COMPARATIVE ANALYSIS OF RDW VARIABILITY DEPENDING ON BELONGING TO A DEFINED NOSOLOGICAL GROUP OF DISEASES ACCORDING TO ICD-10 CLASSIFICATION

2020 ◽  
Vol 65 (8) ◽  
pp. 487-491
Author(s):  
O. V. Gaisenok
Keyword(s):  
Comparative Analysis ◽  
Blood Test ◽  
Blood Count ◽  
Reference Range ◽  
Complete Blood Count ◽  
Final Analysis ◽  
Blood Diseases ◽  
Rank Analysis ◽  
Icd 10 ◽  
Disease Analysis

The aim of this study was to investigate RDW variability and conduct a comparative analysis of the RDW level in patients depending on their belonging to a defined nosological group of diseases according to the ICD-10 classification. All patients who complete blood count tests in our hospital from January to December 2016 were included in the study. The identification of the patient’s belonging to a specific nosological group according to the ICD-10 classification was carried out on the basis of the disease analysis code indicated in the direction of the blood test. 8056 patient records were included in the final analysis. Deviations beyond the upper reference range for the RDW indicator (> 14.5%) in this study were identified for patients of the following nosological groups according to ICD-10: C - neoplasms; D - blood diseases; S - injuries; T - poisoning. Significant intergroup differences were obtained according to the Kruskal-Wallis rank analysis of variance (Kruskal-Wallis test: H (19, n= 7622) = 214.9672 p = 0.0000). According to the results of this study, we can conclude that RDW has specificity for certain diseases (neoplasms; blood diseases; injuries; poisoning). In case of cardiovascular and other diseases, deviations of this indicator beyond the limits of the upper reference values were not found in this study.

scholarly journals Blood nickel level and its toxic effect after transcatheter closure of persistent duct arteriosus using Amplatzer duct occluder

2009 ◽  
Vol 49 (1) ◽  
pp. 33
Author(s):  
Mulyadi M. Djer ◽  
Bambang Madiyono
Keyword(s):  
Time Series ◽  
Renal Function ◽  
Blood Glucose ◽  
Time Series Analysis ◽  
Blood Test ◽  
Blood Count ◽  
Complete Blood Count ◽  
Transcatheter Closure ◽  
Toxic Effects ◽  
Amplatzer Duct Occluder

Background  Transcatheter closure using amplatzer  duct  occluder(ADO)  is  currently the  treatment  of  choice for  patent  ductusarteriosus (PDA).  The  ADO  device  is  constructed from a Nitinolwire mesh containing 55% nickel. Up  to  now, there  is  still acontroversy about the effects  of  nickel contained in ADO.Objectives  To  determine blood nickel level  at  six months aftertranscatheter closure  of  PDA  using  ADO,  toxic effects  of  nickelat six months after  PDA  closure using  ADO,  and the effects  ofnickel  on  complete blood  count  (CBC), blood glucose and renalfunction.Methods  Subjects  were  patients  with  PDA  at  IntegratedCardiovascular Services,  Dr.  Cipto Mangunkusumo Hospital,Jakarta. Routine blood test and blood nickel levels were measuredat  the time  of  the procedure,  and  at  the  end  of  the first, third,  andsixth months after intervention.Results  There  were  29  patients who underwent heart catheteri-zation  and  PDA closure using  ADO.  A time series analysis wasconducted  on  23  patients who completed six-month follow-upafter the intervention. Median blood nickel level before procedurewas 58 ng/mL while  at  one, three  and  six months afterwards were60, 63 and 64 ng/mL respectively.  The  blood nickel levels didnot  differ significantly between pre- and  post-ADO. After  PDAclosure,  no  toxic effects  of  nickel were found,  both  clinically andlaboratorically.Conclusions  PDA  closure using  ADO  has no effects  on  the nickellevels, CBC, blood glucose and renal function;

scholarly journals A Simple Blood Test, Such as Complete Blood Count, Can Predict Calcification Grade of Abdominal Aortic Aneurysm

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Marika Vezzoli ◽  
Stefano Bonardelli ◽  
Michele Peroni ◽  
Marco Ravanelli ◽  
Emirena Garrafa
Keyword(s):  
Risk Factors ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Blood Test ◽  
Blood Count ◽  
Complete Blood Count ◽  
Strong Association ◽  
The Other ◽  
Rapid Imaging ◽  
Abdominal Aortic

Objective. The pathogenesis of abdominal aortic aneurysm (AAA) is complex and different factors, including calcification, are linked to increased complications. This study was conducted in order to verify if classical risk factors for AAA and cell blood count parameter could help in the identification of calcification progression of the aneurysm. Design. Risk factors were collected and cell blood count was performed in patients with AAA and patients were analyzed for the presence of aorta calcification using CT angiography. Results. We found no association of calcification grade with risk factors for AAA but we found a strong association between MCV, MCH, and calcification grade. Instead, no association was found with the other parameter that we analyzed. Conclusions. In this study, we demonstrate that biomarkers such as MCV and MCH could have potential important information about AAA calcification progression and could be useful to discriminate between those patients that should undergo a rapid imaging, thus allowing prompt initiation of treatment of suspicious patients that do not need imaging repetition.

scholarly journals Isolated Neutropenia/Benign Ethnic Neutropenia: A Common Clinical and Laboratory Finding in Southern and Southwestern Saudi Arabia

2020 ◽  
Author(s):  
Zuhier A. Awan ◽  
Saeed M. Al Amoudi ◽  
Muhammad Saboor ◽  
Husain Y. Alkhaldy
Keyword(s):  
Saudi Arabia ◽  
Blood Count ◽  
Complete Blood Count ◽  
Laboratory Finding ◽  
Fasting Blood Glucose ◽  
Final Analysis ◽  
Thyroid Function Test ◽  
Cross Sectional ◽  
High Prevalence ◽  
Study Laboratory

Objectives: Isolated mild neutropenia is a common clinical problem. The current study aims to validate our previous findings regarding the high prevalence of isolated neutropenia in Southern and Southwestern Saudi Arabia and explore the effect of altitude or regional differences. Methods: In this retrospective cross-sectional study, laboratory results of a commercial laboratory were screened over a period of 5 years (2016–2020) in seven different cities in South and southwestern Saudi Arabia. Participants’ laboratory investigations were reviewed and excluded for any ab-normal complete blood count, renal profile, liver profile, lipid profile, thyroid function test, fasting blood glucose, or HbA1c findings. Descriptive analysis and 95th percentile range were calculated using standard statistical methods. Results: A total of 91,880 complete blood count results were included in the final analysis. isolated neutropenia is common laboratory finding, with a prevalence ranging from 11-23%. The 2.5th percentile of the neutrophil count was lower than 1.5×109/L in all seven cities. Conclusions: Mild to moderate neutropenia is common in Southern and Southwestern Saudi Arabia. Benign ethnic neutropenia (BEN) may explain this high prevalence. Since BEN has no clinical significance, the reference range for normal neutrophil counts needs to be adjusted to reflect the effect of BEN.

scholarly journals Reference Range of Complete Blood Count in Healthy Term Newborns 1 Week after Birth

2021 ◽  
Vol 9 (A) ◽  
pp. 1565-1569
Author(s):  
Harapan Parlindungan Ringoringo
Keyword(s):  
Birth Weight ◽  
Standard Deviation ◽  
Blood Count ◽  
Reference Range ◽  
Complete Blood Count ◽  
White Blood Count ◽  
Inclusion Criteria ◽  
Term Newborns ◽  
Prospective Analyses

BACKGROUND: Determination of the complete blood count (CBC) and reticulocyte reference range helps diagnose a disease related to changes in erythrocyte indices, white blood count, platelets, and reticulocytes, especially in newborns. AIM: The aim study is to establish a reference range for CBC and reticulocyte in healthy term newborns 1 week after birth. MATERIAL AND METHODS: The study method is prospective analyses of CBC and reticulocyte in term newborns within 1 week after birth. Inclusion criteria are term newborn (gestational age 37–42 weeks) with good tone, breathing, or crying immediately, do not have resuscitation, and the birth weight is ≥2500 g. RESULTS: Two hundred and seventy-seven term newborns met the inclusion criteria. There were 145 (52.35%) male infants and 132 (47.65%) female infants. The reference range of newborns for hemoglobin (Hb) at P2.5–P97.5, P3–P97, P5–P95, and mean ± 2 standard deviation (SD) was 11.70–19.60 g/dL, 11.90–19.57 g/dL, 12.20–19.20 g/dL, and 11.35–19.63 g/dL, respectively. In addition, reference range of male newborns for Hb at P2.5–P97.5, P3–P97, P5–P95, and mean ± 2SD was 12.20–20.14 g/dL, 12.28–19.91 g/dL, 12.63–19.38 g/dL, and 11.47–20.15 g/dL, respectively. The reference range of female newborns for Hb at P2.5–P97.5, P3–P97, P5–P95, and mean ± 2 SD was 11.37–19.20 g/dL, 11.50–19.20 g/dL, 11.80–19.20 g/dL, and 11.37–18.93 g/dL, respectively. CONCLUSION: The reference range of CBC and reticulocyte for healthy term newborns, male newborns, and female newborns in this study can be used as a benchmark.

Comparative Analysis of Red Blood Cells Distribution Width and c-Reactive Protein Levels Depending on the Presence of Probable Familial Heterozygous Hypercholesterolemia: Findings from Laboratory Registry Data

2018 ◽  
Author(s):  
Oleg V. Gaisenok ◽  
Nina I. Razlivaeva
Keyword(s):  
Comparative Analysis ◽  
Complete Blood Count ◽  
Low Density Lipoprotein ◽  
Circulatory System ◽  
Density Lipoprotein ◽  
Final Analysis ◽  
Study Group ◽  
Distribution Width ◽  
Protein Levels ◽  
Circulatory System Diseases

The aim of this study was to identify patients with probable family heterozygous hypercholesterolemia (PFH) and carry out a comparative analysis of RDW and CRP levels depending on the presence of PFH. All patients who underwent complete blood count, total cholesterol (TC) and low-density lipoprotein cholesterol (LDL) tests in our hospital from January to December 2016 were included in the study. CRP data for each patient were added to the database, if available. 8056 patient records were included in the final analysis. Simon Broome Register criteria (TC>7.5mmol/l or/and LDL>4.9mmol/l) were used as diagnostic criteria for PFH in this study. The detectability of PFH significantly exceeded the expected average population statistical indices. Detectability of PFH by TC criterion was 5.9% for the whole study group and 5.3% for circulatory system diseases (CSD) patients; and even higher by LDL criterion for the whole study group - 8.0%, for CSD patients - 7.5%. Statistically significant differences in RDW level were obtained only for LDL criterion in CSD patients (but not for the whole study group). Among them, RDW level was lower in PFH patients: 12.9+0.8 (n = 173) vs 13.2+0.8 (n=2119), p=0.007. There were no differences in the CRP level in all subgroups.

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