scholarly journals Clinical Profile of Acute Encephalitis Syndrome in Children with Special Reference to Japanese Encephalitis in a Tertiary Care Teaching Hospital of Upper Assam

2016 ◽  
Vol 04 (10) ◽  
pp. 13171-13178
Author(s):  
Pankaj P Panyang ◽  
2014 ◽  
Vol 9 (2) ◽  
pp. 31-37
Author(s):  
Lekhjung J Thapa ◽  
RS Twayana ◽  
R Shilpakar ◽  
MR Ghimire ◽  
A Shrestha ◽  
...  

Objective: Acute encephalitis syndrome is a cause of significant morbidity and mortality in Nepal. Although Japanese encephalitis virus (JEV) was thought to be a major cause for acute encephalitis syndrome, more non-Japanese encephalitis virus cases are reported. The outcome of patients with acute encephalitis syndrome is variable. Our study was designed to study the clinical profile and outcome of patients with acute encephalitis syndrome managed in tertiary care center in central Nepal. Methods: The record of patients admitted with diagnosis of acute encephalitis syndrome,from January 2010 to December 2010 in College of Medical Sciences-Teaching Hospital (CMS-TH) was reviewed. They were classified clinically as meningitis, encephalitis and meningoencephalitis. The clinical details and reports of the patients were recorded and analyzed. Results: Total of 85 cases of meningitis and encephalitis were identified. Mean age was 19.18 years. Fifty-six (65.9%) patients were males and 29 (34.1%) were females. Sixty (70.58%) patients had meningitis, 8 (9.41%) had encephalitis, and 17 (20.0%) had meningoencephalitis. JE serology was positive in 4 patients (4.7%). Seventy-two (84.7%) patients made full recovery and were discharged from hospital. Thirteen (15.3%) patients left against medical advice (LAMA). Conclusion: Acute encephalitis syndrome is still a major public health problem in Nepal. Few of these patients have Japanese Encephalitis. There is a trend towards improved outcome because of availability of improved health services. However, financial constraint remains a challenge in management of acute encephalitis syndrome. Journal of College of Medical Sciences-Nepal, 2013, Vol-9, No-2, 31-37 DOI: http://dx.doi.org/10.3126/jcmsn.v9i2.9685


Author(s):  
Sanjay Kumar Paliwal ◽  
Syed Javed ◽  
Arth Shah

Background: Snakebite - a global public health problem can be a traumatic experience for patients. They may develop local pain and swelling at the site with or without systemic involvement (haematological and neurological) and at times complications depending upon nature of snake. The present study was planned to determine the epidemiological and clinical profile of snakebite patients at a tertiary care teaching hospital of southern Rajasthan, India.Methods: This retrospective observational study was carried out at a tertiary care teaching hospital only after approval from institutional ethics committee. The data of patients aged between 18-80 years of either gender that had presented with a history of snakebite and admitted to the intensive care unit (ICU) in past 3 years were included. Data related to epidemiological, clinical and investigational parameters was collected and analysed. Data was presented as number (percentage) or mean ± standard deviation.Results: Total 80 patients were analyzed. Male:female ratio was 1.67:1 and mean age of study population was 33.91±14.34 years. Maximum 71 (89%) patients belonged to rural region. Only 16 (20%) patients complained of local pain. Bleeding was noted in 5 (6.25%) patients whereas 36 (45%) patients had ptosis. Prolonged coagulation markers were reported in 35 (44%) patients. Only 2 (2.5%) patients had acute kidney injury. Altered liver and renal function tests were noted in 71 (89%) and 63 (79%) patients respectively. Mechanical ventilation was required in 27 (34%) patients.Conclusions: Young adult males and rural population were prone to snakebites. Local and systemic manifestations were noted in relatively lesser patients compared to the published data. Only fewer patients in I.C.U. required mechanical ventilation.


2019 ◽  
Vol 9 (1) ◽  
pp. 45-49
Author(s):  
Sanjay Thorat ◽  
◽  
Tejas Rane ◽  
Akshay Kulkarni ◽  
Aniket Avhad ◽  
...  

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