scholarly journals Relationship between vitamin D levels and brucellosis: a case-control study from Sanandaj, Iran

2021 ◽  
Author(s):  
Behzad Mohsenpour ◽  
Amjad Ahmadi ◽  
Anvar Mohammadi Baneh ◽  
Ebrahim Ghaderi ◽  
Shahla Afrasiabian ◽  
...  
Keyword(s):  
Vitamin D ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
Control Study

Background and Objectives: Brucellosis is a zoonotic disease that is caused by the Brucella species. This disease is common in Iran and its incidence is increasing .This study measures serum vitamin D levels in patients with brucellosis and healthy people. Materials and Methods: This research was conducted as a case-control study at Tohid Hospital, Sanandaj, Iran. The calculated sample size included 90 patients in the case group and 90 patients in the control group. The measurement of vitamin D levels in the case and control groups were performed by ELISA. Results: The mean serum vitamin D level was 19.91 ng/ml in the case group and 22.87 ng/ml in the control group. (Serum vitamin D level <10 ng/mL is accepted as deficiency, 10-30 ng/mL as insufficiency, 30-100 ng/mL as sufficiency, and >100 ng/mL as toxicity). Conclusion: There was no significant difference between the two groups in terms of vitamin D deficiency (p-value=0.097).

scholarly journals Assessment of Serum Vitamin D Levels in Patients with Vitiligo in Jordan: A Case-Control Study

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Diala M. Alshiyab ◽  
Firas A. Al-qarqaz ◽  
Leen H. Heis ◽  
Jihan M. Muhaidat ◽  
Wlla S. Eddin ◽  
...  
Keyword(s):  
Vitamin D ◽  
Case Control Study ◽  
Skin Diseases ◽  
Serum Vitamin ◽  
Case Control ◽  
Vitamin D Receptors ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
Control Study

Background. Low vitamin D serum levels have been associated with many autoimmune disorders and several other skin diseases. Vitiligo is an autoimmune disease characterized by destruction of melanocytes by immune mechanisms. Melanocytes express vitamin D receptors, and their function can be affected by vitamin D status. Objectives. The main objective of this study is to compare vitamin D levels in patients with vitiligo vs normal population and whether vitamin D deficiency is associated with vitiligo. Methods. A case-control study was conducted. 100 vitiligo patients and 100 as controls were included in this study. Serum vitamin D level was measured for both vitiligo patients and controls, results were compared, and statistical analysis was done to compare the results. Results. The median age of vitiligo cases was 23 years (ranges, 2–80). 58% of vitiligo patients were females. The median vitamin D level was not significantly different between the two groups (vitiligo = 14.1 (IQR 9.9–20.4) vs control = 16.5 (IQR 10.3–25.3) (P=0.28)). Most vitiligo cases and controls were found to have low levels of vitamin D (either insufficient 20–30 ng/mL or low <20 ng/mL). Conclusions. There was no significant difference in vitamin D levels in vitiligo patients compared to controls. However, vitamin D levels were generally low in both groups.

scholarly journals Correlation of serum vitamin D levels and anemia in childhood pneumonia: a case control study from rural area

2017 ◽  
Vol 4 (3) ◽  
pp. 756
Author(s):  
Suhas P. Kulkarni ◽  
Ashok A. Chougule
Keyword(s):  
Vitamin D ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Case Control ◽  
Control Group ◽  
Immunomodulatory Activity ◽  
Healthy Children ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Control Study

Background: Pneumonia remains number one cause for morbidity and mortality in children. Vitamin D has been shown to have immunomodulatory activity. Hence to find correlation between vitamin D and pneumonia cases the study was carried out.Methods: A case control study was conducted at a rural hospital in Vadgaon. From September 2015 onwards all children under 5 years of age hospitalized with pneumonia were invited to participate in our study. Patients who consented for study underwent serum vitamin 25 (OH) D3 estimation along with other routine investigations as indicated. During the same study period, parents of otherwise healthy children fewer than 5 years age who came to our immunization clinic were invited to participate in the study as a control group.Results: Vitamin 25(OH) D3 levels in pneumonia cases study group (N=40) 12.048±6.015 ng/ml (Mean±SD) and in control (N=35) 22.65±11.77 ng/ml (mean±SD) that is statistically significant (P<0.0001) and hemoglobin (Hb) in Cases (N=40) with 8.55±1.27 gm/dl (mean±SD); control group (N=19) with 10.31±0.9 gm/dl (mean±SD)levels was found to be statistically significant (p < 0.0001).All patients with severe pneumonia needing ICU management were found to be deficient in vitamin D levels. Children with pneumonia had higher level of anemia. All children admitted to ICU had Moderate to severe anemia.Conclusions: There is a correlation between Vitamin D deficiency and severity of pneumonia and there is also correlation between level of anemia and severity of pneumonia.

scholarly journals A case control study of serum vitamin D levels in alopecia areata

2020 ◽  
Vol 8 (10) ◽  
pp. 3550
Author(s):  
Bobbili Tarun Kesava Naidu ◽  
Kavya Baddireddy
Keyword(s):  
Vitamin D ◽  
Alopecia Areata ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Autoimmune Disorder ◽  
Case Control ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Severity Of The Disease ◽  
Control Study

Background: Alopecia areata is an autoimmune disorder of anagen hair follicle leading to distressing and relapsing non-scarring hair loss. Vitamin D is an immunomodulator and plays a role in regulating normal hair cycle. Recent evidence suggests inconsistent association between vitamin D deficiency and alopecia areata.Methods: This case control study included 70 newly diagnosed cases of alopecia areata and 70 healthy controls. Competitive chemiluminescence immunoassay was used to determine and compare the serum vitamin D (25‑hydroxyvitamin D) levels between these groups. Also, the serum vitamin D levels correlation with severity of the disease was studied. ANOVA test and student t test were used for the statistical analysis.Results: Serum Vitamin D levels were significantly decreased in alopecia areata patients than in controls (p<0.05). There was no stastically significant relationship between serum 25-OH Vitamin D levels and severity of the disease (p=0.06).Conclusions: Prevalence of serum 25 (OH) deficiency was significantly higher in alopecia areata group. However no significant relation was found with disease severity.

scholarly journals The determinants of serum vitamin D levels in participants in a melanoma case–control study living in a temperate climate

2011 ◽  
Vol 22 (10) ◽  
pp. 1471-1482 ◽  
Author(s):  
John R. Davies ◽  
Yu-Mei Chang ◽  
Helen Snowden ◽  
May Chan ◽  
Susan Leake ◽  
...  
Keyword(s):  
Vitamin D ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Case Control ◽  
Temperate Climate ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Control Study ◽  
Melanoma Case

scholarly journals Serum vitamin D and immunoglobulin E levels in children of allergic rhinitis: a case-control study from Central India

2021 ◽  
Vol 8 (6) ◽  
pp. 1038
Author(s):  
Payasvi Baweja Sachdeva ◽  
Sheloj Joshi ◽  
Shweta Anand
Keyword(s):  
Vitamin D ◽  
Case Control Study ◽  
Immunoglobulin E ◽  
Serum Vitamin ◽  
Serum Ige ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
The Mean ◽  
Control Study

Background: Allergic rhinitis (AR) is the commonest type of non-infective rhinitis. Genetic and environmental factors play an important role in the development of the disease. Researchers are having interest in knowing the role of vitamin D in the pathogenesis of allergy. Immunoglobulin E (IgE) is integral to the pathogenesis of allergic disorders. However, the relationship between serum IgE levels and AR is still a matter of debate. Thus, this study aimed to know serum IgE and serum 25 (OH) vitamin D levels in patients with clinically diagnosed AR and control group.Methods: A case-control study was performed from May 2019 to October 2019 in LNMC and JK hospital. All 54 children with physician diagnosed AR aged 12 to 18 years of both genders who have come in the OPD (total enumeration sampling) during the above mentioned period were enrolled into the study and their 54 healthy counterparts are taken as controls. Other parameters such as age, gender, occupation and region of residence were also compared between the groups.Results: This study found highly significant difference in the mean serum IgE levels while there is a significant difference in the mean serum vitamin D levels between two groups.Conclusions: The study group with AR had significantly higher mean level of serum IgE and lower mean serum vitamin D levels as compared to control groups. However, upon stratification of vitamin D levels, the differences were insignificant. Further studies should be conducted to know the value of IgE as a prognostic factor of AR severity and to throw more light on association of vitamin D with AR.

scholarly journals Prediagnostic Serum Vitamin D Levels and the Risk of Crohn’s Disease and Ulcerative Colitis in European Populations: A Nested Case-Control Study

2018 ◽  
Vol 24 (3) ◽  
pp. 633-640 ◽  
Author(s):  
Jorrit L Opstelten ◽  
Simon S M Chan ◽  
Andrew R Hart ◽  
Fiona D M van Schaik ◽  
Peter D Siersema ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Vitamin D ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Case Control ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Nested Case Control ◽  
Control Study ◽  
European Populations
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