of lactating cows were obtained accompanied with a list of controlled functions and parameters. To carry out a set of research activities in this fi eld, FSAC VIM is planning to carry out a complex project that will increase the levels of automation, digitalization and intellectualization of animal husbandry, provide for comfortable environment, optimal rediced-impact service modes for animals and their extended productive longevity, increased quality of milk and autonomous functioning of individual local biotechnical subsystems.


Author(s):  
Oleksandra Maslii ◽  
Andrii Maksymenko ◽  
Svitlana Onyshchenko

Place of monitoring and control of risks of financial stability of the state in the system of ensuring financial security of the state was substantiated. Methods of identifying threats to Ukraine's financial security through the current and strategic analysis of financial system development indicators were considered. Tendencies of economic development of Ukraine in the context of revealing sources of threats to financial stability of the state were analyzed. Dynamic analysis of the actual values of the financial security indicators of Ukraine as a whole and its separate components had been carried out. Threats to Ukraine's financial security were identified based on comparative and trend analysis. Reasons for the critical state of debt, banking and monetary security in the financial structure and the preconditions for the emergence of systemic threats had been investigated. Systematization of risks and threats to Ukraine's financial security by its components had been carried out. Influence of systemic threats in the financial sphere on the economic security of the state was generalized. International experience of monitoring financial stability of the state was analyzed. Additional risks to the national financial system are associated with the globalization and digitization of the state financial system that are not taken into account by valid methodological recommendations for calculating the level of economic security of Ukraine were highlighted.


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