scholarly journals Ultrasound-guided FNA Efficiency in Diagnosing of Metastatic Nodes of Oral Squamous Cell Carcinoma; Article Review

2021 ◽  
Author(s):  
Sona Rafieyan ◽  
Yousef Kananizadeh ◽  
Elahe Reyhani
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Critical Issue ◽  
Lymph Node Status ◽  
Depth Of Invasion ◽  
Nodal Disease ◽  
Oral Neoplasms ◽  
Pattern Differentiation

Oral cancer comprises a group of neoplasms affecting any fields of the oral cavity, pharyngeal regions and salivary glands. However, this term tends to be used interchangeably with oral squamous cell carcinoma (OSCC), which represents the most common of all oral neoplasms. It is estimated that more than 90% of all oral neoplasms are OSCC. Oral SCC prefers to spread through the lymphatic system than the bloodstream, and in this region tongue tumors have the greatest potential for neck metastases.Primary tumor’s histopathologic features like depth of invasion, thickness, growth pattern, differentiation, lymphovascular or vascular invasion have a limited prognostic value for nodal disease. cervical lymph node status accurate assessment in HNSCC patients is critical issue because of its influences on prognosis and treatment decisions, USgFNAC proved widely accepted not only because of safety and availability in diagnosis but also it is repeatable, minimally invasive and cost-effectiveness.

Tumor depth of invasion and prognosis of early‐stage oral squamous cell carcinoma: A meta‐analysis

Oral Diseases ◽  
2019 ◽  
Vol 26 (7) ◽  
pp. 1357-1365 ◽  
Author(s):  
Patrícia Carlos Caldeira ◽  
Andrea María López Soto ◽  
Maria Cássia Ferreira Aguiar ◽  
Carolina Castro Martins
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Meta Analysis ◽  
Depth Of Invasion ◽  
Tumor Depth

scholarly journals Intraoral Ultrasound in the Evaluation of Depth of Invasion in OSCC. Preliminary Results

Proceedings ◽  
2019 ◽  
Vol 35 (1) ◽  
pp. 28
Author(s):  
Graniero ◽  
D’Alessandro ◽  
Montori ◽  
Rocchetti ◽  
Cantisani ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Surgical Treatment ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lymphatic Spread ◽  
Depth Of Invasion ◽  
Preliminary Results

Oral Squamous Cell Carcinoma (OSCC) shows an early tendency to lymphatic spread rather than hematogenous. The surgical treatment cannot be considered oncologically complete if the neck is not evaluated [1]. [...]

scholarly journals The Outline of Prognosis and New Advances in Diagnosis of Oral Squamous Cell Carcinoma (OSCC): Review of the Literature

2013 ◽  
Vol 2013 ◽  
pp. 1-13 ◽  
Author(s):  
Esam Ahmad Omar
Keyword(s):  
Squamous Cell Carcinoma ◽  
Prognostic Factors ◽  
Oral Cancer ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Imaging Techniques ◽  
Publication Date ◽  
Depth Of Invasion ◽  
Tumour Thickness

Objective. Oral squamous cell carcinoma (OSCC) has a remarkable incidence over the world and a fairly strenuous prognosis, encouraging further research on the prognostic factors and new techniques for diagnosis that might modify disease outcome. Data Sources. A web-based search for all types of articles published was initiated using Medline/Pub Med, with the key words such as oral cancer, prognostic factors of oral cancer, diagnostic method of oral cancer, and imaging techniques for diagnosis of oral cancer. The search was restricted to articles published in English, with no publication date restriction (last update April, 2013). Review Methods. In this paper, I approach the factors of prognosis of OSCC and the new advances in diagnostic technologies as well. I also reviewed available studies of the tissue fluorescence spectroscopy and other noninvasive diagnostic aids for OSCC. Results. The outcome is greatly influenced by the stage of the disease (especially TNM). Prognosis also depends or varies with tumour primary site, nodal involvement, tumour thickness, and the status of the surgical margins. Conclusion. Tumour diameter is not the most accurate when compared to tumour thickness or depth of invasion, which can be related directly to prognosis. There is a wide agreement on using ultrasound guided fine needle aspiration biopsies in the evaluation of lymph node metastasis.

scholarly journals Evidences Suggesting Involvement of Viruses in Oral Squamous Cell Carcinoma

2013 ◽  
Vol 2013 ◽  
pp. 1-17 ◽  
Author(s):  
Kanupriya Gupta ◽  
Rashmi Metgud
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Oncogenic Viruses ◽  
Major Health Problem ◽  
Oral Neoplasms ◽  
Potential Factors

Oral cancer is one of the most common cancers and it constitutes a major health problem particularly in developing countries. Oral squamous cell carcinoma (OSCC) represents the most frequent of all oral neoplasms. Several risk factors have been well characterized to be associated with OSCC with substantial evidences. The etiology of OSCC is complex and involves many factors. The most clearly defined potential factors are smoking and alcohol, which substantially increase the risk of OSCC. However, despite this clear association, a substantial proportion of patients develop OSCC without exposure to them, emphasizing the role of other risk factors such as genetic susceptibility and oncogenic viruses. Some viruses are strongly associated with OSCC while the association of others is less frequent and may depend on cofactors for their carcinogenic effects. Therefore, the exact role of viruses must be evaluated with care in order to improve the diagnosis and treatment of OSCC. Although a viral association within a subset of OSCC has been shown, the molecular and histopathological characteristics of these tumors have yet to be clearly defined.

Clinicopathological and Prognostic Significance of p27 Expression in Oral Squamous Cell Carcinoma: A Meta-Analysis

2013 ◽  
Vol 28 (4) ◽  
pp. 329-335 ◽  
Author(s):  
Ling Gao ◽  
Wanjie Gu ◽  
Jingjing Zheng ◽  
Wenhao Ren ◽  
Su'e Chang ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Publication Bias ◽  
Squamous Cell ◽  
Meta Analysis ◽  
Clinicopathological Parameters ◽  
Lymph Node Status

Despite being already known that p27 can regulate cell proliferation, cell motility and apoptosis, the role of p27 expression in oral squamous cell carcinoma (OSCC) remains controversial. The purpose of this study was to comprehensively evaluate, with a meta-analysis, the clinicopathological and prognostic role of p27 expression in OSCC. A meta-analysis of eligible studies was performed to assess the effects of p27 expression on clinicopathological parameters and overall survival (OS) in patients with OSCC, using pooled relative risks with 95% confidence intervals. Heterogeneity and publication bias were also assessed. Fourteen studies involving a total of 1,010 patients met the inclusion criteria. Low p27 expression was significantly associated with advanced TNM stage (p<0.001), worse histology (p=0.025), and lymph node metastasis (p<0.001), but not with tumor size (p=0.181). The pooled RR of 0.743 (p=0.002) suggested that low p27 expression has a poor prognosis in patients with OSCC. A significant heterogeneity among studies was detected for lymph node status (χ2=34.60, I2=68.2%, p<0.001) and OS (χ2=14.86, I2=39.4%, p=0.095). We did not detect a significant publication bias in this meta-analysis. Our meta-analysis suggests that p27 expression status might be useful as a predictive biomarker in clinical practice, and might potently predict OS in OSCC patients.

Sign in / Sign up

Export Citation Format

Share Document