scholarly journals Influence of Negative Calorie Foods on Atherogenic Indices in Overweight Women

2020 ◽  
Author(s):  
Mohammadreza Rezaeipour
Keyword(s):  
Weight Loss ◽  
P Value ◽  
Group Comparison ◽  
Dietary Regimen ◽  
Overweight Women ◽  
Healthy Choice ◽  
Atherogenic Lipid Profile ◽  
Atherogenic Indices ◽  
Caloric Requirements ◽  
Atherogenic Lipid

Objective: The present study aimed to determine the effects of diet of negative calorie foods (NCF) on weight, atherogenic lipids, and atherogenic ratio and compare its efficiency with diet of low calorie foods (LCF). Materials and Methods: In this randomized clinical trial, the participants were randomly selected from inactive overweight females (age 45-75 years) by parallel assignment were distributed randomly into two groups: NCF group that received a highcarbohydrate (75%), and low-fat (10%) diet, and LCF group had a dietary recipe with 55% of carbohydrate and a little fat (30%) content. Both groups had a healthy calorie restriction (15%) from their daily caloric requirements within three months. Evaluation of body weight, atherogenic lipids (total-C, HDL-C and LDL-C), and atherogenic ratio (total-C to HDL-C) were performed pre- and postintervention for all subjects and compared to each other. Results: The results of the within-group comparison of NCF and LCF on weight (respectively, P -value= 0.04; P -value= 0.03), total-C (respectively, P -value= 0.02; P -value= 0.03), HDL-C (respectively, P -value= 0.04; P -value= 0.01) and LDL-C (respectively, P -value= 0.01; P -value= 0.03) revealed significant effects. Also, significant differences were observed between groups in atherogenic lipid profile, total-C ( P -value: 0.03), HDL-C ( P -value: 0.001), and LDL-C ( P -value: 0.03). The result of the between-group comparison was also significant in atherogenic ratio ( P -value: 0.04). Conclusion: Contrary to expectation, dietary regimen demonstrated a similar pattern of weight loss in females. The NCF when compared to the LCF, is not a healthy choice for weight loss in sedentary females with overweight.

38-LB: Reduced Carbohydrate and Increased Protein and Fat during Weight Loss Improve the Atherogenic Lipid Profile in Type 2 Diabetes

Diabetes ◽  
2021 ◽  
Vol 70 (Supplement 1) ◽  
pp. 38-LB
Author(s):  
MADS N. THOMSEN ◽  
MADS J. SKYTTE ◽  
AMIRSALAR SAMKANI ◽  
ARNE ASTRUP ◽  
JAN FRYSTYK ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Weight Loss ◽  
Lipid Profile ◽  
Atherogenic Lipid Profile ◽  
Atherogenic Lipid

Pengaruh Teknik Distraksi Audio terhadap Penurunan Skala Nyeri pada Proses Pemasangan Intravena Fluid Drip

2019 ◽  
Vol 3 (2) ◽  
pp. 82-89
Author(s):  
Gamma Nurul Wardah ◽  
Sigit Purwanto ◽  
Karolin Adhisty
Keyword(s):  
P Value ◽  
Group Comparison ◽  
Probability Sampling ◽  
Purposive Sampling

Salah satu stressor utama yang terjadi pada anak saat hospitalisasi adalah nyeri yang juga dapat menimbulkan trauma. Tindakan pemasangan Intravena Fluid Drip (IVFD) yang dilakukan pada anak yang dihospitalisasi dapat menimbulkan nyeri akibat cedera jaringan tubuh (kulit). Teknik distraksi audio merupakan tindakan yang dirasa tepat untuk mengurangi nyeri yang ditimbulkan. Tujuan penelitian untuk mengetahui pengaruh teknik distraksi audio terhadap penurunan skala nyeri pemasangan IVFD pada anak prasekolah.Desain penelitian ini adalah pre experimental designwithstatic group comparison dengan menggunakan analisa data uji t tidak berpasangan. Sampel pada penelitian ini berjumlah 32 orang anak prasekolah yang dilakukan pemasangan IVFD dengan metode non probability sampling dengan teknik purposive sampling. Pengukuran skala nyeri menggunakan observasi Face, Leg, Activity, Cry, and Consolability Scale (FLACC Scale).Hasil penelitian didapatkan perbedaan nilai rata-rata skala nyeri antara kelompok intervensi dan kelompok kontrol dengan p value = 0,001 (p < α 0,05). Hasil penelitian ini menunjukkan bahwa terdapat pengaruh teknik distraksi audio terhadap penurunan skala nyeri saat pemasangan IVFD pada anak prasekolah di RSUD Dr. H. Ibnu Sutowo Baturaja. Perawat sebaiknya menerapkan pemberian teknik distraksi audio dalam standar operasional prosedur pemasangan IVFD sebagai salah satu terapi nonfarmakologi pada anak prasekolah yang akan dilakukan pemasangan IVFD.

scholarly journals Advanced Lipoprotein Analysis Shows Atherogenic Lipid Profile That Improves After Metreleptin in Patients with Lipodystrophy

2019 ◽  
Vol 3 (8) ◽  
pp. 1503-1517 ◽  
Author(s):  
Alexandra B Kinzer ◽  
Robert D Shamburek ◽  
Marissa Lightbourne ◽  
Ranganath Muniyappa ◽  
Rebecca J Brown
Keyword(s):  
Insulin Resistance ◽  
High Density Lipoprotein ◽  
Lipid Profile ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Profile ◽  
Cvd Risk ◽  
Lipoprotein Particles ◽  
Atherogenic Lipid Profile ◽  
Atherogenic Lipid

Abstract Context Patients with lipodystrophy have dyslipidemia and insulin resistance. Leptin treatment with metreleptin in lipodystrophy decreases insulin resistance and lowers triglycerides without changing high-density lipoprotein. Detailed measurement of lipoprotein particles with nuclear magnetic resonance (NMR) spectroscopy can offer insights into cardiovascular disease (CVD) risk and lipid metabolism beyond a standard lipid panel. We hypothesized that patients with lipodystrophy would have a more atherogenic lipid profile than controls at baseline, which would be ameliorated with metreleptin treatment. Objective To characterize the lipoprotein profile in patients with lipodystrophy compared with controls and to evaluate effects of metreleptin treatment. Design, Setting, Patients, and Intervention Patients with lipodystrophy (N = 17) were studied before and after metreleptin for 2 weeks and 6 months and compared with 51 insulin-sensitive sex-matched controls. Main Outcome Measures Lipoprotein profiles were measured by NMR with the LP4 deconvolution algorithm, which reports triglyceride-rich lipoprotein particles (TRLPs), high-density lipoprotein particles (HDLPs), and low-density lipoprotein particles (LDLPs). Results Patients with lipodystrophy had elevated large TRLPs and smaller HDLPs and LDLPs compared with controls. Five patients with lipodystrophy had chylomicrons, compared with zero controls. Metreleptin decreased the size and concentration of TRLPs, eliminated chylomicrons in all but one patient, decreased LDLPs, and increased LDLP size. Metreleptin treatment did not have major effects on HDLPs. Conclusions Patients with lipodystrophy had an atherogenic lipoprotein profile at baseline consistent with elevated CVD risk, which improved after metreleptin treatment. The presence of fasting chylomicrons in a subset of patients with lipodystrophy suggests saturation of chylomicron clearance by lipoprotein lipase.

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