scholarly journals Prevalence of urinary tract infection in febrile children of less than five years of age

2021 ◽  
Vol 7 (4) ◽  
pp. 205-211
Author(s):  
Mahishma K ◽  
Anil Kumar K

To determine the prevalence of urinary tract infection in febrile children, less than 5 years of age. To assess the validity of microscopic urine analysis and urine culture in the diagnosis of urinary tract infection.Prospective study. Children attending   the department of paediatrics, Dr.V.R.K. Women’s Medical College, Teaching Hospital & Research Centre, with febrile illness during June 2019-June 2020.370 children between 1 month to 5 years of age.Data related to age, sex, nutritional status, socioeconomic status and predisposing risk factors like urethral instrumentation, bowel habits etc, were noted. A thorough physical examination with relevant investigations were carried out in all these patients. Routine urinary microscopy was done in all patients and urine culture was done in those who showed pyuria of >5 pus cells/HPF in centrifuged urine sample.In our study, overall prevalence of UTI was 3.5% in children between 1 month to 5 yrs and 4.1% in children <2yrs and 7% in Children <1 year of age with M:F ratio of 1:1in children <2yrs. Prevalence of culture positivity was 44% in those who showed >10 pus cells/HPF in centrifuged sample of urine and 2.5% in those who showed >5pus cells/HPF.The presence of obvious source of fever such as upper respiratory tract infection or otitis media is not reliable in excluding urinary tract infection. Overall prevalence of UTI in our study was low (3.5%) and prevalence among children <2yrs was 4.1% and <1 year of age was 7%. Pyuria of >5pus cells/HPF (centrifuged urine sample) should be considered as significant and further evaluation should be done to initiate prompt treatment.

2017 ◽  
Vol 2 (1) ◽  
pp. 134-137 ◽  
Author(s):  
Binita Pradhan ◽  
SB Pradhan

IntroductionIn developing countries, urinary tract infections (UTIs) are one of the most commonly diagnosed diseases among the patient seeking medical service and being treated with empirical antibiotics which causes resistance.ObjectiveTo find out the prevalence of urinary tract infection and sensitivity pattern of antibiotics among bacterial pathogens isolated in patients attending Kathmandu Medical College Teaching Hospital, Duwakot.MethodologyAll the patients with the clinical suspicion of UTI were sent for urine culture. Prevalence of UTI and urinary pathogens isolated with antimicrobial profile was correlated.ResultA total number of 1735 clinically suspected as UTI cases were sent for urine culture sensitivity. Total culture positive were 239 (13.8%). The majority of isolates were from female patients comprising 180 (75%). The most common pathogenic microorganism isolated was E.coli (79.1%). Second most common organism was Klebsiella (11.7%) followed by Citrobacter (3.34%) and Proteus (2.92%). The isolated microorganism showed maximum number of sensitivity with the antibiotics Ofloxacin and Ciprofloxacin. The isolated microorganism demonstrated resistance with Nalidixic Acid and Co-Trimoxazole. ConclusionUrinary tract infection is a commonly encountered case in general practice. Females are commonly affected than men. The microbiological profile and the antibiotic sensitivity pattern while initiating empirical treatment must be taken into account while planning for the management. Regular supervision of the sensitivity pattern of pathogenic microorganism is mandatory for effective treatment.Birat Journal of Health Sciences Vol.2/No.1/Issue 2/ Jan - April 2017, Page: 134-137


Open Medicine ◽  
2013 ◽  
Vol 8 (5) ◽  
pp. 597-599 ◽  
Author(s):  
Tsuneaki Kenzaka ◽  
Ayako Kumabe ◽  
Yuka Urushibara ◽  
Kensuke Minami ◽  
Takeshi Ishida

AbstractA 93-year-old woman with neurogenic bladder was admitted to our hospital because of impaired consciousness. Her urine culture revealed urease-test-positive Corynebacterium urealyticum. She was diagnosed with hyperammonemia due to an obstructive urinary tract infection that was caused by urease-producing bacteria. The patient showed rapid improvement of impaired consciousness and hyperammonemia after urine analysis. It is necessary to consider obstructive urinary tract infection as a differential diagnosis of hyperammonemia, which commonly occurs in urinary tract infections owing to the presence of urease-producing bacteria. Relief from obstruction is the most important treatment for hyperammonemia caused by this mechanism.


2019 ◽  
Vol 9 (4) ◽  
pp. 18-23
Author(s):  
Arun Sedhain ◽  
Abja Sapkota ◽  
Bidhan Shrestha

Background: Urinary tract infection (UTI) is characterized by pathological invasion of the urinary tract by microorganisms. Majorities of organisms causing UTI are gram negative bacteria, most common of which is E. coli. Urine culture and sensitivity test is used to isolate the organism and to identify the susceptible drug of choice for appropriate treatment. This hospital-based study was carried out to analyze the spectrum and antibiotic susceptibility of microorganisms causing UTI. Methods: A retrospective study was done to analyze the results of urine culture and sensitivity test done at Chitwan Medical College Teaching Hospital over a period of two and half years. Standard guideline and protocol were used to collect the urine sample and to perform the test. Data analysis was done using SPSS version 21.0. Result: Out of 12, 925 urine samples submitted for culture and sensitivity test during the study period, bacterial pathogens were isolated from 3, 173 (24.54%) samples, which was significantly higher among females (28%) than the males (17%). The most common organism isolated on the culture was E. coli (68.5%) followed by Klebsiella (18.4%). Sensitivity of the uropathogens was seen highest with colistin (79.2%) followed by teicoplanin (64.58%), Aztreonam (63.25%) and Ni­trofurantoin (61.16%). Most common antibiotics that showed resistance to the microorganisms in this study were Ampicillin (60.93%), Cotrimoxazole (53.72%), Cefixime (40.57%) and Levofloxacin (32.93%). Conclusions: This study has found a usual pattern of UTI with higher prevalence among females and E. coli being the most common organism. Nitrofurantoin has been found to have a good sus­ceptibility for the treatment of UTI.


Author(s):  
Rini Riyanti ◽  
Prihatini Prihatini ◽  
M.Y Probohoesodo

Urinary tract infection diagnosis is based on urine culture, taken from a midstream collection in the morning. Obtaining samplesin this manner is difficult in children less than 3 years. In children less than 3 years, urine is obtained by urine collectors. Using urinecollectors may cause discomfort, and the possibility that the urine collectors may not adhere resulting in contamination. (1) Developinga practical method for urine sample collection. (2) Comparing culture from diapers and urine collectors samples. (3) Knowing the limittime for using diapers acceptable for urine culture. Urine samples were obtained from 20 children less than 3 years, using urine collectorsand diapers used for 1 hour, 2 hours and 3 hours and then cultured. Majority of the urine culture from diapers used for 1 hour and 2hours showed the same result with the urine culture from urine collectors. Contamination was found in the urine culture result fromdiapers used for 3 hours. Urine samples from diapers used for 1 hour and 2 hours can be used as samples for urine culture. The techniqueis easy and can be done in children less than 3 years.


2007 ◽  
Vol 43 (1) ◽  
pp. 61-64 ◽  
Author(s):  
Michelle Puskar ◽  
Carol Lemons ◽  
Mark G. Papich ◽  
Shelley L. Vaden ◽  
Adam Birkenheuer

A 10-year-old, castrated male, domestic longhaired cat with a history of urinary tract disease and perineal urethrostomy was presented for evaluation of persistent urinary tract inflammation. Prior to referral, diphtheroid organisms had been cultured from a urine sample obtained by cystocentesis, and they were interpreted as sample contamination. Subsequent urine culture and gene sequencing identified Corynebacterium jeikeium, which was resistant to antibiotics and appeared to be the cause of the urinary tract infection.


2020 ◽  
Vol 5 (2) ◽  
pp. 1011-1015
Author(s):  
Bijoylakshmi Dewasy ◽  
Randhir Kumar Singh ◽  
Surya Bahadur Parajuli ◽  
Tara Kafle ◽  
Anjali Mishra

Introduction Urinary tract infection (UTI) is a frequent condition encountered in clinical settings. Empirical treatment is common. The treatment without urine culture and sensitivity leads to antimicrobial resistance. This is a major global concern. Objective The objective of this study was to find the prevalence and susceptibility pattern of Bacterial Uropathogens among patients with Urinary Tract Infection at Birat Medical College and Teaching Hospital of eastern Nepal. Methodology A cross-sectional study was conducted among patients with UTI attending Birat Medical College and Teaching Hospital from August 2018 to December 2018. The sample size of the study was 530. Ethical clearance was taken from the Institutional Review Committee of Birat Medical College and Teaching Hospital (Ref: IRC-PA-009/2075-76). Data were entered into Microsoft Excel and analyzed by using SPSS. Results The prevalence of bacterial uropathogens among urine culture was 66.04%. The common uropathogens isolated were E.coli (66.9%) and Klebsiella spp (15.1%). E.coli was highly susceptible to Chloramphenicol (100%) followed by Ceftrixone (82.4%), Cefpodoxime (77.8%) and Amikacin (77.9%); while Klebsiella spp were susceptible to nalidixic acid (40%) followed by co-trimoxazole (17.9%). Conclusion Almost 2 out of 3 samples had bacterial uropathogens isolated. E. coli and Klebsiella spp were common. Chloramphenicol and Nalidixic acid were highly susceptible to E.coli and Klebsiella spp respectively.


2019 ◽  
Vol 6 (6) ◽  
pp. 2459
Author(s):  
Pondugala Sunil Kumar ◽  
Dinendraram Ketireddi

Background: Children with fever comprise a major proportion of our practice in outpatient department of Paediatric. Among the fever cases Urinary tract infection is the third most common cause of febrile illness in children. The emphasis on identification of urinary tract infections in febrile children is minimal. Very often, children receive antibiotics empirically, without any adequate evaluation for urinary tract infection. The objective of our study is to determine the prevalence of urinary tract infection in all febrile children from 1months to 5 years of age.Methods: A prospective study was undertaken in the department of Pediatrics, Government medical college, Srikakulam. Urine was collected from enrolled febrile patients and sent for routine microscopic examination as well as for culture and sensitivity.Results: The study included 500 children. Females were 256(51.2%) and males were 244(48.8%). The total prevalence of UTI cases were 6%. The incidence in <1 year was 7.05%, 1-2 years was 5.97 % and >2 years was 5.35%. The prevalence of UTI was higher among females (7.68%) than males (4.68%). Apart from fever, the commonest symptoms were dysuria, abdominal pain, vomiting, chills and rigors and loss of appetite. Urine culture shows E. coli followed by Klebsiella were found to contribute the maximum number of cases.Conclusions: Possibility of Urinary Tract Infection must be considered in all febrile children and urine culture specimen must be collected as a part of diagnostic evaluation.


2014 ◽  
Vol 2 (1) ◽  
Author(s):  
G Somaiah ◽  
Ashraf Mohinuddin Siddique ◽  
Suaraj Gupte ◽  
Sai Kiran ◽  
B Raj Kumar ◽  
...  

The aim of the present study was to diagnose the urinary tract infection in febrile children and to assess the validity of microscopic urine analysis and urine culture in the diagnosis of UTI. It is a prospective study conducted in a tertiary care hospital. 370 children were included in the study, data related to age, sex, nutritional status, socioeconomic status and predisposing risk factors like urethral instrumentation, bowel habits etc, were noted. A thorough physical examination with relevant investigations was carried out in all patients. Routine blood counts, urine analysis was done and those showing pus cells >5 per HPF in centrifuged urine sample were taken as study group and urine culture sensitivity was done in them. A total of 370 febrile children were included in the study, out of 370 patients in study 165 were males and 205 were females with M: F ratio 1:1.2 and majority of them i.e.64.8% were <2years. In our study out of 370 children 48 children showed significant pyuria(12.9%) of pyuric cases 26% showed significant bacterial growth making an overall prevalence of 3.5%.Among culture positive UTI'S 76% were <2years of age with a overall prevalence of 4.1% in children <2years and 7%in children <1year.


2018 ◽  
Vol 5 (2) ◽  
pp. 359
Author(s):  
Shaik Ateal Saheb

Background: In children less than five years of age, fever is the most common reason to visit emergency/outpatient pediatric departments. Quite often, the child receives antibiotics empirically, without adequate evaluation for urinary tract infection. The objectives of this study were to evaluate the prevalence of urinary tract infection (UTI) in febrile children, less than 59 months of age.Methods: Records of 370 children between 1 to 59 months of age, attending the department of paediatrics with febrile illness were reviewed. Data related to age, gender, socioeconomic status, nutritional status, clinical diagnosis, abdominal ultrasound, urinary microscopy and urine culture were analysed.Results: Records of 370 children were evaluated, among them, 240/370 (64.86%) children were below two years, and 130/370 (35.13%) were above two years. 165/370 (44.6%) were males, and 205/370 (55.4%) were females. The overall occurrence of urinary tract infection as defined by significant pyuria was 48/370 (12.9%) in children less than five years of age. The prevalence of UTI in children less than one year of age was 26/370 (7%), whereas it was 15/370 (4 %) in less than two years of age and 7/370 (1.8%) between two to five years. Among pyuric patients, 13/48 (27%) had a urine culture positive reports. The positive urine culture was seen in 6/13 (46%) of children with pus cells> 5/HPF and remaining 7/13 (54%) in children with pus cells >10/HPF. E. coli was the predominantly [9/13 (69%)] seen organism in urine cultures.Conclusions: In present study, the overall occurrence of UTI in children less than five years was 13%. Only 3.5% of children had culture-positive UTI. 46% of positive cultures were found in children having urine pus cells > five /HPF in the centrifuged sample, it is recommendable that children with pyuria should be evaluated thoroughly to initiate prompt treatment and have a successful outcome. 


2021 ◽  
Vol 15 (12) ◽  
pp. 3494-3497
Author(s):  
Akhtar Ali ◽  
Shahzad Ali ◽  
Naresh Kumar Valecha ◽  
Saeed Ahmed Khan

Background: Urinary tract infections (UTI) are one of common clinical condition encountered in various clinical settings. This the most common infection, typically diagnosed on the basis history and clinical examination endorsed by urine analysis and culture sensitivity. Timely diagnosis and treatment are crucial in management. For diagnosis of UTI, Urine culture is standard, as it provide detail information for urinary pathogens, but it has certain disadvantages e.g. urine culture is costly, takes longer time, and up to 60-80% of the results are negative. Objective: To determine the diagnostic accuracy of urinalysis (Urine DR) in detection of urinary tract infection (UTI) among suspected cases of UTI by taking urine culture as gold standard. Materials And Methods: This cross sectional study was conducted at study was conducted at Department of Urology, Jinnah Postgraduate Medical Centre (JPMC) Karachi, from march 2021 to September 2021. All patients who visited to JPMC Karachi and fulfilled the inclusion criteria and were included in the study after getting Informed consent. All patients were evaluated by urinalysis and urine culture. The results of urinalyses were recorded and compared with the results obtained on subsequent urine cultures. All of the specimens were obtained by the “clean-catch” method. All data and results were recorded on proforma and used electronically for research purpose. Results: Mean ± SD of age was 52.6±8.5 years. In distribution of gender, 60 (53.1%) patients were male while 53 (46.9%) were female patients. Diagnostic accuracy of urinalysis was 73.45% in diagnosis of urinary tract infection with sensitivity 76.47%, specificity 72.15% PPV 54.17% and NPV was found to be 87.69% by using urine culture findings as gold standard. Conclusion: It is to be concluded that evaluating of urinary tract infection (UTI) with urinalysis (Urine DR) did not prove helpful and comparable to urine culture. Urine culture should be done in each and every suspected case of UTI. Keywords: Bacteriuria, Diagnostic Accuracy, Sensitivity, Specificity, Urinalysis


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