scholarly journals Foley Catheter versus Vaginal Misoprostol for Labour Induction

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Nasreen Noor ◽  
Mehkat Ansari ◽  
S. Manazir Ali ◽  
Shazia Parveen

Objectives. To compare the efficacy and safety of intravaginal misoprostol with transcervical Foley catheter for labour induction.Material and Methods. One hundred and four women with term gestation, with Bishop score < 4, and with various indications for labour induction were randomly divided into two groups. In Group I, 25 μg of misoprostol tablet was placed intravaginally, 4 hourly up to maximum 6 doses. In Group II, Foley catheter 16F was placed through the internal os of the cervix under aseptic condition and then inflated with 50 cc of sterile saline. Statistical analysis was done using SPSS software.Results. The induction to delivery interval was 14.03 ± 7.61 hours versus 18.40 ± 8.02 hours (p<0.01). The rate of vaginal delivery was 76.7% versus 56.8% in misoprostol and transcervical Foley catheter group, respectively. Uterine hyperstimulation was more common with misoprostol. Neonatal outcome was similar in both the groups.Conclusion. Intravaginal misoprostol is associated with a shorter induction to delivery interval as compared to Foley’s catheter and it increases the rate of vaginal delivery in cases of unripe cervix at term. Transcervical Foley catheter is associated with a lower incidence of uterine hyperstimulation during labour.

Author(s):  
Meghna Agarwal ◽  
Varsha Kose

Background: At times of unfavorable cervix induction of labor with cervical ripening agents were necessary. The present study was done to compare the efficacy and outcome of vaginal misoprostol and Foleys catheter in pregnant women for induction of labor.Methods: This randomized clinical trial was performed on 10o pregnant women during a time period of December 2014 to November 2016. These women were randomly divided into two groups: Misoprostol (50 patients) and Foley catheter (50 patients). For the first group, 25 mcg vaginal misoprostol was administered every 4 h up to maximum of 3 doses for a period of 12 hours. For the second group, Foley catheter 18 F, was placed through the internal os of the cervix. Data was analyzed using SPSS software 20. p <0.05 was considered statistically significant.Results: The mean age of the patients in Group 1 was 24.72±2.93 years and Group 2 was 24.12±2.88 years. Pre-induction & post-induction modified Bishop score was significantly higher in Group 1 (Misoprostol) as compared to Group 2 (Foley's catheter) in primigravida and multigravida patients. The difference in the birth weight and Apgar score at 1 min and 5 min between the two groups was statistically not significant (p>0.05). The rate of vaginal delivery was significantly more in Misoprostol group as compared to Foley’s catheter group (p<0.05). The caesarean section rate was more in Foley’s catheter group as compared to Misoprostol group and the results were statistically significant (p<0.05).Conclusions: It was concluded that misoprostol decrease the delivery time and increases the vaginal delivery compared to Foleys catheter.


2020 ◽  
Vol 3 (1) ◽  
pp. 105-112
Author(s):  
Baburam Dixit Thapa ◽  
Tara Manandhar ◽  
Sarita Sitaula ◽  
Tulasa Basnet

Introduction: Induction of labor is done with the aim of normal vaginal delivery. There are different methods; mechanical like intra-cervical Foley’s or pharmacological agents like misoprostol ordinoprostone. Objectives: To compare sequential use of Foley’s catheter and vaginal misoprostol in comparison with vaginal misoprostol only. Methods: Patients with period of gestation more than or equal to 41 weeks without any complications were assigned randomly according to computer generated randomization into sequential use ofintracervical Foley followed by vaginal misoprostol after 24 hours (sequential group) or vaginalmisoprostol only. Primary outcome was rate of normal vaginal delivery. Secondary outcomes were induction to delivery interval, maternal and fetal morbidity. Results: Rate of normal vaginal delivery in sequential group (n= 353) and misoprostol alone group(n= 356) was 71.6% and 53.3% (p < 0.001) but the time to delivery from induction is statistically more in sequential group (30.3 vs. 11.2 hours, p< 0.001). Maternal outcomes like postpartum hemorrhage, hyper-stimulation syndrome, chorioamnitis and neonatal outcomes like low Apgar score, meconium stained baby and stillbirth are similar in both the groups. Conclusions: The priming of cervix using intracervical Foley catheter before giving vaginalmisoprostol was beneficial in increasing the rate of normal vaginal delivery but it increased the induction to delivery interval.


2020 ◽  
Vol 1 ◽  
pp. 10
Author(s):  
Dalyop Davou Nyango ◽  
Daloek M ◽  
Kahansim ML

Objective: One of the obstetricians’ nightmare is managing high-risk pregnancies. Also, the emerging trend by pregnant women requesting for specific delivery dates for social reasons adds to this burden. In both instances, the obstetrician is faced with the challenge of inducing labor where the cervix is still unfavorable. The objective of the study was to compare the effectiveness of loe dose vaginal misoprostol and transcervical extra-amniotic Foley catheter balloon as pre-induction cervical ripening agents in term pregnancies. Material and Methods: This was a prospective, single-blind, randomized comparative trial at a tertiary hospital. Pregnant women at term in whom induction of labor was indicated, who made the inclusion criteria and who gave their consent were randomly assigned to either the vaginal misoprostol or the Foley catheter balloon group. Oxytocin was used for the augmentation of labor subsequent to the artificial rupture of the membranes according to the departmental protocols. Results: One hundred and fifty women were recruited and randomized (75 in each group). In the misoprostol group, 58 (77.3%) women achieved cervical ripening (cervical dilation of ≥4) within 12 h, compared to 43 (57.3%) in the Foley catheter balloon group. Spontaneous vaginal delivery within 12 h was 88.0% and 66.3% in the misoprostol and Foley catheter group, respectively. However, 34.7% in misoprostol group had precipitate labor (induction-to-delivery interval ≤3 h), while 9.3% in the Foley catheter group had prolonged labor. There were no significant differences in the incidence of meconium staining and 1st min Apgar scores of the babies in the two groups. Conclusion: Low dose (25 μg) vaginal misoprostol is a more effective pre-induction cervical ripening agent compared to the conventional transcervical extra-amniotic Foley catheter balloon method. While uterine hyperstimulation is the major risk in the misoprostol group, long induction-to-delivery interval is associated with labors induced following use of Foley catheter balloon as the pre-induction cervical ripening agent.


2014 ◽  
Vol 3 (2) ◽  
pp. 12-15
Author(s):  
Ernest O Orji

Introduction: A variety of drugs were used for induction of labour, but only oxytocin and prostaglandins have survived critical test of effectivity with a minimum of side effects for mother and child. The objective of this study is to compare efficacy and safety of vaginal misoprostol with transcervical Foley’s catheter and intravenous oxytocin for induction of labour. Methods: Eighty women at term gestation with the Bishops score < 4 with various indications for labour induction were randomly allocated to receive 25 microgram misoprostol vaginally 4 hourly (maximum 6 doses) or transcervical Foley’s catheter with intravenous oxytocin (2mU/minute to a maximum of 32mU/ minute). There were 40 women in each group. Result: In the misoprotol group induction delivery interval was significantly less (5.50 versus 15.0 hours) and successful induction significantly higher (95% versus 75%) as compared to catheter/oxytocin group. There were more cases of hyperstimulation with misoprostol; however neonatal outcome was similar in both groups. There were more vaginal delivery and less caesarean section in misoprostol compared to Foley’s catheter/oxytocin group. Conclusion: Vaginal misoprostol is highly effective, safe to administer as an agent for induction of labour DOI: http://dx.doi.org/10.3126/njog.v3i2.10825   Nepal Journal of Obstetrics and Gynaecology Vol.3(2) 2008; 12-15


BMJ Open ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. e028896
Author(s):  
Soe-Na Choo ◽  
Abhiram Kanneganti ◽  
Muhammad Nur Dinie Bin Abdul Aziz ◽  
Leta Loh ◽  
Carol Hargreaves ◽  
...  

IntroductionLabour induction in women with a previous caesarean delivery currently uses vaginal prostaglandin E2 (PGE2), which carries the risks of uterine hyperstimulation and scar rupture. We aim to compare the efficacy of mechanical labour induction using a transcervically applied Foley catheter balloon (FCB) with PGE2 in affected women attempting trial of labour after caesarean (TOLAC).Methods and analysisThis single-centre non-inferiority prospective, randomised, open, blinded-endpoint study conducted at an academic maternity unit in Singapore will recruit a total of 100 women with one previous uncomplicated caesarean section and no contraindications to vaginal delivery. Eligible consented participants with term singleton pregnancies and unfavourable cervical scores (≤5) requiring labour induction undergo stratified randomisation based on parity and are assigned either FCB (n=50) or PGE2 (n=50). Treatments are applied for up to 12 hours with serial monitoring of the mother and the fetus and serial assessment for improved cervical scores. If the cervix is still unfavourable, participants are allowed a further 12 hours’ observation for cervical ripening. Active labour is initiated by amniotomy at cervical scores of ≥6. The primary outcome is the rate of change in the cervical score, and secondary outcomes include active labour within 24 hours of induction, vaginal delivery, time-to-delivery interval and uterine hyperstimulation. All analyses will be intention-to-treat. The data generated in this trial may guide a change in practice towards mechanical labour induction if this proves efficient and safer for women attempting TOLAC compared with PGE2, to improve labour management in this high-risk population.Ethics and disseminationEthical approval is granted by the Domain Specific Review Board (Domain D) of the National Healthcare Group, Singapore. All adverse events will be reported within 24 hours of notification for assessment of causality. Data will be published and will be available for future meta-analyses.Trial registration numberNCT03471858; Pre-results.


F1000Research ◽  
2012 ◽  
Vol 1 ◽  
pp. 36 ◽  
Author(s):  
Ayman Shabana ◽  
Hesham Salah ◽  
Mohamed Kandil ◽  
Emad Soliman ◽  
Dalia Morsi

Objective: To investigate whether the use of a weighted trans-cervical fluid-filled Foley’s catheter would improve the effectiveness of 400µg vaginal misoprostol regimen in terminating mid-trimester pregnancies.Methods: This study was conducted at the department of Obstetrics and Gynecology, Menofyia University Hospital in Egypt. Fifty eligible primigravidae were allocated into 2 groups. Termination was carried out in group I using vaginal misoprostol while in group II, a weighted fluid-filled intra-uterine Foley’s catheter was inserted and a similar misoprostol regimen was followed as in group I.Results:The combined group showed shorter induction to termination interval (15.6 ± 4.9 versus 21.9 ± 5.4 hours; P<0.05). There was no significant difference in the occurrence of side effects between the groups.Conclusion: A combination of a weighted Foley’s catheter and 400µg of vaginal misoprostol every 4 hours is more effective than misoprostol alone in terminating mid-trimester gestations.


Author(s):  
Pankajkumar B. Nimbalkar ◽  
Jaldhara N. Patel ◽  
Nilesh Thakor

Background: Timely induction of labour could reduce maternal mortality and morbidity as well as assure a delivery of healthy baby. Objective of present study was to evaluate the efficacy of Misoprostol as a cervical ripening agent and its comparison with Foley’s catheter in terms of success rate, safety, side effects and patient compliance.Methods: A total of 250 pregnant women requiring induction of labor were recruited. Out of 250 cases, 150 were induced with 50 microgram Misoprostol and in 100 cases Foley catheter 18 F, was placed through the internal os of the cervix during September 2014 to August 2017 at the department of Obstetrics and Gynecology, GMERS Medical College, Dharpur-Patan. Written and informed consent was taken from the patients. Outcome measures, such as change in Bishop's score, need of augmentation, induction delivery interval; complications like hyperstimulation, fever and meconium passage were compared between two groups. Statistical analysis was performed by Epi Info 7.Results: Age range of the patients was 21 to 35 years. 72.4 % of the patients were in 21-25 years age groups. 54.4% patients were multigravida. 59.2% patients had more than 37 weeks of pregnancy. 46.4% of the patients had premature rupture of membrane as indication of labour. The mean Bishop's score for induction was 3.21 in Misoprostol group. 81.3% patients in Misoprostol group and 88% of patients in Foley’s catheter group were delivered by vaginal delivery. 60 % patients delivered within 6 hours in Misoprostol group. (Misoprostol: 60%, Foley’s catheter: 9%, p<0.001) Incidence of thin meconium was 11.3% in Misoprostol group, 9 % in Foley’s catheter group. In Misoprostol group 3.3 women had fever after induction while it was 6% in Foley’s catheter group.Conclusions: The results of the present study confirm that vaginal misoprostol is more effective than Foleys catheter in pre-induction cervical ripening.


Author(s):  
Jaydeep J. Bhatu ◽  
Disha Patel

Background: Cervical Foley’s catheter used now a days for induction of labour alone as well as a combined with cerviprim gel. The objective of the study was to assess the effectiveness of 750 cc traction on Foley catheter with no traction for labour induction in >37 weeks pregnancy.Methods: A randomized controlled trial performed on pregnant women at >37 weeks who were admitted for induction of labour with unfavourable cervix. They were randomly assigned into two groups, Foley’s with 750 cc traction and without traction. The primary outcomes were improvement in Bishop Score, number of favourable cervix following induction and the mode of delivery. The secondary outcomes were neonatal outcome, and maternal infection.Results: A total of 80 pregnant women were randomized into traction group (n=46) and non-traction group (n=34). Traction group had significantly (p=0.0462) higher number of vaginal delivery compared to non-traction group. Participants were comfortable using both methods. There was no difference in neonatal outcomes and risk of maternal infections in both groups.Conclusions: Application of traction did result in more vaginal delivery.


2018 ◽  
Vol 12 (2) ◽  
pp. 69-73
Author(s):  
Anju Mandal

Aim: The aim of this study was to compare changes in pre-induction Bishop’s Score with insertion of intra-cervical Foley catheter and vaginal Misoprostol administration for cervical ripening.Methods: It is a comparative study done among 50 patients at term that had Bishop’s score <5 in College of Medical Science in Bharatpur. Intra-cervical Foley catheter was used in half of the women and intra-vaginal insertion of 50 microgram Misoprostol tablet was used in the rest. After 24 hours of post ripening, Bishop’s score was noted and labour was induced with inj. oxytocin if required.Results: Both groups showed significant changes in the mean Bishop’s score after ripening agents, 7.64 and 7.25 for Foley catheter group and Misoprostol group respectively. Eighty four percent patients from Foley catheter group and 72% patient from Misoprostol had normal delivery.Conclusion: Post ripening mean Bishop’s score was significantly better in Foley catheter group as compared to Misoprostol group.The induction to labour interval, induction to delivery interval and labour to delivery interval were less in Foley’s catheter group than Misoprostol group.


KYAMC Journal ◽  
2021 ◽  
Vol 12 (2) ◽  
pp. 78-83
Author(s):  
Most Nasrin Nigger ◽  
Sheuly Akter ◽  
Ummul Nusrat Zahan ◽  
Fatema Begum

Background: Induction of labor is its intentional initiation before spontaneous onset, with the aim of vaginal birth which is safe for mother and newborn. The well documented effectiveness of misoprostol in several gynecological and obstetric applications has resulted in enthusiasm for its use. Objective: To see the efficacy and safety vaginal Misoprostal for cervical ripening and labour induction in late pregnancy. Materials and Methods: This single center clinical trial was carried out in the Department of Obstetrics and Gynaecology at Khwaja Yunus Ali Medical College and Hospital in Sirajgonj, Bangladesh from June 2019 to May 2020 for a period of one year. A total of 90 women requiring indicated induction of labour with an unfavourable cervix (Bishop score ≤ 4) were included in the study. They were randomly divided into two groups: 53 women induced with intravaginal misoprostol (Group I) and 37 women induced with transcervical Foley catheter (Group II). Results: Spontaneous vaginal delivery was 35(66.0%) in misoprostol group and 15(40.5%) in Foley catheter group. Caesarean section was higher in Foley catheter group than misoprostol group (37.8% vs 18.9%). The mean birth weight, APGAR score 1 minute, 5 minute, admission in neonatal intensive care unit and meconium aspiration syndrome were not statistically significant between two groups (p>0.05). Only one baby was died in Foley catheter group, but the difference was not statistically significant between two groups (p>0.05). Conclusion: The present study suggests intravaginal Misoprostol results in a shorter induction to delivery time, a reduction in the rate of caesarean delivery. KYAMC Journal.2021;12(02): 78-83


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