Study on Thyroid Dysfunction in Patients of Dysfunctional Uterine Bleeding

Thyroid Dysfunction ◽

Common Type ◽

Uterine Bleeding ◽

Thyroid Disorder ◽

Age Group ◽

Medical College ◽

Hyperthyroid Patients

Aim: The purpose of the study was to detect thyroid dysfunction in women who had abnormal uterine bleeding Study Design: Menorrhagia was the most common type of bleeding (36%). Thyroid dysfunction was discovered in 32% of the patients (Subclinical hypothyroidism in 17%, Hyper thyroid is 11% and hyperthyroidism in 4 % of cases). The researchers looked at 100 cases of Dysfunctional Uterine Bleeding that were clinically identified at Sree Balaji Medical College and Hospital between March 2014 and August 2016. The patients in this study ranged in age from under 20 to 45 years old. The number of instances with DUB who were between the ages of 31 and 40 is 38 %. Methodology: The parity of the patients ranged from unmarried to 0-5, with the parity 2 group accounting for 37% of all DUB patients and the following assessments were made. Results: Thyroid dysfunction was most common in cases of polymenorrhagia (42.8%), menorrhagia (33.3%), polymenorrhea (28.5%), and oligomenorrhea. (26%). Thyroid dysfunction was most common in the age group 31-40 years, accounting for 77.5% of the population. In 17 % of cases, the primary thyroid malfunction was subclinical hypothyroidism. 3% of hyperthyroid patients were also oligomenorrhocic. The most prevalent thyroid disorder in metrorrhagic patients was subclinical hypothyroidism.

A study of prevalence of thyroid dysfunction in abnormal uterine bleeding

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20202731 ◽

2020 ◽

Vol 9 (7) ◽

pp. 2905

Author(s):

Aditi Rai ◽

Sapna Raina

Keyword(s):

Thyroid Dysfunction ◽

Uterine Bleeding ◽

Reproductive Age ◽

Thyroid Disorders ◽

Thyroid Disorder ◽

Age Group ◽

Total N ◽

Reproductive Age Group

Background: Abnormal uterine bleeding (AUB) is one of the most frequent presentation to gynecology OPD. AUB is a common but complicated clinical presentation and occurs in 15-20% of women between menarche to menopause and significantly affects the women’s health. Thyroid disorders are more common in women than in men and cause abnormal sexual development, menstrual irregularity, infertility and premature menopause. Objective of this study was to estimate the prevalence of thyroid disorders in women in reproductive age group with AUB.Methods: A hospital based prospective cross sectional observational study was carried out in department of obstetrics and gynecology, Mazumdar-Shaw Cancer and Medical Center and Narayana Hrudayalaya Hospital at Narayana Health City, Bangalore with abnormal uterine bleeding during the period of 2 years (December 2015 to November 2017), total 153 patients were included in the study. All women with AUB in reproductive age group were included. Diagnosed cases of ovarian cyst, uterine fibroid, polyp, adenomyosis, endometriosis and malignant (endometrial and cervical) tumors were excluded. Women who are on drugs or hormone therapy (for past 3 months. IUCD users/oral contraceptives pill user. Patients with known case of thyroid disorder, carcinoma thyroid patients with history of coagulation disorder, liver disorder, renal disorder, tuberculosis.Results: A total N=115 (75.2%) of patients who took part in this study had euthyroid status. The estimated prevalence of thyroid dysfunction was 24.9%. Out of which n=22 (14.4%) had subclinical hypothyroidism, n=14 (9.2%) had overt hypothyroidism, n=2 (1.3%) had hyperthyroidism. The most common thyroid dysfunction amongst the study group was noted to be subclinical hypothyroidism (14.4%).Conclusions: There is a high prevalence of thyroid disorders in cases which are clinically diagnosed as AUB. TSH is most sensitive test in detecting thyroid dysfunction. Subclinical cases need to be treated. Hence thyroid function evaluation should be made mandatory in cases of AUB to detect thyroid dysfunction.

THE STUDY OF THYROID FUNCTION IN ABNORMAL UTERINE BLEEDING

10.36106/8132210 ◽

2021 ◽

pp. 9-10

Author(s):

Madhuri Rani ◽

Kumudini Jha ◽

Debarshi Jana

Keyword(s):

Thyroid Dysfunction ◽

Uterine Bleeding ◽

Reproductive Age ◽

Thyroid Disorders ◽

Thyroid Disorder ◽

Age Group ◽

Medical College ◽

Menstrual Irregularities ◽

Abnormal Bleeding

Background:. AUB is any abnormal uterine bleeding in the absence of any palpable pelvic pathology and demonstrable extra genital causes. AUB is responsible for 10% of gynaecological complaints.Hypothyroidism and Hyperthyroidism leads to menstrual irregularities. Females with thyroid gland abnormality have chances of reproductive abnormalities ranging from abnormal sexual development, menstrual irregularities, infertility and premature menopause.The objective of this study is to estimate the prevalence of thyroid disorders in women with abnormal uterine bleeding and to assess the menstrul pattern in women with thyroid disorder Methods: The present study was conducted in the Department of Obstetrics and Gynecology, Darbhanga Medical College and Hospital, Laheriasarai, Bihar. Total100 women of reproductive age group between 15-45 years women with abnormal bleeding were studied.Quantitative determination of T3, T4, and TSH by CLIAestimated in autoanlyser. Results: About 100 women participated in the study in which Most of the subjects belong to 26-30 years of age group(30%)followed by20-25 yrs(22%).13% in age group36-40.menorrhagia was the most common presenting symptom(66%)followed by oligomenorrhoea(21%) Thyroid disorders were prevalent in 22%.hypothyroid in 20%and hyperthyroidism in 2%.Majority had menorrhagia 66%followed by oligomenorrhea21%.among thyroid dysfunction 63.3%had menorrhagia and 36.36% had oligomenorrhea. Conclusions: So, biochemical evaluation of thyroid functioning should be made mandatory in all provisionally diagnosed cases of AUB to detect thyroid dysfunction.

EVALUATE THE RELATION BETWEEN THYROID DISORDERS AND ABNORMAL UTERINE BLEEDING IN REPRODUCTIVE AGE GROUP : A CROSS SECTIONAL STUDY AT ANMMCH, GAYA, BIHAR

10.36106/3532415 ◽

2021 ◽

pp. 15-16

Author(s):

Kumari Ragini ◽

Kumar Sourav ◽

Lata Shukla Diwedi ◽

Debarshi Jana

Keyword(s):

Thyroid Dysfunction ◽

Uterine Bleeding ◽

Reproductive Age ◽

Structural Defects ◽

Thyroid Disorders ◽

Thyroid Function Tests ◽

Age Group ◽

Reproductive Age Group

Introduction: Abnormal uterine bleeding (AUB) is a common disorder occurring in reproductive age group females. It can be understood as bleeding that occurs from the uterus outside the normal parameters and there is no structural defects in the genital tract. One of the most common association with AUB is thyroid dysfunctions. Hence this study aimed to see the incidence of thyroid related disorders in AUB and also to assess the menstrual pattern. Material and Methods: 100 women suffering from AUB who presented to OPD of Obstetrics and Gynecology department of Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar were recruited in the study. All females in 19 to 45 years of age group with abnormal uterine bleeding were included excluding those with previously known thyroid disorder, abortion history within 3 months etc. Thyroid function tests were done in all along with ultrasonography of pelvis region. Statistical analysis done. Results: The bleeding abnormality that was found in the most of the women was heavy menstrual bleeding. Women who presented with thyroid dysfunction were 33%. 23% had subclinical hypothyroidism, 6% had hypothyroidism and 4% had hyperthyroidism. Conclusion: Abnormal Uterine Bleeding has strong association with thyroid disorders. Most common type of disorder is subclinical hypothyroidism. Thus all patient of AUB must be evaluated for thyroid dysfunction

Histopathological study of endometrium in dysfunctional uterine bleeding

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20183423 ◽

2018 ◽

Vol 7 (9) ◽

pp. 3497

Author(s):

Malarvizhi Loganathan ◽

Meera Krishnakumar

Keyword(s):

Histological Change ◽

Uterine Bleeding ◽

Histopathological Study ◽

Age Group ◽

Medical College ◽

Histopathological Studies ◽

The Right ◽

Secretory Endometrium

Background: This study was undertaken to study the endometrial histology in patients presenting with abnormal uterine bleeding in the absence of palpable pelvic pathology, which helps in choosing the right modality of treatment in a particular age group with a specific histological change. The study of endometrium in dysfunctional uterine bleeding was undertaken to correlate clinical presentations with histopathological studies and to correlate the distribution of histopathological findings in various age groups.Methods: The present study was conducted in the Department of Obstetrics and Gynaecology at Govt. Dharmapuri Medical College and Hospital during the period 01.07.2017 to 31.05.2018. Patients presenting to Govt. Dharmapuri Medical College and Hospital with abnormal uterine bleeding form the material of this study. Cases have been selected by using purposive sampling technique.Results: An ovulatory cycles were more common than ovulatory cycles in all age group. However, in patients with menorrhagia and polymenorrhagia majority had secretory endometrium (ovulatory cycles).Conclusions: Majority of the patients were found in the reproduction age group with the maximum percentage in multiparous women. Menorrhagia was the commonest mode of presentation in all age group. Most of the patients with proliferative and secretory endometrium had normal sized uterus and normal looking endometrium.

A study of prevalence of thyroid disorders in patients with abnormal uterine bleeding

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20170580 ◽

2017 ◽

Vol 6 (3) ◽

pp. 1036

Author(s):

Ashok Kumar H. S. ◽

Saravanan S. ◽

Saravanan S.

Keyword(s):

Thyroid Dysfunction ◽

Uterine Bleeding ◽

Age Group ◽

Surgical Interventions ◽

Medical College ◽

Proper Management ◽

Therapeutic Procedures ◽

A Prospective Study ◽

And Function

Background: Thyroid gland is the most vital endocrine organ which plays a major role in growth, development, metabolism and function of almost every organ of our body. Both hypothyroidism and hyperthyroidism can result in menstrual irregularities. Abnormal Uterine Bleeding (AUB) is one of the most common, yet complicated clinical presentation. It occurs in 10-20% of women between 15-50 years of age. Timely detection of thyroid dysfunction in patients presenting with AUB and their proper management can prevent unnecessary surgical interventions. This study was done to analyze the prevalence of thyroid dysfunction in patients with AUB and also to look for different menstrual patterns associated with thyroid dysfunction.Methods: This is a prospective study conducted at Department of Obstetrics and Gynecology, Government Medical College, Manjeri, Kerala, India. Total 200 patients were recruited into present study after satisfying all inclusion and exclusion criteria. Complete history was taken followed by a thorough examination. Baseline investigations and T3, T4, TSH was performed in all patients. Results were analyzed.Results: As per present study, majority of the patients with AUB were from the age group of 35-49 years (43%). In patients with AUB with thyroid dysfunction, prevalence of subclinical hypothyroidism was most common followed by hypothyroidism. According to our study thyroid dysfunction was most commonly seen in the age group of 35-49 years, and the most common presentation being menorrhagia.Conclusions: Timely diagnosis and proper management of thyroid dysfunction in women with AUB can avoid variety of non-specific and ineffective diagnostic and therapeutic procedures.

Association between thyroid disorders and abnormal uterine bleeding in reproductive ages

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20203516 ◽

2020 ◽

Vol 9 (9) ◽

pp. 3580

Author(s):

Aiyleen S. Shawl ◽

Massarat Naz

Keyword(s):

Strong Association ◽

Uterine Bleeding ◽

Reproductive Age ◽

Structural Defects ◽

Thyroid Disorders ◽

Thyroid Function Tests ◽

Thyroid Disorder ◽

Age Group

Background: Abnormal uterine bleeding (AUB) means any bleeding that is not normal in amount, duration, frequency, and cyclicity. It is a common disorder occurring in reproductive age group females. It can be understood as bleeding that occurs from the uterus outside the normal parameters and there are no structural defects in the genital tract. One of the most common associations with AUB is thyroid dysfunctions. Hence, this study aimed to see the incidence of thyroid-related disorders in AUB and also to assess the menstrual pattern.Methods: A total 100 women suffering from AUB who presented to OPD of the gynecology department of L D Hospital Srinagar, Jammu and Kashmir were recruited in the study. All females in 19 to 45 years of age group with abnormal uterine bleeding were included excluding those with a previously known thyroid disorder, abortion history within 3 months, etc. Thyroid function tests were done in all along with ultrasonography of the pelvis region. Data were analyzed using SPSS software v.23.0. and Microsoft office 2007.Results: The bleeding abnormality that was found in most of the women was heavy menstrual bleeding. Out of the 100 patients taken into study 11 had thyroid disorders, out of which subclinical hypothyroidism was most prevalent accounting for 8 cases, 2 cases were found to have hypothyroidism and 1 case of hyperthyroidism was detected.Conclusions: Abnormal uterine bleeding has a strong association with thyroid disorders. The most common type of disorder is subclinical hypothyroidism. Thus, all patient of AUB must be evaluated for thyroid dysfunction.

A study of thyroid dysfunction in dysfunctional uterine bleeding

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20171972 ◽

2017 ◽

Vol 6 (5) ◽

pp. 2035 ◽

Cited By ~ 1

Author(s):

Santosh Kumar Verma ◽

Anita Pal ◽

Saroj Jaswal

Keyword(s):

Thyroid Dysfunction ◽

Uterine Bleeding ◽

Endometrial Pattern ◽

Proliferative Endometrium ◽

Biochemical Evaluation ◽

Hypothyroid Patients ◽

Hyperthyroid Patients ◽

Secretory Endometrium

Background: The objective of the study was to evaluate the prevalence of thyroid dysfunction in dysfunctional uterine bleeding and to assess the menstrual and endometrial pattern in women with thyroid disorders.Methods: The present study was conducted on 200 patients who presented with dysfunctional uterine bleeding in gynecology OPD.Results: Among the 200 women 39 (19.5%) had hypothyroidism, 2 (1%) had hyperthyroidism and 159 (79.55%) were euthyroid. Menorrhagia was the most common menstrual disorder in hypothyroidism and oligomenorrhoea in hyperthyroidism. In the present study 74.3% patients had proliferative endometrium,26.3% secretory endometrium, in hypothyroid patients and secretory endometrium in 2 (1%) hyperthyroid patients. A woman with hypothyroidism, commonly presents with anovulation and unopposed oestrogen activity causes endometrial hyperplasia which may outgrow the blood supply and may cause local areas of necrosis and breakdown and produces bleeding.Conclusions: The menstrual irregularities are significantly more frequent in patients with thyroid dysfunction and menorrhagia was the commonest menstrual abnormality. The study concludes that biochemical evaluation of thyroid function should be made mandatory in all cases of abnormal uterine bleeding and this would avoid unnecessary surgeries and exposure to hormones.

A STUDY OF ASSOCIATION OF THYROID DISORDERS IN PATIENTS WITH ABNORMAL UTERINE BLEEDING

10.36106/ijsr/8331245 ◽

2021 ◽

pp. 1-2

Author(s):

MD Nurejjaman ◽

Anuradha Ghosh ◽

Shermin Siria Begum ◽

Debarshi Jana

Keyword(s):

Thyroid Dysfunction ◽

Hormonal Treatment ◽

Uterine Bleeding ◽

Reproductive Age ◽

Thyroid Disorders ◽

Thyroid Disorder ◽

Age Group ◽

Unnecessary Intervention ◽

Menstrual Disturbances

Introduction: The aim of the study was to determine the association between menstrual disturbances and thyroid dysfunction, to analyze the pattern of menstrual dysfunctions among women with thyroid disorder and to estimate the prevalence of subclinical thyroid diseases among women in the reproductive age group with abnormal uterine bleeding, Materials And Methods: This was an observational study conducted in the department of Obstetrics and Gynaecology, Institute of Post Graduate Medical Education & Research, SSKM Hospital, Kolkata from March 2019 to August 2020. Inclusion criteria were patients attending OPD with age group of 18-45 years, women with any of the following menstrual disturbances- menorrhagia, oligomenorrhoea, hypomenorrhea, polymenorrhoea, amenorrhoea with no pelvic pathology and USG showing normal uterus and ovaries. Conclusion: From our study, it may be concluded that there is a strong correlation of thyroid dysfunction with abnormal uterine bleeding. In the patients with abnormal uterine bleeding, if thyroid disorders are timely diagnosed and treated, the menstrual irregularities settle, and unnecessary intervention like hormonal treatment and surgery like hysterectomy can be avoided. Since thyroid dysfunction is an important treatable cause of abnormal uterine bleeding, estimation of thyroid status should be a part of the battery of investigations being done in the patients of abnormal uterine bleeding.

A study of thyroid dysfunction in dysfunctional uterine bleeding

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20180881 ◽

2018 ◽

Vol 7 (3) ◽

pp. 1002 ◽

Cited By ~ 1

Author(s):

Sujata Singh ◽

Shradhanjali Sahoo ◽

Pravat Chandra Das

Keyword(s):

Thyroid Dysfunction ◽

Uterine Bleeding ◽

Aetiological Factor ◽

Obstetrics And Gynecology ◽

Thyroid Disorder ◽

Age Group ◽

Menstrual Disorder ◽

Menstrual Irregularities ◽

Menstrual Pattern

Background: The objective of the study was to evaluate the prevalence of thyroid disorder in dysfunctional uterine bleeding and to assess the menstrual pattern in women with thyroid disorders.Methods: The present study was conducted on 104 patients who presented with dysfunctional uterine bleeding in gynecology OPD/IPD Department of Obstetrics and Gynecology, SCBMCH, Cuttack, India.Results: Among the 104 women 16 (15.3%) had hypothyroidism, 3 (2.8%) had hyperthyroidism and 75 (72.1%) were euthyroid and 10(9.6%) subclinical hypothyroidisim. Menorrhagia was the most common menstrual disorder in hypothyroidism and oligomenorrhoea in hyperthyroidism. In the present study the age group of 41-50 year and multyparity (para-2) and commonest are menorrhagic 42 (40.38%). Menorrhagia in hypothyroidisim 15 (72.4%) cases and oligomenorrhoea in hyperthyroidisim 3 (10.3%).Conclusions: Thyroid dysfunction should be considered as an important aetiological factor in menstrual disturbances and thyroid assessment should be done in all patients with menstrual irregularities. Therefore, to conclude any type of menstrual abnormality should be considered as a possible presenting symptom of thyroid dysfunction and it may even indicate subclinical abnormality, evaluation of thyroid would avoid unnecessary surgeries and exposure to hormones.

ETIOLOGY OF PUBERTY MENORRHAGIA - A PROSPECTIVE STUDY

10.36106/paripex/3000861 ◽

2019 ◽

pp. 1-2

Author(s):

Dr Jananii

Keyword(s):

Early Stage ◽

Uterine Bleeding ◽

Thyroid Disorder ◽

Age Group ◽

Bleeding Diathesis ◽

Duration Of Symptoms ◽

Medical College ◽

Chief Complaints ◽

A Prospective Study

OBJECTIVES: To determine the etiology of puberty menorrhagia. MATERIALS AND METHOD:A total of 35 cases who attended OBG OPD at Shri SathyaSai Medical college from January 2019 – June 2019 who presented with chief complaints of irregular heavy menstrual bleeding since menarche were included in this study.After taking detailed history taking,physical examination,lab investigations,ultrasound etiology of puberty menorrhagia is ruled out. RESULTS: Most common age group in our study are between 12 – 14 years (60%).34.2 % attained menarche between 12 – 13yrs.Around 27 patient had duration of symptoms for less than 6 months, 6 had symptoms for about 6 – 12 months, 2 had for more than 1 year. Most common etiolgy in our study is PCOD (25.7%), anovulatory without PCOD (20 %), bleeding diathesis and thyroid disorder (17.1 %), pregnancy complication (8.5%), tuberculosis (5.7 %), fibroid and endometriosis (2.8 %). CONCLUSION: Puberty menorrhagia needs to be evaluated in early stage rather than at later stage so that consequences of abnormal uterine bleeding can prevented.