Croup as a manifestation of COVID-19 in infancy: a case series

The second wave of the COVID-19 pandemic in India brought with it an emerging clinical spectrum of the infection in children. Amongst these is the rarely reported presentation of croup, which otherwise remains a common clinical condition in infants caused by a variety of viruses and seen by pediatricians regularly. Airway manifestations of COVID-19 require reporting and unless their evaluation brings up any specific peculiarities, it is imperative to screen all such children presenting to the emergency department for SARS-CoV-2 infection. We hereby reported a series of three infants who were brought to us with typical features of croup including a mild fever, runny nose and indicators of subglottic inflammation including a hoarse voice, brassy cough and an inspiratory stridor. Each of them responded to conventional therapies for croup. However, the added conundrum of possible SARS-CoV-2 infection increases the relevance of rapid screening, assessment for complications and counselling in children presenting with croup.

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Faculty Opinions recommendation of A prospective case series of pediatric procedural sedation and analgesia in the emergency department using single-syringe ketamine-propofol combination (ketofol).

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5770964.5753063 ◽

2010 ◽

Author(s):

Joseph Cravero ◽

Daniel S Tsze

Keyword(s):

Emergency Department ◽

Case Series ◽

Procedural Sedation ◽

Procedural Sedation And Analgesia ◽

Sedation And Analgesia ◽

Prospective Case Series

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Thrombosed Urethral Prolapse: a case series and review of the literature

Journal of Clinical Urology ◽

10.1177/20514158211032853 ◽

2021 ◽

pp. 205141582110328

Author(s):

Abisola Oliyide ◽

Ijeoma Chibuzo ◽

Magda Kujawa

Keyword(s):

Clinical Condition ◽

Correct Diagnosis ◽

Age Distribution ◽

Case Series ◽

Review Of The Literature ◽

Level Of Evidence ◽

Case Presentation ◽

Urethral Prolapse ◽

Evidence Level

Thrombosed urethral prolapse is a rare clinical condition. In this context, we describe our experience and compare our findings with the literature, following presentation of five consecutive cases over 2 years. This will hopefully improve awareness and appropriateness of specialty referrals as a correct diagnosis is rarely established prior to the patient being seen by a urologist. We also wish to highlight a case presentation of thrombosed urethral prolapse outside the bimodal age distribution which has been recorded in the literature. Level of Evidence: Level 4

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Medication-Related Osteonecrosis of the Jaw (MRONJ): Are Antiresorptive Drugs the Main Culprits or Only Accomplices? The Triggering Role of Vitamin D Deficiency

Nutrients ◽

10.3390/nu13020561 ◽

2021 ◽

Vol 13 (2) ◽

pp. 561

Author(s):

Luca Dalle Carbonare ◽

Monica Mottes ◽

Maria Teresa Valenti

Keyword(s):

Vitamin D ◽

Clinical Condition ◽

Case Series ◽

Osteonecrosis Of The Jaw ◽

First Case ◽

Vitamin D Levels ◽

Exposed Bone ◽

Antiresorptive Drugs ◽

Almost All

Osteonecrosis of the jaw (ONJ) is a severe clinical condition characterized mostly but not exclusively by an area of exposed bone in the mandible and/or maxilla that typically does not heal over a period of 6–8 weeks. The diagnosis is first of all clinical, but an imaging feedback such as Magnetic Resonance is essential to confirm clinical suspicions. In the last few decades, medication-related osteonecrosis of the jaw (MRONJ) has been widely discussed. From the first case reported in 2003, many case series and reviews have appeared in the scientific literature. Almost all papers concerning this topic conclude that bisphosphonates (BPs) can induce this severe clinical condition, particularly in cancer patients. Nevertheless, the exact mechanism by which amino-BPs would be responsible for ONJ is still debatable. Recent findings suggest a possible alternative explanation for BPs role in this pattern. In the present work we discuss how a condition of osteomalacia and low vitamin D levels might be determinant factors.

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Cannabis-induced psychosis presenting to a psychiatric emergency department: a case series

Journal of Substance Use ◽

10.1080/14659891.2021.1968967 ◽

2021 ◽

pp. 1-4

Author(s):

Chia-Heng Lin ◽

Chia-Hsiang Chan

Keyword(s):

Emergency Department ◽

Case Series ◽

Psychiatric Emergency

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Perineural Dexamethasone as a Peripheral Nerve Block Adjuvant in the Emergency Department: A Case Series

Journal of Emergency Medicine ◽

10.1016/j.jemermed.2021.03.032 ◽

2021 ◽

Vol 61 (5) ◽

pp. 574-580

Author(s):

Nicole M. Duggan ◽

Arun Nagdev ◽

Bryan D. Hayes ◽

Hamid Shokoohi ◽

Lauren A. Selame ◽

...

Keyword(s):

Emergency Department ◽

Peripheral Nerve ◽

Nerve Block ◽

Peripheral Nerve Block ◽

Case Series

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A Survey on Effectiveness of B. K.S. Iyengar Yoga Plan for Cold

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i29a31564 ◽

2021 ◽

pp. 43-49

Author(s):

Parul Baghel

Keyword(s):

Side Effects ◽

Viral Infection ◽

The Body ◽

Upper Respiratory Tract ◽

Blurred Vision ◽

Medical Practitioners ◽

Runny Nose ◽

Initial Symptoms ◽

Current Survey ◽

Mild Fever

Cold is generally characterized by initial symptoms of a stuffy nose, sore throat, runny nose, mild fever, headache, mild fever. Infection of cold is a viral infection. The cold lasts for a maximum of two weeks. Cold primarily affects the nose and throat, mainly the upper respiratory tract and throat are affected. The cause of cold is a viral infection, many viruses are responsible for cold. The treatment prescribed by medical practitioners involves analgesic, antihistamine, decongestant, nasal steroids. All medicines show side effects like dizziness, drowsiness, blurred vision. Thus, there is a need to find a treatment for a cold having no therapeutic side effects. Yoga is now a days followed as a way to live a healthy life. B.K.S Iyengar yoga focuses on precise physical ailment of the body with particular postures. Very few studies on the effectiveness of B.KS Iyengar yoga have been conducted. The current survey focuses on finding the efficacy of performing specific yoga sequences for cold.

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COVID outcome prediction in the emergency department (COPE): using retrospective Dutch hospital data to develop simple and valid models for predicting mortality and need for intensive care unit admission in patients who present at the emergency department with suspected COVID-19

BMJ Open ◽

10.1136/bmjopen-2021-051468 ◽

2021 ◽

Vol 11 (9) ◽

pp. e051468

Author(s):

David van Klaveren ◽

Alexandros Rekkas ◽

Jelmer Alsma ◽

Rob J C G Verdonschot ◽

Dick T J J Koning ◽

...

Keyword(s):

Intensive Care Unit ◽

Emergency Department ◽

Intensive Care ◽

Outcome Prediction ◽

Characteristic Curve ◽

Hospital Death ◽

Hospital Data ◽

Dutch Hospital ◽

Icu Admission ◽

Second Wave

ObjectivesDevelop simple and valid models for predicting mortality and need for intensive care unit (ICU) admission in patients who present at the emergency department (ED) with suspected COVID-19.DesignRetrospective.SettingSecondary care in four large Dutch hospitals.ParticipantsPatients who presented at the ED and were admitted to hospital with suspected COVID-19. We used 5831 first-wave patients who presented between March and August 2020 for model development and 3252 second-wave patients who presented between September and December 2020 for model validation.Outcome measuresWe developed separate logistic regression models for in-hospital death and for need for ICU admission, both within 28 days after hospital admission. Based on prior literature, we considered quickly and objectively obtainable patient characteristics, vital parameters and blood test values as predictors. We assessed model performance by the area under the receiver operating characteristic curve (AUC) and by calibration plots.ResultsOf 5831 first-wave patients, 629 (10.8%) died within 28 days after admission. ICU admission was fully recorded for 2633 first-wave patients in 2 hospitals, with 214 (8.1%) ICU admissions within 28 days. A simple model—COVID outcome prediction in the emergency department (COPE)—with age, respiratory rate, C reactive protein, lactate dehydrogenase, albumin and urea captured most of the ability to predict death. COPE was well calibrated and showed good discrimination for mortality in second-wave patients (AUC in four hospitals: 0.82 (95% CI 0.78 to 0.86); 0.82 (95% CI 0.74 to 0.90); 0.79 (95% CI 0.70 to 0.88); 0.83 (95% CI 0.79 to 0.86)). COPE was also able to identify patients at high risk of needing ICU admission in second-wave patients (AUC in two hospitals: 0.84 (95% CI 0.78 to 0.90); 0.81 (95% CI 0.66 to 0.95)).ConclusionsCOPE is a simple tool that is well able to predict mortality and need for ICU admission in patients who present to the ED with suspected COVID-19 and may help patients and doctors in decision making.

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