scholarly journals Complicated malaria: relationship of complications and parasite load to outcome

2018 ◽  
Vol 5 (1) ◽  
pp. 186
Author(s):  
G. Keshava Anand ◽  
Mallikarjun Rao Sanda
Keyword(s):  
Plasmodium Falciparum ◽  
Treatment Plan ◽  
General Medicine ◽  
Parasite Load ◽  
Complicated Malaria ◽  
Appropriate Treatment ◽  
Probability Of Death ◽  
Relationship Of ◽  
The Relationship ◽  
Day By Day

Background: The incidence of complicated malaria cases is increasing day by day. Complicated malaria present in different ways in different places globally. If malaria is diagnosed and treated immediately, then the death rate is less than one percent. The objective was to study the relationship of complications and parasite load to outcome (mortality) among patients with complicated malaria.Methods: The present hospital based Prospective Observational study was carried out among 100 cases of “Complicated malaria.” The present study was carried out at Department of General medicine, Kamineni hospitals, L. B. Nagar, Hyderabad.Results: 71% patients were infected with Plasmodium falciparum, 25% with Plasmodium vivax and 4% with both Plasmodium falciparum and vivax. 12% patients deceased and 88% survived. The relationship between GCS, convulsions, pH, bicarbonate, lactate, hemoglobin, creatinine, SBP, PaO2/FiO2 ratio, PT, INR, aPTT, and outcome was statistically highly significant (p=0.000). The relationship between Total Bilirubin, RBS and outcome was statistically not significant (p=0.351). Multivariate analysis using logistic regression model, to determine the effect of studied variables on the final outcome, revealed no significant influence of studied variables in predicting the outcome (p>0.05). The relationship between increasing parasite load and outcome was studied, and it showed it was statistically highly significant (p=0.000).Conclusions: The prognosis and outcome of patients with complicated malaria worsen as the parasite load increases and the probability of death increases markedly in such patients. The presentation of inappropriate parameters at admission, aid us in predicting poor outcome and appropriate treatment plan.

scholarly journals The relationship of Plasmodium falciparum humeral immunity with HIV-1 immunosuppression and treatment efficacy in Zambia

2009 ◽  
Vol 8 (1) ◽  
pp. 258 ◽  
Author(s):  
Jean-Pierre Van Geertruyden ◽  
Erika Van Eijk ◽  
Francisca Yosaatmadja ◽  
Webster Kasongo ◽  
Modest Mulenga ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Treatment Efficacy ◽  
Relationship Of ◽  
The Relationship ◽  
Hiv 1

The Brain and Body on Stress

2018 ◽  
Author(s):  
Bruce S. McEwen ◽  
Natalie L. Rasgon
Keyword(s):  
Allostatic Load ◽  
General Medicine ◽  
The Body ◽  
Metabolic Hormones ◽  
Increased Risk ◽  
Health Promoting ◽  
Relationship Of ◽  
Brain Insulin Resistance ◽  
The Relationship ◽  
The Brain

Neuroscientists have treated the brain in isolation from the rest of the body, while endocrinology and general medicine have viewed the body largely without regard to the influence of systemic physiology and pathophysiology on higher brain centers outside of the hypothalamus and pituitary gland. But now there is greater recognition of brain–body interactions affecting the limbic and cognitive systems of brain and altering systemic physiology; these are conceptualized as allostasis and allostatic load and overload. These concepts look at both the interactions of brain and body to stressors and health-promoting and health-damaging behaviors, and they help integrate behavior and mood with systemic functions. These interactions involve genetic predispositions and epigenetic alterations mediated by circulating steroid and metabolic hormones. Comorbidity and multi-morbidity of disorders will be illustrated by the relationship of systemic and brain insulin resistance to the psychopathology of depression and to the increased risk for dementia.

Algorithm of diagnosis and treatment of patients with distal occlusion in the period of replacement bite

2021 ◽  
pp. 56-60
Author(s):  
N.S. Tuturov ◽  
O.V. Voeykova ◽  
V.G. Lebedev ◽  
Yu.Yu. Bosykh ◽  
N.L. Lezhava ◽  
...  
Keyword(s):  
Treatment Plan ◽  
Young Patients ◽  
Treatment Method ◽  
Subsequent Treatment ◽  
Occlusal Plane ◽  
Class Ii Malocclusion ◽  
Three Stages ◽  
Relationship Of ◽  
Distal Occlusion ◽  
The Relationship

The article is devoted to treatment methods of young patients with class II malocclusion suffering from temporomandibular joint (TMJ) dysfunction. The authors proposed the improved treatment plan for the studied patients, which implies three stages: the first is a comprehensive functional analysis of the dental-maxillofacial system using digital technologies, the second one is the design, milling, manufacturing of occlusal overlays that allow to control occlusal plane slope and the last one is overlays luting and subsequent treatment with the help of aligners in order to normalize the relationship of the upper and lower teeth in three perpendicular planes with of retrusion control achieving. The described treatment method is disclosed in a clinical example.

scholarly journals GIS-Based Spatial Model for Habitat Suitability of Babirusa (Babyrousa celebensis), in Gorontalo Province

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Muhamad Khairul Rosyidy ◽  
Adi Wibowo
Keyword(s):  
Land Use ◽  
Spatial Modeling ◽  
Spatial Model ◽  
International Union ◽  
Traditional Markets ◽  
Validation Test ◽  
Suitable Area ◽  
Relationship Of ◽  
The Relationship ◽  
Day By Day

<p>Babirusa (<em>Babyrousa celebensis</em>) is an endemic animal from Gorontalo Province whose population is declining day by day due to poaching, land clearing, and selling babirusa meat in traditional markets in Gorontalo Province. Since 1931 this species has begun to be protected in Indonesia, and since 2008, <em>International Union for Conservation of Nature (</em>IUCN) named the babirusa species as a vulnerable category. This study aims to determine the suitability of babirusa habitat areas (<em>Babyrousa celebensis)</em> in Gorontalo Province with a Geographic Information System (GIS) approach and to determine the relationship of physical characteristics for the habitat of the babirusa habitat in Gorontalo Province. The variables are land use, slope, and elevation. The method used is GIS spatial modeling with overlay analysis. From the results of the analysis, it has concluded that a suitable area as a babirusa habitat is only about 33% of the total area of Gorontalo Province and there are types of land use in the wilderness and swamps at an elevation of 0-500 msl with sloping 0-8%. The validation test shows that Coefficient kappa is 0.16 and overall accuracy is 58%. Therefore, further research is needed by adding other variables to delineate the spatial distribution of babirusa.<em></em></p><p><strong><em>Keywords</em></strong><em>: babirusa, habitat, GIS, suitability area</em></p>

The relationship of the scleractinian corals to the rugose corals

Paleobiology ◽  
1980 ◽  
Vol 6 (02) ◽  
pp. 146-160 ◽  
Author(s):  
William A. Oliver
Keyword(s):  
Critical Points ◽  
Scleractinian Corals ◽  
Convincing Evidence ◽  
Early Triassic ◽  
Rugose Corals ◽  
History Of ◽  
The Subject ◽  
Relationship Of ◽  
The Relationship ◽  
Biologic Factors

The Mesozoic-Cenozoic coral Order Scleractinia has been suggested to have originated or evolved (1) by direct descent from the Paleozoic Order Rugosa or (2) by the development of a skeleton in members of one of the anemone groups that probably have existed throughout Phanerozoic time. In spite of much work on the subject, advocates of the direct descent hypothesis have failed to find convincing evidence of this relationship. Critical points are:(1) Rugosan septal insertion is serial; Scleractinian insertion is cyclic; no intermediate stages have been demonstrated. Apparent intermediates are Scleractinia having bilateral cyclic insertion or teratological Rugosa.(2) There is convincing evidence that the skeletons of many Rugosa were calcitic and none are known to be or to have been aragonitic. In contrast, the skeletons of all living Scleractinia are aragonitic and there is evidence that fossil Scleractinia were aragonitic also. The mineralogic difference is almost certainly due to intrinsic biologic factors.(3) No early Triassic corals of either group are known. This fact is not compelling (by itself) but is important in connection with points 1 and 2, because, given direct descent, both changes took place during this only stage in the history of the two groups in which there are no known corals.

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