scholarly journals Double Vision Is a Major Manifestation in Moderate to Severe Graves' Orbitopathy, but It Correlates Negatively With Inflammatory Signs and Proptosis

2015 ◽  
Vol 100 (5) ◽  
pp. 2098-2105 ◽  
Author(s):  
Peter Laurberg ◽  
Dalia C. Berman ◽  
Inge Bülow Pedersen ◽  
Stig Andersen ◽  
Allan Carlé
Keyword(s):  
Outcome Measures ◽  
University Hospital ◽  
Double Vision ◽  
Binocular Fusion ◽  
Binocular Field ◽  
Physiological Properties ◽  
Patient Variables ◽  
Graves Orbitopathy ◽  
The University

Abstract Context: Double vision (diplopia) is a major determinant of work disability in patients with Graves' orbitopathy (GO), but is not part of the classification NOSPECS classification of GO. Objective: The objectives of the study were to quantitate diplopia in patients with moderate to severe GO and to study associations with other disease and patient variables. Design: This was a single-center prospective study of consecutive patients at the time of referral. Setting: The study was conducted at the University Hospital Thyroid-Eye Clinic. Patients: Patients included 216 patients diagnosed with moderate to severe and active GO. Main Outcome Measures: Binocular diplopia in field of gaze and monocular fields of motility were prospectively recorded on diagrams and measured by planimetry. Fields of diplopia were correlated to other disease and patient variables. Results: Six patients had only one functional eye and were excluded. Among the remaining 210 patients, diplopia was present in 75.2%. In patients with diplopia, this ranged from 5% to 100% (observed in 11.4% of patients) of binocular field of gaze. The field of diplopia correlated positively with eye motility restriction and with asymmetrical affection of orbits but negatively with signs of inflammation and proptosis that often are the main outcome measures in clinical studies of GO therapy. Conclusion: Diplopia is very common in moderate to severe GO and a major cause for active therapy. In moderate to severe GO, the field of diplopia correlates negatively with some other indicators of disease activity, which may be explained by the physiological properties of binocular fusion.

scholarly journals The University Hospital Zurich Offers a Medical Online Consultation Service for Men With Intimate Health Problems

2015 ◽  
Vol 11 (3) ◽  
pp. 518-524 ◽  
Author(s):  
Sabine Schmidt-Weitmann ◽  
Urs Schulz ◽  
Daniel Max Schmid ◽  
Christiane Brockes
Keyword(s):  
International Classification Of Diseases ◽  
Health Problems ◽  
Medical Advice ◽  
International Classification ◽  
University Hospital ◽  
Health Issue ◽  
Consultation Service ◽  
Online Consultation ◽  
The University

The University Hospital of Zurich offers a text-based, Medical Online Consultation Service to the public since 1999. Users asked health questions anonymously to tele-doctors. This study focused on the characteristics of male enquirers with intimate health problems, the content of their questions, the medical advice given by tele-doctors and the rating of the service to prove the benefit of an online service for medical laymen. This retrospective study included 5.1% of 3,305 enquiries from 2008 to 2010 using the International Classification of Diseases-10 and International Classification of Primary Care codes relevant for intimate and sexual health problems in men. A professional text analysis program (MAXQDA) supported the content analysis, which is based on the procedure of inductive category development described by Mayring. The average age was 40 years, 63.1% enquirers had no comorbidity, in 62.5% it was the first time they consulted a doctor, and 70.2% asked for a specific, single, intimate health issue. In 64.3%, the most important organ of concern was the penis. Overall, 30.4% asked about sexually transmitted diseases. In 74.4% a doctor visit was recommended to clarify the health issue. The rating of the problem solving was very good. The service was mainly used by younger men without comorbidity and no previous contact with a doctor with regard to an intimate health problem. The anonymous setting of the teleconsultation provided men individual, professional medical advice and decision support. Teleconsultation is suggested to empower patients by developing more health literacy.

scholarly journals Risk of MS relapse after yellow fever vaccination

2020 ◽  
Vol 7 (4) ◽  
pp. e726 ◽  
Author(s):  
Angela Huttner ◽  
Gilles Eperon ◽  
Agustina M. Lascano ◽  
Serge Roth ◽  
Jean-Marc Schwob ◽  
...  
Keyword(s):  
Yellow Fever ◽  
Primary Outcome ◽  
University Hospital ◽  
Yellow Fever Vaccine ◽  
Exposure Risk ◽  
Disease Modifying Therapies ◽  
Spinal Lesions ◽  
Yellow Fever Vaccination ◽  
The University

ObjectiveTo determine whether live-attenuated yellow fever vaccine (YFV) was associated with MS relapse, we evaluated the clinical courses of 23 patients in the year before and the year after immunization at the university hospital of Geneva, Switzerland.MethodsThis self-controlled retrospective cohort included adult patients with MS receiving YFV between 2014 and 2018 and defined the year before vaccination, the 3 months thereafter, and the 9 months following as the pre-exposure (PEP), exposure-risk (ERP), and postrisk (PRP) periods, respectively. The primary outcome was the relative incidence of relapse in the ERP vs the PEP. Secondary end points included the presence of new T2-weighted (T2) or T1-weighted gadolinium-positive (T1Gd+) MRI lesions.ResultsOf 23 patients with MS receiving YFV (20 relapsing MS and 3 primary progressive MS), 17 (74%) were women; mean age was 34 years (SD ±10); and 10 of 23 (40%) were treated with disease-modifying therapies (DMTs). Although 9 patients experienced 12 relapses in the PEP, only one experienced a relapse in the ERP; 3 other patients experienced one relapse each in the PRP. None of the 8 patients receiving natalizumab at the time of vaccination experienced relapse thereafter. In the PEP, ERP, and PRP, 18, 2, and 9 patients had new brain and/or spinal cord lesions on T2 or T1Gd + MRI, respectively.ConclusionsIn this cohort, YF vaccination was associated with neither an increase in MS relapse nor emergence of brain and/or spinal lesions. Further studies are warranted to confirm these findings.Classification of evidenceThis study provides Class IV evidence that for persons with MS, YFV may not increase relapse risk.

scholarly journals ICHD-3 is significantly more specific than ICHD-3 beta for diagnosis of migraine with aura and with typical aura

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Carl H. Göbel ◽  
Sarah C. Karstedt ◽  
Thomas F. Münte ◽  
Hartmut Göbel ◽  
Sebastian Wolfrum ◽  
...  
Keyword(s):  
Emergency Room ◽  
Diagnostic Criteria ◽  
Migraine With Aura ◽  
University Hospital ◽  
Headache Disorders ◽  
Ischemic Attack ◽  
Diagnostic Work ◽  
The University ◽  
Work Up

Abstract Background In the emergency room, distinguishing between a migraine with aura and a transient ischemic attack (TIA) is often not straightforward and mistakes can be harmful to both the patient and to society. To account for this difficulty, the third edition of the International Classification of Headache disorders (ICHD-3) changed the diagnostic criteria of migraine with aura. Methods One hundred twenty-eight patients referred to the emergency room at the University Hospital of Lübeck, Germany with a suspected TIA were prospectively interviewed about their symptoms leading to admission shortly after initial presentation. The diagnosis that resulted from applying the ICHD-3 and ICHD-3 beta diagnostic criteria was compared to the diagnosis made independently by the treating physicians performing the usual diagnostic work-up. Results The new ICHD-3 diagnostic criteria for migraine with aura and migraine with typical aura display an excellent specificity (96 and 98% respectively), and are significantly more specific than the previous ICHD-3 beta classification system when it comes to diagnosing a first single attack (probable migraine with aura and probable migraine with typical aura). Conclusions The ICHD-3 is a highly useful tool for the clinical neurologist in order to distinguish between a migraine with aura and a TIA, already at the first point of patient contact, such as in the emergency department or a TIA clinic.

scholarly journals Patient reported outcome measures in septorhinoplasty surgery

2015 ◽  
Vol 97 (1) ◽  
pp. 63-65 ◽  
Author(s):  
TC Biggs ◽  
LR Fraser ◽  
MJ Ward ◽  
VS Sunkaraneni ◽  
PG Harries ◽  
...  
Keyword(s):  
Outcome Measures ◽  
Primary Care Providers ◽  
Patient Reported Outcome Measures ◽  
Patient Reported Outcome ◽  
University Hospital ◽  
Care Providers ◽  
Outcomes Evaluation ◽  
Assess Patient Satisfaction ◽  
Patient Reported ◽  
The University

Introduction Surgical procedures incorporating a cosmetic element such as septorhinoplasty and otoplasty are currently under threat in the National Health Service (NHS) as they are deemed to be procedures of ‘limited clinical benefit’ by many primary care providers. Patient reported outcome measures (PROMs), which assess the quality of care delivered from the patients’ perspective, are becoming increasingly important in documenting the effectiveness of such procedures. Methods The Rhinoplasty Outcomes Evaluation (ROE) questionnaire, a validated PROM tool, was used to assess patient satisfaction in 141 patients undergoing septorhinoplasty surgery over a 90-month period at the University Hospital Southampton NHS Foundation Trust. Results Overall, 100 patients with a mean follow-up period of 36 months completed the study. The mean ROE score was 73.3%. In addition, 75% of patients questioned were happy with the final result of their operation and 83% would undergo the procedure again if required. These benefits occurred irrespective of age, sex and primary versus revision surgery, and were maintained for up to 71 months following surgery. Conclusions This study has shown that patients are generally satisfied with their functional and cosmetic outcomes following septorhinoplasty surgery. These results help support the case for septorhinoplasty surgery to continue being funded as an NHS procedure.

Characterization of Organ Donors to the Liver Transplant in the State of Ceara: Contribution to Capture Liver

2009 ◽  
Vol 4 (1) ◽  
pp. 61
Author(s):  
Simone Da Silveira Magalhães ◽  
Islane Costa Ramos ◽  
Thelma Leite De Araújo
Keyword(s):  
Liver Transplant ◽  
The State ◽  
Waiting List ◽  
Blood Type ◽  
University Hospital ◽  
Young Males ◽  
The University ◽  
Liver Donors

ABSTRACTObjective: to investigate the profile of liver donors in the State of Ceara, establishing a relationship with the criteria of the receptors waiting list. Methods: a retrospective documental research was done in a University Hospital in Fortaleza city. Data on all liver donors listed in the liver transplant report archive in the surgical center of the hospital, from 2007 to 2008, were collected, through a structured form. The data is presented in tables and analyzed according to the literature. This study has been approved by the Research Ethics Committee of the Federal Hospital of the University in Fortaleza (003.02.09). Results: we concluded that there is a very good benefit rate (88%), considering the livers that could be donated. The main cause of death among the donors was cranio-encephalic trauma, in the age group between 21 and 30 years. The majority of cases weighed between 61 and 80 kg. The blood type O was the most commonly found. The priority and classification of clinical seriousness criteria of the probable receptor were considered. Conclusions: the donors’ profile is in accordance with the criteria of the receptors’ waiting list. It should be noted that most of the donors are young males that suffered transit accidents. Descriptors: liver transplantation; tissue donors; health profile. RESUMOObjetivo: investigar o perfil dos doadores de fígado no estado do Ceará, correlacionando-o com os critérios da lista de espera dos receptores. Métodos: pesquisa documental e retrospectiva realizada em um Hospital Universitário em Fortaleza. Os dados foram coletados com base no detalhamento de todos os doadores listados no Relatório do transplante hepático existente no Centro Cirúrgico da Instituição em 2007 e 2008. Para a coleta foi utilizado um formulário estruturado. Os dados foram apresentados em tabelas e analisados com base na literatura.  O projeto de pesquisa foi aprovado pelo Comitê de Ética em Pesquisa do Hospital Universitário (003.02.09), Resultados: Verificou-se que há uma alta taxa de aproveitamento dos fígados disponibilizados para transplantes no Ceará (88%). A principal causa de morte em doadores foi o traumatismo crânio-encefálico, entre adultos, na faixa etária entre 21 a 30 anos, com peso mais frequente entre 61 a 80 kg. Os doadores do tipo sanguíneo O foram os mais presentes. Considerou-se também as priorizações e os critérios de classificação de gravidade clínica do provável receptor. Conclusão: O perfil do doador atende aos critérios da lista de espera dos receptores, mas deve-se atentar para o fato de serem na sua maioria homens, jovens e vítimas de acidentes de trânsito. Descritores: transplante de fígado; doadores de tecidos; perfil de saúde. RESUMENObjetivo: investigar el perfil de los donadores de hígado en el estado de Ceará, correlacionando estos perfiles con los criterios  de la lista de espera de los receptores. Métodos: se realizo una busque da retrospectiva de documentos en un Hospital Universitario en Fortaleza. Los datos fueron coletados basados en lo detallismo de todos donadores registrados en la lista de transplante hepático existente en el Centro Quirúrgico de la institución entre 2007 y 2008. Para el registro fue utilizado un formulario estructurado. Los datos fueron presentados en tablas y analizados con base en la literatura. El estudio fue aprobado por el Comité de Ética del Hosptial de la Universidad Federal en Fortaleza (003.02.09). Resultados: se verificó que hubo una alta tasa de aprovechamiento de los hígados en disponibilidad para transplantes en Ceará (88%). La principal causa de muerte entre los donadores fue traumatismo cráneo encefálico, entre adultos, en el grupo etario entre 21 a 30 años, con un peso promedio de 61 a 80 Kg. Los donadores de tipo sanguíneo O fueron los más frecuentes. Se consideró también las priorizaciones de los criterios de clasificación de gravedad clínica del probable receptor. Conclusión: el perfil del donador cumple los criterios de la lista de espera de los receptores, pero debe tener en cuenta el fato de seren la mayoría hombres, jovens y víctimas de los accidentes de tránsito. Descriptores: transplante de hígado; donadores de tejidos; perfil de salud. 

scholarly journals EGFRAmplification andIDHMutations in Glioblastoma Patients of the Northeast of Morocco

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Nadia Senhaji ◽  
Sara Louati ◽  
Laila Chbani ◽  
Hind El Fatemi ◽  
Nawal Hammas ◽  
...  
Keyword(s):  
University Hospital ◽  
World Health ◽  
World Health Organization Classification ◽  
Histological Criteria ◽  
The Central Nervous System ◽  
Classification Of Tumors ◽  
Health Organization ◽  
Exon 20 ◽  
The University

Glioblastomas are the most frequent and aggressive primary brain tumors which are expressing various evolutions, aggressiveness, and prognosis. Thus, the 2007 World Health Organization classification based solely on the histological criteria is no longer sufficient. It should be complemented by molecular analysis for a true histomolecular classification. The new 2016 WHO classification of tumors of the central nervous system uses molecular parameters in addition to histology to reclassify these tumors and reduce the interobserver variability. The aim of this study is to determine the prevalence ofIDHmutations andEGFRamplifications in the population of the northeast region of Morocco and then to compare the results with other studies.Methods.IDH1codon 132 andIDH2codon 172 were directly sequenced and the amplification of exon 20 ofEGFRgene was investigated by qPCR in 65 glioblastoma tumors diagnosed at the University Hospital of Fez between 2010 and 2014.Results. The R132HIDH1mutation was observed in 8 of 65 tumor samples (12.31%). No mutation ofIDH2was detected.EGFRamplification was identified in 17 cases (26.15%).Conclusion. A systematic search of both histological and molecular markers should be requisite for a good diagnosis and a better management of glioblastomas.

scholarly journals Banco de termos da linguagem especial de enfermagem da clínica cirúrgica de um hospital universitário

2009 ◽  
Vol 3 (2) ◽  
pp. 204 ◽  
Author(s):  
Ellen Martins Norat ◽  
Elizabeth Vasconcelos Trigueiro ◽  
Maria Miriam Lima da Nóbrega ◽  
Telma Ribeiro Garcia
Keyword(s):  
Professional Practice ◽  
Public Hospital ◽  
University Hospital ◽  
Vocabulary Building ◽  
Nursing Team ◽  
Definition Of ◽  
The University ◽  
Taxonomic Tree ◽  
Surgical Clinic

ABSTRACTObjective: to build up a databank of technical words used in the surgical clinic unit of a public hospital. Method: a survey of the type exploratory-descriptive was conducted by following some methodological vocabulary-building strategies, such as: identification and evaluation of the terminological work; definition of the thematic range of the terminological analysis; construction of a databank domain tree; classification of the theoretical definition of existing terms and the ones that were not found in the ICNP® Version 1.0; and terms validation according to their respective denotations. Results: the 370 terms identified as in use by the University Hospital Surgical Clinic were mapped against the words adopted by the ICNP®, and the result was that 187 terms were found among those employed by the ICNP®, and the remaining 183 were not. These terms were then inserted on to the ICNP® taxonomic tree and duly validated according to their respective definitions by the research team. Conclusion: It has been concluded that the main objective of the present work was achieved with the creation of the Databank of Special Nursing Terms for the Surgical Clinic. One expects that the use of this databank may help the nursing team of the University Hospital to make proper use of their own vocabulary in their daily professional practice. Descriptors: nursing; terminology; vocabulary; surgical nursing.RESUMOObjetivo: construir o Banco de Termos da Linguagem Especial de Enfermagem da unidade de clínica cirúrgica de um hospital público. Método: pesquisa do tipo exploratório-descritiva utilizando-se as etapas da metodologia do trabalho terminológico, tais como: identificação e avaliação da documentação especializada, delimitação do campo temático da análise terminológica, estabelecimento da árvore de domínio das bases de dados; elaboração de definições teóricas para os termos constantes e não constantes na CIPE® Versão 1.0; validação dos termos com suas respectivas definições. Resultados: os 370 termos identificados na Clínica Cirúrgica foram mapeados com os termos da CIPE® resultando em 187 termos constantes e 183 termos não constantes nesta classificação, os quais foram inseridos na árvore taxonômica da CIPE® e validados com suas respectivas definições pelos participantes da pesquisa. Conclusão: Conclui-se que o objetivo do estudo foi alcançado com a construção do Banco de Termos da Linguagem Especial de Enfermagem da Clínica Cirúrgica e espera-se que a sua utilização contribuam para que a equipe de enfermagem do Hospital Universitário utilize seu próprio vocabulário na prática profissional. Descritores: enfermagem; terminologia; vocabulário; enfermagem cirúrgica.RESUMENObjetivo: Construir el Banco de Términos del Lenguaje Especial de Enfermería de la unidad de clínica quirúrgica de un hospital público. Método: La Investigación del tipo exploratorio descriptiva desarrollada utilizándose las etapas de la metodología del trabajo terminológico, saber: identificación y evaluación de la documentación especializada, delimitación del campo temático del análisis terminológico, establecimiento del árbol de dominio de las bases de datos; elaboración de definiciones teóricas para los términos constantes y no constantes en la CIPE® Versión 1.0; validación de los términos con sus respectivas definiciones. Resultados: Los 370 términos identificados en la Clínica Quirúrgica fueron denominados con los términos de la CIPE® resultando en 187 términos constantes y 183 no constantes en dicha clasificación, los cuales fueron insertados en el árbol taxonómico de la CIPE® y validados con sus respectivas definiciones por los participantes de la investigación. Conclusión: Se concluye que el objetivo del estudio fue alcanzado con la construcción del Banco de Términos del Lenguaje Especial de Enfermería de la Clínica Quirúrgica y se espera que su utilización contribuya para que el equipo de enfermería del Hospital Universitario utilice su propio vocabulario en la práctica profesional. Descriptores: Enfermería; terminologia; vocabulário; enfermería quirúrgica.

scholarly journals DETECÇÃO DE REGIÕES SUSPEITAS DE LESÃO NA MAMA EM IMAGENS TÉRMICAS UTILIZANDO SPATIOGRAM E REDES NEURAIS

2013 ◽  
Vol 20 (2) ◽  
pp. 56 ◽  
Author(s):  
Paulo Sérgior Aguiar Junior ◽  
Caio Nogueira Silva Belfort ◽  
Aristófanes Corrêa Silva ◽  
Pedro Henrique Bandeira Diniz ◽  
Rita de Cassia Fernandes de Lima ◽  
...  
Keyword(s):  
Infrared Camera ◽  
Radial Symmetry ◽  
University Hospital ◽  
B Spline ◽  
Higher Temperature ◽  
Left And Right ◽  
The Mean ◽  
Classification Of Regions ◽  
The University

Este trabalho propõe uma metodologia para identificar regiões suspeitas de lesão baseada nas assime-trias da mama esquerda e direita de imagens de termogramas. O estudo é pautado em imagens de pacientes do Hospital Universitário da Universidade Federal de Pernambuco (UFPE), capturadas por câmera infravermelha. Inicialmente as imagens são manualmente segmentadas. Em seguida, os seios são registrados usando a transformação B-spline. Além disso, como o corpo humano tem uma simetria radial das temperaturas, uma lesão, eventualmente, leva uma assimetria destas regiões, em seguida, o spatiogram é usado para identificar essas regiões assimétricas. Finalmente, apenas as regiões com temperaturas superiores à média são mantidas, com base no fato de que o câncer tem a temperatura mais elevada do que o restante mama. Após esse processo são extraídas características (Variação dos pixels, a média, o desvio padrão, o índice de Geary e Dimensão Fractal de Higuchi) para a classificação dessas regiões restantes em lesão ou não lesão utilizando-se uma rede neural artificial com perceptron em multicamadas. A metodologia apresentou 75% das regiões classificadas corretamente, indicando que o spatiogram e a média das temperaturas das regiões assimétricas são métodos bem promissores para identificação de regiões suspeitas de conter lesão.Palavras-chave: Termografia. Câncer. Spatiogram. Mama. Rede-neural.SUSPECT DETECTION OF REGIONS OF INJURY IN BREAST IN THERMAL IM-AGES USING SPATIOGRAM AND NEURAL NETWORKSAbstract: This paper proposes a methodology to identify suspicious regions of injury based on asymmetries of left and right breasts of thermograms images.. The study is based on images captured by infrared camera from patients at the University Hospital of the Federal University of Pernambuco. Initially the images are manually segmented. Then, the sinuses are recorded using the B-spline transformation. Furthermore, as the human body has a radial symmetry of temperatures, damage eventually leads asymmetry of these regions, then the spatiogram is used to identify those asymmetric.regions. Finally, only the regions with higher than average temperatures are maintained, based on the fact that the cancer has a higher temperature than the rest of the breast. After this process features are extracted (Variation of pixels, the mean, standard deviation, index Geary and Higuchi Fractal Dimension) for the classification of regions remaining in injury or no injury using an artificial neural network Multilayer perceptron. The methodology showed 75% of correctly classified regions, indicating that the spatiogram and the average temperatures of the asymmetric regions are well promises methods to identify regions suspected of containing lesion.Keywords: Thermography. Cancer. Spatiogram. Breast. Neural-network.DETECCIÓN DE ZONAS SOSPECHOSAS DE LESIÓN EN LA MAMA EN IMÁGENES TÉRMICAS UTILIZANDO SPATIOGRAM Y REDES NEURALESResumen: En este trabajo se propone una metodología para identificar las regiones sospechosas de lesión basado en las asimetrías de la mama izquierda y derecha de las imágenes termogramas. El estudio se basa en las imágenes capturadas por la cámara infrarroja de los pacientes en el Hospital Universitario de la Universidade Federal de Pernambuco. Inicialmente, las imágenes son segmentadas manualmente. Luego, los senos se registran utilizando la transformación B-spline. Además, como el cuerpo humano tiene  una simetría radial de temperaturas, daños eventualmente conducen a una asimetría de estas regiones, entonces el spatiogram se utiliza para identificar las regiones asimétricas. Finalmente, basado en el hecho de  que el cáncer tiene una temperatura más alta que el resto de la mama, sólo las regiones con temperaturas más alta que la temperatura media son mantenidas. Después de este proceso se extraen características (Variación de píxeles, la media, desviación estándar, Dimensión índice y Higuchi Geary fractal) para la clasificación de las regiones restantes en lesiones o ninguna lesión utilizando un perceptrón multicapa red neural artificial. La metodología mostró 75% regiones clasificados correctamente, lo que indica que las temperaturas spatiogram y media de las regiones son métodos asimétricos bien promete para identificar regiones sospechosas de contener lesión.Palabras clave: Termografía. Cáncer. Spatiogram. Mama. Redes neuronales.

Symptomatic vascular complications after vascular closure device use following diagnostic and interventional catheterisation

VASA ◽  
2004 ◽  
Vol 33 (2) ◽  
pp. 78-81 ◽  
Author(s):  
Thalhammer ◽  
Aschwanden ◽  
Jeanneret ◽  
Labs ◽  
Jäger
Keyword(s):  
Current Literature ◽  
Vascular Complications ◽  
University Hospital ◽  
Closure Device ◽  
Ultrasound Guided ◽  
Vascular Closure Device ◽  
Device Use ◽  
Arterial Stenoses ◽  
The University ◽  
Stenotic Lesions

Background: Haemostatic puncture closure devices for rapid and effective hemostasis after arterial catheterisation are a comfortable alternative to manual compression. Implanting a collagen plug against the vessel wall may become responsible for other kind of vascular injuries i.e. thrombotic or stenotic lesions and peripheral embolisation. The aim of this paper is to report our clinically relevant vascular complications after Angio-Seal® and to discuss the results in the light of the current literature. Patients and methods: We report the symptomatic vascular complications in 17 of 7376 patients undergoing diagnostic or therapeutic catheterisation between May 2000 and March 2003 at the University Hospital Basel. Results: Most patients presented with ischaemic symptoms, arterial stenoses or occlusions and thrombotic lesions (n = 14), whereas pseudoaneurysms were extremely rare (n = 3). Most patients with ischaemic lesions underwent vascular surgery and all patients with a pseudoaneurysm were successfully treated by ultrasound-guided compression. Conclusions: Severe vascular complications after Angio-Seal® are rare, consistent with the current literature. There may be a shift from pseudoaneurysms to ischaemic lesions.

Sign in / Sign up

Export Citation Format

Share Document