scholarly journals COMPARISON OF DIAGNOSTIC METHODS AND TREATMENT OF ENDOMETRIOSIS OF ATYPICAL LOCATION

2018 ◽  
Vol 5 (3) ◽  
pp. 157-163
Author(s):  
D. D Shlyk ◽  
Yury E. Kitsenko ◽  
D. R Markaryan ◽  
V. I Lanchinskiy ◽  
I. A Tulina ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Abdominal Cavity ◽  
Malignant Neoplasm ◽  
Early Postoperative Period ◽  
Diagnostic Methods ◽  
Reproductive Age ◽  
Treatment Technique ◽  
Intravenous Contrast ◽  
Preoperative Stage ◽  
Extragenital Endometriosis

Surgical treatment and subsequent management of women of reproductive age with endometriosis of extragenital localization involving intestine, whose frequency is up to 37%, currently do not have a detailed and clearly described protocol, which may be caused by the complexity of diagnosis at the preoperative stage. In most cases, extragenital localization is an intraoperative finding. The purpose of the article is to evaluate the complexity of diagnosing the atypical location of extragenital endometriosis, systematize the diagnostic protocol and present the chosen treatment tactics. Material and methods. In the clinic of coloproctology and minimally invasive surgery, 4 observations of extragenital endometriosis with intestinal lesions were noted. According to the results of diagnostic studies (multispiral computed tomography - MSCT of the abdominal cavity with intravenous contrast, irrigoscopy with double contrasting, colonoscopy with biopsy), endometriosis was confirmed in 2 patients at the preoperative stage. All patients underwent surgical interventions in the volume of resection of the affected segment of the intestine within the unchanged tissues. Results. According to the intraoperative revision, in all patients there was noted the presence of additional extragenital foci of different localization, which were destroyed by diathermocoagulation. Patients with unverified endometriosis also underwent lymphadenectomy in D2 volume due to the inability to exclude malignant neoplasm. In the early postoperative period, no complications were noted. Only 1 patient decided to take hormonal therapy for 6 months after the operation. At present, none of the relapses have been observed, the mean follow-up time is 17.3 ± 13.6 months (4-33 months). In all patients there was recovered the menstrual cycle, menstruation moderately painful, previous abdominal pains before menstruation and spotting discharges from the rectum stopped. Conclusion. Surgical treatment of extragenital endometriosis of intestinal localization in the volume of resection of the affected intestine within the unchanged tissues is the optimal treatment technique and is not accompanied by significant complications. However, in cases of unverified histologically endometriosis, principles of oncological radicalism should be kept. To select the optimal volume of surgical intervention and access, a multidisciplinary consultation with the coloproctologist, gynecologist and with the obligatory consideration of the patient’s opinion is required.

scholarly journals The first experience of partial spleen embolization for the correction of thrombocytopenia in patients with liver cirrhosis

2021 ◽  
Vol 26 (3) ◽  
pp. 97-103
Author(s):  
A. V. Shabunin ◽  
V. V. Bedin ◽  
P. A. Drozdov ◽  
O. N. Levina ◽  
V. A. Tsurkan ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Liver Cirrhosis ◽  
Postoperative Period ◽  
Primary Liver Cancer ◽  
Abdominal Cavity ◽  
Early Postoperative Period ◽  
Computed Tomography Scan ◽  
Intravenous Contrast ◽  
Viral Hepatitis C ◽  
Tomography Scan

Aim. To assess the efficacy and safety of interventional endovascular partial spleen embolization for the correction of thrombocytopenia in patients with liver cirrhosis.Material and methods. From September 2019 to March 2020, 5 partial spleen embolizations were performed at the surgical clinic of the Botkin Hospital. The indication was the impossibility of conducting courses of regional chemotherapy for primary liver cancer in 2 patients with cirrhosis, portal hypertension, hypersplenism, thrombocytopenia, in 3 patients – the impossibility of conducting adequate antiviral therapy with cirrhosis as a result of chronic viral hepatitis C. The platelet count was < 25 thousand/μl (19.34 ± 1.34 thousand/μl) in all patients at the time of the procedure. The median spleen volume was 1967.54 ± 476.13 (1324.34–2163.54) cm3 . We used Progreat® Terumo 2.8 Fr microcatheter 130 cm for catheterization branches of the splenic artery. Endovascular embolization was performed with microspheres 600 ± 75 nm – 2 ml before occlusion. Computed tomography scan of abdominal cavity with intravenous contrast enhancement and laboratory test of platelet levels were performed. Follow up of patients was carried out at 1, 3 and 6 months after this intervention.Results. The postoperative period in all patients was uncomplicated. Postembolization syndrome (pain, hyperthermia) developed in the early postoperative period in all patients on the next day after the procedure. Computed tomography scan of the abdominal cavity revealed areas of an irregular shape of low density that did not accumulate a contrast agent. The duration of hospitalization was 7.63 ± 3.32 (5–11) days. There were not in-hospital and 30-day mortality in our study.Conclusion. The first experience of endovascular partial spleen embolization showed its safety and efficacy in the correction of thrombocytopenia in patients with liver cirrhosis.

scholarly journals Laparoscopic dissection in children with celiac artery compression syndrome

2021 ◽  
Vol 11 (2) ◽  
pp. 131-140
Author(s):  
Razhab A. Zainulabidov ◽  
Alexander Y. Razumovsky ◽  
Zorikto B. Mitupov ◽  
Galina Y. Chumakova
Keyword(s):  
Abdominal Pain ◽  
Surgical Treatment ◽  
Clinical Symptoms ◽  
Abdominal Cavity ◽  
Treatment Success ◽  
Celiac Trunk ◽  
Early Postoperative Period ◽  
Median Arcuate Ligament ◽  
Flow Measurements ◽  
Arcuate Ligament

BACKGROUND: A cause of abdominal pain in children may be compression stenosis of the celiac trunk (Dunbars syndrome). This disease occurs when the median arcuate ligament of the diaphragm compresses the celiac trunk, thereby creating compression stenosis, causing the arterial hemodynamics in the artery to suffer and provide adequate blood circulation to the abdominal cavity organs. Medical statistics indicate that 10% to 15% of children and adolescents suffering from chronic abdominal pain have compression stenosis of the celiac trunk. AIM: This study aims to improve the diagnostic results and identify the indications for the surgical treatment of children with compression stenosis of the celiac trunk. MATERIALS AND METHODS: From 2015 to 2020 at the N.F. Filatov Childrens Hospital, 64 patients, aged 4 to 17 years underwent surgical treatment for compression stenosis of the celiac trunk. There are 42 boys (66%) and 22 girls (34%). The leading clinical manifestation in all patients was abdominal pain. Associated surgical pathology was observed in 34 of them. The diagnosis was based on anamnesis, examination, ultrasound examination with Doppler and celiac trunk blood flow measurements, multispiral computed tomography, and angiography. RESULTS: After completing the examination, 61 patients underwent laparoscopic decompression of the celiac trunk, and three children were operated on using the laparotomic approach. In all cases, the leading cause of compression stenosis of the celiac trunk was the median arcuate ligament of the diaphragm combined with the neurofibrous tissue of the celiac plexus. The average duration of the operation was 50 minutes. Intraoperative blood loss did not exceed 530 ml. One conversion completed. There were no postoperative complications in the early postoperative period. The patients were discharged in satisfactory condition. The control examination was conducted in the period from six months to three years. In 97% of patients, clinical symptoms of abdominal ischemia were not detected. CONCLUSION: Our experience indicates the possibility of diagnosing compression stenosis of the celiac trunk in children at early disease stages and laparoscopic treatment success of patients with this disease.

scholarly journals STRUCTURAL ANALYSIS OF CLINICAL AND LABORATORY AND INSTRUMENTAL DIAGNOSIS AND TREATMENT OF ACUTE PANCREATITIS

2021 ◽  
pp. 52-58
Author(s):  
M. I. Pokidko ◽  
T. V. Formanchuk ◽  
A. G. Sychevska ◽  
O. B. Tkachenko
Keyword(s):  
Acute Pancreatitis ◽  
Surgical Treatment ◽  
Severe Acute Pancreatitis ◽  
Abdominal Cavity ◽  
Early Period ◽  
Total Mortality ◽  
Infusion Therapy ◽  
Intravenous Contrast ◽  
Postoperative Pancreatitis ◽  
Overall Mortality

Summary. The purpose of the study: to analyze the causes of development, terms of hospitalization, the frequency of severe type, complications and overall mortality in acute pancreatitis according to the clinic data. Materials and methods: the results of treatment of 622 patients with acute pancreatitis were analyzed. Among them there were 336 women (54.1 %) and 286 men (45.9 %). The mean age of patients was (48.2 ± 2.2) years. The diagnosis of acute pancreatitis was made according to the recommendations (Atlanta, 2012). All patients with acute pancreatitis underwent ultrasound examination of the abdominal cavity and computed tomography, enhanced by intravenous contrast. Results and discussion: Etiological factors of acute pancreatitis were: biliary factor in 270 (43.4 %) patients, alcohol — in 155 (24.9 %), acute pancreatitis on the background of triglyceridemia — in 135 patients (21.7 %), 21 (3.4 %) patients had postoperative pancreatitis, medication — in 8 (1.3 %) patients and without a clear etiology — in 33 (5.3 %) patients. The terms of hospitalization of patients are as follows: after 24–48 hours from the onset of the disease — 215 (34.6 %) cases, after 6–24 hours after the onset of the disease — 204 (32.8 %) cases, after 48 hours and later from the time of the disease — 129 (20.7 %) cases and 74 (11.9 %) cases of hospitalization up to 6 hours from the onset of the disease. Severe acute pancreatitis developed in 147 (23.6 %) patients and was accompanied by the development of organ failure lasting > 48 hours. 594 (95.4 %) patients with acute pancreatitis received only conservative infusion therapy. 28 (4.5 %) patients required surgical treatment. The overall mortality in patients with acute pancreatitis was 9 (1.4 %) cases. Conclusions: Hyperdiagnosis of acute pancreatitis is a common problem in modern surgery. Formulation of the diagnosis according to the unified diagnostic criteria considerably facilitated diagnosis. The dominant factors of acute pancreatitis are biliary (43.4 %) and alcoholic factors (24.9 %). Most often (34.6 %) patients were admitted to the department on the second day after the onset of the disease. Remains high level of severe acute pancreatitis, which amounted to 23.6 % of cases. 594 (95.4 %) patients with acute pancreatitis received infusion therapy. 28 (4.5 %) patients underwent surgical treatment. The total mortality in acute pancreatitis according to our clinic was 9 (1.4 %) cases, the majority of them (7 patients) died in the early period of acute pancreatitis.

scholarly journals Polypropylene endoprostheses in the surgical treatment of strangulated postoperative ventral hernias

2012 ◽  
Vol 93 (3) ◽  
pp. 541-544
Author(s):  
I M Fatkhutdinov
Keyword(s):  
Surgical Treatment ◽  
Abdominal Wall ◽  
Abdominal Wall Defect ◽  
Subcutaneous Tissue ◽  
Abdominal Cavity ◽  
Subcutaneous Fat ◽  
Postoperative Mortality ◽  
Early Postoperative Period ◽  
Mesh Endoprostheses ◽  
Ventral Hernias

Aim. To determine and implement the best ways to position mesh endoprostheses in the anterior abdominal wall during strangulated postoperative ventral hernias; to introduce methods of non-stretch hernioplasty into emergency surgery of giant hernias. Methods. 115 patients (27 males and 88 females) with strangulated postoperative ventral hernias aged 30-73 years were under observation. Depending on the size of the hernia and on the intraoperative findings different methods of implantation of the mesh endoprostheses were used, which prevented the mesh contact with subcutaneous fat and abdominal organs. For small and medium-sized hernias the mesh was placed under or over the abdominal membrane, it was fixed to the abdominal wall, the aponeurosis was sewn together in an «edge to edge» fashion. In cases with giant hernias non-stretch hernioplasty was performed. During the operation of non-stretch hernioplasty, dissection and excision of the hernial sac was performed in such a way that made it possible to use it to cover the abdominal wall defect. Results. In the early postoperative period in 17 (14.8%) patients seromas had formed in the wound, which were treated by needle puncture under ultrasound guidance. Postoperative mortality was 5.2% (6 people). In 5 cases the deaths were due to myocardial infarction and pulmonary embolism. One patient developed peritonitis due to suture insufficiency of the enteric anastomosis. Of all patients with lethal outcomes five patients were admitted after more than 6 hours from the start of the strangulation, one patient was admitted after 3 hours. Conclusion. The usage of techniques that delimit the mesh prosthesis from the abdominal cavity and subcutaneous tissue, and the introduction of non-stretch methods for giant hernias in the surgical treatment of strangulated postoperative ventral hernia contribute to improved outcomes of treatment in this group of patients.

scholarly journals Bile leak syndrome after laparoscopic cholecystectomy

2019 ◽  
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Surgical Treatment ◽  
Bile Duct ◽  
Common Bile Duct ◽  
Minimally Invasive ◽  
Abdominal Cavity ◽  
Bile Leak ◽  
Bile Leakage ◽  
Early Postoperative Period ◽  
Type I

Aim of the study was the assasement of surgical treatment results of patients with cholelithiasis, who had external or internal bile leakage (BL), for the optimization and improvement of diagnostic programme and surgical tactic of minimally invasive techniques usage. Materials and methods. Results of surgical treatment during the early postoperative period of patients with cholelithiasis, who underwent laparoscopic cholecystectomy (LC) were analysed. Results. In early post-operative period 67 (0,6%) patients, mean aged 56,9 ± 7,4 had BL. 54 (81,0%) of them were women, 13 (19,0%) were men. 21 (31,3%) patients underwent LC due to chronic cholecystitis, 46 (68,7%) patients had acute cholecystitis. In 54 (81,0%) cases there was drainage bile leakage, in 13 (19,0%) cases bile collection in abdominal cavity was identified several days after drains ejection, due to clinical manifestation and ultrasonography data. 23 (34,3%) patients were treated conservatively. Minimally invasive endoscopic manipulations, ultrasonography controlled percutaneous drainage and relaparotomy were effective in 35 (52,2%) patients, 9 (13,4%) patients underwent laparotomy with following surgical correction of BL. These patients had dense perivesical infiltrates, Mirizzi’s syndrome type I. 6 (9,0%) patients underwent laparotomy, abdominal cavity sanation and drainage. In 1 (1,5%) case partial right bile duct injury was identified, defect suturing and Vishnevsky common bile duct drainage. In 2 (3,0%) cases the cause of BL was more than 2/3 diameter injury of common bile duct. These patients underwent Roux-en-Y hepaticojejunostomy. Conclusion. Installation of drainage into the hepatic space and the right flank provide early diagnosis of postoperative complications, one of which is bile flow syndrome. Ultrasound examination of abdominal organs and endoscopic retrograde cholangiopancretography are performed to determine the cause and localization of the syndrome of the BL syndrome, depending on the volume of the BL. Repeated laparoscopy is indicated for the phenomena of bile peritonitis, significant accumulation of bile in the abdominal cavity. The complex usage of relaparoscopy, transduodenal endoscopic interventions and puncture techniques can significantly reduce the number of laparotomy operations to correct complications.

scholarly journals A CLINICAL CASE OF SURGICAL TREATMENT OF PEPTIC ULCER OF GASTROENTEROANASTOMOSIS

2021 ◽  
Vol 9 (1) ◽  
pp. 101-106
Author(s):  
S.V. Leonchenko ◽  
◽  
V.N. Petyushkin ◽  
A.P. Motin ◽  
A.A. Dyomin ◽  
...  
Keyword(s):  
Peptic Ulcer ◽  
Surgical Treatment ◽  
Clinical Case ◽  
Abdominal Cavity ◽  
Decisive Role ◽  
Pain Syndrome ◽  
Gastric Surgery ◽  
Early Postoperative Period ◽  
Actual Problem ◽  
Long Time

In the article a clinical case of surgical treatment of peptic ulcer of gastroenteroanastomosis complicated with perforation and gastrointestinal bleeding, is described. The patient was observed with the diagnosis: cholelithiasis, chronic calculous cholecystitis, for which planned laparoscopic cholecystectomy with draining of the abdominal cavity was performed. According to the discharge record, the operation ran without peculiarities. Later the patient was rehospitalized with complaints of weakness, nausea, vomiting, pain in the upper parts of the abdomen; he was diagnosed with ulcer of gastroenteroanastomosis and continuing bleeding that were indications for the surgical intervention for life-saving indications. From the patient words, a part of the stomach was resected more than 20 years before for gastric ulcer. Until the latest time, the patient felt satisfactory, but within 6 months pain in the abdomen reappeared, however, on examination cholelithiasis was identified, and the pain syndrome was attributed to this pathology. Assumably, after the first operation performed in 1995, a complication developed in the early postoperative period in the form of obstruction of gastroenteroanastomosis (anastomositis?), and additional gastroenteroanastomosis was applied. Conclusion. Peptic ulcer of anastomosis is an actual problem of the gastric surgery which may not only appear long time after the operation, but may give the same complications as «essential» peptic ulcer, and really threaten the life of patients. It should be noted that in some cases the intraoperative picture, experience and sensations of a surgeon play a decisive role in the diagnosis of surgical pathology even if they differ from the data of additional methods of examination.

scholarly journals Aotric esophageal fistula: etiopathogenesis and diagnostics (review of literature)

2021 ◽  
Vol 179 (6) ◽  
pp. 89-93
Author(s):  
R. Sh. Muslimov ◽  
Sh. N. Danielyan ◽  
I. E. Popova ◽  
N. R. Chernaya
Keyword(s):  
Surgical Treatment ◽  
Clinical Manifestations ◽  
Diagnostic Methods ◽  
Malignant Neoplasms ◽  
Esophageal Fistula ◽  
Aortic Diseases ◽  
Intravenous Contrast ◽  
Surgical Interventions ◽  
Advantages And Disadvantages ◽  
Unified Protocol

Aortic esophageal fistula (AEF) is a rare but extremely life-threatening condition requiring immediate surgical treatment. The mortality rate among such patients may exceed 60 %, including after surgical treatment. Etiological and pathogenetic mechanisms of AEF are complex and various, but in most cases, they are associated with chronic aortic diseases. The second group of etiological factors of AEF includes trauma of esophagus wall by foreign bodies, malignant neoplasms of the esophagus or mediastinum. AEF may also occur as a result of surgical interventions on the aorta and esophagus. The difficulties of early diagnosis are primarily associated with non-specific clinical manifestations of AEF and the lack of unified protocol for the examination of patients with the first-time upper gastrointestinal tract bleeding. The described reasons in some cases can lead to an inaccurate diagnosis, which entails a loss of time. Among the instrumental diagnostic methods, the most informative is the combination of esophagogastroduodenoscopy and computed tomography of the chest with intravenous contrast enhancement. Each of these methods has its advantages and disadvantages, and allows to identify a number of direct and indirect signs of pathological communication between the aorta and the esophagus.

scholarly journals ENDOMETRIOSIS AS A GLOBAL MULTI-LEVEL PROBLEM: RETROSPECTIVE CHARACTERISTIC OF PATIENTS.

2020 ◽  
Vol 20 (2) ◽  
pp. 63-69
Author(s):  
Yu.A. Orlova ◽  
V.B. Martynenko
Keyword(s):  
Surgical Treatment ◽  
Clinical Symptoms ◽  
Late Onset ◽  
Pain Syndrome ◽  
Gastrointestinal Diseases ◽  
Diagnostic Methods ◽  
Reproductive Age ◽  
Comprehensive Treatment ◽  
Carbohydrate Antigen 125 ◽  
History Of

The article outlines the issue of endometrioid disease, known as a complex gynecological polyetiological pathology. The total coverage of this pathology among women is 10%, with its spread up to 70% among women of reproductive age. The diversity and severity of clinical symptoms worsen not only the physical condition of the woman, but emotional status as well. To date, complicacy in the diagnosis and treatment of the disease gives raise a number of challenges requiring solution. Thus, endometriosis is still remaining a promising area of study, The aim of this study was to characterize the features of the anamnesis and symptoms of women with endometriosis, to determine the diagnostic value of the examination methods, to evaluate the effectiveness of the treatment tactics of women with this pathology. We carried out a retrospective analysis of case histories of 61 women with endometriosis. The diagnosis was 100% histologically confirmed. The average age of the women studied was 30,44 ± 5,6 years. Body mass index was 23,04 ±3,87 kg / m2. 16 women (26.22%) were diagnosed as overweight; 1st degree obesity was found in 2 women (3,27%). The onset of menstruation averaged 13,04 ± 1.07 years. Late onset of menarche was found out in 2 women (3,21%). The duration of menstruation ranged from 4,67 ±1.44 to 5,37 ±1,29 days with 1 reported case of menstrual bleeding for more than 8 days. 55,7% of women reported excessive menstrual blood loss. The interval of the menstrual cycle ranged from 21 to 32 days, was regular and amounted to 27,6±2.31 days. 47,54% of women experienced pain during menstruation. The increasing intensity of the pain syndrome from the moment of diagnosis was noted by 14 women, that made up to 48,27% of cases among 29 women with endometriosis and painful menstruation. There were 22 cases of pregnancy; miscarriages were recorded in 2 women (9,09%). 20 women (32,7%) had infertility, and in all the cases infertility was primary. When assessing the position of the uterus in the pelvis, it was revealed that 7 women (11,47%) had a retrograde uterine location, namely in the retroflexio position. When assessing the somatic history of the women studied, we noted that insult of various organs and systems was revealed in 53 women (86,88%). Top list is occupied by the gastrointestinal diseases, 64,1% of 53 studied cases. In addition to the underlying disease, 24 women (39,34%) had a history of gynaecological pathology. Carbohydrate antigen 125 was determined in 73,77% of cases, but only in 25 of these women this level was higher than 35.0 U / ml. Its value was established only in 55,5% of women. The detection of human epididymal protein 4 was carried out in 17 women (27,86%). Among these women, only in 1 case the level of human epididymal protein 4 exceeded the age normal values and was at the level of 69,59 pmol / L. By ultrasound diagnostic method, endometriosis was established only in 58,3% of cases. One woman was diagnosis to have endometriosis during magnetic resonance imaging. Therapy of endometriosis is divided into conservative and surgical. Before surgical treatment, 31 women (50,81%) were chosen for conservative management tactics, resulted in no effect. During surgical treatment with laparoscopic access, visible endometrioid heterotopies were observed in 50 women (81,96%), and in 18,04% endometriosis was not endoscopically diagnosed, while histologically was confirmed in 100% of cases. It is noteworthy that 46 women (75,4%) had adhesions of the pelvic organs, but only 22 women (47,82%) had had any surgical abdominal interventions before. Thus, endometriosis is a disease, which can not be described from a single unified point of view regarding its etiological factors. Severe clinical symptoms, the inability to use only non-invasive diagnostic methods for diagnosis, and the lack of comprehensive treatment that would provide the absence of relapse after the course of treatment, persistently force researchers and clinicians to deepen their knowledge and continue searching for methods to solve the problems of early diagnosis, treatment and prevention of the disease.

scholarly journals Mini-invasive methods of treatment of liquid formations of parhychymatic ogrgans and abdominal cavity in planned and urgent abdominal surgery

2018 ◽  
Keyword(s):  
Surgical Treatment ◽  
Minimally Invasive ◽  
Clinical Laboratory ◽  
Abdominal Cavity ◽  
Social Indicators ◽  
Pancreatic Head ◽  
Retroperitoneal Space ◽  
Diagnostic Methods ◽  
Head Tumors ◽  
Minimally Invasive Methods

The problem of diagnosis and treating-tactical criteria for liquid formations of the abdominal cavity and retroperitoneal space of non-parasitic genesis remains unsolved. The purpose of this study is to improve the results of surgical treatment of patients with liquid formations of the parenchymal organs, abdominal cavity and retroperitoneal space through the complex use of minimally invasive diagnostic methods and surgical treatment. Clinical-physical, then clinical-laboratory methods of examination of patients were performed, during which liquid structures were suspected Comparing different methods of surgical treatment of non-parasitic liquid formations of parenchymal organs and the abdominal cavity, it was established that the use of minimally invasive methods allowed to improve the medical and social indicators in this group of patients significantly. The use of puncture drainage methods in combination with conservative therapy for the treatment of pancreatic pseudocyst is effective. This method is important for diagnosing and determining the connection of a cyst with a duct, as well as for differential diagnosis with tumors. In patients with pancreatic head tumors complicated by obstructive jaundice, decompression of the gall tree by means of percutaneous transhepatic microcholecystostomy for 7–15 days significantly improved and normalized the functional state of the liver, which allowed for the application of bilidigents anastomoses. The use of puncture drainage methods under the control of sonography in liver cysts leads to a positive result of the treatment of this pathology and the prevention of complications. When comparing various methods of surgical treatment of non-parasitic fluid formations of parenchymatous organs, the abdominal cavity, it was found that the use of minimally invasive methods has significantly improved medical and social indicators in this group of patients.

scholarly journals Neuropsychological features of patients of reproductive age diagnosed with breast cancer at the stage of surgical treatment using xenon-oxygen therapy

2021 ◽  
Vol 8 (3) ◽  
pp. 10-20
Author(s):  
D. A. Rozenko ◽  
A. I. Shikhlyarova ◽  
L. N. Vaschenko ◽  
N. N. Popova ◽  
Yu. Yu. Arapova ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Surgical Treatment ◽  
Postoperative Period ◽  
Oxygen Therapy ◽  
Early Postoperative Period ◽  
Reproductive Age ◽  
Control Group ◽  
Newly Diagnosed ◽  
Beta Rhythm ◽  
Psychophysiological State

Purpose of the study. To study functional changes in the neuropsychological status of reproductive age patients with newly diagnosed breast cancer and to assess the possibility of using xenon-oxygen therapy to correct disorders.Patients and methods. This study included 60 reproductive age patients with newly diagnosed breast cancer who were undergoing surgical treatment at the Department of Bone, Skin, Soft Tissue and Breast Tumors of the National Medical Research Centre for Oncology of the Ministry of Health of Russia from 2018 to 2020. The main group included 30 patients with breast cancer diagnosed at the surgical stage of combined treatment, who underwent a rehabilitation course of xenon-oxygen therapy in the early postoperative period. The control group was formed from patients with the same diagnosis, without the use of this therapy. The functional state of the central nervous system in all patients was assessed by the parameters of the electroencephalography (EEG) bioelectrical activity. For the final assessment of the physiological and psychological state of the patients, a standardized questionnaires of the quality of life – ESAS, MOS-SF‑36, were used. Statistical data processing was performed using the Statistica 10 software package. Results. During the study, statistically significant differences were found in the assessment of subjective indicators, so in the group of patients using xenon-oxygen therapy, there was an improvement in well-being by 2.6 times, a decrease in depression by 2.3 times, a decrease in symptoms of nausea by 3 times, anxiety 1.9 times (p < 0.05). Against the background of an improvement in the psychophysiological state, the EEG showed a significant increase in the power of slow delta and theta rhythms, an increase in the power of the alpha rhythm and a decrease in the power of the beta rhythm, while in the patients of the control group only a decrease in the power of the beta rhythm was noted.Conclusion. The early postoperative period in patients with newly diagnosed breast cancer is characterized by the formation of a depressive symptom complex. The use of a course of xenon-oxygen therapy contributes to the normalization of the subjective feeling of physical and psychological health, increasing vital and social activity. Changes in the indicators of brain bioelectric activity and an improvement in psychophysiological state occur against the background of changes in brain activity caused by the normalizing effect of xenon.

Sign in / Sign up

Export Citation Format

Share Document