scholarly journals Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer

Oncotarget ◽  
2018 ◽  
Vol 9 (37) ◽  
pp. 24787-24800 ◽  
Author(s):  
Yekaterina Y. Zaytseva ◽  
Piotr G. Rychahou ◽  
Anh-Thu Le ◽  
Timothy L. Scott ◽  
Robert M. Flight ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Fatty Acid ◽  
Cancer Cells ◽  
Fatty Acid Synthase ◽  
Xenograft Model ◽  
Primary Colorectal Cancer ◽  
Preclinical Evaluation ◽  
Patient Derived Xenograft ◽  
Colorectal Cancer Cells

scholarly journals Effects of olive oil polyphenols on fatty acid synthase gene expression and activity in human colorectal cancer cells

2010 ◽  
Vol 6 (1) ◽  
pp. 63-69 ◽  
Author(s):  
Maria Notarnicola ◽  
Simona Pisanti ◽  
Valeria Tutino ◽  
Domenica Bocale ◽  
Maria Teresa Rotelli ◽  
...  
Keyword(s):  
Gene Expression ◽  
Colorectal Cancer ◽  
Fatty Acid ◽  
Olive Oil ◽  
Cancer Cells ◽  
Fatty Acid Synthase ◽  
Human Colorectal Cancer ◽  
Colorectal Cancer Cells ◽  
Human Colorectal Cancer Cells ◽  
Expression And Activity

scholarly journals Inhibition of Fatty Acid Synthase Upregulates Expression of CD36 to Sustain Proliferation of Colorectal Cancer Cells

2020 ◽  
Vol 10 ◽  
Author(s):  
James Drury ◽  
Piotr G. Rychahou ◽  
Daheng He ◽  
Naser Jafari ◽  
Chi Wang ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Fatty Acid ◽  
Cancer Cells ◽  
Fatty Acid Synthase ◽  
Colorectal Cancer Cells

scholarly journals Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respiration

Oncotarget ◽  
2015 ◽  
Vol 6 (22) ◽  
pp. 18891-18904 ◽  
Author(s):  
Yekaterina Y. Zaytseva ◽  
Jennifer W. Harris ◽  
Mihail I. Mitov ◽  
Ji Tae Kim ◽  
D. Allan Butterfield ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Fatty Acid ◽  
Cancer Cells ◽  
Fatty Acid Synthase ◽  
Survival Advantage ◽  
Cellular Respiration ◽  
Colorectal Cancer Cells

scholarly journals Parthenolide suppresses tumor growth in a xenograft model of colorectal cancer cells by inducing mitochondrial dysfunction and apoptosis

2012 ◽  
Vol 41 (4) ◽  
pp. 1547-1553 ◽  
Author(s):  
SE-LIM KIM ◽  
KIEU THE THU TRANG ◽  
SEONG HUN KIM ◽  
IN HEE KIM ◽  
SEUNG OK LEE ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Tumor Growth ◽  
Mitochondrial Dysfunction ◽  
Cancer Cells ◽  
Xenograft Model ◽  
Colorectal Cancer Cells
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