scholarly journals A cross sectional knowledge attitude practice study on therapeutic drug monitoring among health care professionals in a tertiary care hospital

2020 ◽  
Vol 9 (6) ◽  
pp. 879
Author(s):  
Poovizhi Bharathi Rajaduraivelpandian ◽  
Padmaja Udaykumar
Keyword(s):  
Health Care ◽  
Therapeutic Drug Monitoring ◽  
Drug Monitoring ◽  
Tertiary Care ◽  
Therapeutic Drug ◽  
Sample Type ◽  
Cross Sectional ◽  
Attitude And Practice ◽  
Knowledge Attitude And Practice ◽  
Pharmacological Basis

Background: Therapeutic drug monitoring (TDM) is used to optimize drug’s therapeutic effect. Aim of this study is to assess the knowledge, attitude and practice of TDM in health care professionals.Methods: This was a questionnaire-based cross-sectional study. Questionnaires were distributed to 610 nursing staff and 20 lab technicians. Questionnaires had queries on demography, knowledge, attitude and practice. Descriptive statistics and Pearson correlation were used to analyse the data.Results: Among nurses, 7% had good, 60.9% had   fair and 32.2% had poor knowledge of TDM. Among lab technicians 18.2% had good and 81.8% had fair knowledge on TDM. 79.3% of nurses and all lab technicians had favourable attitude towards TDM. Weak positive correlation is seen between knowledge and attitude among nurses. 15.9% of nurses have sent request for TDM on phenytoin, sodium valproate, carbamazepine, methotrexate, lithium, clozapine, risperidone, tigecycline, vancomycin, gentamicin, digoxin and amiodarone. 100% lab technicians have estimated levels of methotrexate and lithium drug sample during the last one year.Conclusions: Though knowledge on indication and pharmacological basis of TDM is lacking among participants, their knowledge on sample collection and sample type is good. They have a positive attitude towards TDM. Nurses have requested TDM for only 12 drugs. TDM of only two drugs was done by lab technicians. Future training should focus on pharmacological basis, selection of appropriate drug candidate and indication for TDM service. TDM service should be made available in all tertiary care institutions.

scholarly journals KNOWLEDGE, ATTITUDE & PRACTICE OF COVID-19 AMONG HEALTH CARE WORKERS OF TERTIARY CARE HOSPITAL IN SOUTHERN RAJASTHAN

2020 ◽  
pp. 200-202
Author(s):  
C.P. Sharma ◽  
Anum Fatima ◽  
Omprakash Mahawar ◽  
Pratap Bhan Kaushik
Keyword(s):  
Health Care ◽  
Health Care Workers ◽  
Professional Education ◽  
Good Practice ◽  
Tertiary Care ◽  
Care Hospital ◽  
Cross Sectional ◽  
Attitude And Practice ◽  
Care Workers ◽  
Knowledge Attitude And Practice

BACKGROUND: The COVID-19 pandemic is escalating at an alarming rate and currently best therapy lies in prevention. OBJECTIVE:This study aims to determine knowledge ,attitude and practice of health care workers towards COVID-19.METHODOLOGY:A cross sectional descriptive study undertaken at Dedicated Covid Hospital, MBGH Udaipur,Rajasthan from April 2020 to May 2020.The response of 190 participants who filled questionnaire was tabulated and analysed .RESULT :Majority had an average knowledge (49.7%),positive attitude (57.4%) and good practice(51.1%) which was further influenced by various factors studied. CONCLUSION :Health care workers still require professional education and teachings dedicated to improve knowledge and promote good attitude and practice in regards of COVID-19.

scholarly journals Knowledge, attitude and practice of post-natal exercises among post-natal women from a tertiary care centre, South India

2020 ◽  
Vol 9 (4) ◽  
pp. 1366
Author(s):  
Raja Sundaramurthy ◽  
Sasikala Kathiresan ◽  
Sriandaal Venkateshvaran ◽  
Surya Kannan
Keyword(s):  
Health Care ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Postnatal Period ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Adequate Knowledge ◽  
Attitude And Practice ◽  
Source Of Information ◽  
Knowledge Attitude And Practice

Background: Stressful puerperal period and its complications can be prevented by adequate care, proper diet and exercises. Though studies have indicated post-natal exercises (PNE) is helpful in reducing the effect of perineal muscle weakness, many women are unaware of its full benefits. This study is planned to know the knowledge, attitude and practice of PNE in post-natal mothers.Methods: Descriptive cross-sectional study was conducted in department of obstetrics and gynecology for 3 months (November 2019 to January 2020). 160 post-natal women were enrolled with convenient sampling. Structured questionnaire was used to collect socio-demographic and obstetric details, source of information, knowledge, attitude and practice of PNE.Results: A total 58.8% of this study participants revealed health care professions were the commonest source of information. More than half of them had adequate knowledge but still many were not aware of full benefits of PNE as only 3-5% aware of other benefits like prevention of urinary incontinence. 98.8% of the women’s felt PNE is essential and 62.5% felt household work hinder them doing. 92.5% said they will emphasize the importance of PNE to others. No significant correlation found between socio-demographic characters and knowledge, attitude and practice of PNE.Conclusions: Though most of the study population had adequate knowledge and positive attitude, household activities were the commonest barrier in doing PNE. Educating and creating awareness among family members is essential to improve the adherence. Continuing influence by health care workers during antenatal and postnatal period will be the key for improving adherence.

scholarly journals Inappropriate Vancomycin Therapeutic Drug Monitoring in Hospitalized Pediatric Patients Increases Pediatric Trauma and Hospital Costs

2012 ◽  
Vol 17 (2) ◽  
pp. 159-165 ◽  
Author(s):  
Manika Suryadevara ◽  
Kelly E. Steidl ◽  
Luke A. Probst ◽  
Jana Shaw
Keyword(s):  
Health Care ◽  
Therapeutic Drug Monitoring ◽  
Health Care Provider ◽  
Care Provider ◽  
Drug Monitoring ◽  
Hospital Cost ◽  
Pediatric Patients ◽  
Tertiary Care ◽  
Therapeutic Drug ◽  
Trough Concentrations

OBJECTIVES The objective of this study was to measure the appropriateness of vancomycin monitoring in a pediatric tertiary care center and to evaluate the effectiveness of two interventions, autonomous pharmacy therapeutic drug monitoring and health care provider education, in reducing avoidable pediatric patient trauma and hospital cost. METHODS A retrospective chart review evaluating vancomycin therapeutic drug monitoring (TDM) in pediatric inpatients was performed before and after the introduction of an autonomous pharmacy TDM program and health care provider (HCP) education. RESULTS Thirty-five patients were included in our study, prior to any intervention. Of these, 9% of patients had trough concentrations appropriately deferred. Of the total of 64 trough concentrations obtained, 94% were considered to be inappropriate. After the start of the autonomous pharmacy TDM program, of the 54 eligible patients (111 troughs), 9% had trough concentrations appropriately deferred, and 34% were inappropriate. In the 3-month period following the introduction of HCP education in combination with pharmacy TDM, we identified 27 eligible patients. Among those, 15% of the patients had trough concentrations appropriately deferred. Of the 43 trough concentrations obtained, only 9% were considered to be inappropriate. The combination of pharmacy TDM with HCP education decreased annualized hospital cost by 60%, from $13,080 to $5232. CONCLUSIONS Inappropriate vancomycin TDM occurs commonly in our institution, resulting in unnecessary hospital cost and patient trauma. The combination of pharmacy TDM and HCP education significantly improved clinical practice; however, results were short-lived. Further interventions, such as computer based order entry, will likely be needed to reinforce and improve long-term TDM practice in pediatric patients.

scholarly journals Evaluation of the knowledge of Health Care Professionals regarding Therapeutic Drug Monitoring in Public Hospitals of Lahore, Pakistan

2020 ◽  
Vol V (I) ◽  
pp. 9-16
Author(s):  
Anam Arshad ◽  
Malik Irfan Zulfiqar ◽  
Zahra Hassan Kiani ◽  
Maria Hassan Kiani ◽  
Muhammad Rauf ul Hassan
Keyword(s):  
Health Care ◽  
Therapeutic Drug Monitoring ◽  
Drug Monitoring ◽  
Health Care Professionals ◽  
Medical Science ◽  
Cross Sectional Study ◽  
Public Hospitals ◽  
Therapeutic Drug ◽  
Cross Sectional ◽  
Developed Country

A cross sectional study was performed among 250 health care professionals from Children Hospital, Jinnah hospital and Services Institute of Medical science Lahore, through a self-designed questionnaire to assess the knowledge of therapeutic drug monitoring (TDM). A total 300 questionnaires were distributed and 250 were returned, giving a response 83%. Out of 300 health care professionals 50 participants do not even know the term TDM. Only 40% participants strongly agreed that TDM is done for all patients. Only 26.8% participants agreed that TDM is carried out for all drugs. Only 63.2% participants agreed that the TDM is very costly process. Only 38.4% strongly agreed that TDM requires extra time of health care professionals and only 36% participants remain neutral to the perception that TDM is requested by patient rather than health care professionals. Limited resources and lack of technical skills are barriers in performing TDM in under-developed country like Pakistan.

scholarly journals A questionnaire based cross sectional study of the knowledge, attitude and practice of pharmacovigilance among the health care professionals in a tertiary care teaching hospital in upper Assam, India

2019 ◽  
Vol 7 (10) ◽  
pp. 3833
Author(s):  
Swapnanil Gohain ◽  
Sahid Aziz ◽  
Meghali Chaliha
Keyword(s):  
Health Care ◽  
Health Care Professionals ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Adr Reporting ◽  
Attitude And Practice ◽  
Postgraduate Trainee ◽  
Knowledge Attitude And Practice

Background: Adverse drug reactions (ADR) are one of the major reason of morbidity, mortality and increase in health-care costs. The pharmacovigilance programme of India (PvPI) encourages the active participation of all health care professionals (HCP) in reporting suspected ADR to ensure enhanced patient safety. But present statistics shows under reporting of suspected ADR. So, this study was undertaken with the objectives of assessing knowledge, attitude and practice (KAP) of pharmacovigilance among the HCP and to evaluate various reasons of under reporting of suspected ADR.Methods: This is a cross-sectional observational study of knowledge, attitude and practice (KAP) of HCP including faculties, resident doctors and postgraduate trainee (PGT), internship doctors and nurses on pharmacovigilance; conducted at department of Pharmacology, Jorhat Medical College and Hospital(JMCH). The pretested and peer reviewed questionnaire was distributed among 150 HCP and the responses were collected after one day. Data were analyzed using MS-excel software and was expressed in percentage.Results: Out of 150 questionnaires, 118 responses were received (32 faculties, 27 PGT, 38 internship doctors and 21 nurses). Good knowledge (78.4%) and fair attitude was found among the HCP but there was lack of practice of pharmacovigilance due to reasons mainly non availability of suspected ADR reporting form (27.1%), didn’t think reporting was necessary (34%), fear of consequences (16.1%) and lack of awareness (16.1%) among others.Conclusions: Good attitude was observed among HCP. With proper measures like sensitization and educational intervention ADR, reporting may be improved in the future.

Therapeutic Drug Monitoring of Antiepileptic Drugs in a Tertiary Care Hospital in India

2015 ◽  
Vol 38 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Natarajan Harivenkatesh ◽  
Natarajan Haribalaji ◽  
Darling Chellathai David ◽  
C. M. Prabu Kumar
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Antiepileptic Drugs ◽  
Drug Monitoring ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Therapeutic Drug ◽  
Care Hospital

Patient-led Remote IntraCapillary pharmacoKinetic Sampling (fingerPRICKS) for therapeutic drug monitoring in patients with inflammatory bowel disease

2021 ◽  
Author(s):  
Desmond Chee ◽  
Rachel Nice ◽  
Ben Hamilton ◽  
Edward Jones ◽  
Sarah Hawkins ◽  
...  
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Drug Monitoring ◽  
Blood Sampling ◽  
Therapeutic Drug ◽  
Linear Regression Models ◽  
Cross Sectional ◽  
Immune Mediated ◽  
Low Volume ◽  
Antibody Levels ◽  
At Home

Abstract Background & Aims Because of COVID-19 public health restrictions, telemedicine has replaced conventional outpatient follow up for most patients with chronic immune-mediated inflammatory disorders treated with biologic drugs. Innovative solutions to facilitate remote therapeutic drug monitoring are therefore required. Low-volume intracapillary blood sampling can be undertaken by patients at home and samples returned by post to central laboratories. We sought to report the effect of the COVID-19 pandemic on requests for therapeutic drug monitoring and the equivalence, acceptability and effectiveness of low volume Patient-led Remote IntraCapillary pharmacoKinetic Sampling (fingerPRICKS) compared to conventional venepuncture. Methods We undertook a cross-sectional blood sampling methods comparison study and compared sample types using linear regression models. Drug and antidrug antibody levels were measured using standard ELISAs. Acceptability was assessed using a purpose-designed questionnaire. Results Therapeutic drug monitoring requests for adalimumab (96.5 [70.5 - 106] per week to 52 [33.5 - 57.0], p < 0.001) but not infliximab (184.5 [161.2 - 214.2] to 161 [135 – 197.5], p = 0.34) reduced during the first UK stay-at-home lockdown compared with the preceding six months. Fingerprick sampling was equivalent to conventional venepuncture for adalimumab, infliximab, vedolizumab, and ustekinumab drug, and anti-adalimumab and -infliximab antibody levels. The median (IQR) volume of serum obtained using intracapillary sampling was 195µL (130-210). More than 87% (90/103) patients agreed that intracapillary testing was easy and 69% (71/103) preferred it to conventional venepuncture. In routine care, 75.3% (58/77) patients returned two blood samples within 14 days to permit remote assessment of biologic therapeutic drug monitoring. Conclusions Therapeutic drug monitoring can be undertaken using patient-led remote intracapillary blood sampling and has the potential to be a key adjunct to telemedicine in patients with immune-mediated inflammatory diseases.

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