scholarly journals Spatial Data Analysis in epidemiology of sensorineural hearing loss

2020 ◽  
Vol 19 (4) ◽  
pp. 13-20
Author(s):  
A. A. Korneenkov ◽  
◽  
S. V. Ryazantsev ◽  
I. V. Fanta ◽  
E. E. Vyazemskaya ◽  
...  

The identification of risk factors, features and patterns of the emergence and spread of diseases in space requires a large array of diverse data and the use of a serious mathematical and statistical apparatus. The distribution of diseases in space is studied using spatial analysis tools, which are now widely used as information systems are introduced and data are accumulated that are relevant to public health. For most tasks of working with spatial data (data, events that have geographical, spatial coordinates), various geographic information systems are used. As a disease for spatial analysis, sensorineural hearing loss was chosen, with which patients were treated at the Saint-Petersburg Research of Ear, Throat, Nose and Speech during one year of the study. The main tasks of the spatial analysis of data on the incidence of sensorineural hearing loss (SNHL) for hospitalization were: visualization of a point pattern, which can form the geographical coordinates of the places of residence of inpatients with SNHL; assessment of the properties of the spatial process that generates this point image (assessment of the intensity of the process, its laws) using various statistical indicators; testing the hypothesis about the spatial randomness of this process and the influence of individual factors on it. R-code accompanied all calculations in the article. Calculations can be reproduced quite easily. The text of the article can be used as step-by-step instructions for their implementation.

2021 ◽  
Vol 20 (3) ◽  
pp. 39-50
Author(s):  
A. A. Korneenkov ◽  
◽  
S. V. Ryazantsev ◽  
S. V. Levin ◽  
A. V. Khramov ◽  
...  

The aim of the study is a spatial and statistical analysis of hearing loss of various types (conductive, sensorineural, mixed) and deafness in the adult population of the Chelyabinsk region, assessment of its dynamics and the impact of environmental stress in the place of residence. The study materials were data from the regional audiological center of the Chelyabinsk regional clinical hospital for the period from 2016–2020. Epidemiological issues of the spread of diseases were studied using the methods of spatial analysis, in the R software environment. The main tasks of spatial analysis were to visualize a point pattern from the geographical coordinates of the patient’s places of residence, assess the properties of the spatial process that generates this point pattern, test the hypothesis about the spatial randomness of this process and the influence of the ecological situation on it. It was found that more than half of all primary visits were patients with bilateral sensorineural hearing loss. The number of patients who applied for the year during the observation period fluctuates within the average. Of all hearing impairments, the highest values of relative incidence are characteristic of sensorineural hearing loss, which has a direct relationship with age. The intensity of detection in patients with hearing impairment and deafness is directly related to the size of the living population. The existing division into zones with different ecological situations does not have a statistically significant (p <0.05) effect on the ratio of the number of patients with hearing impairments to the population.


2021 ◽  
Vol 104 (2) ◽  
pp. 260-263

Background: Bacterial meningitis is one of the major factors in the etiology of acquired sensorineural hearing loss in children and adults. Cochlear implantation in these patients is challenging because of inner ear ossification and fibrosis, and this procedure sometimes achieves poorer outcomes in this scenario than with other causes of sensorineural hearing loss. There has been little research into the factors affecting the outcomes of this procedure. Objective: To evaluate the outcomes of cochlear implantation in patients with postmeningitis profound sensorineural hearing loss and to evaluate the factors that affect the results. Materials and Methods: A retrospective review was conducted of thirty patients who were diagnosed with post meningitis profound hearing loss and underwent cochlear implantation at Rajavithi Hospital between 2001 and 2016. Preoperative language status, duration of deafness, preoperative imaging, and degree of electrode insertion were recorded. Categories of auditory performance-II test (CAP-II) was evaluated in all cases, one year postoperative. Results: Thirty postmeningitis deafness patients underwent cochlear implantation. The median age at diagnosis of meningitis and age at implantation were 41 years (range 1 to 75) and 49.50 years (range 3 to 75), respectively. The median duration of deafness was 12 months (range 4 to 300), and the overall mean CAP-II at one year after surgery was 5.47±2.21. The postlinguistic group had a significantly higher CAP-II score than the prelinguistic one (p=0.006). Electrodes were successfully totally inserted in 19 patients (63.3%) and partially inserted in 11 (36.7%). The average CAP-II score in the group with fully-inserted electrodes was significantly higher than in the group with partially-inserted electrodes (p=0.045). There was no correlation between CAP-II score and age at meningitis diagnosis (p=0.069), age at time of surgery (p=0.105), duration of deafness (p=0.506), or preoperative CT (p=0.228) or MRI abnormality (p=0.078). Conclusion: Cochlear implantation in patients with postmeningitis profound hearing loss had high success rates and favorable outcomes. Preoperative language status and degree of electrode insertion were factors that affected auditory performance results. Keywords: Cochlear implantation, Postmeningitis hearing loss, Sensorineural hearing loss, Meningitis, Rajavithi Hospital


2006 ◽  
Vol 120 (9) ◽  
pp. 718-724 ◽  
Author(s):  
J Xenellis ◽  
I Karapatsas ◽  
N Papadimitriou ◽  
T Nikolopoulos ◽  
P Maragoudakis ◽  
...  

Objectives: Sudden sensorineural hearing loss (SSHL) remains a challenge for the clinician. In the majority of cases, no definite cause can be found and the prognosis is variable.Methods: The present study assessed 114 patients suffering from idiopathic SSHL, with regard to the prognostic value of demographic, epidemiologic, neurotologic and audiometric factors. In addition, the relationship between the identification of wave V in auditory brainstem responses and the final hearing outcome was investigated. All patients received 75 mg/day intravenous prednisolone, divided into three daily doses, for 10 days, with gradual tapering of the dose over the next 10 days.Results: The results (after one year follow up) revealed the following factors to be related to a better hearing outcome: younger age; male sex; less time elapsed between the onset of hearing loss and the beginning of treatment; and an upward-sloping or cupeloid audiogram contour. The detection of wave V early in recovery and within the first month of medical treatment might also constitute a significant favourable factor in respect to hearing recovery.Conclusions: The present study revealed that there are certain factors that affect prognosis in idiopathic SSHL. This is very important in counselling patients and may affect current clinical practice.


Akustika ◽  
2021 ◽  
pp. 189
Author(s):  
Aleksei Korneenkov ◽  
Sergey Ryazantsev ◽  
Alexei Khramov ◽  
Sergey Levin

The goal of the study was a spatial analysis of the morbidity of hearing loss of various types in the adult population of Chelyabinsk Region and the dependence of the incidence on the environmental issues at the place of residence. The epidemiological issues of the localization of hearing disorders were studied by spatial analysis in the R software environment. The main tasks of the spatial analysis were to produce a visualization, in the form of a point pattern, of the geographical coordinates of the patients’ places of residence, evaluate the properties of the spatial process that generates the point pattern, and test the hypothesis about the influence of the environmental situation on the indicator. The existing division into zones with different environmental situations, in general, does not have a statistically significant (p<0.05) effect on the ratio of the number of patients with hearing loss to the population of the district. However, statistically significant differences (p<0.05) of this indicator were found between areas with a critical and severe environmental situation, as well as between those with a critical and provisionally satisfactory situation. No statistically significant differences were found between the other regions (p>0.05).


1999 ◽  
Vol 113 (12) ◽  
pp. 1098-1100 ◽  
Author(s):  
I. Hore ◽  
R. B. Mitchell ◽  
G. Radcliffe ◽  
R. Quiney ◽  
T. Walker

AbstractLangerhans' cell histiocytosis is a rare disorder of unknown aetiology in which pathological Langerhans' cells accumulate and destroy local tissue. We report a 38-year-old female who presented with a sudden onset of left sensormeural hearing loss. Magnetic resonance imaging (MRI) revealed a contrast-enhancing lesion in the left mastoid and a second lesion in the hypothalamus. Following left mastoid exploration and biopsy a definitive diagnosis of Langerhans' cell histiocytosis was made and the patient was treated with external beam radiotherapy. Subsequent right femur and right mastoid involvement were successfully treated with steroids and cytotoxic chemotherapy. At one year follow-up the patient had residual left-sided sensorineural hearing loss with normal hearing in the right ear. To our knowledge, Langerhans' cell histiocytosis has not been previously reported as a cause of unilateral sudden onset sensorineural hearing loss. It should be considered in the differential diagnosis of this condition.


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