FISIOTERAPIA NA REABILITAÇÃO DE TENDINOPATIA DO CALCÂNEO: UMA REVISÃO

Aurea Gabriela Pereira Rodrigues; Gabriel Gomes Vilar de Sousa; Werena Lisboa de Jesus; Suellen Alessandra Soares de Moraes

doi:10.18310/2358-8306.v8n17.a14

FISIOTERAPIA NA REABILITAÇÃO DE TENDINOPATIA DO CALCÂNEO: UMA REVISÃO

CADERNOS DE EDUCAÇÃO SAÚDE E FISIOTERAPIA ◽

10.18310/2358-8306.v8n17.a14 ◽

2021 ◽

Vol 8 (17) ◽

Author(s):

Aurea Gabriela Pereira Rodrigues ◽

Gabriel Gomes Vilar de Sousa ◽

Werena Lisboa de Jesus ◽

Suellen Alessandra Soares de Moraes

Keyword(s):

Controlled Trial ◽

Trial Register

A tendinopatia do calcâneo (TC) é uma condição dolorosa e disfuncional, recorrente em indivíduos ativos e sedentários. A etiologia da TC é incerta, e tratamentos clínicos nem sempre são eficazes, o que merece atenção da comunidade científica quanto ao emprego racional de recursos terapêuticos com melhor evidência científica. A presente revisão objetivou descrever as principais abordagens fisioterapêuticas aplicadas no tratamento da TC. A busca dos artigos foi realizada entre janeiro e outubro de 2018 nas bases de dados PubMed, PEDro, Bireme e Cochrane Controlled Trial Register, limitada aos últimos cinco anos. Foram consideradas para esta revisão os artigos disponíveis na íntegra, em inglês, com Qualis de A1 até B2 na área de avaliação 21, e que utilizassem a fisioterapia como intervenção terapêutica. Foram excluídos artigos de metanálise e aqueles associados a mais de um tipo de intervenção sem os devidos controles. De 4.198 artigos, apenas 18 foram elegíveis, sendo 12 estudos experimentais em modelo animal e 6 ensaios clínicos. Os estudos experimentais mostraram vantagens na redução da dor e inflamação ao usar a fotobiomodulação como terapia única, bem como associado a outras terapias. Já a estimulação mecânica e a mobilização tecidual foram vantajosas quanto às propriedades biomecânicas e histológicas dos tendões lesionados. Nos ensaios clínicos, foram observadas melhorias nos escores de dor, mobilidade, função e força muscular em todas as abordagens terapêuticas, embora o exercício terapêutico excêntrico seja a abordagem mais recorrente. As abordagens fisioterapêuticas para o tratamento da TC com melhor evidência científica compreendem a fotobiomodulação e a estimulação mecânica por mobilizações e exercícios, sendo fortemente recomendadas para a prática clínica.

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Evaluation of a community-based mentoring program on psychosocial functioning of adolescents with a visual impairment: A randomized controlled trial

British Journal of Visual Impairment ◽

10.1177/0264619620935944 ◽

2020 ◽

pp. 026461962093594

Author(s):

Eline CM Heppe ◽

Agnes M Willemen ◽

Sabina Kef ◽

Carlo Schuengel

Keyword(s):

Visual Impairment ◽

Psychosocial Functioning ◽

Controlled Trial ◽

Mentoring Program ◽

Community Settings ◽

Community Based ◽

Youth Outcomes ◽

Randomized Controlled ◽

Trial Register ◽

The Impact

This study evaluated the efficacy of a mentoring program on improving psychosocial functioning of young people with a visual impairment (VI). Furthermore, the impact of experimentally matching mentees to mentors with or without VI on youth outcomes was examined. A total of 76 adolescents with VI (15–22 year; 46% boys) were randomized into a yearlong mentoring program ( n = 51) or care-as-usual ( n = 25). Mentoring involved one-on-one activities within community settings. Psychosocial functioning was improved in all participants during the study ( d = 0.35–1.06); however, mentoring outperformed care-as-usual only for autonomy (95% CI: 0.003, 0.31; d = 0.44) and competence satisfaction (95% CI: 0.02, 0.34; d = 0.55), and not for the other six psychosocial outcomes ( d < 0.36). Matching similarity was not significantly related to the outcomes assessed. Mentoring was of limited benefit for psychosocial functioning of youth with VI. This trial is registered in the Netherlands Trial Register NTR4768.

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High cereblon expression is associated with better survival in patients with newly diagnosed multiple myeloma treated with thalidomide maintenance

Blood ◽

10.1182/blood-2012-06-438101 ◽

2013 ◽

Vol 121 (4) ◽

pp. 624-627 ◽

Cited By ~ 78

Author(s):

Annemiek Broyl ◽

Rowan Kuiper ◽

Mark van Duin ◽

Bronno van der Holt ◽

Laila el Jarari ◽

...

Keyword(s):

Gene Expression ◽

Multiple Myeloma ◽

Clinical Efficacy ◽

Expression Profiling ◽

Controlled Trial ◽

Newly Diagnosed ◽

The European Union ◽

Free Survival ◽

Randomized Controlled ◽

Trial Register

Abstract Recently, cereblon (CRBN) expression was found to be essential for the activity of thalidomide and lenalidomide. In the present study, we investigated whether the clinical efficacy of thalidomide in multiple myeloma is associated with CRBN expression in myeloma cells. Patients with newly diagnosed multiple myeloma were included in the HOVON-65/GMMG-HD4 trial, in which postintensification treatment in 1 arm consisted of daily thalidomide (50 mg) for 2 years. Gene-expression profiling, determined at the start of the trial, was available for 96 patients who started thalidomide maintenance. In this patient set, increase of CRBN gene expression was significantly associated with longerprogression-free survival (P = .005). In contrast, no association between CRBN expression and survival was observed in the arm with bortezomib maintenance. We conclude that CRBN expression may be associated with the clinical efficacy of thalidomide. This trial has been registered at the Nederlands Trial Register (www.trialregister.nl) as NTR213; at the European Union Drug Regulating Authorities Clinical Trials (EudraCT) as 2004-000944-26; and at the International Standard Randomized Controlled Trial Number (ISRCTN) as 64455289.

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Treatment Fidelity Procedures for an Aphasia Intervention Within a Randomized Controlled Trial: Design, Feasibility, and Results

American Journal of Speech-Language Pathology ◽

10.1044/2019_ajslp-cac48-18-0227 ◽

2020 ◽

Vol 29 (1S) ◽

pp. 412-424

Author(s):

Elissa L. Conlon ◽

Emily J. Braun ◽

Edna M. Babbitt ◽

Leora R. Cherney

Keyword(s):

Randomized Controlled Trial ◽

Controlled Trial ◽

Treatment Protocol ◽

Treatment Fidelity ◽

Protocol Adherence ◽

Study Condition ◽

Randomized Controlled ◽

Aphasia Therapy ◽

Percent Accuracy ◽

Over Time

Purpose This study reports on the treatment fidelity procedures implemented during a 5-year randomized controlled trial comparing intensive and distributed comprehensive aphasia therapy. Specifically, the results of 1 treatment, verb network strengthening treatment (VNeST), are examined. Method Eight participants were recruited for each of 7 consecutive cohorts for a total of 56 participants. Participants completed 60 hr of aphasia therapy, including 15 hr of VNeST. Two experienced speech-language pathologists delivered the treatment. To promote treatment fidelity, the study team developed a detailed manual of procedures and fidelity checklists, completed role plays to standardize treatment administration, and video-recorded all treatment sessions for review. To assess protocol adherence during treatment delivery, trained research assistants not involved in the treatment reviewed video recordings of a subset of randomly selected VNeST treatment sessions and completed the fidelity checklists. This process was completed for 32 participants representing 2 early cohorts and 2 later cohorts, which allowed for measurement of protocol adherence over time. Percent accuracy of protocol adherence was calculated across clinicians, cohorts, and study condition (intensive vs. distributed therapy). Results The fidelity procedures were sufficient to promote and verify a high level of adherence to the treatment protocol across clinicians, cohorts, and study condition. Conclusion Treatment fidelity strategies and monitoring are feasible when incorporated into the study design. Treatment fidelity monitoring should be completed at regular intervals during the course of a study to ensure that high levels of protocol adherence are maintained over time and across conditions.

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Phonomotor Versus Semantic Feature Analysis Treatment for Anomia in 58 Persons With Aphasia: A Randomized Controlled Trial

Journal of Speech Language and Hearing Research ◽

10.1044/2019_jslhr-l-18-0257 ◽

2019 ◽

Vol 62 (12) ◽

pp. 4464-4482 ◽

Cited By ~ 9

Author(s):

Diane L. Kendall ◽

Megan Oelke Moldestad ◽

Wesley Allen ◽

Janaki Torrence ◽

Stephen E. Nadeau

Keyword(s):

Randomized Controlled Trial ◽

Response Latency ◽

Controlled Trial ◽

Semantic Knowledge ◽

Semantic Feature ◽

Feature Analysis ◽

Group Differences ◽

Randomized Controlled ◽

Confrontation Naming ◽

Semantic Feature Analysis

Purpose The ultimate goal of anomia treatment should be to achieve gains in exemplars trained in the therapy session, as well as generalization to untrained exemplars and contexts. The purpose of this study was to test the efficacy of phonomotor treatment, a treatment focusing on enhancement of phonological sequence knowledge, against semantic feature analysis (SFA), a lexical-semantic therapy that focuses on enhancement of semantic knowledge and is well known and commonly used to treat anomia in aphasia. Method In a between-groups randomized controlled trial, 58 persons with aphasia characterized by anomia and phonological dysfunction were randomized to receive 56–60 hr of intensively delivered treatment over 6 weeks with testing pretreatment, posttreatment, and 3 months posttreatment termination. Results There was no significant between-groups difference on the primary outcome measure (untrained nouns phonologically and semantically unrelated to each treatment) at 3 months posttreatment. Significant within-group immediately posttreatment acquisition effects for confrontation naming and response latency were observed for both groups. Treatment-specific generalization effects for confrontation naming were observed for both groups immediately and 3 months posttreatment; a significant decrease in response latency was observed at both time points for the SFA group only. Finally, significant within-group differences on the Comprehensive Aphasia Test–Disability Questionnaire ( Swinburn, Porter, & Howard, 2004 ) were observed both immediately and 3 months posttreatment for the SFA group, and significant within-group differences on the Functional Outcome Questionnaire ( Glueckauf et al., 2003 ) were found for both treatment groups 3 months posttreatment. Discussion Our results are consistent with those of prior studies that have shown that SFA treatment and phonomotor treatment generalize to untrained words that share features (semantic or phonological sequence, respectively) with the training set. However, they show that there is no significant generalization to untrained words that do not share semantic features or phonological sequence features.

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The Link Between Verbal Short-Term Memory and Anomia Treatment Gains

American Journal of Speech-Language Pathology ◽

10.1044/2019_ajslp-18-0176 ◽

2019 ◽

Vol 28 (3) ◽

pp. 1039-1052

Author(s):

Reva M. Zimmerman ◽

JoAnn P. Silkes ◽

Diane L. Kendall ◽

Irene Minkina

Keyword(s):

Short Term Memory ◽

Controlled Trial ◽

Treatment Success ◽

Linear Regression Models ◽

Language Performance ◽

Short Term ◽

Term Memory ◽

Treatment Gains ◽

Post Hoc

Purpose A significant relationship between verbal short-term memory (STM) and language performance in people with aphasia has been found across studies. However, very few studies have examined the predictive value of verbal STM in treatment outcomes. This study aims to determine if verbal STM can be used as a predictor of treatment success. Method Retrospective data from 25 people with aphasia in a larger randomized controlled trial of phonomotor treatment were analyzed. Digit and word spans from immediately pretreatment were run in multiple linear regression models to determine whether they predict magnitude of change from pre- to posttreatment and follow-up naming accuracy. Pretreatment, immediately posttreatment, and 3 months posttreatment digit and word span scores were compared to determine if they changed following a novel treatment approach. Results Verbal STM, as measured by digit and word spans, did not predict magnitude of change in naming accuracy from pre- to posttreatment nor from pretreatment to 3 months posttreatment. Furthermore, digit and word spans did not change from pre- to posttreatment or from pretreatment to 3 months posttreatment in the overall analysis. A post hoc analysis revealed that only the less impaired group showed significant changes in word span scores from pretreatment to 3 months posttreatment. Discussion The results suggest that digit and word spans do not predict treatment gains. In a less severe subsample of participants, digit and word span scores can change following phonomotor treatment; however, the overall results suggest that span scores may not change significantly. The implications of these findings are discussed within the broader purview of theoretical and empirical associations between aphasic language and verbal STM processing.

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