scholarly journals Evaluation of follicular fluid’s Beta-Human chorionic gonadotropin in the follicles of patient undergoing Intracytoplasmic sperm injection: A cross-sectional study

2019 ◽  
Vol 16 (12) ◽  
pp. 801
Author(s):  
Masoumeh Hajshafiha ◽  
Tahere Behrouzi lak ◽  
Nasrin Hajiloo ◽  
Yaghoub Deldar ◽  
Mina Ghorbani ◽  
...  
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Intracytoplasmic Sperm Injection ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Beta Human Chorionic Gonadotropin

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scholarly journals The Relationship Between Endometrial Thickness and Endometrial Pattern With Pregnancy Rate Based on Positive Serum Beta-Human Chorionic Gonadotropin

2019 ◽  
Vol 7 (3) ◽  
pp. 400-403
Author(s):  
Nasim Behnoud ◽  
Raheleh Rezaei ◽  
Elham Esform ◽  
Farahnaz Farzaneh
Keyword(s):  
Pregnancy Rate ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Endometrial Thickness ◽  
Cross Sectional Study ◽  
Transvaginal Sonography ◽  
Cross Sectional ◽  
Beta Human Chorionic Gonadotropin ◽  
Endometrial Pattern ◽  
Hcg Test

Objectives: Infertility is defined as the lack of pregnancy after one year of sexual contact without using any contraception. The aim of this study was to investigate the association between endometrial thickness (ET) and endometrial pattern with beta-human chorionic gonadotropin (B-HCG) test in women undergoing the induction of ovulation who referred to the infertility clinic of Ali ibn-e Abitalib hospital in Zahedan. Materials and Methods: This cross-sectional study was conducted at Ali ibn-e Abitaleb hospital in Zahedan (Iran) in 2017. The ET and endometrial pattern were estimated using transvaginal sonography and the pregnancy rate was determined based on B-HCG test. Finally, the data were analyzed by SPSS using the Chi-square test and independent t-test. Results: A total of 200 individuals with a mean age of 29.6 ± 5.6 years were evaluated in this study. The negative or positive B-HCG distribution was significantly different in terms of the endometrial pattern (P=0.001) so that 35.3% of women had B-HCG positive cases in the three-line pattern of ET while in the homogenous pattern, 3.3% had B-HCG positive cases. In addition, the pregnancy rate in women with ET greater than 7 mm was significantly higher compared to those women with ET less than 7 mm thickness (35.1% vs. 12.8%, P<0.001). Conclusions: Overall, the results of this study showed a significant correlation between the endometrial pattern and ET and pregnancy rate based on positive B-HCG test.

scholarly journals Male Inflammatory Parameters Are not Useful to Predict the Outcomes of Intracytoplasmic Sperm Injection: Results from a Cross-Sectional Study

2019 ◽  
Vol 37 (3) ◽  
pp. 347 ◽  
Author(s):  
Gianmartin Cito ◽  
Maria Elisabetta Coccia ◽  
Rita Picone ◽  
Andrea Cocci ◽  
Giorgio Ivan Russo ◽  
...  
Keyword(s):  
Intracytoplasmic Sperm Injection ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Inflammatory Parameters

scholarly journals Does Postevacuation β-Human Chorionic Gonadotropin Level Predict the Persistent Gestational Trophoblastic Neoplasia?

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Azam Sadat Mousavi ◽  
Samieh Karimi ◽  
Mitra Modarres Gilani ◽  
Setareh Akhavan ◽  
Elahe Rezayof
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Predictive Factor ◽  
Hydatidiform Mole ◽  
Area Under The Curve ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Molar Pregnancy ◽  
Gestational Trophoblastic Neoplasia ◽  
Cross Sectional

β-human chorionic gonadotropin (HCG) level is not a reliable marker for early identification of persistent gestational trophoblastic neoplasia (GTN) after evacuation of hydatidiform mole. Thus, this study was conducted to evaluate β-HCG regression after evacuation as a predictive factor of malignant GTN in complete molar pregnancy. Methods. In this cross-sectional study, we evaluated a total of 260 patients with complete molar pregnancy. Sixteen of the 260 patients were excluded. Serum levels of HCG were measured in all patients before treatment and after evacuation. HCG level was measured weekly until it reached a level lower than 5 mIU/mL. Results. The only predictors of persistent GTN are HCG levels one and two weeks after evacuation. The cut-off point for the preevacuation HCG level was 6000 mIU/mL (area under the curve, AUC, 0.58; sensitivity, 38.53%; specificity, 77.4%), whereas cut-off points for HCG levels one and two weeks after evacuation were 6288 mIU/mL (AUC, 0.63; sensitivity, 50.46%; specificity, 77.0%) and 801 mIU/mL (AUC, 0.80; sensitivity, 79.82%; specificity, 71.64%), respectively. Conclusion. The rate of decrease of HCG level at two weeks after surgical evacuation is the most reliable and strongest predictive factor for the progression of molar pregnancies to persistent GTN.

scholarly journals Evaluating the agreement of ultrasound imaging and beta-human chorionic gonadotropin (β-hCG) measurement in confirming completed medical abortion: cross-sectional study

2021 ◽  
Vol 2021 (2) ◽  
Author(s):  
Mahboubeh Peracheh ◽  
Batool Teymouri ◽  
Narjes Noori ◽  
Taraneh Arbabzadeh ◽  
Marzieh Ghasemi
Keyword(s):  
Ultrasound Imaging ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Transvaginal Ultrasound ◽  
Medical Abortion ◽  
First Trimester ◽  
Cross Sectional ◽  
Predictive Values ◽  
Beta Human Chorionic Gonadotropin ◽  
Β Hcg

Objective: Clinical methods that are generally used to evaluate the completeness of medical abortion are not reliable. Ultrasound imaging and beta-human chorionic gonadotropin (β-hCG) measurements are used to diagnose completed medical abortion, but a precise evaluation of these two methods has shown contradictory results. The purpose of this study is to evaluate the agreement of serum β-hCG measurement and ultrasound imaging to confirm complete medical abortion. Materials and Methods: This study was conducted on pregnant women who had been referred to our center for medical abortion from 2015 to 2017. All cases occurred in the first trimester of pregnancy. They obtained one or two doses of vaginal misoprostol for medical abortion. Success rate of medical abortion was measured by both transvaginal ultrasound imaging and consecutive serum β-hCG measurements two to four weeks after initial treatment. Results: Among the 275 women who completed the study, complete medical abortion was confirmed by serum β-hCG in 231 women (84.3%) and transvaginal ultrasound imaging in 195 women (70.8%) after two weeks. All remaining cases completed the medical abortion after an additional two weeks, confirmed by both transvaginal ultrasound imaging and serum β-hCG. The sensitivity, specificity, positive, and negative predictive values of β-hCG were 95.2%, 86.7%, 84%, and 70%, respectively; and these values for transvaginal ultrasound imaging were 68.5% 64.5%,77%, and 30.%, respectively, for the diagnosis of completed medical abortion. Conclusion: Serum β-hCG measurement is as effective as transvaginal ultrasound imaging to confirm successful medical abortion in early pregnancy.

scholarly journals Comparison of intracytoplasmic sperm injection outcomes in azoospermic men who underwent testicular sperm extraction vs. microdissection testicular sperm extraction: A cross-sectional study

2021 ◽  
pp. 837-844
Author(s):  
Serajoddin Vahidi ◽  
Nima Narimani ◽  
Saeid Abouei ◽  
Ali Sadeghi ◽  
Keivan Lorian ◽  
...  
Keyword(s):  
Live Birth ◽  
Intracytoplasmic Sperm Injection ◽  
Birth Rate ◽  
Live Birth Rate ◽  
Cross Sectional Study ◽  
Testicular Sperm Extraction ◽  
Sectional Study ◽  
Testicular Sperm ◽  
Cross Sectional ◽  
Biochemical Pregnancy

Background: Outcomes of intracytoplasmic sperm injection (ICSI) may be different in azoospermic men who undergo testicular sperm extraction (TESE) vs. microdissection-TESE (micro-TESE). Objective: This study was conducted to compare the ICSI outcomes in men who underwent TESE vs. micro-TESE due to obstructive azoospermia and nonobstructive azoospermia, respectively. Materials and Methods: A total of 310 azoospermic men who underwent ICSI from September 2016 to September 2020 were enrolled in this cross-sectional study and divided into two groups (172 cases in the TESE and 138 cases in the micro-TESE group). The paternal and maternal age, and the fertilization, biochemical pregnancy, abortion and live birth rates were compared between the two groups. Results: Maternal mean age was significantly higher in the TESE group (34.9 ± 4.2 yr vs. 32.3 ± 5.7 yr). The fertilization and biochemical pregnancy rates were significantly higher in the TESE group, but the abortion rate was similar in the two groups. The live birth rate was higher in the TESE group, but this difference was not significant (p = 0.06). Also, the maternal and paternal age did not affect ICSI outcomes. Conclusion: Individuals who underwent TESE had higher fertilization and biochemical pregnancy rates than those who underwent micro-TESE, but the live birth rate was not significantly different. Keywords: Intracytoplasmic sperm injection, Azoospermia, Testicular sperm extraction, Microdissection testicular sperm extraction, Pregnancy outcome.

scholarly journals The effect of seasonality on reproductive outcome of patients undergoing intracytoplasmic sperm injection: A descriptive cross-sectional study

2020 ◽  
Author(s):  
Marzieh Mehrafza ◽  
Maryam Asgharnia ◽  
Azadeh Raoufi ◽  
Elmira Hosseinzadeh ◽  
Sajedeh Samadnia ◽  
...  
Keyword(s):  
Assisted Reproductive Technology ◽  
Pregnancy Outcome ◽  
Intracytoplasmic Sperm Injection ◽  
Cross Sectional Study ◽  
Reproductive Technology ◽  
Seasonal Effect ◽  
Medical Institute ◽  
Sectional Study ◽  
Cross Sectional ◽  
Injection Cycle

Background: There is conflicting evidence regarding the impact of season on the assisted reproductive technology outcome. Objective: To retrospectively compare three year outcome of women undergoing their first intracytoplasmic sperm injection cycle, across seasons. Materials and Methods: In this descriptive cross-sectional study, 3,670 women who underwent their first intracytoplasmic sperm injection cycle in Mehr Medical Institute, Rasht, Iran between April 2010 and May 2014 were studied. Women were divided into four groups according to the day of oocyte retrival as: spring (n = 808), summer (n = 994), autumn (n = 1066), and winter (n = 802). Basal and stimulation charecteristics were compared among groups. Results: While sperm concentration and motility were significantly lower during summer, the total number of retrieved and metaphase II oocytes were significantly higher (p = 0.0001, p = 0.0001, p = 0.004, p = 0.02, respectively). Fertilization rate were significantly higher during autumn (p = 0.0001). Also, the number of high- quality transferred embryos were significantly higher during summer and winter (p = 0.03). A similar pattern was observed in implantation rate and pregnancy over the four seasons Conclusion: Despite the fact that intracytoplasmic sperm injection minimize the seasonal effect on pregnancy outcome, changes in pregnancy rate still occur among different seasons without particular pattern. It seems that performing assisted reproductive technology procedures in a particular season should be considered as an effective factor. Key words: Intracytoplasmic sperm injection, Seasons, Pregnancy outcome.

scholarly journals Is there any correlation between Estradiol supplementation, as luteal phase support, and clinical pregnancy in ART cycles? A cross-sectional study

2020 ◽  
Author(s):  
Maryam Eftekhar ◽  
Banafsheh Mohammadi ◽  
Esmat Mangoli ◽  
Maryam Mortazavi
Keyword(s):  
Pregnancy Rate ◽  
Embryo Transfer ◽  
Intracytoplasmic Sperm Injection ◽  
Luteal Phase ◽  
Cross Sectional Study ◽  
Clinical Pregnancy ◽  
Control Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Luteal Phase Support

Background: Endometrial receptivity is one of the important factors in assisted reproductive technology (ART) success. In the luteal phase of an ART cycle, serum estradiol (E2) and progesterone are often placed in low levels. Supporting the luteal phase with progesterone is a usual method. Objective: To evaluate the effects of E2 supplementation plus progesterone on the luteal phase support in the antagonist protocol who have undergone intracytoplasmic sperm injection-embryo transfer cycles. Materials and Methods: In this cross-sectional study, 200 patients with antagonist stimulation protocol, who had undergone intracytoplasmic sperm injection treatment, were divided into two groups based on the use of E2 supplementation. In both groups, 400 mg progesterone suppositories (Cyclogest®), twice a day/vaginally, was administered starting from the day of oocyte collection until the fetal heart activity. However, in the E2 group, in addition to progesterone, 4 mg tablet of E2 was received daily. Beta hCG was checked 14 days after the embryo transfer, and the clinical pregnancy rate was the main endpoint. Results: The patients’ characteristics were matched, and insignificant differences were observed, except for endometrial thickness. The clinical outcomes showed the rate of pregnancy was higher in the E2 group compared to the control group; nonetheless, statistically, there was no noticeable difference. Conclusion: E2 supplementation had no beneficial effect in the luteal phase support of IVF cycles. Nevertheless, more studies are required to confirm the supportive role of E2 supplementation for embryo implantation and to improve the outcomes in ART cycles. Key words: Luteal phase, Estradiol, Progesterone, ICSI, Pregnancy rate.

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