scholarly journals Latent tetany and neuromuscular excitability

2018 ◽  
Vol 17 (2) ◽  
pp. 97-106
Author(s):  
Witold Kołłątaj ◽  
◽  
Barbara Kołłątaj ◽  
Maria Klatka ◽  
Iga Kapczuk ◽  
...  
Keyword(s):  
Neuromuscular Excitability

Fatigue-related changes in neuromuscular excitability of rat hindlimb muscles

1988 ◽  
Vol 11 (11) ◽  
pp. 1123-1132 ◽  
Author(s):  
Roger M. Enoka ◽  
Lucinda L. Rankin ◽  
Michael J. Joyner ◽  
Douglas G. Stuart
Keyword(s):  
Hindlimb Muscles ◽  
Neuromuscular Excitability

Neuromuscular excitability properties in myotonic dystrophy type 1

2007 ◽  
Vol 118 (11) ◽  
pp. 2375-2382 ◽  
Author(s):  
Delphine Boërio ◽  
Jean-Yves Hogrel ◽  
Guillaume Bassez ◽  
Jean-Pascal Lefaucheur
Keyword(s):  
Myotonic Dystrophy ◽  
Myotonic Dystrophy Type 1 ◽  
Myotonic Dystrophy Type ◽  
Neuromuscular Excitability

scholarly journals Neuromuscular excitability changes produced by sustained voluntary contraction and response to mexiletine in myotonia congenita

2017 ◽  
Vol 47 (3) ◽  
pp. 247-252 ◽  
Author(s):  
Federica Ginanneschi ◽  
Andrea Mignarri ◽  
Sabrina Lucchiari ◽  
Gianna Ulzi ◽  
Giacomo P. Comi ◽  
...  
Keyword(s):  
Voluntary Contraction ◽  
Myotonia Congenita ◽  
Neuromuscular Excitability

Changes in Neuromuscular Excitability in Vibration Disease

2003 ◽  
Vol 29 (6) ◽  
pp. 759-761
Author(s):  
E. N. Yan'shina ◽  
P. N. Lyubchenko ◽  
N. P. Yan'shin ◽  
N. D. Ovchinnikov ◽  
L. Ya. Abakumova
Keyword(s):  
Vibration Disease ◽  
Neuromuscular Excitability

scholarly journals SIR-2.1 integrates metabolic homeostasis with the reproductive neuromuscular excitability in early aging male Caenorhabditis elegans

eLife ◽  
2014 ◽  
Vol 3 ◽  
Author(s):  
Xiaoyan Guo ◽  
L René García
Keyword(s):  
Mating Behavior ◽  
Vas Deferens ◽  
Lipid Synthesis ◽  
Oxygen Species ◽  
Wild Type ◽  
Compensatory Response ◽  
C Elegans ◽  
Catabolic Enzymes ◽  
Neuromuscular Excitability ◽  
Ros Scavengers

The decline of aging C. elegans male’s mating behavior is correlated with the increased excitability of the cholinergic circuitry that executes copulation. In this study, we show that the mating circuits’ functional durability depends on the metabolic regulator SIR-2.1, a NAD+-dependent histone deacetylase. Aging sir-2.1(0) males display accelerated mating behavior decline due to premature hyperexcitability of cholinergic circuits used for intromission and ejaculation. In sir-2.1(0) males, the hypercontraction of the spicule-associated muscles pinch the vas deferens opening, thus blocking sperm release. The hyperexcitability is aggravated by reactive oxygen species (ROS). Our genetic, pharmacological, and behavioral analyses suggest that in sir-2.1(0) and older wild-type males, enhanced catabolic enzymes expression, coupled with the reduced expression of ROS-scavengers contribute to the behavioral decline. However, as a compensatory response to reduce altered catabolism/ROS production, anabolic enzymes expression levels are also increased, resulting in higher gluconeogenesis and lipid synthesis.

scholarly journals The I/T curve coefficient for evaluating changes in neuromuscular excitability after polarized light irradiation - a placebo-controlled randomized trial

2020 ◽  
Vol 24 (2) ◽  
Author(s):  
Jolanta Zwolińska
Keyword(s):  
Blue Light ◽  
Biceps Brachii ◽  
Pressure Pain Threshold ◽  
Light Irradiation ◽  
Test Material ◽  
Sensory Threshold ◽  
Blue Filter ◽  
Group I ◽  
Motor Excitability ◽  
Neuromuscular Excitability

Introduction: PILER light affects the sensory and motor excitability of the tissue, and these changes may depend on the color of the filter used in the irradiations. Objective: To evaluate changes in neuromuscular excitability after PILER irradiation with different filters. To evaluate the usefulness of the I/T curve coefficient in neuromuscular excitability test. Material and methods: 60 healthy volunteers assigned to four groups: group v - without filter (n=15), group x - red filter (n=15), group y - blue filter (n=15), group z - placebo (n=15) had biceps brachii irradiated with PILER light. Outcome Measures: I/T curve coefficient for rectangular (■I/T coeff) and triangular (▲I/T coeff) pulses for sensory and motor excitability and the pressure pain threshold (PPT). Results: ■I/T coeff (p=0.0013) and ▲I/T coeff (p=0.0011) for sensory excitability increased significantly in the irradiated group. ■I/T coeff (p=0.0356) and ▲I/T coeff (p=0.0022) increased significantly after blue light irradiation. A significant increase in the▲I/T coeff (p=0.0439) in motor excitability was observed in the irradiated group. ■I/T coeff (p=0.0309) and ▲I/T coeff (p=0.0064) increased significantly after blue light irradiation. Conclusion: PILER light may reduce muscle excitability. Using a blue filter may increase the sensory threshold, and myorelaxation. Further experiments are necessary to confirm the usefulness of the I/T curve coefficient.

scholarly journals Serotonin Syndrome and the Anaesthetist

2005 ◽  
Vol 33 (2) ◽  
pp. 181-187 ◽  
Author(s):  
D. Jones ◽  
D. A. Story
Keyword(s):  
Autonomic Dysfunction ◽  
Serotonin Syndrome ◽  
Clinical Manifestations ◽  
Conscious State ◽  
Muscle Relaxants ◽  
Serotonergic Activity ◽  
Neuromuscular Excitability ◽  
Recreational Use ◽  
Excessive Activation ◽  
Clinical Diagnostic Criteria

Serotonin syndrome results from excessive activation of serotonin (5-hydroxytryptamine; 5-HT) receptors in the nervous system, on the surface of platelets, and on the vascular endothelium. The clinical manifestations are a triad of altered conscious state, autonomic dysfunction, and neuromuscular excitability. Clinical diagnostic criteria remain poorly defined and unvalidated, and there are no available investigations to confirm the diagnosis. The syndrome is caused by the administration of one or more drugs possessing serotonergic activity. Severe forms of the syndrome usually result from overdose, but can be induced by monotherapy. The exact incidence of serotonin syndrome remains unknown, but is likely to be increasing due to increased prescription of selective serotonin reuptake inhibitor anti-depressants and tramadol, as well as recreational use of amphetamine-like substances. Serotonin syndrome may complicate the administration of drugs frequently used in anaesthetic practice, including pethidine and tramadol. Although the majority of cases improve with symptomatic and supportive care, severe cases need intensive care and frequently require mechanical ventilation. Neuromuscular excitability is likely to be the cause of rhabdomyolysis seen in severe cases and should be treated with benzodiazepines and muscle relaxants. Supportive therapies are required to treat hyperthermia and autonomic dysfunction. Cyproheptadine is the most commonly administered serotonergic antagonist, but is unavailable in parenteral form.

Effects of aspartic acid salts (Mg and K) on physical performance of men

1964 ◽  
Vol 19 (2) ◽  
pp. 257-261 ◽  
Author(s):  
C. Frank Consolazio ◽  
Richard A. Nelson ◽  
Le Roy O. Matoush ◽  
Gerhard J. Isaac
Keyword(s):  
Metabolic Rate ◽  
Aspartic Acid ◽  
Recovery Period ◽  
Convincing Evidence ◽  
Breath Holding ◽  
Moderate Exercise ◽  
Beneficial Effects ◽  
Fitness Index ◽  
Significant Difference ◽  
Neuromuscular Excitability

The performance of twelve men was measured during a 9-week study. Six of the men received placebos and six received 2 g of magnesium and potassium salts of aspartic acid (Spartase) daily during 5 weeks of therapy. There was no significant difference in metabolic rate and RQ between the control or aspartate supplemented groups during moderate exercise and the recovery period after moderate exercise. Differences in other factors, such as maximum breathing capacity, vital capacity, breath-holding time, etc., were also nonsignificant. A few significant differences appeared between groups for the neuromuscular excitability values, which because of their erratic pattern probably were due to chance. Under the stresses imposed in this study there seemed to be no convincing evidence of the beneficial effects of aspartate therapy. exercise; neuromuscular fatigue; metabolic rate, respiratory measurements and physical fitness index under aspartate therapy; ergogenic drugs Submitted on May 8, 1963

Monitoring high-intensity endurance training using neuromuscular excitability to recognize overtraining

1997 ◽  
Vol 76 (2) ◽  
pp. 187-191 ◽  
Author(s):  
M. Lehmann ◽  
S. Baur ◽  
N. Netzer ◽  
U. Gastmann
Keyword(s):  
Endurance Training ◽  
High Intensity ◽  
Neuromuscular Excitability
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