scholarly journals The Ercc1-/Δ mouse model of accelerated senescence and aging for identification and testing of novel senotherapeutic interventions

Aging ◽  
2020 ◽  
Author(s):  
Alec Wong ◽  
Tra Kieu ◽  
Paul D. Robbins
2012 ◽  
Vol 53 (10) ◽  
pp. 6718 ◽  
Author(s):  
Mario Matthaei ◽  
Huan Meng ◽  
Alan K. Meeker ◽  
Charles G. Eberhart ◽  
Albert S. Jun

2018 ◽  
Vol 44 ◽  
pp. 292-298 ◽  
Author(s):  
Shoko Kushimoto ◽  
Yuki Uchibori ◽  
Shuichi Yanai ◽  
Hidefumi Makabe ◽  
Soichiro Nakamura ◽  
...  

2013 ◽  
Vol 257 ◽  
pp. 140-147 ◽  
Author(s):  
Yi Yang ◽  
Guang-yan Wu ◽  
Xuan Li ◽  
He Huang ◽  
Bo Hu ◽  
...  

2002 ◽  
Vol 57 (12) ◽  
pp. B415-B421 ◽  
Author(s):  
A. Shimada ◽  
H. Keino ◽  
M. Satoh ◽  
M. Kishikawa ◽  
N. Seriu ◽  
...  

Author(s):  
H. D. Geissinge ◽  
L.D. Rhodes

A recently discovered mouse model (‘mdx’) for muscular dystrophy in man may be of considerable interest, since the disease in ‘mdx’ mice is inherited by the same mode of inheritance (X-linked) as the human Duchenne (DMD) muscular dystrophy. Unlike DMD, which results in a situation in which the continual muscle destruction cannot keep up with abortive regenerative attempts of the musculature, and the sufferers of the disease die early, the disease in ‘mdx’ mice appears to be transient, and the mice do not die as a result of it. In fact, it has been reported that the severely damaged Tibialis anterior (TA) muscles of ‘mdx’ mice seem to display exceptionally good regenerative powers at 4-6 weeks, so much so, that these muscles are able to regenerate spontaneously up to their previous levels of physiological activity.


1998 ◽  
Vol 13 (11-s4) ◽  
pp. S178-S184 ◽  
Author(s):  
PETER KONTUREK ◽  
TOMASZ BRZOZOWSKI ◽  
STANISLAW KONTUREK ◽  
ELZBIETA KARCZEWSKA ◽  
ROBERT PAJDO ◽  
...  

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