Clinicopathological study of testicular tumors: an experience in a tertiary care hospital in Kashmir valley, Jammu and Kashmir, India

Background: Testicular and paratesticular neoplasia are rare type of tumors affecting adolescents and young adults in India, as observed by paucity of published data. This study was undertaken to analyze the patterns of testicular tumors at a tertiary level hospital in Kashmir valley, Jammu and Kashmir, India highlighting the patient’s demography, clinical presentation, diagnostic evaluation and pathological finding.Methods: This 5-year (retrospective and prospective) study was performed in the Department of Pathology, Government Medical College Srinagar, Jammu and Kashmir, India from January 2012 to December 2016. For the retrospective study, all cases of testicular tumors, their histopathological reports and required clinical details were searched from records maintained in the Department of Pathology, GMC Srinagar, Jammu and Kashmir, India. For the prospective study, the orchiedectomy specimens received in our department were subjected to routine histopathological processing followed by a detailed gross and microscopic examination. Tumour typing and subtyping was done according to WHO classification (2004).Results: A total of 37 cases of testicular and paratesticular neoplasia were included in present study with a mean age of 35.1 years. Out of these 37 cases, 31 (83.78%) were malignant and 6 cases (16.22%) were benign. Right testis was affected in 70.3% of cases. The most common clinical presentation was scrotal swelling. Germ cell tumor was the most common type accounting for 89.2% of tumors followed by lymphomas (8.1%).Conclusions:It is concluded that despite new techniques in imaging and tumor marker assay, the diagnosis of testicular tumors is dependent upon histopathological examination. The present study fairly provides an insight into the clinical presentations, prevalence and patterns of testicular tumors.

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Allergic Fungal Rhinosinusitis: A Study in a Tertiary Care Hospital in India

Journal of Allergy ◽

10.1155/2016/7698173 ◽

2016 ◽

Vol 2016 ◽

pp. 1-6 ◽

Cited By ~ 1

Author(s):

Ravinder Kaur ◽

S. Lavanya ◽

Nita Khurana ◽

Achal Gulati ◽

Megh S. Dhakad

Keyword(s):

Clinical Presentation ◽

Histopathological Examination ◽

Tertiary Care ◽

Clinical Samples ◽

Nasal Discharge ◽

Care Hospital ◽

Deviated Nasal Septum ◽

Direct Microscopy ◽

Fungal Rhinosinusitis ◽

Allergic Fungal Rhinosinusitis

The study was conducted to study the occurrence and clinical presentation of allergic fungal rhinosinusitis (AFRS), characterize the same, and correlate with the microbiological profile. Clinically suspected cases of fungal rhinosinusitis (FRS) depending upon their clinical presentation, nasal endoscopy, and radiological evidences were included. Relevant clinical samples were collected and subjected to direct microscopy and culture and histopathological examination. 35 patients were diagnosed to have AFRS. The average age was 28.4 years with a range of 18–48 years. Allergic mucin was seen in all the AFRS patients but fungal hyphae were detected in only 20%. 80% of cases were positive for IgE. All the patients had nasal obstruction followed by nasal discharge (62.8%). Polyps were seen in 95% (unilateral (48.57%) and bilateral (45.71%)), deviated nasal septum was seen in 28.57%, and greenish yellow secretion was seen in 17.14%. Direct microscopy and septate hyphae were positive in 71.42% of cases. 91.4% of cases were positive by culture. 5.7% yielded mixed growth of A. flavus and A. niger. Prompt clinical suspicion with specific signs and symptoms along with timely sampling of the adequate patient specimens and the optimal and timely processing by microscopy and culture and histopathological examination is a must for early diagnosis and management.

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Enigma in the diagnosis of congenital neck masses: a prospective study

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20195708 ◽

2019 ◽

Vol 6 (1) ◽

pp. 159

Author(s):

Rajesh Radhakrishna Havaldar ◽

Anju Singh ◽

Priti S. Hajare ◽

Shama A. Bellad ◽

R. S. Mudhol

Keyword(s):

Prospective Study ◽

Bronchogenic Cyst ◽

Histopathological Examination ◽

Tertiary Care ◽

Needle Aspiration ◽

Neck Mass ◽

Care Hospital ◽

Duct Cyst ◽

Neck Masses ◽

A Prospective Study

Background: Head and neck swellings are common in routine otorhinolaryngologic practice. This study was done to assess the incidence and varied presentation of different congenital neck swellings.Methods: Hospital based prospective study done in the Department of Otorhinolaryngology at a tertiary care hospital from January 2017 to December 2018. A total of 28 patients with slow, progressive neck swellings were selected after excluding thyroid swellings and acute inflammatory neck swellings. All patients had no other complaints. After a thorough clinical examination and investigations like ultrasonography, fine needle aspiration cytology and radiological examination, surgery was done, and specimens obtained were sent for histopathological examination. Patients were followed up to 1 year. Results: 28 patients with congenital neck mass were studied. 15 were thyroglossal cysts, 7 were branchial anomalies, 5 were dermoid cysts and 1 was bronchogenic cyst. The most frequent congenital neck mass was thyroglossal duct cyst and fistula (53.57%) followed by, in descending order, cysts and fistulas of the branchial apparatus (25%), dermoid cysts (17.85%) and bronchogenic cyst (3.5%) respectively.Conclusions: The overall presentation in terms of age group, location, incidence and clinical features of congenital neck swellings is an enigma to the treating surgeon as well as the pathologist. The prevalence varies largely among centres. A knowledge of the varied differential diagnosis of slow progressive masses in the neck should be kept in mind while planning the surgical procedure for total removal of the lesion to avoid recurrence.

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A prospective study to analyze the etiology, prevalence, clinical presentation, age and sex wise distribution of thyrotoxicosis among thyroid disorders in a tertiary care hospital

International Surgery Journal ◽

10.18203/2349-2902.isj20203777 ◽

2020 ◽

Vol 7 (9) ◽

pp. 2965

Author(s):

Manoj Kumar Nirmalanandan ◽

Kavitha Jayanthi Balachandran

Keyword(s):

Early Diagnosis ◽

Prospective Study ◽

Clinical Presentation ◽

Tertiary Care ◽

Clinical Syndrome ◽

Thyroid Disorders ◽

Care Hospital ◽

Medical College ◽

A Prospective Study ◽

Age And Sex

Background: Thyrotoxicosis is a clinical syndrome characterized by an excess of free thyroxine and triiodothyronine or both. One of the major and usual causes of thyrotoxicosis is Graves’ disease. Morbidity associated with the situation is very high and it demands early diagnosis and treatment. This can reduce the burden of the disease it imparts on the society. The aim of the study is to analyse the etiology, prevalence, clinical presentation, age, and sex-wise distribution of thyrotoxicosis among thyroid disorders presenting to Government Medical College, Thiruvananthapuram.Methods: It is a prospective study undertaken in tertiary care and teaching hospital over a period of one year. 2401 patients admitted in the general ward with thyroid disorders were included in the study. Definite inclusion and exclusion criteria were followed. Relevant blood tests were done in all cases.Results: On analysis of the data which were entered in excel format the prevalence of thyrotoxicosis was 2.5%. The majority of the study population was in the twenties and forties. Incidences in females were more mainly due to increased prevalence.Conclusions: By studying the etiology, prevalence, clinical presentation, age, and sex-wise distribution of Thyrotoxicosis, the disease burden in the population can be understood and early diagnosis and proper treatment can be instituted. Our study prevalence was comparable with similar studies done in other institutions.

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Prospective study of skin adnexal tumours for a period of two years in a tertiary care hospital

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20175724 ◽

2017 ◽

Vol 6 (1) ◽

pp. 225

Author(s):

Sridevi Sanapala ◽

Jagadeeswari Suvvari ◽

Satish K. Seeram ◽

Mounika Kondapalli ◽

Suresh Masa ◽

...

Keyword(s):

Prospective Study ◽

Histopathological Examination ◽

Correct Diagnosis ◽

Tertiary Care ◽

Clinical History ◽

Care Hospital ◽

Malignant Tumours ◽

Rare Tumours ◽

King George Hospital ◽

Hematoxylin And Eosin Stain

Background: Skin adnexal tumours are rare tumours with complex histological patterns and variations and difficult to diagnose by histopathology only, so clinical history and presentation is necessary. The objective of the study was to correlate with age, sex, location, type of differentiation of adnexal tumours in our pathology department.Methods: The present study was a prospective study done in the department of pathology in Andhra medical college, King George Hospital, Visakhapatnam. A total of 51 cases were included in this study from January 2015 to December 2016. Specimens were formalin fixed and after adequately processing the sections were stained routinely with hematoxylin and eosin stain and properly evaluated for histopathological examination.Results: Out of these 51 cases, 88.24% (45 cases) were benign, and 11.76% (6 cases) were malignant tumours. Hair follicle differentiation were most common (35.3%) followed by sebaceous gland differentiation (31.37%) and sweat gland differentiation (29.41%).Conclusions: Benign adnexal tumours were most common than malignant tumours. Skin adnexal tumours are clinically often misdiagnosed, so histopathological examination remains gold standard for their correct diagnosis.

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A PROSPECTIVE STUDY TO ASSESS THE DIAGNOSTIC EFFICACY OF LABORATORY RISK INDICATOR FOR NECROTIZING FASCIITIS (LRINEC) SCORING SYSTEM IN PATIENTS WITH SOFT TISSUE INFECTION

10.36106/gjra/5206015 ◽

2020 ◽

pp. 37-39

Author(s):

K. Vani ◽

Gattupalli Bhaswanth Kumar Reddy ◽

B. Jayakiran ◽

J. Ramanaiah ◽

B. Balaji ◽

...

Keyword(s):

Soft Tissue ◽

Prospective Study ◽

Necrotizing Fasciitis ◽

Soft Tissue Infection ◽

Histopathological Examination ◽

Tertiary Care ◽

Tissue Infection ◽

Risk Indicator ◽

Care Hospital ◽

A Prospective Study

Background Necrotizing fasciitis which is commonly known as “Flesh-Eating Disease” is an uncommon soft-tissue infection. It is characterized by widespread fascial necrosis with relative sparing of overlying skin and underlying muscle. Mostly it is associated with severe systemic toxicity and a fulminant course. It is usually rapidly fatal unless promptly recognized and aggressively treated with appropriate antimicrobials and surgical debridement at the earliest. Methods Our study was a prospective study conducted on 140 patients over a period of 2 years from June 2018 to June 2020 in a tertiary care hospital, GGH, Kadapa. All patients were selected randomly and evaluated by taking proper history, thorough clinical examination, routine laboratory investigations and histopathological examination of the debrided tissue and the outcomes were analysed to know the efficacy of LRINEC Scoring in diagonising necrotizing fasciitis. Results Most common age group was 41-50 years. Males were commonly affected, accounting to 74% i.e., 111 patients and the remaining 39 patients were females (39%). Fever, inflammation of the involved area were the most common presentations. Majority were diabetic and hypertensive accounting to 55.3% and 52.7% respectively. All patients presented with symptoms with swelling, redness, pain and induration. Eighty-one percent had elevated CRP. Total WBC count was raised in 78.7% of the cases. Fifty-six percent of the cases had haemoglobin less than 11g/dl. Hyponatremia was observed in 81.3% of the patients. Majority (52.7%) had normal sr. creatinine i.e., < or =1.4. RBS was elevated in 54.7% of the cases. In our study 87.3% of the patients had a LRINEC score >6. Histology was positive for necrotising fasciitis in 92% of the cases, among them majority had polymicrobial organisms on culture. Conclusion In patients with severe soft tissue infections, LRINEC scoring based on laboratory parameters is an easy and reliable diagnostic tool to diagnose Necrotizing fasciitis accurately.

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Clinicopathological Profile of Sino-nasal Masses at a Tertiary Care Hospital: A Descriptive Study

Bengal Journal of Otolaryngology and Head Neck Surgery ◽

10.47210/bjohns.2021.v29i2.470 ◽

2021 ◽

Vol 29 (2) ◽

pp. 133-139

Author(s):

Nitin Deosthale ◽

Priyal Patil ◽

Sonali Khadakkar ◽

Pavani Garikapati ◽

Kanchan Dhote ◽

...

Keyword(s):

Clinical Presentation ◽

Tertiary Care Hospital ◽

Histopathological Examination ◽

Tertiary Care ◽

Descriptive Study ◽

Careful Examination ◽

Care Hospital ◽

Male Predominance ◽

Neoplastic Lesion ◽

Number Of Patients

Introduction The Sino-nasal mass is a common clinical entity. Although it has varied aetiology ranging from non-neoplastic to neoplastic, clinical presentation is overlapping that poses diagnostic dilemma. Objective of the study was to study the clinical profile of Sino-nasal masses in terms of demographic profile, clinical presentation and clinicopathological diagnosis. Materials and Methods A descriptive study was carried out at tertiary care hospital for 2 years. Clinically diagnosed cases of sino-nasal masses were included in the study. Previously treated cases, congenital lesions were excluded. Provisional diagnosis was made based on clinical and radiological evaluation. Diagnosis on histopathological examination was considered as definitive. Results Total of 75 patients were included in the study. Demographic data showed slight male predominance (M:F= 1.08:1), with most patients from age group 31-40 years (26.67%). Nasal obstruction was the most common presenting symptom. The number of patients with non-neoplastic lesion was 48; 17 patients had neoplastic benign lesions while 6 patients had neoplastic malignant lesions. Conclusion Large number of patients presents with trivial symptoms but need careful examination and appropriate diagnosis. Inflammatory lesions outnumbered neoplastic lesions in our study. Clinical suspicion and appropriate investigations can guide in timely intervention and management of these patients reducing the morbidity and mortality in these patients.

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