scholarly journals Evaluation of coverage and compliance to mass drug administration for lymphatic filariasis elimination in two endemic districts of Karnataka

Author(s):  
Anwith H. Shivalingaiah ◽  
Ravikumar K. ◽  
Sunil M. Gurupadaswamy

Background: Lymphatic filariasis is a debilitating and disfiguring disease causing significant socioeconomic burden. India is endemic for filariasis which includes Kalaburagi and Yadgir districts in Karnataka. India has the target for filariasis elimination by 2020 and mass drug administration [MDA] is a strategy for elimination. The objective of the study was to evaluate the coverage and compliance of mass drug administration against lymphatic filariasis.Methods: The study was a cross sectional study conducted during the month of October 2018 in Kalaburagi and Yadgir districts. The study subjects included all the residents of cluster except subjects aged below 2 years and pregnant women. Multi stage sampling was used and three clusters from rural area and one cluster from urban area from each district. Data collection was done by household survey after informed consent using a standard questionnaire.Results: A total population of 1,963 subjects residing in 399 houses of two districts was included. Majority of the study subjects 1517 (77.27%) were in the age group of more than 15 years with predominantly males 984(50.12%). The coverage rate and compliance rate of MDA was 83.17% and 92.46% in Kalaburagi district and 86.71% and 86.98% in Yadgir district respectively. The effective coverage rate and coverage compliance gap was 76.89% and 7.53% in Kalaburagi district, 75.42% and 13.01% in Yadgir district. Incomplete dose of MDA was consumed by 17 subjects in Kalaburagi district and 21 subjects in Yadgir district.Conclusions: The effective MDA coverage in both the study districts is below 85% which is not satisfactory.

Healthline ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 94-99
Author(s):  
Huluvadi Shivalingaiah Anwith ◽  
S R Suhas ◽  
Seema K S ◽  
Karishma P S ◽  
K Ravi Kumar ◽  
...  

Introduction: Lymphatic filariasis or elephantiasis is the most debilitating and disfiguring scourge among all diseases which imposes severe social and economic burden. Currently an estimated 63crores people are at a risk of filariasis in 256 endemic districts across 16 states and 5 union territories in India. National filarial control programme is operational since 1955 in India and the current goal is achieving elimination of filariasis by 2020through Mass Drug Administration (MDA). Objective: To assess the coverage, compliance and causes for noncompliance of MDA in the study districts. Method: A cross sectional descriptive study was conducted in October 2019 and January 2020 in Koppal and Bidar districts respectively. Randomly four clusters were selected, three from rural area and one from urban area. All the residents of a cluster were included except subjects aged below 2 years and pregnant women. Data collection was done by household survey using a standard questionnaire. Results: Total populations of 2043 subjects residing in 480 houses were included. The coverage rate was95.44 &94.73% with compliance rate of 91.61% &93.12% in Koppal & Bidar districts, respectively. The effective coverage rate was 87.44 %& 88.2% in Koppal & Bidar districts respectively. Drug consumption by DOT was 95.1% in Koppal&85.8% in Bidar district. Conclusions: The coverage& compliance of MDA was found to be satisfactoryas it was >65%.Consumption of MDA by DOT to be more emphasized to reduce coverage compliance gap and increase the effective coverage rate.


Author(s):  
Rajeshwar Rao Alwala ◽  
Chandrasekhar Reddy Bolla ◽  
Shankar Reddy Dudala ◽  
Y. Pravin Raju ◽  
Raston Mondal ◽  
...  

Background: Lymphatic filariasis (LF) is an important public health and socio-economic problem in the world and it was identified as one of the six diseases, which could be targeted for elimination /eradication. Annual mass drug administration of DEC with selective vector control could result in the effective elimination of infection by interruption of transmission. The present study aimed to find the coverage and compliance of mass drug administration (MDA) of diethyl-carbamazine (DEC) for elimination of lymphatic filariasis (LF) in Khammam district in November 2009.Methods: Cross-sectional, population-based, house-to-house survey was conducted after the round of MDA with DEC. Multi-stage systematic sampling method was used and four clusters were selected with 30 houses in each. A pretested questionnaire was used to interview the study participants. The data collected was analyzed and coverage rate, compliance rate and effective coverage rate were calculated.Results: The coverage rate was 65.54% with variation across different areas. The compliance with drug ingestion was 71.14%. The effective coverage (46.63%) was much below the target (85%) which has to be targeted by intensive information, education and communication (IEC). Side effects of DEC were minimum, transient and drug-specific.Conclusions: The coverage, compliance, and effective coverage rates were found to be lower than the target, which need to be intensified by extensive IEC. 


2020 ◽  
Vol 20 (2) ◽  
pp. 167-174
Author(s):  
Ilo Dicko ◽  
Yaya Ibrahim Coulibaly ◽  
Modibo Sangaré ◽  
Bismark Sarfo ◽  
Priscillia Awo Nortey

Background: Lymphatic filariasis (LF) is a parasitic disease that has been targeted for elimination through the Mass Drug Administration (MDA.) Although the MDA started in the Ankobra community in Ghana in 2000, LF prevalence as reported in 2014 was relatively high (4.5%). Non-compliance to the MDA has been associated with the persistent LF prevalence in endemic regions. Objective: This study determined the factors associated with the non-compliance to the MDA among patients living in the Ankobra community, Ghana. Methods: A cross-sectional study using a one-stage cluster sampling method was used to collect data between June and July, 2017 in Ankobra. Questionnaires were used to collect data from health workers, the MDA drug distributors and study participants in Ankobra. Data analysis was performed using STATA 14. Logistic regression was used to measure the degree of association between the dependent (non-compliance) and independent variables. Non-compliance rate was defined as the percentage of individuals who self-reported that they did not actually swallow the drugs provided during the MDA. Results: The MDA coverage and non-compliance rates were 73.5% (147/200) and 33.33% (49/147) respectively. The main reason for non-compliance was fear of drug adverse events (75.51%, 37/49). Thought of “not being susceptible to LF” was significantly associated with the non-compliance (aOR= 2.83, [CI= 1.15, 6.98]). Conclusion: Health education about the susceptibility of residents getting LF disease in endemic community must be intensified to improve compliance to MDA medication ingestion and thus meet the Global Elimination of Lymphatic Filariasis by 2020.


Author(s):  
Ram Kumar Panika ◽  
Rupesh Sahu

Background: Lymphatic filariasis is the second leading cause of disability worldwide accounting for more than 5 million disability adjusted life years annually. It has been a major public health problem in India which leads to irreversible chronic manifestations which are responsible for considerable economic loss and severe physical disability to the affected individuals. Mass drug administration (MDA) means administration of diethylcarbamazine and albendazole tablets to all people (excluding children <2 years, pregnant women, seriously ill persons) in endemic areas once in a year. The objective of the study was to assess coverage, compliance of MDA and awareness about lymphatic filariasis in Tikamgarh district of Madhya Pradesh.Methods: Cross-sectional study was conducted and total 120 households were surveyed in four randomly selected clusters of Tikamgarh district of Madhya Pradesh.Results: Out of total 743 persons 678 (91.25%) persons were eligible for MDA. Coverage rate was 86.57% and compliance rate was 74.27%. The main reason for non-compliance was not having the concerned disease (55.78%) followed by fear of side effect (22.31%). Only 40.83% among the surveyed families were aware about MDA and only 45.83% respondents had heard about lymphatic filariasis.Conclusions: There is coverage and compliance gap and awareness about the lymphatic filariasis and MDA program is limited. Drug compliance need to be improved and awareness need to be raised. MDA program should not be confined to tablet distribution only and due importance should be given to compliance rate.


Author(s):  
Ram K. Panika ◽  
Rakesh K. Mahore

Background: Lymphatic filariasis is a vector borne parasitic disease caused by lymphatic dwelling nematode parasite. It is one of the world's leading causes of permanent and long-term disability with an estimated 5.1 million disability adjusted life years (DALYs) are lost due to this disease. The National Health Policy 2002 aims at Elimination of Lymphatic filariasis by 2015 through Annual Mass Drug Administration (MDA) of single dose of DEC. Objective was to assess coverage and compliance of MDA Program and awareness about lymphatic filariasis in Chhatarpur district of Madhya Pradesh.Methods: Cross-sectional Study was conducted. Total 120 households were surveyed in four selected clusters of Chhatarpur district of MP.Results: Out of total 835 persons only 94.37% persons were eligible and 47 (5.62%) were not eligible for MDA for MDA. Coverage rate was 90.22% and compliance rate was 75.24%. The main reason for non-compliance was not having the concerned disease 34.38 % followed by fear of side effect (24.90%). Only 37.5% among the surveyed families were aware about MDA. Majority of respondent 21 (46.66%) acquired knowledge from health workers.Conclusions: The compliance of MDA program was low and the awareness about the lymphatic filariasis in the study population was limited in Chhatarpur district. Poor compliance of MDA is attributed to inadequate consumption of drugs due to poor awareness among eligible population. For elimination of lymphatic filariasis active involvement of community is very essential. It can be made possible through behavior change communication and health education of people.


Author(s):  
Santraj Ram ◽  
Shiv Prakash ◽  
Richa Singh ◽  
Gyan Prakash ◽  
Deepak Anand

Background: Lymphatic filariasis is one of the six infectious diseases identified by the International Task Force for Disease Eradication as “eradicable” or “potentially eradicable. It is estimated that, to interrupt transmission of lymphatic filariasis, MDA compliance must exceed 65–75%. This study was conducted to assess coverage and compliance of mass drug administration for lymphatic filariasis in Prayagraj District.Methods: This was a pre-tested, questionnaire based cross-sectional study. The study subjects (508) were selected randomly from rural (clusters of three villages) and urban (cluster of one ward) area of Prayagraj, Uttar Pradesh. Data was analyzed by using software SPSS version 23.0 and Chi-square test was used to test the association between the different variables. p-value less than 0.05 was considered as significant.Results: The overall coverage rate, compliance rate, coverage-compliance gap and effective coverage rate of study population (eligible for MDA) in Prayagraj District were 69.94%, 84.19%, 15.81% and 58.88% respectively. The coverage rate and effective coverage rate were 78.71% and 64.85% respectively among urban area as well as 66.99% and 56.88% respectively among rural area.Conclusions: The coverage rate and effective coverage rate were higher among population in urban area as compared to rural area while compliance rate was lower and hence coverage-compliance gap was higher among population in urban area as compared to rural area. The most common reason for not consuming drugs was ‘drugs not delivered by drug distributors’ (73.11%).


2014 ◽  
Vol 40 (1) ◽  
pp. 34-40 ◽  
Author(s):  
Ram Kumar Adhikari ◽  
Jeevan Bahadur Sherchand ◽  
Shiva Raj Mishra ◽  
Kamal Ranabhat ◽  
Rajendra Raj Wagle

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Benjamin F. R. Dickson ◽  
Patricia M. Graves ◽  
Ni Ni Aye ◽  
Thet Wai Nwe ◽  
Tint Wai ◽  
...  

Abstract Background Myanmar commenced a lymphatic filariasis (LF) elimination programme in 2000. Whilst the country has made considerable progress since then, a number of districts have demonstrated persistent transmission after many rounds of mass drug administration (MDA). The causes of unsuccessful MDA have been examined elsewhere; however, there remains little information on the factors that contribute in Myanmar. Methods We conducted an analysis of factors associated with persistent infection, LF-related hydrocoele and MDA participation in an area with ongoing transmission in 2015. A cross-sectional household survey was undertaken in 24 villages across four townships of Mandalay Region. Participants were screened for circulating filarial antigen (CFA) using immunochromatographic tests and, if positive, for microfilaria by night-time thick blood slide. Individuals 15 year and older were assessed for filariasis morbidity (lymphoedema and, if male, hydrocoele) by ultrasound-assisted clinical examination. A pre-coded questionnaire was used to assess risk factors for LF and for non-participation (never taking MDA). Significant variables identified in univariate analyses were included in separate step-wise multivariate logistic regressions for each outcome. Results After adjustment for covariates and survey design, being CFA positive was significantly associated with age [odds ratio (OR) 1.03, 95% CI 1.01–1.06), per year], male gender (OR 3.14, 1.27–7.76), elevation (OR 0.96, 0.94–0.99, per metre) and the density of people per household room (OR 1.59, 1.31–1.92). LF-related hydrocoele was associated with age (OR 1.06, 1.03–1.09, per year) and residing in Amarapura Township (OR 8.93, 1.37–58.32). Never taking MDA was associated with male gender [OR 6.89 (2.13–22.28)] and age, particularly in females, with a significant interaction term. Overall, compared to those aged 30–44 years, the proportion never taking MDA was higher in all age groups (OR highest in those < 5 years and > 60 years, ranging from 3.37 to 12.82). Never taking MDA was also associated with residing in Amarapura township (OR 2.48, 1.15–5.31), moving to one’s current village from another (OR 2.62, 1.12–6.11) and ever having declined medication (OR 11.82, 4.25–32.91). Decreased likelihood of never taking MDA was associated with a higher proportion of household members being present during the last MDA round (OR 0.16, 0.03–0.74) and the number visits by the MDA programme (OR 0.69, 0.48–1.00). Conclusions These results contribute to the understanding of LF and MDA participation-related risk factors and will assist Myanmar to improve its elimination and morbidity management programmes.


2021 ◽  
Vol 8 (11) ◽  
pp. 364-369
Author(s):  
Vikas Oraon ◽  
Vidushi Topno

Lymphatic filariasis is a mosquito born disease infecting over 120 million people globally. This is a community based cross-sectional study done to assess the prevalence of disease in Dumka District of Jharkhand. Three years data (2018-2020) were used to know the disease spectrum in this region. The disease mostly presented itself in its chronic forms. Prevalence of the disease has decreased in three years duration. Lymphedema cases were predominant as it was seen in both male and female. The study showed Lymphedema cases as 52% in 2018, 88% in 2019 and 98% in 2020. Overall disease is significantly higher in males than in female. But, Elephantiasis is more frequent in females. Present study reveals that there is remarkable impact of ELF program showing significant reduction in number of cases in three years duration. But the study indicates that the disease still continues to be the major cause of disability and poverty. Keywords: Lymphatic filariasis, Mass drug administration, Elimination of Lymphatic Filariasis.


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