scholarly journals Saline dressing versus povidone iodine dressing in chronic diabetic foot ulcer healing: a prospective comparative study

2019 ◽  
Vol 6 (5) ◽  
pp. 1524
Author(s):  
Srinivas B. Kulkarni ◽  
Venkatesh S. ◽  
Kruthi S. R.
Keyword(s):  
Comparative Study ◽  
Surface Area ◽  
Diabetic Foot ◽  
Povidone Iodine ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Daily Basis ◽  
Complete Healing ◽  
Prospective Comparative Study ◽  
The Mean

Background: Numerous topical agents are used for chronic diabetic foot ulcer (DFU) care and healing. In most of the hospitals in India povidone iodine is used topically for DFU dressing, however few other agents are more efficacious; the present study was aimed to compare the effect of povidone iodine and normal saline dressing in healing of DFU.Methods: A total of 50 patients (25 patients in each arm of povidone Iodine and Saline dressing group) with complaints of chronic DFU attending surgery outpatient department of Rajarajeswari Medical College and Hospital were considered in this prospective comparative study from July 2017 to December 2018. Dressings were done on daily basis for a period of 6 weeks, and the results were compared on 2nd, 4th and 6th week, using reduction in surface area of chronic DFU as parameter of healing process.Results: The mean surface area of wound in povidone iodine group was: baseline- 12.2 sq.cm, 2nd week- 11.7 sq.cm, 4th week- 10.6 sq.cm, 6th week- 9.8 sq.cm; While in saline group was: baseline- 13.3 sq.cm, 2nd week- 11.6 sq.cm, 4th week- 10.8 sq.cm, 6th week- 9.6 sq.cm. After 6 weeks, the mean reduction in surface area of wound is more in the saline dressing group compared with the povidone iodine dressing group and the results are statistically significant at a p<0.05.Conclusions: Saline dressing is more effective than povidone iodine dressing in achieving complete healing, reducing wound surface area, and increasing comfort in subjects with chronic DFU.

scholarly journals Comparison of Efficacy of Alginate Filler Dressings with Conventional Saline Dressings for Cavity Wounds in Diabetic Foot Ulcer- A Prospective Cohort Study

2020 ◽  
Author(s):  
Tharun Ganapathy Chitrambalam ◽  
Pradeep Joshua Christopher ◽  
Jeyakumar Sundaraj ◽  
Ramyasree Paladugu ◽  
Sundeep Selvamuthukumaran
Keyword(s):  
Cohort Study ◽  
Surface Area ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Saline Group ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
The Mean ◽  
Culture Positive

Introduction: Diabetic foot ulcers are associated with 25% of patients with Diabetes Mellitus (DM). These diabetic foot ulcers if not given appropriate care at the right time can lead to amputations and poor quality of life. Alginate dressings are newer and help in faster healing of cavity wounds in diabetic foot ulcer. Aim: To compare the advantages of alginate dressings over conventional saline dressings in cavity wounds of diabetic foot ulcer patients. Materials and Methods: A single centre prospective longitudinal cohort study was conducted on 88 patients with diabetic foot ulcers randomising equally into two groups containing 44 patients in each group in a tertiary care hospital. The wounds of all patients included in the study were thoroughly debrided and initial assessment was done using the Pressure Ulcer Scale for Healing (PUSH) scoring system. The patients were started on alginate dressings in one group and saline dressings in other group and were assessed after two and four weeks. The reduction in the surface area of the wound, reduction in the exudate amount, type of the tissue over the ulcer and reduction in the bacterial load (wound cultures) of the ulcers were studied. The statistical analysis were done using Statistical Package for the Social Sciences (SPSS) software version 21. The statistics were done using independent sample tests (Levene’s test for equality of variances and t-test for equality of means), Mann-Whitney test and Wilcoxon test. Results: The results of wound assessment before dressings, at two weeks and at the end of four weeks are as follows: The mean (SD) reduction in wound surface area was 9.07 (1.634) to 6.89 (1.434) to 4.68 (1.272) for alginate group and 9.25 (2.059) to 8.00 (1.905) to 6.50 (1.650) for saline group. The mean (SD) reduction of the exudate amount was 2.02 (0.505) to 1.09 (0.473) to 0.14 (0.347) for alginate group and 1.98 (0.590) to 1.43 (0.625) to 0.75 (0.615) for the saline group. The mean (SD) for tissue type of cavity wounds assessed via PUSH scoring was reduced from 2.30 (0.701) to 0.16 (0.370) for the alginate group in comparison to 2.32 (0.740) to 0.77 (0.743) for the saline group at the end of four weeks. On evaluation of the wound cultures; 6 out of 44 patients (13.6%) were culture positive in the alginate group while 30 out of 44 patients (68.2%) were culture positive from the saline group at the end of four weeks. All the above results were statistically significant with a p-value of 0.001. Conclusion: Alginates dressings are superior to saline dressings in terms of reduction in the size of the ulcer and control of microbial activity in diabetic foot. Alginate absorbs large amount of exudates and fill in irregular shaped cavities which are ideal in treating cavity wounds in diabetic foot syndrome.

scholarly journals Collagen Based vs Conventional Dressing in the Treatment of Diabetic Foot Ulcer—A Comparative Study

2021 ◽  
Vol 13 (13) ◽  
pp. 108-113
Author(s):  
Mishra T ◽  
Mishra J ◽  
Panigrahy R ◽  
Baral P ◽  
Patra GT ◽  
...  
Keyword(s):  
Comparative Study ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer

scholarly journals Prevalence of diabetic complications and risk factors among diabetic foot ulcer patients: a retrospective hospital-based study

2018 ◽  
Vol 5 (11) ◽  
pp. 3608
Author(s):  
Shanmuga Raju P. ◽  
Venkata Ramana N. ◽  
Surya Narayana Reddy V. ◽  
Bhagya Seela S. ◽  
Sachin G.
Keyword(s):  
Risk Factors ◽  
Health Care ◽  
Blood Sugar ◽  
Diabetic Foot ◽  
Tertiary Care ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Diabetic Patients ◽  
Care Hospital ◽  
The Mean

Background: Diabetic foot ulcer is a painful, demands increased health care utilization, and increases healthcare costs for the patients as well as the health care system. The purpose of this study was to analysis the prevalence of diabetic foot complications and risk factors among diabetic patients at tertiary care Hospital, Karimnagar.Methods: Total 60 sample sizes were included in the study. The study was conducted at General Surgery ward, Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar from July 2017 to June 2018. Demographic, complications and risk factors were recorded, and outcomes were analyzed using SPSS statistics version 21.0.Results: The Mean age of the study group is 50.31±14.26 years. The male to female distribution is 47 (78.3%) and 13 (21.7%) respectively. The mean duration of illness in days is 96.68±289.21, while mean HbA1C is 9.44±9.02. The mean fasting blood sugar and postprandial blood sugar is 159.78±70.01 and 157.78±86.28 which shown no significance difference (p = 0.87). Odds ratio with 95% confidence interval was computed to the level of significant.Conclusions: There was no significant outcome was found in diabetic foot ulcer. Patient with high risk complications need as early detection, foot care education, moderate physical, exercise, fitted foot wear and diabetic diet should be decrease the risk of diabetic foot ulcers.

Management of diabetic foot ulcer: A comparative study between pentoxifylline and traditional therapy

2019 ◽  
Vol 9 (2) ◽  
pp. 63-66
Author(s):  
Sandip Singh Mavi ◽  
◽  
Paritoshsingh B Thakur ◽  
T Ramachandrudu ◽  
◽  
...  
Keyword(s):  
Comparative Study ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Traditional Therapy

When acral malignant melanoma facades as diabetic foot!

2021 ◽  
Vol 14 (7) ◽  
pp. e242918
Author(s):  
Zainab Akram Yousif Yasear ◽  
Lynda Bloomer ◽  
Roshan Siddique ◽  
Haroon Siddique
Keyword(s):  
Diabetic Foot ◽  
Standard Treatment ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Initial Response ◽  
Final Diagnosis ◽  
Complete Healing ◽  
Acral Lentiginous Melanoma ◽  
Black Spots ◽  
Initial Intervention

An 85-year-old Indian man presented with non-healing foot ulcer over the left heel. There was initial response to wound size with standard treatment including offloading, debridement and antibiotic therapy. However, subsequently, there was no progress noted. Incidentally, two small black spots in the wound bed raised the suspicion of melanoma. Incisional biopsy confirmed acral lentiginous melanoma (ALM). The final diagnosis was ALM coexisting with diabetic foot ulcer (DFU). The wound was treated by surgical resection and flap reconstruction that resulted in complete healing. Fourteen months after the initial intervention, the patient developed a new lump and ulceration around the previous wound bed. This turned out to be recurrent disease with distant metastasis. The patient died eventually with palliative support. Through this case, we would like to highlight the importance of early biopsy and intervention in DFU especially for those wounds with atypical presentation or refractory to standard treatment.

Cardiac Autonomic Neuropathy is Associated with Improved Diabetic Foot Ulcer Healing: A Single Centre Prospective Cohort Study

2020 ◽  
Author(s):  
Frederick Farrow ◽  
Nikolaos Fountoulakis ◽  
Kelly Cummins ◽  
Angelica Sharma ◽  
Rabiah Mahmood ◽  
...  
Keyword(s):  
Cohort Study ◽  
Autonomic Neuropathy ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Major Amputation ◽  
Complete Healing ◽  
University Hospital ◽  
Cardiac Autonomic Neuropathy ◽  
Single Centre

Abstract Aims People with diabetes and peripheral neuropathy (DPN) are at high risk of diabetic foot ulceration (DFU). The prevalence of cardiac autonomic neuropathy (CAN) in people with DFU is unknown and if CAN influences DFU healing is unclear. Methods We investigated, in a prospective observational single-centre cohort study, if CAN predicts DFU healing in 47 (77% male) people with a DFU and DPN attending a university hospital foot clinic. CAN was diagnosed by 2 or more abnormal Ewing’s tests. Baseline DFU severity was evaluated using the site, ischaemia, neuropathy, bacterial infection, area and depth (SINBAD) score. The primary outcome was defined as evidence of DFU healing on clinical examination. Median (interquartile) length of follow-up was 1150 (624–1331) days. Results The prevalence of CAN was 43%. Of the cohort, 70% had complete healing of their DFU. Participants with CAN had a shorter median (interquartile) duration time to heal compared to those without CAN [91 (44–164) days compared to 302 (135–413) (p=0.047)]. Minor/major amputation and mortality was similar in both groups. The presence of CAN increased DFU healing by two-fold [HR=2.05, 95% CI 1.01–4.16, p=0.046] in multivariable competing risk analyses. Conclusions We demonstrate a high prevalence of CAN in a DFU cohort and that CAN is associated with improved DFU healing. The results of this study establish the scientific rationale for further studies to better understand the mechanisms between CAN and DFU outcomes.

scholarly journals Efficacy of a povidone‐iodine foam dressing (Betafoam) on diabetic foot ulcer

2019 ◽  
Vol 17 (1) ◽  
pp. 91-99 ◽  
Author(s):  
Heui C. Gwak ◽  
Seung H. Han ◽  
Jinwoo Lee ◽  
Sejin Park ◽  
Ki‐Sun Sung ◽  
...  
Keyword(s):  
Diabetic Foot ◽  
Povidone Iodine ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer
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