scholarly journals Efficacy of misoprostol over Foley’s catheter as a cervical ripening agent: a comparative study

2017 ◽  
Vol 6 (12) ◽  
pp. 5288
Author(s):  
Pankajkumar B. Nimbalkar ◽  
Jaldhara N. Patel ◽  
Nilesh Thakor
Keyword(s):  
Foley Catheter ◽  
Age Groups ◽  
Cervical Ripening ◽  
Mortality And Morbidity ◽  
Medical College ◽  
Catheter Group ◽  
Misoprostol Group ◽  
Vaginal Misoprostol ◽  
Foley’S Catheter ◽  
Age Range

Background: Timely induction of labour could reduce maternal mortality and morbidity as well as assure a delivery of healthy baby. Objective of present study was to evaluate the efficacy of Misoprostol as a cervical ripening agent and its comparison with Foley’s catheter in terms of success rate, safety, side effects and patient compliance.Methods: A total of 250 pregnant women requiring induction of labor were recruited. Out of 250 cases, 150 were induced with 50 microgram Misoprostol and in 100 cases Foley catheter 18 F, was placed through the internal os of the cervix during September 2014 to August 2017 at the department of Obstetrics and Gynecology, GMERS Medical College, Dharpur-Patan. Written and informed consent was taken from the patients. Outcome measures, such as change in Bishop's score, need of augmentation, induction delivery interval; complications like hyperstimulation, fever and meconium passage were compared between two groups. Statistical analysis was performed by Epi Info 7.Results: Age range of the patients was 21 to 35 years. 72.4 % of the patients were in 21-25 years age groups. 54.4% patients were multigravida. 59.2% patients had more than 37 weeks of pregnancy. 46.4% of the patients had premature rupture of membrane as indication of labour. The mean Bishop's score for induction was 3.21 in Misoprostol group. 81.3% patients in Misoprostol group and 88% of patients in Foley’s catheter group were delivered by vaginal delivery. 60 % patients delivered within 6 hours in Misoprostol group. (Misoprostol: 60%, Foley’s catheter: 9%, p<0.001) Incidence of thin meconium was 11.3% in Misoprostol group, 9 % in Foley’s catheter group. In Misoprostol group 3.3 women had fever after induction while it was 6% in Foley’s catheter group.Conclusions: The results of the present study confirm that vaginal misoprostol is more effective than Foleys catheter in pre-induction cervical ripening.

scholarly journals Efficacy of misoprostol over dinoprostone gel as a cervical ripening agent: a comparative study

2017 ◽  
Vol 6 (12) ◽  
pp. 5251 ◽  
Author(s):  
Pankajkumar B. Nimbalkar ◽  
Jaldhara N. Patel ◽  
Nilesh Thakor
Keyword(s):  
Age Groups ◽  
Induction Of Labor ◽  
Cervical Ripening ◽  
Healthy Baby ◽  
Mortality And Morbidity ◽  
Medical College ◽  
Maternal Mortality And Morbidity ◽  
Misoprostol Group ◽  
Vaginal Misoprostol ◽  
Age Range

Background: Timely induction of labour could reduce maternal mortality and morbidity as well as assure a delivery of healthy baby. The objective of this study was to evaluate the efficacy of Misoprostol as a cervical ripening agent and its comparison with Dinoprostone gel in terms of success rate, safety, side effects and patient compliance.Methods: A total of 250 pregnant women requiring induction of labor were recruited. Out of 250 cases, 150 were induced with 50 microgram Misoprostol and 100 cases with 0.5 mg intracervical Dinoprostone gel during September 2014 to August 2017 at the department of Obstetrics and Gynaecology, GMERS Medical College, Dharpur-Patan. Written and informed consent was taken from the patients. Outcome measures, such as change in Bishop's score, need of augmentation, induction delivery interval; complications like hyperstimulation, fever and meconium passage were compared between two groups. Statistical analysis was performed by Epi Info 7.Results: Age range of the patients was 21 to 35 years. 74.8% of the patients were in 21-25 years age groups. 50.4% patients were multigravida. 57.6% patients had more than 37 weeks of pregnancy. 50.4% of the patients had premature rupture of membrane as indication of labour. The mean Bishop's score for induction was 3.21 in Misoprostol group. 81.3% patients in Misoprostol group and 93% of patients in Dinoprostone group were delivered by vaginal delivery. 60% patients delivered within 6 hours in Misoprostol group. (Misoprostol: 60%, Dinoprostone: 27%, p<0.001). Incidence of thin meconium was 11.3% in Misoprostol group, 9% in Dinoprostone group. In Misoprostol group 3.3 women had fever after induction.Conclusions: Vaginal misoprostol is more efficacious in cervical ripening and for induction of labor than Dinoprostone.

scholarly journals Comparative study of vaginal misoprostol and intra cervical Foley’s catheter for pre-induction cervical ripening at term

2017 ◽  
Vol 6 (4) ◽  
pp. 1283
Author(s):  
Meghna Agarwal ◽  
Varsha Kose
Keyword(s):  
Pregnant Women ◽  
Vaginal Delivery ◽  
Foley Catheter ◽  
Cervical Ripening ◽  
Catheter Group ◽  
Misoprostol Group ◽  
Group 2 ◽  
Vaginal Misoprostol ◽  
Foley’S Catheter ◽  
Group 1

Background: At times of unfavorable cervix induction of labor with cervical ripening agents were necessary. The present study was done to compare the efficacy and outcome of vaginal misoprostol and Foleys catheter in pregnant women for induction of labor.Methods: This randomized clinical trial was performed on 10o pregnant women during a time period of December 2014 to November 2016. These women were randomly divided into two groups: Misoprostol (50 patients) and Foley catheter (50 patients). For the first group, 25 mcg vaginal misoprostol was administered every 4 h up to maximum of 3 doses for a period of 12 hours. For the second group, Foley catheter 18 F, was placed through the internal os of the cervix. Data was analyzed using SPSS software 20. p <0.05 was considered statistically significant.Results: The mean age of the patients in Group 1 was 24.72±2.93 years and Group 2 was 24.12±2.88 years. Pre-induction & post-induction modified Bishop score was significantly higher in Group 1 (Misoprostol) as compared to Group 2 (Foley's catheter) in primigravida and multigravida patients. The difference in the birth weight and Apgar score at 1 min and 5 min between the two groups was statistically not significant (p>0.05). The rate of vaginal delivery was significantly more in Misoprostol group as compared to Foley’s catheter group (p<0.05). The caesarean section rate was more in Foley’s catheter group as compared to Misoprostol group and the results were statistically significant (p<0.05).Conclusions: It was concluded that misoprostol decrease the delivery time and increases the vaginal delivery compared to Foleys catheter.

scholarly journals Comparison of low dose vaginal misoprostol with Foley catheter balloon as preinduction cervical ripening agents in term pregnancies

2020 ◽  
Vol 1 ◽  
pp. 10
Author(s):  
Dalyop Davou Nyango ◽  
Daloek M ◽  
Kahansim ML
Keyword(s):  
Pregnant Women ◽  
Low Dose ◽  
Foley Catheter ◽  
Comparative Trial ◽  
Tertiary Hospital ◽  
Cervical Ripening ◽  
Catheter Group ◽  
Misoprostol Group ◽  
Uterine Hyperstimulation ◽  
Vaginal Misoprostol

Objective: One of the obstetricians’ nightmare is managing high-risk pregnancies. Also, the emerging trend by pregnant women requesting for specific delivery dates for social reasons adds to this burden. In both instances, the obstetrician is faced with the challenge of inducing labor where the cervix is still unfavorable. The objective of the study was to compare the effectiveness of loe dose vaginal misoprostol and transcervical extra-amniotic Foley catheter balloon as pre-induction cervical ripening agents in term pregnancies. Material and Methods: This was a prospective, single-blind, randomized comparative trial at a tertiary hospital. Pregnant women at term in whom induction of labor was indicated, who made the inclusion criteria and who gave their consent were randomly assigned to either the vaginal misoprostol or the Foley catheter balloon group. Oxytocin was used for the augmentation of labor subsequent to the artificial rupture of the membranes according to the departmental protocols. Results: One hundred and fifty women were recruited and randomized (75 in each group). In the misoprostol group, 58 (77.3%) women achieved cervical ripening (cervical dilation of ≥4) within 12 h, compared to 43 (57.3%) in the Foley catheter balloon group. Spontaneous vaginal delivery within 12 h was 88.0% and 66.3% in the misoprostol and Foley catheter group, respectively. However, 34.7% in misoprostol group had precipitate labor (induction-to-delivery interval ≤3 h), while 9.3% in the Foley catheter group had prolonged labor. There were no significant differences in the incidence of meconium staining and 1st min Apgar scores of the babies in the two groups. Conclusion: Low dose (25 μg) vaginal misoprostol is a more effective pre-induction cervical ripening agent compared to the conventional transcervical extra-amniotic Foley catheter balloon method. While uterine hyperstimulation is the major risk in the misoprostol group, long induction-to-delivery interval is associated with labors induced following use of Foley catheter balloon as the pre-induction cervical ripening agent.

scholarly journals Cervical Ripening: Comparative Study between Intracervical Balooning by Foley’s Catheter and Intravaginal Misoprostol Tablet

1970 ◽  
Vol 27 (1) ◽  
pp. 5-12
Author(s):  
Jannatul A Ferdous ◽  
Nurun Nahar Khanam ◽  
Most. Rashida Begum ◽  
Sayeba Akhter
Keyword(s):  
Mode Of Delivery ◽  
Fetal Outcome ◽  
Induction Of Labor ◽  
Cervical Ripening ◽  
College Hospital ◽  
Socioeconomic Condition ◽  
Medical College ◽  
Catheter Group ◽  
Misoprostol Group ◽  
Foley’S Catheter

This study was designed to compare the effectiveness of misoprostol and Foley's catheter on cervical ripening. A randomized clinical trial was carried out at Dhaka Medical College Hospital during the period from March 2002 to November 2002. Ninety patients, who were chosen for induction, were selected for this study, 45 patients were randomly selected for Foley's catheter group and 45 patients for misoprostol group by using lottery. The baseline characteristics like age, parity, socioeconomic condition, gestational age; Bishop's score and indication of induction of labor were almost same in both groups. Mean duration of onset of labour was 13.60±5.0 and 15.26±3.58 hours, induction-full dilatation was 18.83±2.94 and 20.03±2.46 hours and induction-delivery interval was 20.04±2.82 and 21.18±2.32 hours in the misoprostol and Foley's catheter groups respectively. The differences were not significant. Mode of delivery and fetal outcome were also same in both group. Complications like vomiting and hyperstimulation appeared in few cases in misoprostol group but not significant. From this study, it was found that the safety and efficacy of Foley's catheter is comparable to misoprostol. In addition, Foley's catheter is free from some side effects of misoprostol, like vomiting and hyperstimulation. Therefore, Foley's catheter can be used for cervical ripening. Key words: Induction of labor, Foley's catheter, misoprostol DOI: 10.3329/jbcps.v27i1.4237 J Bangladesh Coll Phys Surg 2009; 27: 5-12

scholarly journals Intravaginal Misoprostol versus Transcervical Foley Catheter for Pre-Induction Cervical Ripening and their Outcome - A Comparative Study

2016 ◽  
Vol 27 (2) ◽  
pp. 72-78
Author(s):  
Sabiha Nazneen ◽  
Ferdousi Sultana ◽  
Kamrun Nahaer
Keyword(s):  
Caesarean Section Rate ◽  
Foley Catheter ◽  
Mode Of Delivery ◽  
Cervical Ripening ◽  
Socioeconomic Condition ◽  
Medical College ◽  
Catheter Group ◽  
Significant Difference ◽  
Misoprostol Group ◽  
Mean Time

Objective : To compare the efficacy of transcervical Foley Catheter and Intravaginal Misoprostol in pre-induction cervical ripeningMaterials & Methods : This crosssectional study was done in the inpatient dept. of obs. and gynae at the Rangpur Medical College and Hospital, Rangpur, Bangladesh between 1st July 2005 to 30th December, 2006. During 18 (eighteen) months of study period, 99 patients were enrolled, 50 were in group 1 where Misoprostol tablet was given vaginally and 49 were in group II where Foley Catheter was used transcervically. The Misoprostol tablet dosing regime was 50?g (one- fourth of a 200?g tablet), which was given vaginally (in the posterior vaginal fornix). The second dose was given after six hours. Though the maximum target was four doses that was 200?g, cervical ripening took place in all the cases with only two doses. Cervical scoring was reassessed after four hours in both the groups.Results: There were similar baseline characteristics such as age of the patients, socioeconomic condition etc. No significant difference was observed regarding parity, gravidity, gestational age, Bishop’s score and pre-induction of labour. There was also no significant difference in the mean time of pre-induction to delivery interval, mode of delivery and neonatal out come. Change in Bishop’s score was similar in both groups but more time was required from pre-induction to delivery in Foley catheter group. The most frequent complaint in Foley catheter group was mild discomfort at insertion. Vaginal delivery was higher in this group (63.3%) whereas Caesarean section rate was higher in Misoprostol group (36%) due to hyperstimulation syndrome.Conclusion: Both intravaginal Misoprostol and transcervical Foley catheter have similar effectiveness as pre-induction agents in unripe cervix. Transcervical Foley catheter is associated with a lower incidence of hyperstimulation syndrome (presence of hypertonous utrine contraction associated with abnormal foetal heart rate) and higher incidence of vaginal deliveries.Bangladesh J Obstet Gynaecol, 2012; Vol. 27(2) : 72-78

scholarly journals Comparative Evaluation of Pre-Induction Changes in Bishop’s Score with Insertion of Intra-Cervical Foley Catheter and Vaginal Misoprostol

2018 ◽  
Vol 12 (2) ◽  
pp. 69-73
Author(s):  
Anju Mandal
Keyword(s):  
Comparative Study ◽  
Comparative Evaluation ◽  
Foley Catheter ◽  
Medical Science ◽  
Catheter Group ◽  
Misoprostol Group ◽  
The Mean ◽  
Vaginal Misoprostol ◽  
Foley’S Catheter

Aim: The aim of this study was to compare changes in pre-induction Bishop’s Score with insertion of intra-cervical Foley catheter and vaginal Misoprostol administration for cervical ripening.Methods: It is a comparative study done among 50 patients at term that had Bishop’s score <5 in College of Medical Science in Bharatpur. Intra-cervical Foley catheter was used in half of the women and intra-vaginal insertion of 50 microgram Misoprostol tablet was used in the rest. After 24 hours of post ripening, Bishop’s score was noted and labour was induced with inj. oxytocin if required.Results: Both groups showed significant changes in the mean Bishop’s score after ripening agents, 7.64 and 7.25 for Foley catheter group and Misoprostol group respectively. Eighty four percent patients from Foley catheter group and 72% patient from Misoprostol had normal delivery.Conclusion: Post ripening mean Bishop’s score was significantly better in Foley catheter group as compared to Misoprostol group.The induction to labour interval, induction to delivery interval and labour to delivery interval were less in Foley’s catheter group than Misoprostol group.

scholarly journals Efficacy of vaginal Misoprostol versus transcervical Foley’s catheter and vaginal Misoprostol in induction of labor

2019 ◽  
Vol 8 (4) ◽  
pp. 1341
Author(s):  
Vijayalaxmi Davalagi ◽  
Lakshmikantha G. ◽  
Neeta .
Keyword(s):  
Induction Of Labor ◽  
Comparative Efficacy ◽  
Catheter Group ◽  
Misoprostol Group ◽  
The Common ◽  
Vaginal Misoprostol ◽  
Foley’S Catheter ◽  
Labour Room ◽  
A Prospective Study ◽  
Failure Of Induction

Background: The objective is to compare the efficacy of vaginal Misoprostol versus transcervical Foley’s catheter and vaginal Misoprostol.Methods: A prospective study analyzing the comparative efficacy of intravaginal instillation of Misoprostol in two groups (tablet Misoprostol 50mg alone and combination of intracervical Foley’s catheter and tablet Misoprostol 50mg) carried out in the labour room on 300 subjects (150 subjects in each group), from May 2013 to November 2015.Results: The common gestational age at the time of induction was 36-40 weeks and the most common indication was premature rupture of membrane. In both the groups, most of the cases delivered within 12 hours. present results show that statistically significant number of cases delivered vaginally within 12 hours with the group using Misoprostol plus Foley’s catheter as compared to the group using Misoprostol alone. Cesarean section rate was 12.67% in Misoprostol group and 10.67% in Misoprostol plus Foley’s catheter group. Incidence of failure of induction was similar in both the groups. The incidence of babies with Apgar score less than 8/10 at 5 minutes and incidence of early neonatal death were similar in both the groups.Conclusions: Addition of intracervical Foley’s catheter to vaginal Misoprostol for induction of labor in subjects with unfavorable cervices reduces the Induction-Delivery interval without added side effects or complications to the mother and fetus.

scholarly journals Postpartum Vaginal Blood Loss following Two Different Methods of Cervical Ripening

2017 ◽  
Vol 2017 ◽  
pp. 1-6
Author(s):  
Okon Asuquo Okon ◽  
John Egede Ekabua
Keyword(s):  
Blood Loss ◽  
Foley Catheter ◽  
Induction Of Labor ◽  
Cervical Ripening ◽  
Treatment Groups ◽  
Catheter Group ◽  
Vaginal Deliveries ◽  
Misoprostol Group ◽  
The University ◽  
To Receive

Eighty women undergoing induction of labor at the University of Calabar Teaching Hospital were recruited and randomly allocated into two treatment groups (40 each), to receive either serial 50 µg doses of misoprostol or intracervical Foley catheter. Vaginal blood loss was collected and measured using an under buttocks plastic collection bag and by perineal pad weighing up to 6 hours postpartum. There were no significant differences between the two groups with respect to sociodemographic and obstetric characteristics. Comparison of blood loss in vaginal deliveries between the two groups revealed that subjects in the misoprostol group had significantly higher blood loss than subjects in the Foley catheter group (488 ± 222 versus 326 ± 106, p<0.05). In both groups, there was strong and statistically significant positive correlation between postpartum blood loss and induction delivery interval (r=0.75, p<0.0001; r=0.77, p<0.0001). There were no significant differences in maternal outcomes. In view of this, further study is required to ascertain if lower doses of misoprostol for induction of labor may result in lesser blood loss. This trial is registered with ISRCTN14479515.

scholarly journals Foley Catheter versus Vaginal Misoprostol for Labour Induction

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Nasreen Noor ◽  
Mehkat Ansari ◽  
S. Manazir Ali ◽  
Shazia Parveen
Keyword(s):  
Vaginal Delivery ◽  
Foley Catheter ◽  
Labour Induction ◽  
Sterile Saline ◽  
Group I ◽  
Catheter Group ◽  
Uterine Hyperstimulation ◽  
Spss Software ◽  
Vaginal Misoprostol ◽  
Foley’S Catheter

Objectives. To compare the efficacy and safety of intravaginal misoprostol with transcervical Foley catheter for labour induction.Material and Methods. One hundred and four women with term gestation, with Bishop score < 4, and with various indications for labour induction were randomly divided into two groups. In Group I, 25 μg of misoprostol tablet was placed intravaginally, 4 hourly up to maximum 6 doses. In Group II, Foley catheter 16F was placed through the internal os of the cervix under aseptic condition and then inflated with 50 cc of sterile saline. Statistical analysis was done using SPSS software.Results. The induction to delivery interval was 14.03 ± 7.61 hours versus 18.40 ± 8.02 hours (p<0.01). The rate of vaginal delivery was 76.7% versus 56.8% in misoprostol and transcervical Foley catheter group, respectively. Uterine hyperstimulation was more common with misoprostol. Neonatal outcome was similar in both the groups.Conclusion. Intravaginal misoprostol is associated with a shorter induction to delivery interval as compared to Foley’s catheter and it increases the rate of vaginal delivery in cases of unripe cervix at term. Transcervical Foley catheter is associated with a lower incidence of uterine hyperstimulation during labour.

scholarly journals A study comparing vaginal misoprostol alone with vaginal misoprostol in combination with Foley catheter for cervical ripening and labour induction

2017 ◽  
Vol 6 (2) ◽  
pp. 485 ◽  
Author(s):  
Binti R. Bhatiyani ◽  
Manisha R. Gandhewar ◽  
Swati Kapsikar ◽  
Pradip Gaikwad
Keyword(s):  
Foley Catheter ◽  
Active Phase ◽  
Fetal Distress ◽  
Induction Of Labor ◽  
Cervical Ripening ◽  
Labour Induction ◽  
Combination Group ◽  
Maternal Complications ◽  
Misoprostol Group ◽  
Vaginal Misoprostol

Background: Induction of labor is a commonly practised intervention in modern obstetrics. The objective of this study was to compare the efficacy of vaginal misoprostol alone with vaginal misoprostol in combination with Foley catheter for labour induction. It aims to assess the induction delivery interval, the outcome of labour, the incidence of instrumental delivery and Cesarean section. The neonatal outcomes and maternal complications would also be assessed.Methods: 105 women with singleton viable pregnancies of 28 weeks or more gestation with cephalic presentation, intact membranes and an unfavorable cervix (Bishops score less than 6) were randomly assigned to induction of labor using vaginal misoprostol or Foley catheter in combination with vaginal misoprostol. Women in the misoprostol only group received 25 micrograms of misoprostol per vagina every 4 hours for a maximum of six doses. Whereas women in the combination group received vaginal misoprostol and in addition Foley catheter was introduced through the cervix for 12 hours. Interruption of the trial was done in case of failure to enter the active phase of labour after 24 hours of induction, fetal distress, hyperstimulation, hypersensitivity to drugs.Results: The induction to delivery time was shorter in misoprostol group as compared to the Foley with misoprostol group by 3 hours. There was no significant change in Bishops score after induction with Foley in combination with misoprostol as compared to misoprostol alone. There was no increase in the maternal and fetal complications in the misoprostol group as compared to Foley with misoprostol.Conclusions: Misoprostol alone was more efficacious for ripening and inducing agent as compared to Foley in combination with misoprostol.

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