Spatial and statistical analysis of hearing impairment data of Chelyabinsk region residents

2021 ◽  
Vol 20 (3) ◽  
pp. 39-50
Author(s):  
A. A. Korneenkov ◽  
◽  
S. V. Ryazantsev ◽  
S. V. Levin ◽  
A. V. Khramov ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Statistical Analysis ◽  
Spatial Analysis ◽  
Sensorineural Hearing Loss ◽  
Hearing Impairment ◽  
Sensorineural Hearing ◽  
Point Pattern ◽  
Hearing Impairments ◽  
Number Of Patients ◽  
Chelyabinsk Region

The aim of the study is a spatial and statistical analysis of hearing loss of various types (conductive, sensorineural, mixed) and deafness in the adult population of the Chelyabinsk region, assessment of its dynamics and the impact of environmental stress in the place of residence. The study materials were data from the regional audiological center of the Chelyabinsk regional clinical hospital for the period from 2016–2020. Epidemiological issues of the spread of diseases were studied using the methods of spatial analysis, in the R software environment. The main tasks of spatial analysis were to visualize a point pattern from the geographical coordinates of the patient’s places of residence, assess the properties of the spatial process that generates this point pattern, test the hypothesis about the spatial randomness of this process and the influence of the ecological situation on it. It was found that more than half of all primary visits were patients with bilateral sensorineural hearing loss. The number of patients who applied for the year during the observation period fluctuates within the average. Of all hearing impairments, the highest values of relative incidence are characteristic of sensorineural hearing loss, which has a direct relationship with age. The intensity of detection in patients with hearing impairment and deafness is directly related to the size of the living population. The existing division into zones with different ecological situations does not have a statistically significant (p <0.05) effect on the ratio of the number of patients with hearing impairments to the population.

ENVIRONMENTAL FACTOR IN THE SPATIAL ANALYSIS OF HEARING IMPAIRMENTS IN RESIDENTS OF THE CHALYABINSK REGION

Akustika ◽  
2021 ◽  
pp. 189
Author(s):  
Aleksei Korneenkov ◽  
Sergey Ryazantsev ◽  
Alexei Khramov ◽  
Sergey Levin
Keyword(s):  
Hearing Loss ◽  
Spatial Analysis ◽  
Adult Population ◽  
Point Pattern ◽  
Spatial Process ◽  
Hearing Impairments ◽  
Software Environment ◽  
Environmental Situation ◽  
Number Of Patients ◽  
Chelyabinsk Region

The goal of the study was a spatial analysis of the morbidity of hearing loss of various types in the adult population of Chelyabinsk Region and the dependence of the incidence on the environmental issues at the place of residence. The epidemiological issues of the localization of hearing disorders were studied by spatial analysis in the R software environment. The main tasks of the spatial analysis were to produce a visualization, in the form of a point pattern, of the geographical coordinates of the patients’ places of residence, evaluate the properties of the spatial process that generates the point pattern, and test the hypothesis about the influence of the environmental situation on the indicator. The existing division into zones with different environmental situations, in general, does not have a statistically significant (p<0.05) effect on the ratio of the number of patients with hearing loss to the population of the district. However, statistically significant differences (p<0.05) of this indicator were found between areas with a critical and severe environmental situation, as well as between those with a critical and provisionally satisfactory situation. No statistically significant differences were found between the other regions (p>0.05).

scholarly journals Spatial Data Analysis in epidemiology of sensorineural hearing loss

2020 ◽  
Vol 19 (4) ◽  
pp. 13-20
Author(s):  
A. A. Korneenkov ◽  
◽  
S. V. Ryazantsev ◽  
I. V. Fanta ◽  
E. E. Vyazemskaya ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Information Systems ◽  
Spatial Analysis ◽  
Sensorineural Hearing Loss ◽  
Spatial Data ◽  
Sensorineural Hearing ◽  
Spatial Data Analysis ◽  
Point Pattern ◽  
Spatial Process ◽  
One Year

The identification of risk factors, features and patterns of the emergence and spread of diseases in space requires a large array of diverse data and the use of a serious mathematical and statistical apparatus. The distribution of diseases in space is studied using spatial analysis tools, which are now widely used as information systems are introduced and data are accumulated that are relevant to public health. For most tasks of working with spatial data (data, events that have geographical, spatial coordinates), various geographic information systems are used. As a disease for spatial analysis, sensorineural hearing loss was chosen, with which patients were treated at the Saint-Petersburg Research of Ear, Throat, Nose and Speech during one year of the study. The main tasks of the spatial analysis of data on the incidence of sensorineural hearing loss (SNHL) for hospitalization were: visualization of a point pattern, which can form the geographical coordinates of the places of residence of inpatients with SNHL; assessment of the properties of the spatial process that generates this point image (assessment of the intensity of the process, its laws) using various statistical indicators; testing the hypothesis about the spatial randomness of this process and the influence of individual factors on it. R-code accompanied all calculations in the article. Calculations can be reproduced quite easily. The text of the article can be used as step-by-step instructions for their implementation.

scholarly journals Novel USH1G homozygous variant underlying USH2-like phenotype of Usher syndrome

2019 ◽  
pp. 112067211987939
Author(s):  
Fabiana D’Esposito ◽  
Viviana Randazzo ◽  
Gilda Cennamo ◽  
Nicola Centore ◽  
Paolo Enrico Maltese ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Retinitis Pigmentosa ◽  
Sensorineural Hearing Loss ◽  
Hearing Impairment ◽  
Usher Syndrome ◽  
Age At Onset ◽  
Vestibular Dysfunction ◽  
Sensorineural Hearing ◽  
Type I ◽  
Missense Variation

Purpose: Usher syndrome (USH) is an autosomal recessive disorder characterized by congenital sensorineural hearing impairment and retinitis pigmentosa. Classification distinguishes three clinical types of which type I (USH1) is the most severe, with vestibular dysfunction as an added feature. To date, 15 genes and 3 loci have been identified with the USH1G gene being an uncommon cause of USH. We describe an atypical USH1G-related phenotype caused by a novel homozygous missense variation in a patient with profound hearing impairment and relatively mild retinitis pigmentosa, but no vestibular dysfunction. Methods: A 26-year-old female patient with profound congenital sensorineural hearing loss, nyctalopia and retinitis pigmentosa was studied. Audiometric, vestibular and ophthalmologic examination was performed. A panel of 13 genes was tested by next-generation sequencing (NGS). Results: While the hearing loss was confirmed to be profound, the vestibular function resulted normal. Although typical retinitis pigmentosa was present, the age at onset was unusually late for USH1 syndrome. A novel homozygous missense variation (c.1187T>A, p.Leu396Gln) in the USH1G gene has been identified as causing the disease in our patient. Conclusions: Genetic and phenotypic heterogeneity are very common in both isolated and syndromic retinal dystrophies and sensorineural hearing loss. Our findings widen the spectrum of USH allelic disorders and strength the concept that variants in genes that are classically known as underlying one specific clinical USH subtype might result in unexpected phenotypes.

Otosclerosis: Vestibular Symptoms and Sensorineural Hearing Loss

1978 ◽  
Vol 87 (6) ◽  
pp. 778-796 ◽  
Author(s):  
D. Thane R. Cody ◽  
Hillier L. Baker
Keyword(s):  
Vitamin D ◽  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Sodium Fluoride ◽  
Calcium Gluconate ◽  
Sensorineural Hearing ◽  
Caloric Test ◽  
Number Of Patients ◽  
Vestibular Symptoms ◽  
Preliminary Study

Of 546 patients with otosclerosis, 500 who had not had ear surgery were divided into four groups according to the relative and absolute amounts of sensorineural hearing loss in the hearing-impaired ears. The first three groups of patients had progressively less of a conductive component and progressively more of a sensorineural component to their hearing losses. The fourth group of patients had pure sensorineural hearing impairments. The remaining 46 patients were placed in group V. They had bilateral hearing losses and had had a prior unilateral stapedectomy for otosclerosis and they had received medical therapy for otosclerosis. The following conclusions were reached: 1 Further clinical evidence was obtained supporting the existence of the entity “pure labyrinthine otosclerosis.” However, there can be difficulties in the diagnosis of this condition. 2 The incidence of vestibular symptoms in patients with otosclerosis increased as the relative and absolute amounts of sensorineural hearing loss increased and was much higher than one would expect in the normal population. In addition, with increasing sensorineural hearing loss, the severity of vestibular symptoms increased along with the incidence of depression in vestibular function determined by the bithermal caloric test in patients with vestibular Symptoms. 3 A preliminary study on the administration of a combination of calcium gluconate, sodium fluoride, and vitamin D to patients with otosclerosis who had vestibular symptoms indicated that the therapy controlled vestibular symptoms in a high percentage of these patients. 4 A preliminary study on the administration of calcium gluconate, sodium fluoride, and vitamin D to patients with otosclerosis indicated that in a high percentage of patients the deterioration in hearing was stopped. A small but significant number of patients had reversal of their hearing loss. 5 Side effects of treatment with a combination of calcium gluconate, sodium fluoride, and vitamin D were not serious and were reversible, and there appears to be no contraindication to this therapy for healthy adults.

Acupuncture and Sensorineural Hearing Loss: A Review

1975 ◽  
Vol 40 (4) ◽  
pp. 427-433 ◽  
Author(s):  
Harvey A. Taub
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Hearing Impairment ◽  
Placebo Effect ◽  
Sensorineural Hearing ◽  
Hearing Ability ◽  
Sensorineural Hearing Impairment

Recent reports concerning the use of acupuncture as a possible treatment for sensorineural hearing impairment were reviewed and evaluated. It was concluded that acupuncture has no effect upon the hearing ability of individuals with sensorineural losses. Further, it was suggested that subjective feelings of improvement represent a placebo effect resulting from the application of a treatment that patients believe might work and not from acupuncture itself.

scholarly journals Statistical Analysis on the Prognosis of Sudden Sensorineural Hearing Loss

2004 ◽  
Vol 47 (2) ◽  
pp. 87-91 ◽  
Author(s):  
Shigeru Kuwashima ◽  
Toshihiko Abe ◽  
Naonori Sato ◽  
Hiroaki Sato ◽  
Kazuo Murai
Keyword(s):  
Hearing Loss ◽  
Statistical Analysis ◽  
Sensorineural Hearing Loss ◽  
Sudden Sensorineural Hearing Loss ◽  
Sensorineural Hearing

scholarly journals Effects of Radiotherapy on Auditory and Vestibular Function

2014 ◽  
Vol 6 (4) ◽  
pp. 1-5
Author(s):  
Sachin Sharad Nilakhe
Keyword(s):  
Hearing Loss ◽  
Radiation Therapy ◽  
Sensorineural Hearing Loss ◽  
Head And Neck ◽  
Conductive Hearing Loss ◽  
Vestibular Dysfunction ◽  
Sensorineural Hearing ◽  
Head And Neck Malignancies ◽  
Number Of Patients ◽  
Conductive Hearing

ABSTRACT Introduction Radiotherapy either primary or adjuvant, is a commonly used modality of treatment in head and neck malignancies. The audiovestibular apparatus is often within the fields of radiation treatment, and hearing loss is a possible complication. This study was undertaken to assess the audiovestibular functions in patients undergoing radiation therapy for head and neck malignancies to determine the type and severity of hearing loss and vestibular dysfunction following radiation therapy. Materials and methods Fifty patients with head and neck malignancies reported to the malignant disease treatment center of INHS Asvini and received radiotherapy as a primary modality of treatment or in combination with surgery during the period May 2003 to Sep 2004 were included in this study. None of these patients had prior treatment by chemotherapy. Conclusion A significant number of patients who were subjected to radiation therapy for head and neck malignancies develop conductive hearing loss is predominant in the immediate postradiation period. Conductive hearing loss is reversible and improves with the conservative line of treatment. Sensorineural hearing loss more commonly affects the higher frequencies and is more common in older patients. Sensorineural hearing loss is more common when radiation doses exceed 60 Gy. There is no conclusive evidence of vestibular dysfunction in patients undergoing radiotherapy for head and neck cancers.

scholarly journals Sensorineural Hearing Loss: What Lies Beneath? Neurovascular Conflict Secondary to a Dural Arteriovenous Malformation

2014 ◽  
Vol 29 (2) ◽  
pp. 37-38
Author(s):  
Ian C. Bickle
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Hearing Impairment ◽  
Sensorineural Hearing ◽  
Assessment Process ◽  
External Carotid ◽  
Neurovascular Conflict ◽  
Vestibulocochlear Nerve ◽  
Presenting Symptoms ◽  
Wide Range

This middle-aged gentleman with no previous medical history presented to the local ENT outpatient clinic complaining of right-sided hearing loss.  No history of trauma or previous head and neck surgery was elicited. Following clinical and auditory assessment a right sensorineural hearing loss was confirmed.  A right-sided facial palsy was additionally identified on examination. A MRI of the internal auditory meati was performed (Figure 1a & 1b).  Following radiologist review, MRI and MRA of the brain was undertaken.   DISCUSSION   Auditory impairment is a condition with a legion of potential causes. One of the routine aspects of the assessment process for those with sensorineural hearing loss is MR imaging (MRI) of the internal auditory meati (IAMS).   The vast majority of MRI studies are normal, however one of the more commonly identified pathologies are cerebrovascular abnormalities. The most well recognised is neurovascular conflict of the vestibulocochlear nerve by a vascular loop at the root entry zone (REZ), however a broader range of potential responsible structural abnormalities are known. A wide range of processes for auditory dysfunction have been outlined.1 These include; cerebral ischaemia events, subarachnoid haemorrhage, cerebrovascular malformations and rarely dural arteriovenous fistulas (dAVFs).   Dural AVF's are abnormal vascular communications between the dural venous sinuses and an arter(ies) - most frequently branches of the external carotid artery. Sensorineural hearing impairment is one of the rarer presenting symptoms. The mechanism for hearing impairment is believed to result from either direct vascular compression on the vestibulocochlear nerve from an enlarged aberrant draining vein or from a vascular steal phenomenon (Figures 2a & 2b). An engorged draining vein from the dAVF causing mechanical compression on the nerve is the most well recognized.2 A single prior case has been reported of compression from an intraossesous dAVF of the skull base.3   The arteriovenous fistula may be directed identified (Figure 3) along with the associated signs of enlarged cerebral cortical veins and white matter change of venous hypertension (Figure 4).  

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