scholarly journals One year randomized controlled trial to compare the effectiveness of honey dressing versus povidone iodine dressing for diabetic foot ulcer at Dr. Prabhakar Kore Hospital and MRC, Belagavi

2020 ◽  
Vol 7 (2) ◽  
pp. 506 ◽  
Author(s):  
Ramesh S. Koujalagi ◽  
V. M. Uppin ◽  
Soham Shah ◽  
Dron Sharma
Keyword(s):  
Randomized Controlled Trial ◽  
Diabetic Foot ◽  
Povidone Iodine ◽  
Controlled Trial ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Randomized Controlled ◽  
Wound Size ◽  
The Difference

Background: The objective of the study is to find out the effect of honey dressing versus povidone iodine dressing for reduction of wound size in diabetic foot ulcer.Methods: This randomized controlled trial was done in the Department of General Surgery, KLES Dr. Prabhakar Kore Hospital, Belagavi from January 2017 to December 2017. 64 patients were randomized into 32 group each undergoing unprocessed honey dressing and other group undergoing povidone iodine dressing.Results: The mean wound size in honey dressing was 23.16 cm2 and 23.03 cm2 in povidone dressings  at baseline, 23.16 cm2 and 22.94 cm2 at 1st day follow up, 23.16 cm2 and 22.94 cm2 at 3rd day follow up, 19.38 cm2 and  20.28 cm2 at 5th day follow up, 16.13 cm2 and 17.06 cm2 at 7th day follow up, 12.44 cm2 and  16.13 cm2 at 10th day follow up and the end of 15th day, it was 10.69 cm2 and 15.06 cm2 respectively in honey dressing group and povidone dressing group. The difference in the wound size in honey dressing group and povidone dressing group at 1st day, 3rd day, 5th day, 7th day, 10th day follow up period were statistically not significant (p>0.05). The difference in the wound size in honey dressing group at 15th day follow up period were statistically significant (p<0.05).Conclusions: This study shows more favorable results with honey dressing for reduction of wound size in diabetic foot ulcers.

scholarly journals Beraprost Sodium for Chronic Diabetic Foot Ulcer: A Randomized Controlled Trial in Thammasat University Hospital

2014 ◽  
Vol 7 (1) ◽  
pp. 40-45 ◽  
Author(s):  
Surajit Awsakulsutthi ◽  
Kwanjit Punpho ◽  
Jinpitcha Mamom ◽  
Pairat Baikrut ◽  
Patcharee Yingchoorod
Keyword(s):  
Randomized Controlled Trial ◽  
Diabetic Foot ◽  
Controlled Trial ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
University Hospital ◽  
Randomized Controlled ◽  
Beraprost Sodium

175-LB: Effect of a Telemedicine Diabetic Foot Ulcer Intervention on Health and Well-Being: A Cluster Randomized Controlled Trial

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 175-LB
Author(s):  
MARJOLEIN MEMELINK IVERSEN ◽  
JANNICKE IGLAND ◽  
HILDE SMITH-STRøM ◽  
TRULS OSTBYE ◽  
GRETHE S. TELL ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Diabetic Foot ◽  
Controlled Trial ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Well Being ◽  
Cluster Randomized Controlled Trial ◽  
Randomized Controlled ◽  
Cluster Randomized ◽  
Health And Well Being

scholarly journals GIZI UNTUK PROSES PENYEMBUHAN LUKA PADA PASIEN DENGAN DIABETIC FOOT ULCER (DFU): LITERATURE REVIEW

2021 ◽  
Vol 10 (1) ◽  
pp. 39-46
Author(s):  
Melani Puji Lestari ◽  
Niken Safitri Dyan Kusumaningrum
Keyword(s):  
Vitamin D ◽  
Randomized Controlled Trial ◽  
Vitamin E ◽  
Literature Review ◽  
Diabetic Foot ◽  
Controlled Trial ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Omega 3 ◽  
Randomized Controlled

Latar belakang: Asupan gizi merupakan salah satu faktor yang berperan penting dalam proses penyembuhan luka, khususnya Diabetic Foot Ulcer (DFU). Oleh karena itu, selain merawat kaki, pasien DFU sangat dianjurkan untuk memperhatikan diet dan gizi yang dikonsumsi.Tujuan: Penelitian ini bertujuan untuk mereview peran gizi pada proses penyembuhan DFU.Metode: Metode yang digunakan dalam penelitian ini adalah literature review yaitu mengkaji secara kritis temuan-temuan yang telah dipublikasikan sebelumnya. Artikel dari 3 database, yaitu SCOPUS, PubMed, dan Google Scholar yang sesuai dengan kriteria inklusi kemudian dianalisis untuk menjawab tujuan penelitian. Kriteria inklusi artikel yang disertakan dalan penelitian meliputi artikel yang telah dipublikasikan pada jurnal internasional dengan rentang publikasi dari Januari 2015 sampai Desember 2019, berupa Randomized Controlled Trial (RCT), dan  berbentuk full-text. Enam artikel dianalisis dan disintesis untuk mendapatkan hasil penelitian berdasarkan proses skrining, seleksi, dan pemilihan artikel.Hasil: Literature review ini menunjukkan bahwa gizi, baik dalam bentuk macronutrient (misalnya omega 3) maupun micronutrient (seng, magnesium, vitamin D, vitamin E, dan probiotik), berperan penting dalam proses penyembuhan luka DFU. Macro dan micronutrient ini berperan mulai dari proses modulasi proliferasi sel, metabolisme kolagen, serta sebagai biomarker fase inflamasi dan oksidasi. Asupan gizi yang tepat akan mengontrol dan menekan komplikasi DFU sehingga penyembuhan lukanya berjalan secara optimal. Omega-3, seng, magnesium, vitamin D, vitamin E, dan probiotik berperan besar dalam peningkatan produksi kolagen, sintesis protein, dan pembuangan bakteri serta sel - sel nekrotik.Simpulan: Baik macronutrient maupun micronutrient, keduanya dibutuhkan di dalam tubuh untuk mendukung proses penyembuhan luka DFU. Masing-masing komponen tersebut mempunyai peran penting dalam proses penyembuhan luka.

Topical propolis improves wound healing in patients with diabetic foot ulcer: a randomized controlled trial

2017 ◽  
Vol 32 (17) ◽  
pp. 2096-2099 ◽  
Author(s):  
Mozhgan Afkhamizadeh ◽  
Robab Aboutorabi ◽  
Hassan Ravari ◽  
Mohsen Fathi Najafi ◽  
Sajad Ataei Azimi ◽  
...  
Keyword(s):  
Wound Healing ◽  
Randomized Controlled Trial ◽  
Diabetic Foot ◽  
Controlled Trial ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Randomized Controlled

Citation Advantage of Promoted Articles in a Cross-Publisher Distribution Platform: 36-month Follow-up to a Randomized Controlled Trial (Preprint)

2021 ◽  
Author(s):  
Paul Kudlow ◽  
Tashauna Brown
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Control Group ◽  
Digital Tool ◽  
Randomized Controlled ◽  
Subject Areas ◽  
The Subject ◽  
The Difference ◽  
Citation Advantage

BACKGROUND There are limited evidence-based strategies that have been shown to increase the rate at which peer-reviewed articles are cited. In a previously reported randomized controlled trial we demonstrated that promotion of article links in an online cross-publisher distribution platform (TrendMD) persistently augments citation rates after 12 months, leading to a statistically significant, 50% increase in citations relative to control. OBJECTIVE To investigate if the citation advantage of promoted articles upholds after 36-months. METHODS Three thousand two hundred articles published in 64 peer-reviewed journals across eight subject areas were block randomized at the subject level to either the TrendMD group (n=1600) or the control group (n=1600) of the study. Articles were promoted in the TrendMD Network for 6 months. We compared the citation rates in both groups after 36 months. RESULTS At 36 months, we found the citation advantage endured; articles randomized to TrendMD showed a 28% increase in mean citations relative to control. The difference in mean citations at 36 months for articles randomized to TrendMD versus control was 10.52, 95% CI [3.79, 17.25] and was statistically significant (p=0.001). CONCLUSIONS To our knowledge, this is the first randomized controlled trial to demonstrate how a post-publication article promotion intervention can be used to persistently augment citations of peer-reviewed articles. TrendMD is an efficient digital tool for knowledge translation and dissemination to targeted audiences to facilitate uptake of research.

scholarly journals Manipulation Therapy Relieved Pain More Rapidly Than Acupuncture among Lateral Epicondylalgia (Tennis Elbow) Patients: A Randomized Controlled Trial with 8-Week Follow-Up

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Chung-Yuan Hsu ◽  
Ko-Hung Lee ◽  
Hsin-Chia Huang ◽  
Zi-Yu Chang ◽  
Hsing-Yu Chen ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Biceps Brachii ◽  
Tennis Elbow ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Lateral Epicondylalgia ◽  
The Difference ◽  
Dash Questionnaire ◽  
Radial Bone

Radial bone adjustment manipulation treatment may be effective to reduce pain rapidly in lateral epicondylalgia patients and the pathological tension in the biceps brachii muscle is highly concerned. To prove this hypothesis, we conducted a randomized controlled trial and included 35 patients with lateral epicondylalgia for more than 2 months. Either manipulation treatment (n=16) or acupuncture (n=19) was given to these patients for 2 weeks and all patients’ symptoms were followed up for 8 weeks after treatment. Both groups demonstrated changes in pain VAS score, grip strength, and DASH questionnaire. Lateral epicondylalgia patients who received manipulation treatment felt pain relief sooner than those who had acupuncture treatments during the first few treatments. However, both acupuncture and manipulation are effective, while the difference has no significance at the 8-week follow-up. The trial was registered with Current Controlled TrialsISRCTN81308551on 5 February 2016.

scholarly journals DIABETIC FOOT ULCERS;

2019 ◽  
Vol 26 (02) ◽  
Author(s):  
SOHAIL Farooq ◽  
Shaukat Javed ◽  
Nazish Jahan
Keyword(s):  
Granulation Tissue ◽  
Diabetic Foot ◽  
Controlled Trial ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Wound Size ◽  
Group A ◽  
Group B

Introduction: Traditionally, moist dressings are being in used routinely by surgeons for management of diabetic foot ulcers. Recently, there is an encouraging trend of using VAC dressings in such patients. This study aimed to compare the outcome of VAC with moist dressing for management of diabetic foot ulcer. Study Design: Prospective randomized controlled trial. Setting: Department of Surgery, Al-Bukyriah General Hospital, Al-Bukayriah, Alqaseem KSA. Period: June 2012 to 07 December 2016. Methods and Material: 200 patients with diabetic foot ulcers. The patients were divided in two equal groups containing 100 patients each. In group A, 100 patients received VAC dressing treatment while in group B, 100 patients received wet dressings. Wound size, % reduction in wound size, appearance of granulation tissue and fate of wound were main outcome measured which were noted at start of study and at the end of study (4th week of therapy). Results: In group A, there were 73 (73%) men and 27 (27%) women with a mean age of 54.98+7.68 years and in group B, there were there were 75 (75%) men and 25 (25%) women with a mean age of 55.23+6.98 years. Size of wound before treatment in group A was 14.23± 6.78 cm2 which reduced to 5.11±1.91 cm2 at 4th wee and in group B it was 14.41±5.93 cm2 in the start which reduced to 11.29±3.63 cm2 at 4th week (p<0.05). Mean %reduction in wound size in group A was 63.22±9.19 and 22.92±7.18 in group B (p<0.05). In group A, 43 (43%) wounds healed spontaneously with shrinkage and group B only 2(2%) healed spontaneously (p<0.05). Conclusions: VAC therapy is superior to moist dressing in terms of achieving early granulation tissue, reduction in wound size and spontaneous wound shrinkage.

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