scholarly journals A comprehensive study of clinical features and management of ulcers of the lower limb

2019 ◽  
Vol 6 (11) ◽  
pp. 4024
Author(s):  
Pradip Kumar Mohanta ◽  
Chinmoy Mallik ◽  
Suman Kumar Chatterjee

Background: Leg ulcers are debilitating and painful, greatly reducing patient’s quality of life. These ulcers are often difficult to treat and the successful treatment of leg ulcers depends upon the accurate diagnosis and treatment of the underlying cause.Methods: This prospective cross sectional study was conducted by Department of General Surgery at College of Medicine and JNM Hospital, Nadia. The study was conducted during the period from September 2017 to August 2019 which included 193 patients presenting with ulcers of the lower limb and admitted in surgical wards of our hospital.Results: Most of the patients were engaged in agriculture (23.8%) followed by business (22.8%) and service (14.5%). 52.03% of the patients had habit of smoking, chewing tobacco and drinking of alcohol. Most of the ulcers were diabetic (36.3%) followed by venous (22.3%) (Z=2.17; p=0). Only 4.7% and 3.1% were malignant and trophic ulcers. Peripheral neuropathy (23.3%) was the most common type of ulcer followed by venous hypertension (22.3%). At the end of study period, 180 ulcers were healed, 3 had recurrence, 5 were disease free and 5 patients died.Conclusions: Thus, the study of various cases of leg ulcers arouses lot of interest and is mind boggling as far as the treatment of these cases are concerned. With the availability of arsenal of investigation wide range of antibiotics and with ever improving dressing material, there is certainly a great improvement in treatment of chronic leg ulcers.

Symmetry ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 598
Author(s):  
Massimiliano Pau ◽  
Bruno Leban ◽  
Michela Deidda ◽  
Federica Putzolu ◽  
Micaela Porta ◽  
...  

The majority of people with Multiple Sclerosis (pwMS), report lower limb motor dysfunctions, which may relevantly affect postural control, gait and a wide range of activities of daily living. While it is quite common to observe a different impact of the disease on the two limbs (i.e., one of them is more affected), less clear are the effects of such asymmetry on gait performance. The present retrospective cross-sectional study aimed to characterize the magnitude of interlimb asymmetry in pwMS, particularly as regards the joint kinematics, using parameters derived from angle-angle diagrams. To this end, we analyzed gait patterns of 101 pwMS (55 women, 46 men, mean age 46.3, average Expanded Disability Status Scale (EDSS) score 3.5, range 1–6.5) and 81 unaffected individuals age- and sex-matched who underwent 3D computerized gait analysis carried out using an eight-camera motion capture system. Spatio-temporal parameters and kinematics in the sagittal plane at hip, knee and ankle joints were considered for the analysis. The angular trends of left and right sides were processed to build synchronized angle–angle diagrams (cyclograms) for each joint, and symmetry was assessed by computing several geometrical features such as area, orientation and Trend Symmetry. Based on cyclogram orientation and Trend Symmetry, the results show that pwMS exhibit significantly greater asymmetry in all three joints with respect to unaffected individuals. In particular, orientation values were as follows: 5.1 of pwMS vs. 1.6 of unaffected individuals at hip joint, 7.0 vs. 1.5 at knee and 6.4 vs. 3.0 at ankle (p < 0.001 in all cases), while for Trend Symmetry we obtained at hip 1.7 of pwMS vs. 0.3 of unaffected individuals, 4.2 vs. 0.5 at knee and 8.5 vs. 1.5 at ankle (p < 0.001 in all cases). Moreover, the same parameters were sensitive enough to discriminate individuals of different disability levels. With few exceptions, all the calculated symmetry parameters were found significantly correlated with the main spatio-temporal parameters of gait and the EDSS score. In particular, large correlations were detected between Trend Symmetry and gait speed (with rho values in the range of –0.58 to –0.63 depending on the considered joint, p < 0.001) and between Trend Symmetry and EDSS score (rho = 0.62 to 0.69, p < 0.001). Such results suggest not only that MS is associated with significantly marked interlimb asymmetry during gait but also that such asymmetry worsens as the disease progresses and that it has a relevant impact on gait performances.


Author(s):  
Carmen Folguera-Álvarez ◽  
Sofia Garrido-Elustondo ◽  
Milagros Rico-Blázquez ◽  
José Verdú-Soriano

The presence of venous leg ulcers (VLU) is associated with emotional disorders in individuals who have conditions, such as depression, anxiety, and sleeping problems, which result in a reduced perceived quality of life by these individuals. The study aim was to describe the perceived quality of life and associated factors for individuals with VLU. We conducted a cross-sectional study in 22 primary care health centers with a sample of 93 individuals with VLU. The variables collected were the following: perceived quality of life measured with Spanish version of the Charing Cross Venous Ulcer Questionnaire (CCVUQ-e), ulcer severity measured with the RESVECH 2.0 Score, demographic variables, and those related to the healing process. The results showed a mean CCVUQ-e score of 47.4 ± 11.8 points (Mean ± SD), with the most affected dimension being the emotional status, followed by cosmesis, social interaction, and domestic activities. The mean RESVECH 2.0 score was 11.1 ± 3.7 points. An association was found between ulcer-related pain and poorer quality of life ( P < .05, t test) and between erythema in perilesional skin and poorer quality life ( P < .05, t test). The signs of infection and inflammation in the VLUs were as follows: increasing exudate, friable tissue, and biofilm-compatible tissue, which were associated with a poorer quality of life ( P < .05, t test). The multivariate model was statistically significant and explained a variability of 26% in the CCVUQ-e score. This study confirms that wound severity, pain, and signs of infection in VLU decrease the perceived quality of life of individuals with these wounds.


Author(s):  
Qian Wang ◽  
Caiyun Chen ◽  
Sheng Zhang ◽  
Yimin Tang ◽  
Hongxia Wang ◽  
...  

Abstract Objective: The aim of this study was to investigate the long-term outcome of quality of life (QOL) in the lower-limb amputees 10 years after the 2008 Sichuan earthquake. Methods: In the cross-sectional study, 66 lower-limb amputees were recruited. The prosthetics-related QOL was assessed using the Prosthetic Evaluation Questionnaire (PEQ) in terms of the scales of utility, appearance, sounds, residual limb health, perceived response, frustration, social burden, ambulation, and well-being. The score of each PEQ subscale was calculated and compared among the cohorts with different demographic characteristics. Results: The PEQ scores showed that the scales of sounds, residual limb health, and frustration were still low in the lower-limb amputees 10 years after the 2008 Sichuan earthquake. The comparison of PEQ scales among cohorts with different demographic characteristics indicated that the potential demographic risk factors, namely, age, marital status, educational level, living independence, and comorbidity, were associated with prosthesis-related QOL. Conclusions: The prosthesis-related QOL of the lower-limb amputees 10 years after the 2008 Sichuan earthquake has been partly documented in this study. The potential demographic risk factors associated with QOL of amputees were also identified. These findings could enhance the understanding of prosthesis-related QOL of lower-limb amputees sustained in an earthquake and facilitate the optimization of post-disaster rehabilitation strategies.


2019 ◽  
Vol 41 (3) ◽  
pp. 364-374 ◽  
Author(s):  
Nadaby Maria Jesus ◽  
Gracielly Ferreira de Souza ◽  
Clesnan Mendes-Rodrigues ◽  
Omar Pereira de Almeida Neto ◽  
Deusdélia Dias Magalhães Rodrigues ◽  
...  

Abstract Introduction: Chronic kidney disease (CKD) negatively affects the physical and biopsychosocial aspects of the lives of individuals with the disease, thereby affecting the quality of life (QOL) of patients and their families. Objectives: This study aimed to measure the QOL of individuals with CKD and compare the QOL scores of patients with CKD to the scores of disease-free individuals to find factors associated with better QOL. Method: The local Ethics Committee approved this cross-sectional study. The study was carried out at a public clinic and a private hemodialysis clinic. Participants were asked to answer the WHOQOL-BREF and a sociodemographic questionnaire. Statistical tests were used according to the variables of interest and significance was attributed to differences with p-values < 0.05. Results: Nearly two thirds (59%) of the case group members were males and 55% did not have a spouse; 53% were seen at a private clinic and 57% had complications. The variables that more significantly affected QOL were smoking (perception of QOL) (Bi = - 0.4061; p = 0.032), undergoing hemodialysis (general health status) (Bi = - 0.3029; p = 0.034), and duration of sessions (Bi = 0.117; p = 0.039) (environmental domain). Conclusion: The QOL of patients with CKD was significantly lower when compared to controls in the physical and psychological domains. Several variables affected the perception of QOL and should be considered in clinical assessment.


2021 ◽  
Vol 21 (1) ◽  
pp. 427-36
Author(s):  
Yasin Ssewanyana ◽  
Badru Ssekitooleko ◽  
Bashir Suuna ◽  
Emmanuel Bua ◽  
Joseph Wadeya ◽  
...  

Introduction: Intestinal stomas remain important life-saving surgical options in a wide range of gastrointestinal pathologies globally. Living with a stoma has potential to impair the patient’s quality of life, often with associated negative psychological effects. Objective: To evaluate the quality of life among intestinal stoma patients under Mulago National Referral Hospital (MNRH), with emphasis on psychological effects and effects on family-social interactions. Methodology: A cross-sectional study carried out at surgical outpatient clinics of MNRH between January and June 2018. Data was collected using Stoma-QOL questionnaire, PHQ-9 and GAD-7 from 51 participants who had lived with intestinal stomas for at least a month. Results: Of the 51 participants, male: female ratio was 4:1 and aged 18-84 years (mean age 44.04+18.47 years). 76.5% had colostomy; 23.5% had ileostomy. Majority (88.2%) had temporary stomas. The overall mean Stoma-QOL score was 55.12+ 17.04. Only about a quarter (24%) of participants had Stoma-QOL scores >70 (best). Most patients exhibited negative psy- chological effects (anxiety-100%, concerns about changed body image - 96.1% and depression - 88.4%). Conclusion: Most participants had low levels of stoma-related quality of life, suffered negative psychological effects and exhibited limited social interactions. This calls for efforts to support Stoma patients adapt beter life. Keywords: Stoma; Quality of Life (Stoma-QOL); Psychological effects; Patient Health Questionnaire (PHQ-9); General- ized Anxiety Questionnaire (GAD-7).


2021 ◽  
Vol 32 (4) ◽  
pp. 453-458
Author(s):  
Elida Zairina ◽  
Gesnita Nugraheni ◽  
Gusti Noorrizka Veronika Achmad ◽  
Arie Sulistyarini ◽  
Yunita Nita ◽  
...  

Abstract Objectives Medication non-adherence mostly occurs in patients with a wide range of disease severity, including asthma. The aim of the study was to assess the self reported adherence to asthma therapy and investigate the relationship between adherence, asthma control and asthma-related quality of life. Methods The study was a cross-sectional study in which participants were recruited from an outpatient department, in one hospital in Surabaya. Patients (aged≥18 years) with asthma who had used any regular asthma medications were included. Standardised questionnaires, including Juniper’s Asthma Control Questionnaire (ACQ), Adherence to Refills and Medications Scales (ARMS) and Juniper’s Asthma Quality of Life Questionnaire (AQLQ) were used. Results A total of 82 adults with asthma were recruited in the study. Male participants’ mean age was 49.13 ± 14.10 years (n = 23). Approximately 59 participants (72.0%) were females, 30 participants (36.5%) were using Budesonide inhaler, and 73 participants (89.0%) never smoked. The mean of ACQ, AQLQ, and ARMS scores were 1.62 ± 1.19, 4.96 ± 1.24, and 16.98 ± 4.12, respectively. Of 82 patients studied 53 (64.6 %) had “uncontrolled asthma” and more than 85% participants both showed “non adherence” to asthma therapy and nearly 46% of them indicated that their quality of life was affected by asthma. There was a significant association between ACQ and AQLQ (p<0.05), whereas no statistically significant association was found between ACQ and ARMS. Conclusions The majority of patients reported non-adherence to asthma medications. Poor controlled asthma has been associated with lower asthma-related quality of life.


2021 ◽  
Vol 15 (2) ◽  
pp. 275-280
Author(s):  
Víctor de Oliveira Costa ◽  
Fabrício Machado Teixeira ◽  
Thais Medeiros Lopes ◽  
Henrique Pinto Gomide ◽  
Patricia Cardoso Clemente ◽  
...  

ABSTRACT. An amputation is an irreversible event that causes social, psychological, and functional consequences that reduces the quality of life of the amputee. Phantom pain generally is reported by 50 to 80% of amputees. Objective: To describe the pain and phantom sensation and quality of life among lower-limb amputees. Methods: This was a cross-sectional study carried out in the region of Juiz de Fora, state of Minas Gerais, Brazil. Inclusion criteria were being a patient in one of two hospitals in the region at the time of the interview and having at least one lower-limb amputation. A total of 20 amputees were included in the analysis. The interview questionnaire had items adapted from the Groningen Questionnaire Problems After Leg Amputation - describing the frequency and discomfort of phantom pain and sensation, causes and the level of the amputation, as well as the WHOQOL-BREF, for assessing quality of life. Results: Most participants were women (55%) and had a mean age of 55.6 years (SD=14.8). Femoral amputation was the most prevalent (65%), and diabetes (40%) was the main reason for amputation. 29% of amputees classified the phantom pain as moderate or severe, and 15% claimed daily frequency of this phenomenon. As for phantom pain, only 6% stated daily frequency. The mean quality of life was 4.1 (SD=1.1, five score means very satisfied), the physical domain of quality of life had the lowest mean (3.4, SD=0.7). Conclusions: Phantom sensation and pain were prevalent among lower-limb amputees who were, in general, less satisfied with their physical domain of quality of life.


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