scholarly journals DETECÇÃO DE REGIÕES SUSPEITAS DE LESÃO NA MAMA EM IMAGENS TÉRMICAS UTILIZANDO SPATIOGRAM E REDES NEURAIS

2013 ◽  
Vol 20 (2) ◽  
pp. 56 ◽  
Author(s):  
Paulo Sérgior Aguiar Junior ◽  
Caio Nogueira Silva Belfort ◽  
Aristófanes Corrêa Silva ◽  
Pedro Henrique Bandeira Diniz ◽  
Rita de Cassia Fernandes de Lima ◽  
...  

Este trabalho propõe uma metodologia para identificar regiões suspeitas de lesão baseada nas assime-trias da mama esquerda e direita de imagens de termogramas. O estudo é pautado em imagens de pacientes do Hospital Universitário da Universidade Federal de Pernambuco (UFPE), capturadas por câmera infravermelha. Inicialmente as imagens são manualmente segmentadas. Em seguida, os seios são registrados usando a transformação B-spline. Além disso, como o corpo humano tem uma simetria radial das temperaturas, uma lesão, eventualmente, leva uma assimetria destas regiões, em seguida, o spatiogram é usado para identificar essas regiões assimétricas. Finalmente, apenas as regiões com temperaturas superiores à média são mantidas, com base no fato de que o câncer tem a temperatura mais elevada do que o restante mama. Após esse processo são extraídas características (Variação dos pixels, a média, o desvio padrão, o índice de Geary e Dimensão Fractal de Higuchi) para a classificação dessas regiões restantes em lesão ou não lesão utilizando-se uma rede neural artificial com perceptron em multicamadas. A metodologia apresentou 75% das regiões classificadas corretamente, indicando que o spatiogram e a média das temperaturas das regiões assimétricas são métodos bem promissores para identificação de regiões suspeitas de conter lesão.Palavras-chave: Termografia. Câncer. Spatiogram. Mama. Rede-neural.SUSPECT DETECTION OF REGIONS OF INJURY IN BREAST IN THERMAL IM-AGES USING SPATIOGRAM AND NEURAL NETWORKSAbstract: This paper proposes a methodology to identify suspicious regions of injury based on asymmetries of left and right breasts of thermograms images.. The study is based on images captured by infrared camera from patients at the University Hospital of the Federal University of Pernambuco. Initially the images are manually segmented. Then, the sinuses are recorded using the B-spline transformation. Furthermore, as the human body has a radial symmetry of temperatures, damage eventually leads asymmetry of these regions, then the spatiogram is used to identify those asymmetric.regions. Finally, only the regions with higher than average temperatures are maintained, based on the fact that the cancer has a higher temperature than the rest of the breast. After this process features are extracted (Variation of pixels, the mean, standard deviation, index Geary and Higuchi Fractal Dimension) for the classification of regions remaining in injury or no injury using an artificial neural network Multilayer perceptron. The methodology showed 75% of correctly classified regions, indicating that the spatiogram and the average temperatures of the asymmetric regions are well promises methods to identify regions suspected of containing lesion.Keywords: Thermography. Cancer. Spatiogram. Breast. Neural-network.DETECCIÓN DE ZONAS SOSPECHOSAS DE LESIÓN EN LA MAMA EN IMÁGENES TÉRMICAS UTILIZANDO SPATIOGRAM Y REDES NEURALESResumen: En este trabajo se propone una metodología para identificar las regiones sospechosas de lesión basado en las asimetrías de la mama izquierda y derecha de las imágenes termogramas. El estudio se basa en las imágenes capturadas por la cámara infrarroja de los pacientes en el Hospital Universitario de la Universidade Federal de Pernambuco. Inicialmente, las imágenes son segmentadas manualmente. Luego, los senos se registran utilizando la transformación B-spline. Además, como el cuerpo humano tiene  una simetría radial de temperaturas, daños eventualmente conducen a una asimetría de estas regiones, entonces el spatiogram se utiliza para identificar las regiones asimétricas. Finalmente, basado en el hecho de  que el cáncer tiene una temperatura más alta que el resto de la mama, sólo las regiones con temperaturas más alta que la temperatura media son mantenidas. Después de este proceso se extraen características (Variación de píxeles, la media, desviación estándar, Dimensión índice y Higuchi Geary fractal) para la clasificación de las regiones restantes en lesiones o ninguna lesión utilizando un perceptrón multicapa red neural artificial. La metodología mostró 75% regiones clasificados correctamente, lo que indica que las temperaturas spatiogram y media de las regiones son métodos asimétricos bien promete para identificar regiones sospechosas de contener lesión.Palabras clave: Termografía. Cáncer. Spatiogram. Mama. Redes neuronales.

2015 ◽  
Vol 11 (3) ◽  
pp. 518-524 ◽  
Author(s):  
Sabine Schmidt-Weitmann ◽  
Urs Schulz ◽  
Daniel Max Schmid ◽  
Christiane Brockes

The University Hospital of Zurich offers a text-based, Medical Online Consultation Service to the public since 1999. Users asked health questions anonymously to tele-doctors. This study focused on the characteristics of male enquirers with intimate health problems, the content of their questions, the medical advice given by tele-doctors and the rating of the service to prove the benefit of an online service for medical laymen. This retrospective study included 5.1% of 3,305 enquiries from 2008 to 2010 using the International Classification of Diseases-10 and International Classification of Primary Care codes relevant for intimate and sexual health problems in men. A professional text analysis program (MAXQDA) supported the content analysis, which is based on the procedure of inductive category development described by Mayring. The average age was 40 years, 63.1% enquirers had no comorbidity, in 62.5% it was the first time they consulted a doctor, and 70.2% asked for a specific, single, intimate health issue. In 64.3%, the most important organ of concern was the penis. Overall, 30.4% asked about sexually transmitted diseases. In 74.4% a doctor visit was recommended to clarify the health issue. The rating of the problem solving was very good. The service was mainly used by younger men without comorbidity and no previous contact with a doctor with regard to an intimate health problem. The anonymous setting of the teleconsultation provided men individual, professional medical advice and decision support. Teleconsultation is suggested to empower patients by developing more health literacy.


2019 ◽  
Vol 18 (4) ◽  
pp. 489
Author(s):  
Serena Cocca ◽  
Massimo Viviano ◽  
Michele Loglisci ◽  
Stefano Parrini ◽  
Giovanni Monciatti ◽  
...  

Objectives: Rett syndrome (RS) is a severe neurological developmental disorder characterised by stereotypical hand movements, epileptic seizures, craniofacial dysmorphism and digestive dysfunction. This study aimed to examine the correlation between the severity of malocclusion and dysphagia in patients with RS. Methods: This preliminary study was conducted at the Ear, Nose & Throat Clinic of the University Hospital of Siena, Siena, Italy, from January 2014 to December 2017. A total of 56 patients with RS were examined and grouped according to the severity of dysphagia (absent, mild, moderate or severe) and malocclusion (<2 mm, 2–3 mm, 3–4 mm or >4 mm). Results: All of the patients were female and the mean age was 11.3 years. Eight (14.3%) patients had mild, 18 (32.1%) had moderate and 30 (53.6%) had severe dysphagia. Four (7.1%) patients had <2 mm occlusion, 10 (17.9%) had 2–3 mm occlusion, 26 (46.4%) had 3–4 mm occlusion and 16 (28.6%) had >4 mm occlusion. Mild dysphagia was observed in 100% and 40% of patients with <2 and 2–3 mm malocclusion, respectively, while moderate dysphagia was present in 60% and 38.5% of patients with 2–3 and 3–4 mm malocclusion, respectively. Severe dysphagia was observed in 28.6% and 87.5% of patients with 3–4 and >4 mm malocclusion, respectively. There was a significant correlation between dysphagia and malocclusion severity (P <0.001). Conclusion: A higher degree of malocclusion was associated with more severe dysphagia among a cohort of patients with RS.Keywords: X-Linked Mental Retardation; Rett Syndrome; Dysphagia; Malocclusion; Feeding and Eating Disorders of Childhood.


1985 ◽  
Vol 34 (3-4) ◽  
pp. 179-184 ◽  
Author(s):  
K.T.M. Schneider ◽  
K. Vetter ◽  
R. Huch ◽  
A. Huch

AbstractAcute polyhydramnios in the second trimestr is a typical complication in monozygous twin pregnancies. It is caused by a feto-fetal transfusion with anemia on the donor and polycytemia on the recipient twin. Contrary to the chronic hydramnios, there is no increase in malformations. In view of the high mortality rate (100%, according to most authors), the clinical management has to be reconsidered. During the years 1979 to 1983, 10 cases of acute polyhydramnios have been observed at the University Hospital in Zurich. This corresponds to an incidence of 9% in our twin population. All cases investigated were MZ twin pregnancies. With the exception of one patient, who underwent an abortion, all women were hospitalized, had bed rest and received recurrent removals of amniotic fluid and prophylactic tocolysis. The mean gestational age at the time of diagnosis was 23 4/7 weeks and at delivery 30 3/7 weeks. In two cases – one of which is presented in detail – with an unintentional puncture of a placental vessel, the recurrence of the hydramnios did not appear. Eight of 18 newborns survived. No malformations were found. Bed rest, tocolysis and recurrent amniocenteses seem to have a positive influence on the prolongation and outcome of the gestation in acute polyhydramnios.


2015 ◽  
Vol 100 (5) ◽  
pp. 2098-2105 ◽  
Author(s):  
Peter Laurberg ◽  
Dalia C. Berman ◽  
Inge Bülow Pedersen ◽  
Stig Andersen ◽  
Allan Carlé

Abstract Context: Double vision (diplopia) is a major determinant of work disability in patients with Graves' orbitopathy (GO), but is not part of the classification NOSPECS classification of GO. Objective: The objectives of the study were to quantitate diplopia in patients with moderate to severe GO and to study associations with other disease and patient variables. Design: This was a single-center prospective study of consecutive patients at the time of referral. Setting: The study was conducted at the University Hospital Thyroid-Eye Clinic. Patients: Patients included 216 patients diagnosed with moderate to severe and active GO. Main Outcome Measures: Binocular diplopia in field of gaze and monocular fields of motility were prospectively recorded on diagrams and measured by planimetry. Fields of diplopia were correlated to other disease and patient variables. Results: Six patients had only one functional eye and were excluded. Among the remaining 210 patients, diplopia was present in 75.2%. In patients with diplopia, this ranged from 5% to 100% (observed in 11.4% of patients) of binocular field of gaze. The field of diplopia correlated positively with eye motility restriction and with asymmetrical affection of orbits but negatively with signs of inflammation and proptosis that often are the main outcome measures in clinical studies of GO therapy. Conclusion: Diplopia is very common in moderate to severe GO and a major cause for active therapy. In moderate to severe GO, the field of diplopia correlates negatively with some other indicators of disease activity, which may be explained by the physiological properties of binocular fusion.


2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Mbaye Fall ◽  
Doudou Gueye ◽  
Ibrahima Bocar Wellé ◽  
Faty Balla Lo ◽  
Aloise Sagna ◽  
...  

Appendiceal pathology’s management has benefited in recent years from the advent of laparoscopic surgery. This study is to make a preliminary assessment of laparoscopic management of acute and complicated appendicitis in children after a few months of practice at the University Hospital Albert Royer, Dakar. This is a retrospective study of 22 cases of patients, all operated on by the same surgeon. The parameters studied were age, sex, clinical data and laboratory features, radiological data, and results of surgical treatment. The mean age of patients was 9.5 years with a male predominance. The series includes 14 cases of acute appendicitis and 8 complicated cases. Appendectomy anterograde is practiced in 81% of cases. Appendectomy was associated with peritoneal wash in 17 patients including 9 cases of acute appendicitis. Drainage of Douglas pouch is performed in 2 patients with complicated appendicitis; the average production was 300 cc of turbid liquids and any complications were not founded. An abscess of Douglas pouch is noted in 2 patients with complicated appendicitis undrained. These Douglas abscesses were treated medically. No conversion of laparotomy was performed in the series. After an average of 8 months no other problems were noted.


2005 ◽  
Vol 11 (3) ◽  
pp. 470-477
Author(s):  
M. Yahyaoui

Neurosyphilis accounts for 56%-70% of all visceral syphilis and is a complication in 5%-10% of cases of untreated syphilis. The aim of this study was to evaluate the epidemiological aspects and clinical presentations of neurosyphilis in Morocco through a series of 201 patients attending the Centre for Neurological Services at the university hospital in Rabat between 1986 and 1997. The mean age of the patients was 41.26 [SD 9.23] years [range:17-70 years] ; the majority [91%] were male. The incidence of neurosyphilis in Morocco is high. From 31 cases per year in 1985, it has fallen since 1990 to reach 10 cases in 1997. Among the different clinical presentations recorded, chronic meningoencepahalitis was the commonest, followed by meningovasculitis, tabes dorsalis and optic atrophy


2016 ◽  
Vol 15 (4) ◽  
pp. 704
Author(s):  
Flavia do Valle Andrade Medeiros ◽  
Valdecyr Herdy Alves ◽  
Cristina Ortiz Sobrinho Valete ◽  
Eny Dórea Paiva ◽  
Diego Pereira Rodrigues ◽  
...  

Aim:  To  identify  the  type  of  sepsis  which  affected  newborns  withvery  low  birth  weight  and  invasive  care  procedures  to  which  they were  subjected  in  a university hospital in the city of Niterói, between the years 2008 and 2012. Method: This is a retrospective descriptive study using secondary data research in the medical records of  newborns  admitted  to  the  Neonatal  Intensive  Care  Unit  of  the  University  Hospital Antônio Pedro. Results: Of the 49 infants studied, 35 were diagnosed with early sepsis, eight with early and late sepsis and six late. The mean gestational age was 30.5 weeks and  the  weight  1.176,1  kg.  The  most  frequently  performed  care procedures  were: peripheral  venipuncture  (87.8%),  central  catheter  peripheral  venipuncture  (81.6%), assistance  to  ventilation  in  the  delivery  room  (69.4%)  and  intubation  in  the  delivery room  (28.6%).  Conclusion:  It is inferred  that the  lower  birth  weight is  associated  with the higher incidence of sepsis.


2021 ◽  
Vol 12 (1) ◽  
pp. 8-16
Author(s):  
Talita Leite dos Santos Moraes ◽  
Joana Monteiro Fraga de Farias ◽  
Brunielly Santana Rezende ◽  
Fernanda Oliveira de Carvalho ◽  
Michael Silveira Santiago ◽  
...  

Background: Progressive mobility in the ICU has been recommended; however, the definitions of low, moderate, and high mobility in the ICU still diverge between studies. Therefore, our objective was to classify the mobility of the sample from verticalization and active withdrawal from the bed, and from that, to analyze the chances of discharge, death, and readmission to the ICU. Materials and methods: This is an observational and retrospective study that consults the medical records of individuals admitted to the ICU of the University Hospital of Sergipe (HU/SE) between August 2017 and August 2018. Mobility level was classified based on the Intensive Care Unit Mobility Scale (IMS). Results: A total of 121 individuals were included. The mean age was 61.45 ± 16.45, being 53.7% female. Of these, 28 (23.1%) had low mobility, 33 (27.3%) had moderate mobility, and 60 (49.6%) had high mobility. Individuals with low mobility were 45 times more likely to die (OR = 45.3; 95% CI = 3.23–636.3) and 88 times less likely to be discharged from the ICU (OR = 0.22; 95% CI = 0.002–0.30). Conclusion: Those who evolved with low mobility had a higher chance of death and a lower chance of discharge from the ICU. Moderate and high mobility were not associated with the investigated outcomes.


2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Hiroo Imazu ◽  
Shiaw-Hooi Ho ◽  
Shoryoku Hino ◽  
Khean-Lee Goh ◽  
Mitsuhiko Moriyama ◽  
...  

Background. We developed a novel oblique-tip papillotome (OT-papillotome) to facilitate biliary cannulation during endoscopic retrograde cholangiopancreatography (ERCP). This study was performed to evaluate the utility of the OT-papillotome for contrast-guided cannulation (CGC) and wire-guided cannulation (WGC) during ERCP, compared with standard cannulation by WGC using a standard-tip papillotome (ST-papillotome). Methods. A prospective study was performed at two centers. CGC with the OT-papillotome (OT-CGC group) was performed at Jikei University Hospital, while WGC was done with the OT-papillotome and ST-papillotome (OT-WGC and ST-WGC groups, respectively) at the University of Malaya Medical Centre. The results of the OT-CGC and OT-WGC groups were compared with those of the ST-WGC group after performing coarsened exact matching (CEM) to reduce bias due to nonrandomized and center-based patient allocation. Results. Eighty patients were enrolled in each of the OT-CGC, OT-WGC, and ST-WGC groups. After CEM, the successful biliary cannulation rate was significantly higher in the OT-CGC and OT-WGC groups than in the ST-WGC group, while rescue cannulation was reduced. The mean number of unintended pancreatic access events in the OT-WGC and OT-CGC groups was similar to the ST-WGC group. However, it was significantly lower in the OT-WGC group than in the OT-CGC group. Multivariate analysis revealed that the OT-papillotome was independently associated with less frequent rescue cannulation and a higher successful biliary cannulation rate. Conclusions. Although use of the OT-papillotome in biliary cannulation did not reduce unintended pancreatic access events or PEP compared to the ST-papillotome, the OT-papillotome increased the successful biliary cannulation rate, while reducing the frequency of rescue cannulation procedures. Combining the OT-papillotome with WGC might be the best cannulation technique for minimizing unintended pancreatic access.


2020 ◽  
Vol 7 (4) ◽  
pp. e726 ◽  
Author(s):  
Angela Huttner ◽  
Gilles Eperon ◽  
Agustina M. Lascano ◽  
Serge Roth ◽  
Jean-Marc Schwob ◽  
...  

ObjectiveTo determine whether live-attenuated yellow fever vaccine (YFV) was associated with MS relapse, we evaluated the clinical courses of 23 patients in the year before and the year after immunization at the university hospital of Geneva, Switzerland.MethodsThis self-controlled retrospective cohort included adult patients with MS receiving YFV between 2014 and 2018 and defined the year before vaccination, the 3 months thereafter, and the 9 months following as the pre-exposure (PEP), exposure-risk (ERP), and postrisk (PRP) periods, respectively. The primary outcome was the relative incidence of relapse in the ERP vs the PEP. Secondary end points included the presence of new T2-weighted (T2) or T1-weighted gadolinium-positive (T1Gd+) MRI lesions.ResultsOf 23 patients with MS receiving YFV (20 relapsing MS and 3 primary progressive MS), 17 (74%) were women; mean age was 34 years (SD ±10); and 10 of 23 (40%) were treated with disease-modifying therapies (DMTs). Although 9 patients experienced 12 relapses in the PEP, only one experienced a relapse in the ERP; 3 other patients experienced one relapse each in the PRP. None of the 8 patients receiving natalizumab at the time of vaccination experienced relapse thereafter. In the PEP, ERP, and PRP, 18, 2, and 9 patients had new brain and/or spinal cord lesions on T2 or T1Gd + MRI, respectively.ConclusionsIn this cohort, YF vaccination was associated with neither an increase in MS relapse nor emergence of brain and/or spinal lesions. Further studies are warranted to confirm these findings.Classification of evidenceThis study provides Class IV evidence that for persons with MS, YFV may not increase relapse risk.


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