scholarly journals An assessment of the pattern of congenital heart disease in children: study in a tertiary care hospital, Rajshahi, Bangladesh

Author(s):  
Kuntal Roy ◽  
Humayun Shahed ◽  
Kaushik Roy ◽  
Quazi Sahely Sarah ◽  
Nandita Sur Chowdhury

Background: Congenital heart disease is defined as a gross structural abnormality of the heart or intrathoracic great vessels that is actually or potentially of functional significance. The aim of this study was to assess the pattern of congenital heart disease.  Methods: It was a hospital based Cross-sectional study carried out prospectively in the department of pediatrics of Rajshahi medical college and hospital from July 2011 to December 2011. The study population was all the children up to 12 years of age admitted in three pediatric units of this hospital during the study period.Results: Among the 147 clinically suspected cases congenital heart disease was confirmed in 110 cases by echocardiography. Thrill was mostly present in 60.5% of VSD cases, in 42.1% of PDA, in 50% of A-V canal defect and 10% of multiple lesions patients. Palpable P2 was present in 27.9% of VSD cases, 15% of TOF, 50% of PS and 30% of multiple lesions patients. Left parasternal heave was found in 25.6% of VSD cases, 15.6% of ASD, 88.2% of TOF, 50% of PS and 40% of multiple lesions patients. Cardiomegaly was present in 5.3% of PDA, 50% of COA, 50% of PS and 20% of multiple lesions cases. Plethoric lung field with cardiomegaly & consolidation was observed in 10% of VSD and 21% of PDA cases. Cardiomegaly with consolidation was observed in 11.6% of VSD & 15.6% of ASD cases. Boot shape heart with oligamic lung was observed in 88.2% of TOF patients. Pulmonary opacity/consolidation was found in 4.7% of VSD cases.Conclusions: It appeared that incidence of CHD is quite significant in RMCH.

2020 ◽  
Vol 13 (4) ◽  
pp. 163-165
Author(s):  
Misbah Majeed ◽  
Muhammad Ashfaq ◽  
Bader U Nisa ◽  
Aijaz Ahmed ◽  
Jai Parkash

Background: Congenital heart disease (CHD) is one of the frequent congenital health issues in neonates. Early diagnosis is a key factor to combat this problem. This study aims to assess the frequency and common types of CHD among neonates presenting to a tertiary care hospital, Karachi. Patients and methods: This descriptive cross-sectional study was conducted in a Neonatal Intensive Care Unit (NICU) of National Institute of Child Health (NICH), Karachi from March to September 2017. All neonates of gestational age ≥37 weeks with suspected CHD (presence of blue-tinged skin, i.e. cyanosis on routine clinical examination) were included. Information regarding presence of CHD and its types were collected along with the demographic characteristics and history of the patients. Results: Of 134, frequency of CHD was observed in 126 (94%) patients. Out of these 126 CHD patients, Ventricular septal defect (VSD) was observed in 49 (38.9%), patent ductal arteriosus (PDA) in 29 (23%), atrial septal defect (ASD) was observed in 19 (15.1%), Transposition of great arteries (TGA) in 18 (14.3%), and tetralogy of Fallot (TOF) in 14 (11.1%) patients. A significant association of VSD was observed with neonatal age (p = <0.001), ASD with neonatal age (p = 0.037) and maternal age (p = 0.025), while TGA was found significantly associated with neonatal age (p<0.001). Conclusion: CHD was observed in majority of the suspected patients with VSD as commonest type of congenital heart diseases among neonates.


2019 ◽  
Vol 31 (2) ◽  
pp. 35-38
Author(s):  
Md Belal Uddin ◽  
Md Belal Hossain ◽  
Khalilur Rahman ◽  
Nigar Sultana ◽  
Md Manirul Haque Tarafder ◽  
...  

Congenital heart disease is most common heart disease in children and causes significant morbidity and mortality. This study was done to evaluate the frequency and pattern of congenital heart disease in neonates (age ≤ 28 days) admitted in a tertiary care level hospital. It was a cross-sectional descriptive type of study conducted at the Department of Paediatrics of Rajshahi Medical College Hospital from January 2014 to December 2015. Among the 4120 neonates admitted in RMCH in that period, 52 cases had cardiac murmur on auscultation. Incidence of cardiac murmur in the newborn was 1.26%. Clinically, among the 52 cases, 40 cases were thought to have pathological murmur and 12 cases were thought to have innocent murmur. During echocardiography, structural cardiac defect (congenital heart disease) was detected in 38 cases. So, incidence of congenital heart disease was 9.22/ 1000 live births. Remaining 14 cases had normal cardiac anatomy in echocardiography. VSD (12 cases) was the most common type of acyanotic congenital heart disease (23.08%) followed by ASD (11 cases) and PDA (6 cases). Among the cyanotic congenital heart disease, tetralogy of Fallot was the most common abnormality and it was found in 4 cases (7.69%). In this study, parental consanguinity was detected in 4 cases (7.69%). Early diagnosis, timely referral and proper management of congenital heart can save valuable lives and allow normal growth and development. TAJ 2018; 31(2): 35-38


2020 ◽  
Vol 10 (5) ◽  
pp. 353-361
Author(s):  
Mirela Bojan ◽  
Laurence Pieroni ◽  
Cristian Mirabile ◽  
Marc Froissart ◽  
Damien Bonnet

Background: The onset of chronic kidney disease (CKD) is an important prognostic factor in young adults with congenital heart disease (CHD). Although it is likely that CKD is manifest early in CHD patients, the prevalence among adolescents is still unknown. The National Kidney Foundation’s Kidney Disease Improving Global Outcomes guidelines 2012 recommend new equations for the estimated glomerular filtration rate (eGFR) and highlight the importance of albuminuria for CKD screening. The objective of the present study was to estimate the prevalence of CKD in CHD adolescents. Methods: This observational cross-sectional study included 115 patients aged 10–18 years attending the cardiologic outpatient clinic at our institution as a follow-up after cardiac surgery in infancy related to various CHDs. CKD assessment used the CKD criteria 2012, including eGFR equations based on serum creatinine and cystatin C, and measurement of albuminuria. Results: No patient had an eGFR <60 mL min–1 1.73 m–2. However, 28.7% of all patients (95% CI 20.7–37.9) had eGFRbetween 60 and 89 mL min–1 1.73 m–2 when estimated by the bedside Schwartz creatinine-based equation,and 17.4% (95% CI 11.2–24.1) had eGFRbetween 60 and 89 mL min–1 1.73 m–2 when estimated by the Zappitelli equation, combining creatinine and cystatin C. Of all patients, 20.0% (95% CI 12.1–26.7) had orthostatic proteinuria, and none had persistent albuminuria. Conclusions: There was no evidence of CKD in the present population aged 10–18 years. The significance of an eGFR between 60 and 90 mL min–1 1.73 m–2 is not concordant for this age range and requires further investigations.


2016 ◽  
Vol 8 (10) ◽  
pp. 288 ◽  
Author(s):  
Pedram Nazari ◽  
Mohammad Davoodi ◽  
Mohammad Faramarzi ◽  
Mohammad Bahadoram ◽  
Nozar Dorestan

<p><strong>BACKGROUND:</strong> Congenital heart disease (CHD) refers to complex abnormalities that affect the structure or function of the heart due to embryonic defects. There is little accurate statistical data about prevalence, incidence and frequency in many developing countries such as Iran. The aim of this study was to evaluate the frequency of CHD in patients who were referred to the Department of Pediatric Cardiology in a large single-center in Southwestern of Iran.</p><p><strong>METHODS:</strong> This is a retrospective, cross-sectional study. Patients with various cardiac malformations were each investigated separately. A check list was used to collect information. It was comprised of three parts; demographic characteristics, Patient’s birth details and maternal data.</p><p><strong>RESULTS:</strong> The frequency of ventricular septal defect (VSD), atrial septal defect (ASD) and tetralogy of fallot (TOF) were 125 (28.47%), 48 (10.93%) and 41(9.3%) respectively. Family history was reported in 26(11.1%) cases. Down syndrome, skeletal anomaly and hematological anomaly were the most common co-anomalies. Parental consanguinity was 48.7%.</p><p><strong>CONCLUSIONS:</strong> Present study showed that VSD was the most common CHD subtype followed by family history, familial marriage, extra cardiac anomalies (ECAs), birth weight, and maternal concomitant disease. But there was a controversial relationship between birth order and drug history in CHD.</p>


Author(s):  
Subha Sivagami Sengodan ◽  
Shobhika Selvaraj

Background: Incidence of pregnancy in women with heart disease is increasing due to the increasing number of women with congenital heart disease. Although most cardiac conditions are well tolerated during pregnancy, there are some conditions that have adverse fetal and maternal outcome. Objective of this study is to study the prevalence of heart disease in antenatal mothers and fetal outcome with obstetric management.Methods: This is a prospective observational study carried out in the Department of Obstetrics and Gynaecology at Government Mohan Kumaramangalam Medical College and Hospital during January 2018 to March 2019 for a period of fifteen months. Authors included 149 antenatal mothers with heart disease and analysed the data using percentage analysis through excel software.Results: Incidence of heart disease in pregnancy was observed to be 1.2%. Rheumatic heart disease being 73.8%, congenital being 22.8% and complete heart block was 3.4%. Among rheumatic heart disease mitral stenosis was the most common lesion. Atrial septal defect was the most common congenital heart disease. The mean gestational age of delivery was 37 to 38 weeks. 58% delivered by vaginal route. Most common neonatal complication was prematurity. Pregnancy and neonatal outcome were favorable.Conclusions: Heart disease complicating pregnancy has increased due to late marriage, obesity, hypertension and diabetes. Early referral, regular follow-up and multi-disciplinary approach with tertiary care back-up will bring a favorable maternal and neonatal outcome in patients with heart disease.


2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Saad Khoshhal ◽  
Khaled Al-Harbi ◽  
Ibrahim Al-Mozainy ◽  
Saeed Al-Ghamdi ◽  
Adnan Aselan ◽  
...  

Abstract Background and aims Health-related quality of life (HRQOL) has garnered increasing interest especially for health care providers and researchers. The study aims to evaluate the HRQOL in parents of congenital heart disease (CHD) children, and to clarify the effect of the disease severity on the outcome of the HRQOL perception. Also, to analyze the internal consistency of the Arabic version of the World Health Organization (WHO) QOL-BREEF tool in order to determine whether the tool had good validity for the target population. Methods A cross-sectional study. The HRQOL perception was evaluated using WHOQOL-BREF questionnaire, and the internal consistency of the tool was tested using Cronbach’s alpha (α-C), Results The study sample consisted of 200 individuals, 120 parents of CHD children, compared to 80 parents of children with minor illnesses (mean age of participating parents = 35.1 ± 9.8 years). While evaluating the HRQOL, the group of parents of children with minor illnesses had higher scores than the total group of parents of CHD children in all domains, indicating a better HRQOL. Class-IV subgroup of parents of CHD children showed the most significant lower total score of domains between all classes (44.47 ± 12, p < 0.001). With respect to the internal consistency of the WHOQOL-BREF, estimation of α-C values were 0.84 points for the group of parents of CHD children, and 0.87 for the group of parents of children with minor illnesses. Conclusions This short-term study emphasized that, HRQOL scores among parents of CHD children are compromised, and the severity of their children illness significantly affect the total score of domains in their HRQOL perception. Furthermore, the tool showed to be practical and efficient to evaluate the QOL of parents of CHD children in our population in future researches.


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