Clinical Profile, Aetiology, and Short Term Outcome of Convulsive Status Epilepticus in Children in Eastern India

Background: Convulsive status epilepticus is the most common childhood medical neurological emergency, and is associated with significant morbidity and mortality. Most data for this disorder are from mainly adult populations and might not be relevant to childhood. This study was done to obtain a uniquely paediatric perspective. The objective of the study was to the etiology and short term outcome of patients admitted with status epilepticus between the age group 1 month to 12 years at a medical college hospital.Methods: Study design: Prospective descriptive study. Study Place: Department of Paediatrics, SIMS and RC, Bangalore, India. Study population: All children in the age group of 1 month to 12 years admitted with status epilepticus. Sample size:66. Study period: From January 2016 to December 2016.Results: Prevalence of status epilepticus among children admitted in this study was 8.7%. Most common age was found to be 1-3 years (54.5%). Preponderance of male (51.5%) over female (48.5%) was observed. The two most common etiology observed was Atypical febrile seizures (33.3%) and meningitis (22.7%). 57.5% children presented as first episode of seizure and duration of seizure was less than 2 hours in 65.1%.In our study, short term mortality rate was found to be 3% and morbidity was found to be 9% and meningitis was responsible for all the deaths. The mortality and morbidity in the form of neurodeficits were observed between the age group of 1 month to 3 years. Based on the duration of seizure lasting more than 8 hours, two third had mortality and one third had morbidity.Conclusions: Status epilepticus is a severe life threatening emergency with substantial morbidity and mortality. Major causes were due to atypical febrile seizure and meningitis. Patients with younger age, male sex and seizures lasting longer duration had higher mortality and morbidity, predicting the poor outcome.

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Clinical Profile and Short Term Outcome of Children with Neutropenia

The Indian Journal of Pediatrics ◽

10.1007/s12098-019-03020-4 ◽

2019 ◽

Vol 86 (11) ◽

pp. 1017-1020 ◽

Cited By ~ 1

Author(s):

Akanksha Mahajan ◽

Virendra Kumar ◽

Sangeeta Pahuja Sindhwani ◽

Viswas Chhapola

Keyword(s):

Clinical Profile ◽

Short Term ◽

Term Outcome ◽

Short Term Outcome

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Short term outcome for colorectal cancer patients undergoing surgery in Tertiary care center in Eastern India

European Journal of Surgical Oncology ◽

10.1016/j.ejso.2020.11.277 ◽

2021 ◽

Vol 47 (2) ◽

pp. e50-e51

Author(s):

Abhitesh Singh ◽

Anshul Jain ◽

Dillip Muduly ◽

Mahesh Sultania ◽

Jyoti Ranjan Swain ◽

...

Keyword(s):

Colorectal Cancer ◽

Cancer Patients ◽

Care Center ◽

Tertiary Care ◽

Tertiary Care Center ◽

Eastern India ◽

Short Term ◽

Term Outcome ◽

Short Term Outcome ◽

Colorectal Cancer Patients

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Clinical Profile and Short-Term Outcome of Children With SARS-CoV-2 Related Multisystem Inflammatory Syndrome (MIS-C) Treated With Pulse Methylprednisolone

Indian Pediatrics ◽

10.1007/s13312-021-2277-4 ◽

2021 ◽

Vol 58 (8) ◽

pp. 718-722

Author(s):

Sheeja Sugunan ◽

S. Bindusha ◽

S. Geetha ◽

H. R. Niyas ◽

A. Santhosh Kumar

Keyword(s):

Clinical Profile ◽

Short Term ◽

Term Outcome ◽

Pulse Methylprednisolone ◽

Short Term Outcome ◽

Inflammatory Syndrome

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Clinical Profile and Short-Term Outcome of Neonatal Seizures in a Tertiary Care Hospital, Kuppam – A Retrospective Study

Journal of Evidence Based Medicine and Healthcare ◽

10.18410/jebmh/2021/442 ◽

2021 ◽

Vol 8 (27) ◽

pp. 2381-2386

Author(s):

Poojitha Kancherla ◽

Harsha P.J. ◽

Gowtham R. ◽

Dowlath Anwar Basha ◽

Chandran G.P ◽

...

Keyword(s):

Tertiary Care ◽

Clinical Profile ◽

Hypoxic Ischemic Encephalopathy ◽

Care Hospital ◽

Neonatal Seizures ◽

Metabolic Disturbances ◽

Short Term ◽

Term Outcome ◽

Short Term Outcome ◽

Ischemic Encephalopathy

BACKGROUND Neonates presenting with seizures require long term stay in hospital and have higher chances of neuro-developmental delay later. Seizures in neonates are mostly subtle and difficult to diagnose. We wanted to study the clinical profile and short-term outcome on term and later pre-term neonates presenting with seizures. METHODS The study was a retrospective observational study done from November to December 2020 at PES Hospital, Kuppam. Retrospective data of neonatal seizures from May 2019 to April 2020 was considered for study. Details from the case records of neonates with seizures was collected. RESULTS Neonatal seizures (NS) were most common in females (53.8 %, 72/134). Subtle seizures were most common form of seizures in neonates which was seen in 64.2 % (86/134) babies followed by tonic seizures in 22.4 % (30/134). Neonatal seizures were most commonly seen in babies with hypoxic ischemic encephalopathy in 63.4 % (85/134) followed by metabolic disturbances in 15.6 % (21/134) and meningitis in 13.5 % (18/134). In babies with hypoxic ischemic encephalopathy, metabolic and meningitis subtle seizures were observed to be more common. Seizures were seen most commonly in first 72 hours of life (82.85 %, 111/134). Seizures in babies with hypoxic ischemic encephalopathy, metabolic causes most commonly occurred within first 24 hours of birth. Seizures in babies with meningitis most commonly occurred after 7 days of birth. Babies with neonatal seizures with sequelae was seen in 17.96 % (24/134) and 11.94 % babies died (16/134). CONCLUSIONS Subtle seizures were most common form and hypoxic ischemic encephalopathy was most common risk factor. Most neonatal seizures present within 72 hours of birth. Babies with meningitis presented with seizures most commonly after 72 hours of birth. KEYWORDS Hypoxic Ischemic Encephalopathy, Neonatal Seizures, Newborn, Aetiology, Outcome

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Refractory Status Epilepticus: Experience in a Neurological Intensive Care Unit

Journal of Critical Care Medicine ◽

10.1155/2014/821462 ◽

2014 ◽

Vol 2014 ◽

pp. 1-9 ◽

Cited By ~ 3

Author(s):

O. H. Hernandez ◽

J. F. Zapata ◽

M. Jimenez ◽

M. Massaro ◽

A. Guerra ◽

...

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Status Epilepticus ◽

Refractory Status Epilepticus ◽

Short Term ◽

Neurological Intensive Care Unit ◽

Term Outcome ◽

Neurological Intensive Care ◽

Refractory Status ◽

Short Term Outcome

Introduction. Refractory status epilepticus (RSE) has significant morbidity and mortality, and its management requires an accurate diagnosis and aggressive treatment. Objectives. To describe the experience of management of RSE in a neurological intensive care unit (NeuroICU) and determine predictors of short-term clinical outcome. Methods. We reviewed cases of RSE from September 2007 to December 2008. Management was titrated to findings on continuous video EEG (cVEEG). We collected patients’ demographics, RSE etiology, characteristics of seizures, cVEEG findings, treatments, and short-term outcome. Control of RSE was to achieve burst suppression pattern or electrographic cessation of ictal activity. Results. We included 80 patients; 63.8% were in coma, 25% had subclinical seizures, and 11.3% had focal activity. 51.3% were male and mean age was 45 years. Etiology was neurological lesion in 75.1%, uncontrolled epilepsy in 20%, and systemic derangements in 4.9%. 78.8% were treated with general anesthesia and concomitant anticonvulsant drugs. The control of RSE was 87.5% of patients. In-hospital mortality was 22.5%. The factors associated with unfavorable short-term outcome were coma and age over 60 years. Conclusions. RSE management guided by cVEEG is associated with a good seizure control. A multidisciplinary approach can help achieve a better short-term functional outcome in noncomatose patients.

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