scholarly journals Monoclonal antibodies for cancerous conditions in essential medicine list: An experience from a tertiary hospital in Bengaluru, India

2021 ◽  
Vol 8 (2) ◽  
pp. 156-160
Author(s):  
Prasad Byrav D S ◽  
Sharath Burugina Nagaraja ◽  
Niveditha
Keyword(s):  
Monoclonal Antibody ◽  
Monoclonal Antibodies ◽  
Essential Medicine ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Average Dose ◽  
Essential Drug ◽  
Essential Drug List ◽  
Drug List ◽  
Average Total Number

Globally, cancer is emerging as a major public health problem. Monoclonal antibodies are extensively used for cancerous conditions at tertiary hospitals. Many of these are not easily available for patients seeking treatment from public sector. It is difficult for poor patients to afford these drugs on individual basis.The aim of our study is to calculate the prescribed daily dose of monoclonal antibody in cancerous conditions, to know the number of monoclonal antibody present in the essential drug list and to know the average total number of drugs prescribed in generic names. The average dose of the monoclonal antibody used is calculated and the common conditions for which it is used is tabulated and the drug usage is noted for both genders. The number monoclonal antibody present in the list of essential medicine of India and WHO is compared. The average total number of drugs prescribed in generic names is calculated.Average prescribed dose calculated was 382 mg for Trastuzumab, 455mg for rituximab. Only a few monoclonal antibodies were found in who essential drug. Only Trastuzumab and rituximab monoclonal antibody were found in the essential drug list of India. While, Trastuzumab is the most commonly (61%) prescribed drug in the generic form. The study concludes that Trastuzumab is the commonly used monoclonal antibody followed by Rituximab and Bevacizumab. Only Trastuzumab and rituximab were found in Indian essential drug list. Measures for Inclusion of other monoclonal anti bodies can be made by the policy decisions.

scholarly journals Prescribing pattern of antidepressant drugs in two teaching hospitals in Bangladesh

Mediscope ◽  
2019 ◽  
Vol 6 (2) ◽  
pp. 53-58
Author(s):  
Baishakhi Islam ◽  
Iram Shahriar ◽  
Tamanna Jannat
Keyword(s):  
Antidepressant Drugs ◽  
Public Health Problem ◽  
Teaching Hospitals ◽  
Major Public Health Problem ◽  
Essential Drug ◽  
Prescribing Pattern ◽  
Prescribing Indicators ◽  
Medical College ◽  
Essential Drug List ◽  
Drug List

As depression is a major public health problem, a drug utilization study is beneficial in clinical practice for rational prescribing and helpful for minimizing the medication errors. In our country antidepressant drugs are commonly used in treatment of depression. To obtain information regarding the prescribing pattern of antidepressant drugs in accordance with WHO prescribing indicators, a descriptive cross sectional study was carried out at psychiatry out-patient department of Sir Salimullah Medical College & Hospital(SSMCH) and Dhaka Medical College Hospital(DMCH) in Bangladesh. A total of 300 (150 in each hospital) prescriptions were analyzed by using WHO prescribing indicators and Essential Drug List of Bangladesh. Among 300 patients with major depression (64%, 58.66%), females were(53.33%, 58%) and males were (46.67%, 42%) which is commonly seen between the age group 18-27 years in DMCH and SSMCH respectively. Most commonly prescribed antidepressant as monotherapy was sertraline (58.02%, 70%). Average number of drugs per prescription was (2.24 ± 0.93, 2.12 ± 0.83). Percentage of drug prescribed by generic name and percentage of encounters with an injection prescribed was nil in both hospitals. Percentage of drugs prescribed from Essential Drug List of Bangladesh was (37.5%, 25.47%) in DMCH and SSMCH respectively. Prescribing pattern of antidepressant drugs in both teaching hospitals are almost similar in accordance with WHO prescribing indicators. Mediscope Vol. 6, No. 2: Jul 2019, Page 53-58

Recent study on safety monitoring herbal medicines of Thai National Essential Drug List (NEDL)

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
Y Oppamayun ◽  
W Rungapirumnan ◽  
W Suwanakaesawong ◽  
C Uerchaikul
Keyword(s):  
Herbal Medicines ◽  
Safety Monitoring ◽  
Essential Drug ◽  
Essential Drug List ◽  
Drug List

scholarly journals Evaluation of rational drug use pattern using WHO prescribing indicators in a medical intensive care unit of a tertiary teaching hospital in Kerala, India

2017 ◽  
Vol 6 (6) ◽  
pp. 1328
Author(s):  
Shobha P. ◽  
Messaline Sunitha
Keyword(s):  
Tertiary Care ◽  
Care Hospital ◽  
Prescribing Practices ◽  
Essential Drug ◽  
Prescribing Pattern ◽  
Respiratory Problems ◽  
Essential Drug List ◽  
Drug List ◽  
Tertiary Teaching ◽  
Set Up

Background: ICU patients are exposed to more number of life saving drugs and face drug related problems like therapeutic failure, drug interactions and frequent adverse drug reactions. The cost of ICU hospitalisation and money spent on medicines is also a huge burden on these patients. A study of prescribing pattern in an ICU set up will serve as a medical audit to monitor and evaluate the prescribing practices to make it more rational and cost effective.Methods: A prospective observational study was carried out in a medical ICU of a tertiary care hospital. All the inpatients admitted in the medical ICU during the study period of 2 months were included in the study. The data obtained from the case sheets were used to assess the prescribing pattern and rationality of drug use.Results: A total of 101 patients were admitted in 2 months. The most common illness for which the patients (22) were admitted was respiratory problems. Average number of drugs per prescription was 6.9. Cardiovascular system (23.9%) drugs were the most frequently prescribed. Pantoprazole (77) was the single most commonly prescribed drug. 40% of the drugs were prescribed from the essential drug list. The average cost of medicines incurred per person in our study was 5126.33 in INR.Conclusions: Polypharmacy and unwanted prescription of proton pump inhibitors can be avoided by prescribing more generics and drugs from essential drug list.

scholarly journals Assessment of veterinary drugs dispensing practices in veterinary clinics in Gondar town, North West Ethiopia: a cross sectional study

2021 ◽  
Vol 7 (8) ◽  
pp. 395
Author(s):  
Birhanu Berihun Kidanu ◽  
Dak Chuol Cay ◽  
Zemene Demelash Kifle
Keyword(s):  
Treatment Guideline ◽  
Continuous Medical Education ◽  
Veterinary Drug ◽  
Essential Drug ◽  
Cross Sectional ◽  
Veterinary Clinic ◽  
Essential Drug List ◽  
Drug List ◽  
Dispensing Practices ◽  
Gondar Town

<p class="abstract"><strong>Background:</strong> Dispensing practice plays a major role in the provision of rational drug therapy. This study aimed to assess the veterinary drug dispensing practice by pharmacists and other veterinarian assistance in veterinary clinic Gondar town.</p><p class="abstract"><strong>Methods:</strong> A cross-sectional prospective descriptive study was carried out in the OPD of three public veterinary clinics in Gondar town for three months. The health facility indicators were examined by ensuring the good dispensing practices in three veterinary clinic and availability of essential drug list.</p><p class="abstract"><strong>Results:</strong> The average consultation time was 13 min and 50 sec. The average dispensing time was 5 min and 3 sec calculated from 100 prescriptions. The percentage of drugs dispensed was 97.50% and percentage of drugs adequately labeled was high from the dispensed drugs (74.4%). The average patients with drug dosage knowledge were very low (25%). The result of the study revealed that the two veterinary clinic health facilities do not have any essential drug list. Out of three, one of them has a key drug from the WHO list 1 (30%) drug was available.</p><p class="abstract"><strong>Conclusions:</strong> The overall good dispensing practices at three veterinary clinics is low. Training, supportive supervision through continuous medical education, regular up-to-date medicine information and standard treatment guideline, and therapeutic audit are required for improvement of medicine use by prescriber and dispensers.</p>

scholarly journals Evaluation of Prescribing Pattern of the Private Practitioners in Bangladesh

2013 ◽  
Vol 7 (2) ◽  
pp. 51-53 ◽  
Author(s):  
Fouzia Begum ◽  
Md Royes Uddin ◽  
M M Shahin Ul Islam ◽  
Mst Nagnin Sarker ◽  
Rakhal Chandra Barman ◽  
...  
Keyword(s):  
Prescription Drugs ◽  
Prescribing Patterns ◽  
Dhaka City ◽  
Essential Drug ◽  
Prescribing Pattern ◽  
Private Practitioners ◽  
Essential Drug List ◽  
Medication Information ◽  
Drug List ◽  
Patient Medication

A prescription order is a written instruction of doctors to pharmacist to supply drugs in particular form to a patient and the directions to the patients regarding the use of medicines. This study was undertaken to observe the prescribing patterns of the private practitioners in Bangladesh, 430 prescriptions were collected randomly from Dhaka city and analyzed using WHO/INRUD indicators. There were average 3.40 drugs per prescription. Drugs were prescribed in generic name only in 0.20%. About 46.31% drugs were prescribed from the Essential Drug List, only 19% of prescriptions were complete in respect to patient medication information. Antibiotics were prescribed in 70.33% of the prescriptions; injections were prescribed in about 8.35% of the prescriptions. DOI: http://dx.doi.org/10.3329/fmcj.v7i2.13497 Faridpur Med. Coll. J. 2012;7(2): 51-53

scholarly journals Evaluating antimicrobial prescribing in a Tertiary Healthcare Institution in Nigeria

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Angus Nnamdi Oli ◽  
Nwanneka Onyeaso ◽  
Stephen Chijioke Emencheta ◽  
Chijioke M. Ofomata ◽  
James-Paul Kretchy ◽  
...  
Keyword(s):  
Anatomical Therapeutic Chemical ◽  
Defined Daily Dose ◽  
Essential Drug ◽  
Chi Square ◽  
Essential Drug List ◽  
Drug List ◽  
Daily Dose ◽  
Generic Prescribing ◽  
Tertiary Healthcare ◽  
Chi Square Test

Abstract Background Regular evaluation of antimicrobials prescriptions is important for optimal use. Objective This study determined the prescription patterns, class and costs of antimicrobials in the adult out-patient pharmacy of a Teaching Hospital in Nigeria. Methods A 1-year retrospective study from 1st January to 31st December 2018. The data, which included identification code, age, sex, antibiotics prescribed, number of antibiotics per prescription, number of medicines per prescription, dosage form, generic prescribing, drug on the essential drug list, and cost, were used in the analysis. The Chi-square test and Analysis of Variance were used to compare our data with the WHO–developed antimicrobial prescription Guidelines for Anatomical Therapeutic Chemical and Defined Daily Dose assignment of 2019. Results From 450 patient records, significantly more females (70%) were prescribed with antimicrobials (P = 0.0038). The prescription pattern showed that antimicrobials selection by class was significantly different (P < 0.0001) (top three being Amino-penicillin > Nitroimidazoles > Fluoroquinolone). In addition, age differed significantly (P < 0.0001) with 46–50 as the highest class. Dosage forms profile showed that the percentage of encounter with injections prescribed (1.8%) was less than WHO recommendation (13.4–24.1%). Most of the prescriptions (84.22%) were from the Essential Drug List. The average cost of prescriptions with two antimicrobials was the highest ($14.0807), then three ($10.7949), and one ($6.39858). The average number of drugs per prescription that had one (4.28), two (4.46), and three (5.55) antimicrobials, respectively, were more than double the average (2) recommended by WHO. Conclusion The study showed that most of the patterns are within limit, however, highlights the need for frequent evaluation.

scholarly journals Evaluation of prescribing patterns of medical practitioners in the state of Goa, India

2017 ◽  
Vol 6 (9) ◽  
pp. 2214
Author(s):  
Greeshma Upendra ◽  
Sushama A. Bhounsule
Keyword(s):  
Drug Interactions ◽  
Treatment Cost ◽  
The State ◽  
Prescribing Patterns ◽  
Essential Drug ◽  
Medical Practitioners ◽  
Inappropriate Use ◽  
Essential Drug List ◽  
Drug List ◽  
The Common

Background: According to WHO, worldwide more than 50% of all medicines are prescribed, dispensed, or sold inappropriately, while 50% of patients fail to take them correctly. Evaluating the prescribing patterns of the medical practitioners will throw light on the common types of irrational practices such as inappropriate use of antimicrobials, polypharmacy, over-use of injections, failure to prescribe according to clinical guidelines.Methods: 600 prescriptions prescribed by medical practitioners from March to April 2016 were analyzed using WHO prescribing indicators.Results: Out of the 1900 drugs prescribed, average number of drugs per prescription was 3.17. Total number of drugs prescribed by generic name was 11 (0.58%). An antibiotic was prescribed in 119 patients (19.83%). An injection was prescribed in 23 patients (3.8%). 567 drugs prescribed were from the essential drug list of India (29.8%).Conclusions: Polypharmacy increases the risk of drug interactions, treatment cost, decreases the patient’s compliance. Prescribing medicines by generic name avoids the confusion. By adhering to the national essential list of medicine, drugs will be available to the patients at all times and be cheaper.

Sign in / Sign up

Export Citation Format

Share Document