scholarly journals Cost variation analysis of different brands of oral anti-epileptic drugs available in India

2021 ◽  
Vol 10 (8) ◽  
pp. 948
Author(s):  
Nagavishnu Kandra ◽  
Rajesh B.
Keyword(s):  
Antiepileptic Drugs ◽  
Service Providers ◽  
Cost Effective ◽  
Muscular Contraction ◽  
Medical Care Cost ◽  
Cost Ratio ◽  
Price Variation ◽  
Medical Specialties ◽  
Cost Variation ◽  
Long Course

Background: Epilepsy is a group of neurological disorders, characterized by seizures, loss of consciousness, muscular contraction. Prevalence of epilepsy in India is about 1%. High medical care cost should be cause of concern for policy makers and service providers. Hence, a study was planned to analyse cost ratio and percentage cost variations of oral antiepileptic drugs available in India.Methods: An analytical study with maximum and minimum price of 10 tablets/capsules and syrup of one bottle of available strength of each drug was noted in Indian Rupee, using “Current Index of Medical Specialties” July to October 2020; “Drug Today” July To October 2020 volume-1 and “Indian Drug Review” 2020 volume-26 issue 6. Percentage cost variation and cost ratio for individual drugs was compared.Results: Significant cost variations were found in different brands of same drug. Among established oral antiepileptic drugs, Divalproex sodium 250 mg has highest cost ratio 16.071 and 1507.14% price variation and Clonazepam 0.25 mg with cost ratio 16.005 and 1500.55% price variation. Diazepam 2 mg has lowest cost ratio 1.024 and 2.43% price variation. Among newer oral antiepileptic drugs, Levetiracetam 500 mg has highest cost ratio 66.389 and 6538.93% price variation; least is Oxcarbazepine 450 mg with cost ratio 1.317 and 31.75% price variation.Conclusions: Epilepsy has long course of treatment. Increased adherence to treatment is achieved by switching to cost-effective therapy and by making Pharmacoeconomics an integral part of Undergraduate and Postgraduate Curriculum.

scholarly journals Cost variation analysis of commonly prescribed anti-diabetic drugs available in Indian market: a pharmaco-economic study

2021 ◽  
Vol 11 (1) ◽  
pp. 47
Author(s):  
Kajal S. Gupta ◽  
Milind L. Pardeshi ◽  
Rajesh S. Hiray
Keyword(s):  
Minimum Cost ◽  
Rapid Expansion ◽  
Fixed Dose ◽  
Cost Ratio ◽  
Pharmaceutical Pricing ◽  
Price Variation ◽  
Medical Specialties ◽  
Cost Variation ◽  
The Government ◽  
The Cost

Background: Diabetes mellitus (DM) is a chronic metabolic disorder requiring lifelong treatment. Due to rapid expansion of urbanization, unhealthy diet habits and sedentary lifestyle, the incidence of DM is increasing. The chronic nature of DM causes significant personal suffering and economic difficulty to families. The was aimed at investigating the cost difference in various brands of the same oral anti-diabetic drug.Methods: The minimum and the maximum cost in rupees (INR) of a particular anti-diabetic drug manufactured by various pharmaceutical companies were obtained from current index of medical specialties (CIMS) website, Indian drug review (IDR) 2021 issue and National pharmaceutical pricing authority-pharma sahi daam. The cost ratio and percentage cost variation were noted for each brand.Results: Amongst single drug therapy, metformin 500 mg sustained release showed highest price variation (3668%). Minimum cost variation was found with glipizide 2.5 mg (65%). Amongst the fixed dose combinations, highest cost variation was seen with glimepiride 2 mg+metformin 1000 mg (2703%) while minimum cost variation was found with repaglinide 1 mg+voglibose 0.3 mg (29%).Conclusions: A noticeable cost variation was found in different brands of the same anti-diabetic drug. Prescribing a more expensive brand when a cheaper one is available can burden the patient financially and thus reduce patient compliance. In addition, the Government should also include more anti-diabetic drugs under the price control policy to ensure that affordable and efficacious medicines are available to all.Background:  Diabetes mellitus (DM) is a chronic metabolic disorder requiring lifelong treatment. Due to rapid expansion of urbanization, unhealthy diet habits and sedentary life style, the incidence of DM is increasing .The chronic nature of DM causes significant personal suffering and economic difficulty to families. The present study aims at investigating the cost difference in various brands of the same oral anti-diabetic drug.Methods: The minimum and the maximum cost in rupees (INR) of a particular anti-diabetic drug manufactured by various brands were obtained from Current Index of Medical Specialties (CIMS) website, Indian Drug Review (IDR) 2021 issue and National Pharmaceutical Pricing Authority – Pharma sahi daam. The cost ratio and percentage cost variation were noted for each brand.Results: Amongst single drug therapy, Metformin 500mg Sustained Release showed highest price variation (3668%). Minimum cost variation was found with Glipizide 2.5mg (65%).Amongst the fixed dose combinations, highest cost variation was seen with Glimepiride 2mg + Metformin 1000mg (2703%) while minimum cost variation was found with Repaglinide 1mg + Voglibose 0.3mg (29%). Conclusions: A noticeable cost variation was found in different brands of the same anti-diabetic drug. Prescribing a more expensive brand when a cheaper one is available can burden the patient financially and thus reduce patient compliance. In addition, the Government should also include more anti-diabetic drugs under the price control policy to ensure that affordable and efficacious medicines are available to all. Keywords: Anti-diabetic agents, Cost variation, Pharmaco-economics, Adherence, Brands   Background:  Diabetes mellitus (DM) is a chronic metabolic disorder requiring lifelong treatment. Due to rapid expansion of urbanization, unhealthy diet habits and sedentary life style, the incidence of DM is increasing .The chronic nature of DM causes significant personal suffering and economic difficulty to families. The present study aims at investigating the cost difference in various brands of the same oral anti-diabetic drug.Methods: The minimum and the maximum cost in rupees (INR) of a particular anti-diabetic drug manufactured by various brands were obtained from Current Index of Medical Specialties (CIMS) website, Indian Drug Review (IDR) 2021 issue and National Pharmaceutical Pricing Authority – Pharma sahi daam. The cost ratio and percentage cost variation were noted for each brand.Results: Amongst single drug therapy, Metformin 500mg Sustained Release showed highest price variation (3668%). Minimum cost variation was found with Glipizide 2.5mg (65%).Amongst the fixed dose combinations, highest cost variation was seen with Glimepiride 2mg + Metformin 1000mg (2703%) while minimum cost variation was found with Repaglinide 1mg + Voglibose 0.3mg (29%). Conclusions: A noticeable cost variation was found in different brands of the same anti-diabetic drug. Prescribing a more expensive brand when a cheaper one is available can burden the patient financially and thus reduce patient compliance. In addition, the Government should also include more anti-diabetic drugs under the price control policy to ensure that affordable and efficacious medicines are available to all. Keywords: Anti-diabetic agents, Cost variation, Pharmaco-economics, Adherence, Brands   Background:  Diabetes mellitus (DM) is a chronic metabolic disorder requiring lifelong treatment. Due to rapid expansion of urbanization, unhealthy diet habits and sedentary life style, the incidence of DM is increasing .The chronic nature of DM causes significant personal suffering and economic difficulty to families. The present study aims at investigating the cost difference in various brands of the same oral anti-diabetic drug.Methods: The minimum and the maximum cost in rupees (INR) of a particular anti-diabetic drug manufactured by various brands were obtained from Current Index of Medical Specialties (CIMS) website, Indian Drug Review (IDR) 2021 issue and National Pharmaceutical Pricing Authority – Pharma sahi daam. The cost ratio and percentage cost variation were noted for each brand.Results: Amongst single drug therapy, Metformin 500mg Sustained Release showed highest price variation (3668%). Minimum cost variation was found with Glipizide 2.5mg (65%).Amongst the fixed dose combinations, highest cost variation was seen with Glimepiride 2mg + Metformin 1000mg (2703%) while minimum cost variation was found with Repaglinide 1mg + Voglibose 0.3mg (29%). Conclusions: A noticeable cost variation was found in different brands of the same anti-diabetic drug. Prescribing a more expensive brand when a cheaper one is available can burden the patient financially and thus reduce patient compliance. In addition, the Government should also include more anti-diabetic drugs under the price control policy to ensure that affordable and efficacious medicines are available to all. Keywords: Anti-diabetic agents, Cost variation, Pharmaco-economics, Adherence, Brands         

scholarly journals Cost variation analysis of antihypertensive drugs acting through renin angiotensin aldosterone axis modulation

2017 ◽  
Vol 6 (5) ◽  
pp. 1085
Author(s):  
Manju K. Nair ◽  
Neha M. S.
Keyword(s):  
Dosage Form ◽  
Antihypertensive Drugs ◽  
Cost Effective ◽  
Cost Ratio ◽  
Microsoft Excel ◽  
Medical Specialties ◽  
Renin Angiotensin ◽  
Cost Variation ◽  
Rational Drug ◽  
The Cost

Background: Several brands of antihypertensive drugs are available in the Indian market with huge price variations. This study was undertaken to find out the percentage cost variation and cost ratio of antihypertensive drugs acting through renin angiotensin aldosterone axis modulation.Methods: Costs of different brands of renin angiotensin aldosterone axis modulatory drugs with antihypertensive action for the same dosage form and strength were found out using current index of medical specialties-134, July-October 2016. The maximum and minimum price of different brands of each drug was noted. Data was entered in Microsoft excel 2010. Percentage cost variation and cost ratio was calculated for each drug.Results: 16 antihypertensive drugs were analysed. Most of them were tablets. Ramipril and Valsartan were available as capsules also. Among tablets, percentage cost variation was highest for Atenolol 12.5 mg (683.93%) and least for Bisoprolol 2.5 mg (3.6538%). Valsartan capsules (160 mg) had no difference in the costs between the available 2 brands. Cost ratio ranged from 1.04 to 7.84 among the tablet form of drugs.Conclusions: There is a huge difference in the cost of antihypertensive drugs manufactured by different companies in the same strength and dosage form. To promote rational drug use and cost effective therapy, it is essential to create an awareness among clinicians regarding the availability of multiple brands for these drugs and the discrepancies in their costs.

scholarly journals Cost Excursion Study of Various Insulin Preparations Available in India

2021 ◽  
Author(s):  
Mayur B Phulpagare ◽  
Smita A Tiwari ◽  
Rajesh S Hiray
Keyword(s):  
Insulin Analogue ◽  
Insulin Analogues ◽  
Cost Ratio ◽  
Diabetic Patients ◽  
Pharmaceutical Pricing ◽  
Medication Regimen ◽  
Price Variation ◽  
Medical Specialties ◽  
Antidiabetic Treatment ◽  
Cost Variation

Introduction: Poor drug compliance affects clinical outcome and increases healthcare costs in various disease setting. Several type II diabetes mellitus patients, not controlled on oral hypoglycaemics eventually require insulin therapy. Antidiabetic treatment is to be taken lifelong and in such a setting insulin price variation imposes a huge economic burden on poor diabetic patients. Moderating drug cost is associated with improved adherence to the medication regimen. Aim: To study the variation in cost amongst various brands of insulin analogues. Materials and Methods: This was an observational, cross-sectional study. Data regarding the 116 formulations and cost of 18 types of insulin preparations was collected from sources like Current Index of Medical Specialties (CIMS), National Pharmaceutical Pricing Authority (NPPA), Government of India official website (https://nppaimis.nic.in/nppaprice/pharmasahidaamweb.aspx) and compared with its lowest counterpart. The cost ratio and percentage cost variation was analysed and expressed as percentages. Results: This study showed a noticeable variation in the prices of insulin analogues. The highest percentage of cost variation was found for Insulin (Highly Purified) Zinc-40 IU (135.17%), followed by Insulin (Analogue) Glargine-100 IU (109.31%). The lowest percentage were for: Insulin (Human-Isophane Recombinant)-40 IU (1.40%), and Insulin (Analogue) Aspart- 100 IU (6.26%). Conclusion: A noticeable variation in cost prices was observed especially in commonly used intermediate acting insulin that help basal glycaemic control. Similarly, the lowest variation was observed with recombinant counterparts as an effect of pre-existing high prices of each. Need for vital medication like insulin at affordable costs has incited national and global efforts to make it cheaper and accessible to maximum beneficiaries.

scholarly journals Cost variation among antiretroviral drugs: pharamcoeconomical prospective

2018 ◽  
Vol 7 (4) ◽  
pp. 594
Author(s):  
Dinesh Jiwane ◽  
Arun Kumar Srivastav ◽  
Neelesh Arya ◽  
Mithlesh Mehar
Keyword(s):  
Opportunistic Infections ◽  
Financial Burden ◽  
Drug Regimen ◽  
Antiretroviral Drugs ◽  
Cost Ratio ◽  
Combination Drug ◽  
Price Variation ◽  
Medical Specialties ◽  
Cost Variation ◽  
Wide Range

Background: Acquired immunodeficiency syndrome (AIDS) is a disorder caused by the human immunodeficiency virus (HIV). Main characteristic feature of AIDS includes severe immunosuppression which leads to opportunistic infections which is a main cause of death and requires a lifelong therapy. There exists wide range of cost variation in antiretroviral drugs that are marketed in India. The current study aims to view the existing situation of antiretroviral drugs, by collecting data about the cost of common antiretroviral drugs available either singly or in combination and to evaluate the difference in cost of different brands of same active drug by calculating percentage cost variation.Methods: Data for calculating cost ratio and percentage price variation of various antiretroviral drugs was obtained from “Current Index of Medical Specialties” October 2017-January2018.Results: Zidovudine 100mg shows maximum cost ratio and price variation followed by Lamivudin 100mg in the single drug therapy. Lamivudine 150mg + Zidovudine 300mg shows maximum price variation in combination drug therapy.Conclusions: Indian market shows wide price variation of different brands of the same generic antiretroviral drug. To decrease the wide cost variation among different brands of antiretroviral drugs; it is time to create awareness among healthcare professionals about impact of cost effectiveness of drug regimen and decrease the financial burden on the patients.

scholarly journals Cost variation analysis of ACE inhibitors in India

2017 ◽  
Vol 6 (6) ◽  
pp. 1522
Author(s):  
Prashant Wadagbalkar ◽  
Poonam Patel ◽  
Swati V. Raipurkar
Keyword(s):  
Ace Inhibitors ◽  
Antihypertensive Drugs ◽  
Patient Adherence ◽  
Antihypertensive Agents ◽  
Cost Ratio ◽  
Medical Specialties ◽  
Single Drug ◽  
Cost Variation ◽  
The Difference ◽  
The Cost

Background: Cardiovascular diseases are the most prevalent cause of death and disability in developed and developing countries. There is a wide variation in the prices of antihypertensive drugs marketed in India. Thus, a study was planned to find out variation in cost in the ACE Inhibitors available in India either as a single drug or in combination and to evaluate the difference in cost of various brands of the same ACE Inhibitors and ARBs by calculating percentage variation in cost in Indian rupees.Methods: Minimum and maximum costs in rupees (INR) of antihypertensive agents manufactured by different companies, in the same strength and dosage forms were obtained from “current index of medical specialties” January April 2016 and Drug Today October-December 2016. The cost ratio and percentage cost variation were calculated for each generic antihypertensive agent (ACE Inhibitors and ARBs).Results: This study shows that there is a wide variation in the prices of different brands of same ACE Inhibitors and ARBs in Indian market.Highest cost variation 400% is for Lisinopril (2.5mg), followed by Enalapril (10mg) 394.16%, Telmisartan (20mg) 322.22%.Conclusions: There is a wide difference in the cost of different brands of ACE Inhibitors and ARBs available in India. They have important role in management of hypertension particularly if associated with other morbidities like diabetes. The clinicians prescribing these drugs should be aware of these variations in cost so as to reduce the cost of drug therapy and increase the patient adherence to the therapy.

scholarly journals Cost variation among anxiolytic drugs

2018 ◽  
Vol 7 (3) ◽  
pp. 405
Author(s):  
Ajay Kumar Shukla ◽  
Neelesh Arya
Keyword(s):  
Anxiety Disorders ◽  
Term Treatment ◽  
Mental Illnesses ◽  
Variable Cost ◽  
Cost Ratio ◽  
Indian Market ◽  
Medical Specialties ◽  
Cost Variation ◽  
Long Term Treatment ◽  
Anxiolytic Drugs

Background: Indian pharmaceuticals market stands third and thirteenth largest in terms of value and volume in the Global Pharmaceutical Industry respectively. Anxiety disorders are one of the most common mental illnesses affecting more than 15% of the population at some point in their life span. Treatment of anxiety disorders usually follows a long term treatment. Cost of the treatment is an important factor determining the adherence to the treatment.Methods: Data relevant to various brands of anxiolytic drug available in the Indian market particular drug obtained from “Current Index of Medical Specialties” (CIMS) October 2017 - January 2018 was used to calculate the cost ratio and percentage cost variation.Results: There are 16 anxiolytic drugs in the form of 44 different formulations and 384 brands available in the Indian market. Among anxiolytic drugs, highest cost ratio and percent cost variation is for diazepam 5mg, followed by alprazolam 1mg and hydroxyzine 10mg. Highest number of brands of anxiolytic drugs available in Indian market are for clonazepam 0.5mg followed by alprazolam 0.5mg and escitalopram 10mg.Conclusions: In Indian market, there is availability of large number of brands with wide and variable cost variations among the various brands of the anxiolytic drugs.

scholarly journals Cost analysis of various topical eye preparations currently available in Indian market

2019 ◽  
Vol 8 (8) ◽  
pp. 1754
Author(s):  
Shweta Agrawal ◽  
Neelesh Arya ◽  
Mehul Agrawal
Keyword(s):  
Cost Ratio ◽  
Eye Drops ◽  
Drug Formulations ◽  
Medical Specialties ◽  
Cost Variation ◽  
Long Run ◽  
The Common ◽  
Cost Of Drugs ◽  
The Cost ◽  
Indian Pharmaceutical Industry

Background: topical eye preparations are very commonly used in India for different eye diseases hence their prices should not be much different in Indian pharmaceutical industry. The common man therefore has to shell out more money with medicine prices spinning out of his reach. Aim of this study was to compare the cost of drugs of the different brand of topical ophthalmic drugs.Methods: cost of various topical eye preparations was compared using “Current Index of Medical Specialties” (CIMS) January-April 2019 and cost variation was recorded. Drugs were categorized into anti-infective and antiseptics, topical corticosteroids, mydriatics, anti-glaucoma drugs, anti-inflammatory and lubricants.Results: That of the 26 drug formulations studied, the percentage cost variation of 10 drug formulations was more than 100%, out of which one formulation of moxifloxacin had more than 1000% variation. Cost ratio of 10 drug formulations were more than two. Moxifloxacin 0.5% eye drops had maximum percentage cost variation of 5610.66% and cost ratio of 57.11, followed by ofloxacin 0.30% eye drops (310.92%, 4.11), timolol 0.50% eye drops (263.64%, 3.64), ciprofloxacin 0.30% eye drops (142.42%, 2.42), tobramycin 0.30% eye drops (120.14%, 2.20).Conclusions: There is a significant variation in the price of various topical eye preparations. As most of the preparations being prescribed on an out-patient basis, which was not covered under most of the insurance program. Out of pocket expenditure adversely affects the drug compliance in the long run. There should be a comprehensive action from policymakers, regulatory authorities, government agencies, doctors, pharmacists, and the general public to solve this issue of cost variation of drugs.

scholarly journals Study of the Variation in Prices of Antidepressant Drugs Available in Nepali Market

2020 ◽  
Vol 5 (2) ◽  
pp. 1006-1010
Author(s):  
Anjan Khadka ◽  
Pradeep Manandhar ◽  
Nagendra Katuwal ◽  
Mahesh Khatri
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Antidepressant Drugs ◽  
Cost Ratio ◽  
Care Hospital ◽  
Cross Sectional ◽  
Medical Specialties ◽  
Cost Variation ◽  
Multiple Drugs ◽  
The Cost

Introduction: Depression often remains unrecognized, misdiagnosed and/or under treated. There are multiple drugs from multiple companies which are available for treatment of depression. The prices of same drug with different brands are variable which questions the afford ability of treatment to the patients and their compliance. Objective The study was conducted to analyze the cost variation of different brands of antidepressant drugs prescribed in a tertiary care hospital of Nepal. Methodology This study design was cross-sectional and method was quantitative method and conducted at department of pharmacology of a tertiary care hospital from September 2018 to January 2019 after getting approval from institutional review committee. The commonly prescribed antidepressant drugs were recorded from prescription records of department of psychiatry and their cost, cost ratio and percentage variation were calculated as per current index of medical specialties and National index of medical specialties. The data were recorded in MS excel and presented as simple descriptive statistics. Result The study included seven commonly prescribed antidepressants obtained from 214 prescription records. The cost of one course of citalopram 40 mg tablet was found to be higher and the cost of one course of imipramine 25 mg tablet was found to be lower. The maximum and minimum cost ratio was 2.46 and 1.08 with fluoxetine 20 mg capsule and dothiepin 50 mg tablet respectively. The maximum and minimum percentage of cost variation was with fluoxetine 20 mg capsule and dothiepin 50 mg tablet. Conclusion Costs of antidepressants had wider variations depending on the manufacturers and availability of different dose and brands.

scholarly journals Cost analysis of antipsychotic drugs available in India

2017 ◽  
Vol 6 (3) ◽  
pp. 669
Author(s):  
Ajay Kumar Shukla ◽  
Astha Agnihotri
Keyword(s):  
Antipsychotic Drug ◽  
Antipsychotic Drugs ◽  
Cost Ratio ◽  
Indian Market ◽  
Price Variation ◽  
Average Percentage ◽  
Cost Variation ◽  
Wide Range ◽  
The Government ◽  
The Cost

Background: Indian drug market has large numbers of branded formulations for every drug molecule. 1 Cost-sensitive healthcare environment has created a challenging workplace for clinicians. Efficient use of healthcare resources without compromising quality of patient care has been a challenging task for healthcare professionals. There is a wide range of variation in the prices of drugs marketed in India. Thus, a study was planned to analyse out cost variations of antiepileptic drugs available in Indian market.Methods: Minimum and maximum costs in Rupees (INR) of different brands of same generic antipsychotic drugs, in the same strength and dosage forms were compared. The cost ratio and percentage cost variation were calculated for each generic antipsychotic drug. The number of formulations for antipsychotic drugs and number of brands for each of them were also taken into consideration.Results: This study shows that in Indian market, there are wide variations in the prices of different brands of same generic antipsychotic drug. The highest cost ratio and percent cost variation was found for risperidone 2 mg [(1:16.27) and 1527.48], followed by risperidone 4 mg [(1:16.25) and 1525.25], risperidone 3 mg [(1:15.67) and 1467.33], risperidone 1 mg [(1:14.86) and 1386.78], olanzapine 10 mg [(1:12.36) and 1136.84], and olanzapine 5 mg [(1:12.31) and 1130.76]. Highest number of brands of antipsychotic drug available in Indian market are for divalproex sodium 500mg(25) followed by olanzapine 15 mg(23), olanzapine 5 mg(23), olanzapine 2.5mg(14), and risperidone 1 mg (14). Highest numbers of formulations of antipsychotic drug available in Indian market are for olanzapine(06), quetiapine(05), haloperidol(05), and aripiprazole(05).Conclusions: In Indian market, the average percentage price variation of different brands of the same oral antipsychotic drugs is very wide. Treatment with antipsychotic drugs usually has a long course with treatment adherence being a crucial factor for successful treatment. Improved adherence to the drug treatment can be ensured by decreasing the cost of therapy. Decreased drug cost expenditure can be ensured by changes in the government policies and regulations, integrating pharmacoeconomics as part of medical education curriculum, and creating awareness among treating physicians for switching to cost effective therapy.

scholarly journals Cost variation analysis of various brands of topical eye preparations currently available in Indian pharmaceutical market

2018 ◽  
Vol 7 (12) ◽  
pp. 2364
Author(s):  
Shukrath Chandrappa ◽  
Kavitha Rajarathna
Keyword(s):  
Drug Delivery ◽  
Financial Burden ◽  
Cost Effective ◽  
Topical Administration ◽  
Brand Names ◽  
Cost Ratio ◽  
Drug Formulations ◽  
Cost Variation ◽  
Cost Effective Treatment ◽  
The Cost

Background: Ocular drug delivery is a complex drug delivery system, and topical administration being the most frequently employed route of drug delivery in eye diseases. Many topical eye preparations are sold under brand names. The variation in the costs of the same drug and inadequate information on quality and bio-equivalence makes it difficult for the physician to prescribe the most cost-effective treatment. The objective of this study was to analyse the cost variation in different brands of commonly used topical eye preparations in India.Methods: The minimum and the maximum cost in Rupees (INR) of particular topical eye preparations manufactured by various pharmaceutical companies in the same strength were noted. The percentage cost variation and cost ratio were calculated for each brand.Results: The costs of the total of 19 topical eye preparations available in 26 different formulations in India were analysed and a substantial variation in cost was observed. Of 19 drug formulations studied, the percentage cost variation of 10 drug formulations was more than 100% out of which one had more than 1000% variation. Cost ratio was also observed to be very high and 10 drug formulations had this ratio more than two.Conclusions: There is a wide variation in the prices of different brands, so there is an urgent need to raise the awareness of physicians about cost variation to lower the financial burden on patients.

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