scholarly journals A study on Quality of Life and Estimation of Biomarkers in COPD patients of a Tertiary Care Centre in Eastern Region

Author(s):  
Dr Soma Chakrabarti ◽  
Author(s):  
Aditya Kumar Gautam ◽  
Adesh Kumar ◽  
Ashish Kumar Gupta ◽  
Bal Krishna Kushwaha ◽  
Prashant Yadav ◽  
...  

Background: Chronic obstructive pulmonary disease COPD is a more complex systemic disease that has significant extra pulmonary effects along with pulmonary involvement. Complexity and mortality of COPD is increased by its co-morbidities and exacerbations. Depression is One of the commonest co-morbidity that occurs in patient with COPD and is associated with poor quality of life therefore we planned to assess depression among COPD patients.Methods: This was a cross-sectional study done in the respiratory medicine department of tertiary care centre, during the period from January 2015 to June 2016. A total of 200 patients of COPD of either sex having age more than 40 years included in the study. Patients who were critically ill and uncooperative excluded from the study. Patients who did not give consent and having previous history of any psychiatric illness also excluded from the study. The diagnosis of COPD was made on the basis of the clinical history, examination, X-ray chest and spirometry. Further, depression was evaluated with the validated Hindi version of nine items PHQ-9 (a subset of patient health questionnaire).Results: The data of all 200 COPD patients were analysed and it was observed that- prevalence of depression in COPD was found to be 49%. Prevalence was higher in male patients 147 (73.5%) as compared to female 53 (26.5%) patients in the present study. Minimal depression was found in 14.28 % COPD patients and mild depression in 25.51 % moderate depression in 39.79 % cases and severe depression in 20.40% cases.Conclusions: Symptoms of depression are common in patients with COPD and its presence may have significant impact on the quality of life of such patients and may be associated with a higher mortality rate.


Author(s):  
Manisha Sarkar

Background: Cervical cancer is one of many health care ironies. Better survival rates demand better quality of life (QoL). The aim of present study was to determine the change in QoL of cervical cancer patients due to treatment.Methods: An observational prospective study was conducted from July 2017 to June 2018 among 80 new cervical cancer patients without any prior history of treatment for cervical cancer, attending radiotherapy department of a tertiary care centre of West Bengal using a semi-structured schedule and European Organization for Research and Treatment of Cancer (EORTC) quality of life questionnaire (QLQ). Information was collected on socio-demographic and clinical aspects and QoL domains. Those with history of surgery for cervical cancer, advanced stage of disease were excluded. EORTC QLQ was administered at baseline and one month after completion of treatment. Data was analysed by percentage, means±standard deviation, range and Wilcoxon signed rank test etc. using SPSS-16.Results: Only 60 patients could be analysed as 10 patients died and 10 lost to follow-up. After treatment there was a significant improvement in global health, physical, emotional and cognitive functioning as well as decrease in symptoms like fatigue, pain, insomnia, appetite loss and constipation along with worsening of financial difficulties. There was significant improvement in body image, decrease in problems of symptom experience, peripheral neuropathy and menopausal symptoms after treatment.Conclusions: The cervical cancer patients show an overall improvement in their QoL in most of the domains after one month of treatment except worsening of financial difficulties. 


2019 ◽  
pp. 1-3
Author(s):  
Arun Philip

Among the side effects of cancer therapy, chemotherapy induced nausea and vomiting (CINV) is the most distressing and it affects the quality of life of patients and the treatment outcome. The study was undertaken to audit the adherence to antiemesis guidelines in the day care chemotherapy unit at our centre. Avast majority of our chemotherapies (85%) were high emetic risk regimes. We found that the adherence to anti-emesis guideline was 57%. Among the cases of non adherence, a majority were over-treated (57%). Looking into the reasons of non adherence, we feel the need to evolve our own population based guidelines. Improving public awareness about the toxicities of chemotherapy will help in dispelling unwanted fear of toxicity. Improving awareness about anti-emetic guidelines among clinicians also will play a major role in improving adherence to guidelines and thus improving outcome of therapy.


2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P79-P80
Author(s):  
Yahya Nasser Al Badaai ◽  
Mark Samaha

Objective 1) Determine the effect of surgical therapy for Chronic Rhinosinusitis (CRS) on patient quality of life in a tertiary care centre in Quebec. 2) Compare the outcome of endoscopic sinus surgery on patients with different comorbidities. Methods Prospective cohort study. Subjects were consecutive patients with a diagnosis of CRS who failed medical treatment and were undergoing Endoscopic Sinus Surgery (ESS). General health (SF-12 v2) and disease-specific (chronic sinusitis survey (CSS)) outcomes questionnaires were filled out pre-operatively and postoperatively. Results 152 patients were enrolled in a 7-month period. 120 patients completed the postoperative surveys. The most common co-morbidity was asthma (40%). 72% had clinical improvement, 12% worsened, and 15% were unchanged. The average improvement of CSS scores was 17%. Conclusions Significant improvement in quality of life was achieved after ESS for patients with CRS.


2020 ◽  
Vol 5 (3) ◽  
pp. S129
Author(s):  
A. RATHOON ◽  
V. Gurusamy ◽  
V. Ganesan ◽  
A. Srinivasan ◽  
Y. Chelikani ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document