INTRADURAL EXTRAMEDULLARY SPINAL CORD TUMOURS- SURGICAL OUTCOME AT MAHATMA GANDHI HOSPITAL

2019 ◽  
Vol 6 (28) ◽  
pp. 1903-1906
Author(s):  
Aman Agarwal ◽  
Rohin Bhatia
2016 ◽  
Vol 9 (1) ◽  
pp. 11
Author(s):  
Md. Kamrul Ahsan ◽  
Md. Abdul Awwal ◽  
Shahidul Islam Khan ◽  
Md. Hamidul Haque ◽  
Naznin Zaman

<p><strong>Background:</strong> Intradural extramedullary spinal cord tumours (IESCT) accounts for approximately two thirds of all intraspinal neoplasm and are of important clinical consideration and surgery is the essence in cases with neurological deterioration.</p><p><strong>Objective:</strong> To share our experience on the outcome of surgical excision of intradural extramedullary spinal cord tumours. Methods: Results of 60 patients surgically treated intradural extramedullary spinal tumours between Octo­ber 2003 and October 2015 at Bangabandhu Sheikh Mujib Medical University and in our private settings, Dhaka, were analyzed retrospectively. There were 32 males, 28 females with an average age of 52.4 years (13-70 years) and followed up for at least a year. The preoperative symptom with duration, tumours location and intradural space occupancy and the histopathological diagnosis were analyzed. Pain was evaluated by the visual analogue scale (VAS) and the neurologic function was assessed by Nurick's grade.</p><p><strong>Results:</strong> The tumours were located as, thoracic 32 (53.33%), lumbar 16 (26.67%), cervical 04 (6.67%), and junctional 08 (13.33%), CervicoThoracic-01, Thoracolumbar-07). The histopathological diagnosis included schwannoma 35 (58.33%), meningiomas 14 (23.33%), neurofbroma 4 (6.67%), arachnoid cyst and myxopapillary ependymoma 03 (05.00%) each and paraganglioma 01 (01.67%). The VAS score was reduced in all cases from 8.0 ± 1.2 to 1.2 ± 0.8 (p &lt; 0.003) and the Nurick's grade was improved in all cases from 3.0 ± 1.3 to 1.0 ± 0.0 (p &lt; 0.005). The preoperative neurological deficit improved within 8 postoperative weeks in most cases and within 1 postoperative year in all cases. Complications included cerebrospinal fluid leakage, parasthesia, dependant bedsore 02 (3.33%) each and recurrence 03 (05.00%). and further neurological deterioration 1 (01.67%) case.</p><p><strong>Conclusion:</strong> lntradural extramedullary tumors detected by MRI are mostly benign and good clinical results can be obtained when treated surgi­cally. Aggressive surgical excision potentially minimizes neurologic morbidity and improved outcome. ­</p>


10.14444/8077 ◽  
2021 ◽  
pp. 8077
Author(s):  
Prashant Raj Singh ◽  
Tarun Kumar Pandey ◽  
Raghavendra Kumar Sharma ◽  
Faran Ahmad ◽  
Ankur Kumar ◽  
...  

2017 ◽  
Vol 5 (1) ◽  
pp. 2186-2190 ◽  
Author(s):  
Dr.Sandeep. Inchnalkar. ◽  
◽  
Dr.Kashif. Ansari. ◽  
Dr.Suraj. Mahadik. ◽  
Dr.Nikunj. Shekhada. ◽  
...  

2015 ◽  
Vol 61 (5) ◽  
pp. 333-338 ◽  
Author(s):  
M. Afathi ◽  
E. Peltier ◽  
T. Adetchessi ◽  
T. Graillon ◽  
H. Dufour ◽  
...  

2016 ◽  
Vol 30 (1) ◽  
pp. 106-112
Author(s):  
Mangal Govind ◽  
Mittal Radheyshyam ◽  
Sharma Achal ◽  
Gandhi Ashok

Abstract Introduction: Intradural extramedullary (IDEM) spinal cord tumours account two thirds of all intraspinal tumours. The objective of this study was to determine short- and long-term outcomes of surgical patients with IDEM spinal cord tumours, and to see clinical features that could be helpful in management of patients with these lesions (operated by single senior surgeononly). Methods: A retrospective review of 201 operative IDEM spinal cord tumours cases between 1993 and 2014 was performed. Outcomes were scored at one month and at mean follow-up of 8.5 months postoperatively. In addition, patient demographics, tumour types and locations were also collected. Statistical analysis was conducted utilizing Chi-square and Student's t-tests. Results: There were 93 men and 108 women (mean age 48 yrs, range 5-87 yrs). Men presented at a younger age than women (42 vs 51 yrs, P<0.02). 165 (82.08 %) patients presented with severe radiculopathy and myelopathy. The 36 (17.91 %) had symptoms of radiculopathy. Mean duration of symptoms prior to diagnosis was 11 months. Schwannomas (113 patients) had the longest mean duration of symptoms (14.9 months), followed by meningiomas (68 patients, 8.4 months), and ependymomas (20 patients, 2 months). Hundred and eighty nine (94%) of patients demonstrated significant improvement at one-month and 186 (92%) at 6-month mean follow-up. Only 39/201 (19.4%) patients had residual focal deficits on long term follow-up. Conclusions: Surgery for IDEM should be expected to produce significant and dramatic improvement in most of patients. Demographic, tumor-specific and anatomic considerations will be clinically useful while managing IDEM.


2021 ◽  
pp. 219256822098257
Author(s):  
Yoshihiro Matsumoto ◽  
Hirokazu Saiwai ◽  
Keiichiro Iida ◽  
Seiji Okada ◽  
Makoto Endo ◽  
...  

Study Design: Retrospective diagnostic analysis. Objectives: To establish a new predictor of surgical outcome after surgery for intradural extramedullary spinal tumor (IDEMT) in the thoracic spine, we introduced shape factor (SF), a mathematical description of the morphology of the spinal cord. SF was calculated by dividing object area by the square of perimeter. Materials and Methods: Forty-three consecutive patients with IDEMT, detected by magnetic resonance imaging at the thoracic level with myelopathic signs, were included. Preoperative transverse cross-sectional area (CSA) and perimeter of the spinal cord (perimeter) at the level of maximal compression were measured. SF was calculated as 4π × CSA/(perimeter)2. The association between clinicoradiological factors and surgical outcome of IDEMT was statistically analyzed. Results: Mean CSA, perimeter, and SF were 27.8 ± 15.8 mm2, 28.8 ± 6.1 mm, and 0.385 ± 0.14, respectively. A histogram distribution revealed that perimeter and SF, but not CSA, fit the normal distribution. The patients were subdivided into 2 groups according to postoperative modified Japanese Orthopedic Association Score (mJOA). [group F (favorable): n = 32, mJOA ≥ 9; group UF (unfavorable): n = 11, mJOA < 9). Group UF had significantly lower mean CSA and SF. In univariate analysis of possible predictive factors for IDEMT surgery, greater age, lower preoperative mJOA, and lower SF were significantly associated with unfavorable outcome. In multivariate analysis, lower SF was the only significant predictor of postoperative outcome (odds ratio = 2.66, 95% CI 1.10–6.39, p = 0.0115). Conclusion: Measurements of CSA and perimeter, followed by calculation of SF, may provide valuable quantitative information for the outcome of surgery for IDEMT.


2018 ◽  
Vol 16 (2) ◽  
pp. 274-274
Author(s):  
Simone E Dekker ◽  
Chad A Glenn ◽  
Thomas A Ostergard ◽  
Osmond C Wu ◽  
Fernando Alonso ◽  
...  

Abstract This 3-dimensional operative video illustrates resection of 2 cervical spine schwannomas in a 19-yr-old female with neurofibromatosis type 2. The patient presented with lower extremity hyperreflexity and hypertonicity. Magnetic resonance imaging (MRI) demonstrated 2 contrast-enhancing intradural extramedullary cervical spine lesions causing spinal cord compression at C4 and C5. The patient underwent a posterior cervical laminoplasty with a midline dural opening for tumor resection. Curvilinear spine cord compression is demonstrated in the operative video. After meticulous dissection, the tumors were resected without complication. The dural closure was performed in watertight fashion followed by laminoplasty using osteoplastic titanium miniplates and screws. Postoperative MRI demonstrated gross total resection with excellent decompression of the spinal cord. The postoperative course was uneventful. The natural history of this disease, treatment options, and potential complications are discussed.


2020 ◽  
Author(s):  
Kyle B Mueller ◽  
Jean-Marc Voyadzis

Abstract Spinal schwannomas most likely occur at the thoracic level and within the intradural extramedullary compartment. They are benign, typically slow-growing, peripheral nerve sheath tumors that produce symptoms by displacing or compressing the nerve roots and spinal cord. There is an association with patients that have neurofibromatosis type 2. Surgical pearls including the utilization of intraoperative ultrasound for localization, D wave monitoring, and microsurgical dissection are demonstrated. Pertinent high-yield radiographic and histological features of schwannomas are reviewed.1-4  We report the case of a 59-yr-old female who presented with progressively worsening gait instability that was associated with lower extremity numbness progressing to weakness. She had myelopathic findings on examination, which included brisk patellar reflexes and persistent clonus with sensory changes to the umbilicus and mild leg weakness. Full body examination revealed no stigmata of neurofibromatosis. Magnetic resonance imaging of the neuroaxis demonstrated a large, intradural extramedullary mass with peripheral enhancement that spanned the T9 to T11 vertebral levels with severe compression of the spinal cord. There were no intracranial, cervical, or lumbar findings. Surgical intervention was planned with the following objectives: decompression of the neural elements, curative resection, and diagnosis. Patient consent for the procedure was obtained. Institutional Review Board approval for solitary case reports are not needed at our institution.


2006 ◽  
Vol 64 (1) ◽  
pp. 149-152 ◽  
Author(s):  
José Fernando Guedes-Corrêa ◽  
Ricardo Caratta Macedo ◽  
Rafael Pereira Vaitsman ◽  
Jorge Gomes de Mattos ◽  
Jovita Marques Agra

Cysticercosis is an endemic condition in many developing countries. Although it is the most common parasitic disease of the central nervous system, cysticercal involvement of the spinal cord is rare. It may occur as intradural extramedullary, intramedullary, intramedullary associated with intradural-extramedullary or as the vertebral presentation. We report the case of a 53-year-old woman who presented with low back pain of acute onset and no other symptoms. Magnetic resonance imaging (MRI) showed an intramedullary cyst of the conus medullaris region which, at pathological examination, was diagnosed as a cysticercal cyst. She refused anticysticercal agents and steroids postoperatively. After an eight-year follow-up, the patient performs the activities of her daily living with no difficulties, and annual spinal MRIs show no residual signs of the disease. Clinical, pathofisiological, diagnostic and therapeutic aspects of spinal cord intramedullary cysticercosis are discussed.


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