Associations between Dietary Acid Load and Migraine Headache Severity and Duration among Women: A Cross-Sectional Study

Background: Migraine is a recurrent disorder which can cause socio-economic and public health burdens. Many factors, especially dietary factors are suggested to induce migraine headaches. The aim of this study was to examine the association between plant-based dietary patterns and headache severity and duration among migraine patients. Methods: A sample of two hundred and sixty-six women with migraine (18-50 years) took part in the present cross-sectional study. Dietary intake data was collected using a validated and reliable food-frequency questionnaire. Three dietary indices were evaluated including an overall plant-based diet (PDI), healthful Plant-based diet (hPDI), and unhealthful plant-based diet (uPDI). Anthropometric measurements, headache duration, Migraine Disability Assessment (MIDAS), and Visual Analog Scale (VAS) were assessed for all cases. Multinomial logistic regression and linear regression models were used to show the association between headaches and plant-based dietary patterns. Results: An inverse association between higher adherence to hPDI and severity of headaches was found based on VAS (OR=0.40; 95% CI: 0.21, 0.74; p=0.003), and severe disability based on MIDAS (OR=0.50; 95% CI: 0.26, 0.95; p=0.03). Conversely, uPDI scores were positively associated with severe headaches (OR=3.00; 95% CI: 1.72, 5.23; p<0.001), and disability (OR=2.50; 95% CI: 1.39, 4.51; p=0.001). Moreover, headaches duration showed an inverse significant association with hPDI scores (β=-0.21, 95% CI=-4.69, -1.08, p=0.002). Conclusion: Plant-based diet, particularly healthful plant foods, was inversely associated with lower severity, disability and duration of headaches. In addition, unhealthy plant foods were associated with higher risk of migraine headaches.

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Association of dietary acid load with cardiovascular risk factors and the prevalence of metabolic syndrome in Iranian women: A cross-sectional study

Nutrition ◽

10.1016/j.nut.2019.110570 ◽

2019 ◽

Vol 67-68 ◽

pp. 110570 ◽

Cited By ~ 3

Author(s):

Hadis Mozaffari ◽

Nazli Namazi ◽

Bagher Larijani ◽

Nick Bellissimo ◽

Leila Azadbakht

Keyword(s):

Risk Factors ◽

Metabolic Syndrome ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors ◽

Cross Sectional Study ◽

Sectional Study ◽

Iranian Women ◽

Cross Sectional ◽

Dietary Acid ◽

Acid Load

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Lower vegetable protein intake and higher dietary acid load associated with lower carbohydrate intake are risk factors for metabolic syndrome in patients with type 2 diabetes: Post‐hoc analysis of a cross‐sectional study

Journal of Diabetes Investigation ◽

10.1111/jdi.12326 ◽

2015 ◽

Vol 6 (4) ◽

pp. 465-472 ◽

Cited By ~ 18

Author(s):

Hiroya Iwase ◽

Muhei Tanaka ◽

Yukiko Kobayashi ◽

Sayori Wada ◽

Masashi Kuwahata ◽

...

Keyword(s):

Protein Intake ◽

Vegetable Protein ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Post Hoc Analysis ◽

Dietary Acid ◽

Acid Load ◽

Post Hoc

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The Association of Dietary Acid Load with Resting Metabolic Rate and Metabolic Components in Overweight and Obese Women: A Cross Sectional Study

10.21203/rs.3.rs-141018/v1 ◽

2021 ◽

Author(s):

Atieh Mirzababaei ◽

Farideh Shiraseb ◽

Leila Setayesh ◽

Atefeh Tavakoli ◽

Cain C. T. Clark ◽

...

Keyword(s):

Metabolic Rate ◽

Resting Metabolic Rate ◽

Cross Sectional Study ◽

The Body ◽

Adult Women ◽

Sectional Study ◽

Cross Sectional ◽

Dietary Acid Load ◽

Dietary Acid ◽

Acid Load

Abstract Background: Several epidemiologic studies have reported that dietary acid load is associated with metabolic profiles; however, to our knowledge, the relationship of this dietary pattern with resting metabolic rate (RMR) among obese and overweight females remains unreported. Therefore, this study aimed to evaluate the association of dietary acid load RMR and metabolic components among overweight and obese adult women.Methods: This cross-sectional study was conducted on 375 Iranian adults, aged 18–48 years. Dietary acid load indexes were calculated by using a validated 147-item semi-quantitative FFQ. Biochemical and anthropometric measures were assessed using standard methods. An impedance fat analyzer was used to obtain the body composition and an indirect calorimeter was used to assess the RMR. Result: It was observed that after correction for potential confounders, DBP and NEAP and PRAL scores were inversely associated (P<0.05). NEAP index was inversely associated with RMR (β= -0.25, 95% CI=-0.1.5 to 2.08, P=0.02), and positively associated with WC (β= 1.009, 95% CI=-1.43 to 3.45, P=0.05) and WHR (β= 0.01, 95% CI= -0.01 to0.04, P=0.03), such that subjects with higher scores in NEAP had lower RMR and higher WC and WHR. We also observed that DAL (β= -0.02, 95% CI= -0.08 to0.03, P=0.08) and PRAL (β= -0.037, 95% CI= -1.05 to 0.03 P=0.07) were marginally associated with RMR.Conclusion:The results of the present study suggested that higher dietary acid load scores may be negatively associated with lower RMR, while directly associated with greater WC, WHR, DBP, and HOMA-IR.

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The Association of Dietary Acid Load with Resting Metabolic Rate and Metabolic Components in Overweight and Obese Women: A Cross Sectional Study

10.21203/rs.3.rs-141018/v2 ◽

2021 ◽

Author(s):

Atieh Mirzababaei ◽

Farideh Shiraseb ◽

Leila Setayesh ◽

Atefeh Tavakoli ◽

Cain C. T. Clark Clark ◽

...

Keyword(s):

Metabolic Rate ◽

Resting Metabolic Rate ◽

Cross Sectional Study ◽

The Body ◽

Adult Women ◽

Sectional Study ◽

Cross Sectional ◽

Dietary Acid Load ◽

Dietary Acid ◽

Acid Load

Abstract Background: Several epidemiologic studies have reported that dietary acid load is associated with metabolic profiles; however, to our knowledge, the relationship of this dietary pattern with resting metabolic rate (RMR) among obese and overweight females remains unreported. Therefore, this study aimed to evaluate the association of dietary acid load RMR and metabolic components among overweight and obese adult women.Methods: This cross-sectional study was conducted on 375 Iranian adults, aged 18–48 years. Dietary acid load indexes were calculated by using a validated 147-item semi-quantitative FFQ. Biochemical and anthropometric measures were assessed using standard methods. An impedance fat analyzer was used to obtain the body composition and an indirect calorimeter was used to assess the RMR. Result: It was observed that after correction for potential confounders, DBP and NEAP and PRAL scores were inversely associated (P<0.05). NEAP index was inversely associated with RMR (β= -0.25, 95% CI=-0.1.5 to 2.08, P=0.02), and positively associated with WC (β= 1.009, 95% CI=-1.43 to 3.45, P=0.05) and WHR (β= 0.01, 95% CI= -0.01 to0.04, P=0.03), such that subjects with higher scores in NEAP had lower RMR and higher WC and WHR. We also observed that DAL (β= -0.02, 95% CI= -0.08 to0.03, P=0.08) and PRAL (β= -0.037, 95% CI= -1.05 to 0.03 P=0.07) were marginally associated with RMR.Conclusion:The results of the present study suggested that higher dietary acid load scores may be negatively associated with lower RMR, while directly associated with greater WC, WHR, DBP, and HOMA-IR.

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The Association of Dietary Acid Load with Resting Metabolic Rate and Metabolic Components in Overweight and Obese Women: A Cross Sectional Study

Clinical Nutrition ESPEN ◽

10.1016/j.clnesp.2021.11.033 ◽

2021 ◽

Author(s):

Atieh Mirzababaei ◽

Farideh Shiraseb ◽

Leila Setayesh ◽

Atefeh Tavakoli ◽

Elnaz Daneshzad ◽

...

Keyword(s):

Metabolic Rate ◽

Resting Metabolic Rate ◽

Cross Sectional Study ◽

Obese Women ◽

Sectional Study ◽

Cross Sectional ◽

Dietary Acid Load ◽

Dietary Acid ◽

Acid Load

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The Association of Dietary Acid Load with Resting Metabolic Rate and Metabolic Components in Overweight and Obese Women: A Cross Sectional Study

10.21203/rs.3.rs-145354/v1 ◽

2021 ◽

Author(s):

Atieh Mirzababaei ◽

Farideh Shiraseb ◽

Leila Setayesh ◽

Atefeh Tavakoli ◽

Cain C. T. Clark Clark ◽

...

Keyword(s):

Metabolic Rate ◽

Resting Metabolic Rate ◽

Cross Sectional Study ◽

The Body ◽

Adult Women ◽

Sectional Study ◽

Cross Sectional ◽

Dietary Acid Load ◽

Dietary Acid ◽

Acid Load

Abstract Background: Several epidemiologic studies have reported that dietary acid load is associated with metabolic profiles; however, to our knowledge, the relationship of this dietary pattern with resting metabolic rate (RMR) among obese and overweight females remains unreported. Therefore, this study aimed to evaluate the association of dietary acid load RMR and metabolic components among overweight and obese adult women.Methods: This cross-sectional study was conducted on 375 Iranian adults, aged 18–48 years. Dietary acid load indexes were calculated by using a validated 147-item semi-quantitative FFQ. Biochemical and anthropometric measures were assessed using standard methods. An impedance fat analyzer was used to obtain the body composition and an indirect calorimeter was used to assess the RMR. Result: It was observed that after correction for potential confounders, DBP and NEAP and PRAL scores were inversely associated (P<0.05). NEAP index was inversely associated with RMR (β= -0.25, 95% CI=-0.1.5 to 2.08, P=0.02), and positively associated with WC (β= 1.009, 95% CI=-1.43 to 3.45, P=0.05) and WHR (β= 0.01, 95% CI= -0.01 to0.04, P=0.03), such that subjects with higher scores in NEAP had lower RMR and higher WC and WHR. We also observed that DAL (β= -0.02, 95% CI= -0.08 to0.03, P=0.08) and PRAL (β= -0.037, 95% CI= -1.05 to 0.03 P=0.07) were marginally associated with RMR.Conclusion:The results of the present study suggested that higher dietary acid load scores may be negatively associated with lower RMR, while directly associated with greater WC, WHR, DBP, and HOMA-IR.

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High dietary acid load score is not associated with the risk of metabolic syndrome in Iranian adults

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000626 ◽

2020 ◽

pp. 1-12

Author(s):

Noushin Mohammadifard ◽

Golgis Karimi ◽

Alireza Khosravi ◽

Nizal Sarrafzadegan ◽

Mahnaz Jozan ◽

...

Keyword(s):

Metabolic Syndrome ◽

Blood Sugar ◽

Cross Sectional Study ◽

Dietary Intakes ◽

Cross Sectional ◽

Dietary Acid Load ◽

Net Endogenous Acid Production ◽

Increased Risk ◽

Dietary Acid ◽

Acid Load

Abstract. Background and objective: The association between dietary acid load and metabolic syndrome (MetS) risk is not well-known. Therefore, we aimed to investigate the relationship between dietary acid load and the risk of MetS among Iranian adults. Methods: This cross-sectional study was carried out on 1430 Iranian adults. Dietary intakes were assessed using a validated food frequency questionnaire. Dietary acid load was estimated using potential renal acid load (PRAL) and net endogenous acid production (NEAP). MetS was defined according to the ATP-III criteria. The risk of MetS and its components was explored using logistic regression test. Results: Totally, 205 individuals were identified to have MetS. No significant association for MetS was found across the quartiles of PRAL and NEAP either in the crude model [Q4 PRAL: OR (95% CI): 0.94 (0.67–1.32), and NEAP: OR (95% CI): 0.88 (0.63–1.25)] or fully-adjusted model [Q4 PRAL: OR (95% CI): 0.90 (0.61–1.33), and NEAP: OR (95% CI): 1.05 (0.70–1.57)]. Amongst the components of MetS, higher scores of NEAP was associated with an increased risk of impaired blood sugar after adjustment for potential confounders [OR (95% CI): 1.35 (0.93–1.96)]. No significant association was found for other components either with PRAL or with NEAP. Conclusion: Our findings suggest no association between dietary acid load and MetS risk in Iranian adults. However, higher dietary acid load, measured by NEAP, but not PRAL, was associated with increased risk of impaired fasting blood sugar. Longitudinal studies are warranted to explore whether a diet low in potential acid load could reduce MetS risk.

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