A Study to Evaluate the Role of Dihydrotestosterone in the Pathogenesis of Benign Hyperplasia of Prostate and Prostatic Carcinoma in Patients Attending a Tertiary Care Hospital in Eastern India

This study aims to evaluate the sensitivity and specicity of CT in diagnosis of sinonasal diseases along with the spectrum of Paranasal sinus diseases oncomputerized tomography (CT) and correlate their clinical and histopathological ndings. 40patients who have undergone endoscopic sinus surgery, their relevant histopathological and surgical reports are included in Radiodiagnosis department of Nil Ratan Sircar Medical College. Chronic sinusitis has 100% sensitivity,94% specicity, 96% positive predictive value (PPV) and 100% negative predictive value (NPV). For fungal sinusitis the sensitivity was 66%,specicity was 97.4%, PPV 66% and NPV 97.4%. Polyps have sensitivity of 90.9%, specicity of 94%, PPV 90% and NPV 100% Benign neoplasms have sensitivity of 100%, specicity of 100%, PPV 100% and NPV 100%. CT may be used as gold standardimaging modality for evaluating the PNS diseases.

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A Study on the Role of Cartridge Based Nucleic Acid Amplification Test (CBNAAT) for Diagnosing Pediatric Tuberculosis in a Tertiary Care Hospital in Eastern India

Academic Journal of Pediatrics & Neonatology ◽

10.19080/ajpn.2018.06.555745 ◽

2018 ◽

Vol 6 (3) ◽

Author(s):

Kumar Anshu Suman Das

Keyword(s):

Nucleic Acid ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Nucleic Acid Amplification Test ◽

Nucleic Acid Amplification ◽

Care Hospital ◽

Eastern India ◽

Pediatric Tuberculosis

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TO DETERMINE THE ROLE OF CA125 IN THE DIAGNOSIS OF ACUTE APPENDICITIS

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v4i7.1276 ◽

2020 ◽

Vol 4 (7) ◽

Author(s):

Vinod Kumar ◽

Bhupen Songra ◽

Richa Jain ◽

Deeksha Mehta

Keyword(s):

Acute Appendicitis ◽

Clinical Diagnosis ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Ca 125 ◽

Care Hospital ◽

Serum Samples ◽

Roc Curve Analysis ◽

Surgery Department

Background: the present study was under taken to determine the role of CA-125 in the diagnosis of acute appendicitis (AA), to prevent its complications and also in preventing negative appendicectomies in tertiary care hospital. Methods: The study was conducted at a tertiary care and research center between 01/03/2018 to 30/06/2019. Patients admitted to the surgery department with diagnosis of AA were considered for the study. After informed consent, a, standardized history was obtained as a case Performa. Serum samples from all the cases with clinical diagnosis of AA were obtained and stored. Only the cases with histopathologically approved AA were included in the study. Cases operated for clinical diagnosis of AA, but not histopathologically proven AA was not included in the study. CA125 levels in cases with definitive diagnosis of AA were measured. Results: In present study, ROC curve analysis revealed the sensitivity of 87.27 % and specificity of 90.91 % when the CA 125 cut-off value of > 16.8 was taken to diagnose acute appendicitis. AUC was 0.911 with a standard error of 0.0292. Conclusion: In this study we have observed that CA125 showed a positive correlation with acute appendicitis, that was statistically not significant (P>0.05). We didn’t evaluate the correlation with the disease severity. We consider that CA125 can be used as a marker in acute appendicitis cases although further research is still needed. Keywords: CA125, Acute Appendicitis, Surgery.

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