Resolution of the Council of experts on scientific experience exchange of antiplatelet drugs use, including acetylsalicylic acid for prevention of COVID-19 arterial vascular complications in different time periods of the disease

Therapy ◽  
2021 ◽  
Vol 9_2021 ◽  
pp. 113-124
Keyword(s):  
Acetylsalicylic Acid ◽  
Vascular Complications ◽  
Antiplatelet Drugs ◽  
Time Periods

scholarly journals Influence for functional outcome by different antiplatelet drugs; acetylsalicylic acid and cilostazol

Nosotchu ◽  
2014 ◽  
Vol 36 (6) ◽  
pp. 419-424
Author(s):  
Nobuaki Yamamoto ◽  
Junichiro Satomi ◽  
Yuka Terasawa ◽  
Shu Sogabe ◽  
Kohei Nakajima ◽  
...  
Keyword(s):  
Acetylsalicylic Acid ◽  
Functional Outcome ◽  
Antiplatelet Drugs

scholarly journals NMR spectroscopy reveals acetylsalicylic acid metabolites in the human urine for drug compliance monitoring

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0247102
Author(s):  
Galina Kupriyanova ◽  
Vladimir Rafalskiy ◽  
Ivan Mershiev ◽  
Ekaterina Moiseeva
Keyword(s):  
Cardiovascular Disease ◽  
Acetylsalicylic Acid ◽  
Acid Treatment ◽  
Cardiovascular Death ◽  
Antiplatelet Drugs ◽  
Resonance Spectroscopy ◽  
Compliance Monitoring ◽  
Drug Compliance ◽  
Acid Metabolites

Cardiovascular disease is the leading cause of morbidity and mortality worldwide. Long-term use of antiplatelet drugs is a well-studied therapy for the prevention of cardiovascular death. Ensuring compliance with lifelong administration of antiplatelet drugs, in particular acetylsalicylic acid, is one of the challenges of such therapy. The aim of this study is to explore the possibility of using nuclear magnetic resonance spectroscopy to identify acetylsalicylic acid metabolites in urine and to search for characteristic markers that could be used to detect patient compliance with long-term acetylsalicylic acid treatment.

scholarly journals Progress in Clinical Neurosciences: The ‘Antiplatelet’ Agents and the Role of the Endothelium

2007 ◽  
Vol 34 (3) ◽  
pp. 270-279 ◽  
Author(s):  
Farrah J. Mateen ◽  
Ashfaq Shuaib
Keyword(s):  
Cerebrovascular Disease ◽  
Acetylsalicylic Acid ◽  
Vessel Wall ◽  
Literature Search ◽  
Antiplatelet Agents ◽  
Antiplatelet Drugs ◽  
Important Mediator ◽  
Prevention And Treatment ◽  
Wall Interactions

The antiplatelet drugs, commonly used in the prevention and treatment of cerebrovascular disease, possess a number of effects that are independent of direct antiplatelet actions. Beneficial and detrimental effects both occur. The endothelium is an important mediator of these non-antiplatelet effects. We performed a literature search to locate articles related to acetylsalicylic acid (aspirin), clopidogrel, ticlopidine, and dipyridamole and the interactions of these medications with the endothelium. The role of each of the above medications is explored in relation to vasodilation, inflammation, oxidation, platelet-leukocyte interactions, and thrombogenic tendency via platelet-vessel wall interactions.

scholarly journals Long-term Prognosis of Vascular Access in Haemodialysis Patients with Systemic Lupus Erythematosus: A Retrospective Cohort Study

2020 ◽  
Author(s):  
Fan-Yu Chen ◽  
Chun-Fan Chen ◽  
Ann Charis Tan ◽  
Chia-Hao Chan ◽  
Fu-An Chen ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Vascular Complications ◽  
Incidence Rates ◽  
Systemic Lupus ◽  
Subdistribution Hazard ◽  
Significant Difference ◽  
Long Term Follow Up ◽  
Time Periods

Abstract Patients with systemic lupus erythematosus (SLE) have a higher risk of vascular complications. The objective of the study is to analyse the differences in the risk of arteriovenous fistula or graft (AVF/AVG) dysfunction in haemodialysis patients with and without SLE over a 10-year period. A final sample of 1366 SLE and 4098 non-SLE patients remained after propensity score matching. The outcome measure primarily evaluated is the incidence rate of AVF/AVG dysfunction. SLE patients had higher incidence rates of AVF/AVG dysfunction than non-SLE patients in all time periods. Three specific time periods that reached significant difference were the following: (1) after 1 year (incidence rates = 15.21, 13.01, respectively; subdistribution hazard ratio (SHR) = 1.15; P = 0.007), (2) 1st-to-10th-year period (incidence rates = 15.36 and 13.25, respectively; SHR = 1.16; P = 0.007), and (3) overall period (incidence rates = 23.53 and 21.66, respectively; SHR = 1.09; P = 0.027). In conclusion, there were significantly higher incidence rates of AVF/AVG dysfunction in SLE patients during the long-term follow-up period in this study.

V1157: Vascular Complications in Laparoscopic Urologic Procedures

2005 ◽  
Vol 173 (4S) ◽  
pp. 314-314
Author(s):  
Mirandolino B. Mariano ◽  
Rene J. Sotelo ◽  
Flavia Santinelli ◽  
Alejandro J. Garcia ◽  
Antonio Finelli ◽  
...  
Keyword(s):  
Vascular Complications

Symptomatic vascular complications after vascular closure device use following diagnostic and interventional catheterisation

VASA ◽  
2004 ◽  
Vol 33 (2) ◽  
pp. 78-81 ◽  
Author(s):  
Thalhammer ◽  
Aschwanden ◽  
Jeanneret ◽  
Labs ◽  
Jäger
Keyword(s):  
Current Literature ◽  
Vascular Complications ◽  
University Hospital ◽  
Closure Device ◽  
Ultrasound Guided ◽  
Vascular Closure Device ◽  
Device Use ◽  
Arterial Stenoses ◽  
The University ◽  
Stenotic Lesions

Background: Haemostatic puncture closure devices for rapid and effective hemostasis after arterial catheterisation are a comfortable alternative to manual compression. Implanting a collagen plug against the vessel wall may become responsible for other kind of vascular injuries i.e. thrombotic or stenotic lesions and peripheral embolisation. The aim of this paper is to report our clinically relevant vascular complications after Angio-Seal® and to discuss the results in the light of the current literature. Patients and methods: We report the symptomatic vascular complications in 17 of 7376 patients undergoing diagnostic or therapeutic catheterisation between May 2000 and March 2003 at the University Hospital Basel. Results: Most patients presented with ischaemic symptoms, arterial stenoses or occlusions and thrombotic lesions (n = 14), whereas pseudoaneurysms were extremely rare (n = 3). Most patients with ischaemic lesions underwent vascular surgery and all patients with a pseudoaneurysm were successfully treated by ultrasound-guided compression. Conclusions: Severe vascular complications after Angio-Seal® are rare, consistent with the current literature. There may be a shift from pseudoaneurysms to ischaemic lesions.

Paraoxonase-1 and myeloperoxidase correlate with vascular biomarkers in overweight patients with newly diagnosed untreated hyperlipidaemia

VASA ◽  
2017 ◽  
Vol 46 (5) ◽  
pp. 370-376 ◽  
Author(s):  
Anita Szentpéteri ◽  
Noémi Zsíros ◽  
Viktória E. Varga ◽  
Hajnalka Lőrincz ◽  
Mónika Katkó ◽  
...  
Keyword(s):  
Adhesion Molecule ◽  
Oxidized Ldl ◽  
Vascular Complications ◽  
Cd40 Ligand ◽  
Paraoxonase 1 ◽  
Intercellular Adhesion Molecule ◽  
Pon1 Activity ◽  
Intercellular Adhesion Molecule 1 ◽  
Inflammatory Parameters ◽  
Vascular Biomarkers

Abstract. Background: In hyperlipidaemic state, increased levels of myeloperoxidase (MPO) and decreased paraoxonase-1 (PON1) activity have been reported; however, their relationships with other atherosclerotic biomarkers have not been completely clarified. Patients and methods: Serum concentrations of lipid and inflammatory parameters, MPO levels, and PON1 activities were investigated in 167 untreated hyperlipidaemic patients with and without vascular complications and in 32 healthy controls. Additionally, levels of CD40 ligand (sCD40L) and asymmetric dimethyl arginine (ADMA), soluble intercellular adhesion molecule-1 (sICAM-1), soluble vascular cell adhesion molecule-1, and oxidized LDL were determined. Results: We found elevated C-reactive protein (CRP), ADMA, sCD40L, sICAM-1 concentrations, and higher MPO levels in patients with vascular complications compared to those without. The PON1 arylesterase activity correlated negatively with sCD40L, ADMA, and sICAM-1 levels, respectively. In contrast, MPO concentrations showed positive correlations with sCD40L, ADMA, and sICAM-1 levels, respectively. Conclusions: It can therefore be stated that PON1 activity and MPO level correlate strongly with the vascular biomarkers, highlighting the importance of the HDL-associated pro- and antioxidant enzymes in the development of endothelial dysfunction and atherogenesis.

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