scholarly journals Platelet-Derived Growth Factor (PDGF) Gene Delivery for Application in Periodontal Tissue Engineering

2001 ◽  
Vol 72 (6) ◽  
pp. 815-823 ◽  
Author(s):  
William V. Giannobile ◽  
Caroline S. Lee ◽  
Matthew P. Tomala ◽  
Kristina M. Tejeda ◽  
Zhimin Zhu
2009 ◽  
Vol 9 (4) ◽  
pp. 248-266 ◽  
Author(s):  
Fa-Ming Chen ◽  
Zhi-Wei Ma ◽  
Qin-Tao Wang ◽  
Zhi-Fen Wu

2016 ◽  
Vol 8 (1) ◽  
pp. 46-48

ABSTRACT An elaborate system of signaling molecules regulates the cellular and molecular events of periodontal healing, the primary strategy for which is functional periodontal compartment regeneration and replication of components of the natural cellular microenvironment by providing an artificial extracellular matrix and by delivering growth factors. A new, so-called gene delivery method works by converting cells into protein- producing factories, thereby bypassing the dilemma. Gene therapy can channel the cellular signals in a controlled and very systematic manner, to provide encoded proteins at every stage of tissue regeneration. The aim of this review is to highlight the applications of gene delivery and tissue engineering in periodontal regeneration. How to cite this article Lakhani N, Vandana KL. Gene Therapy in Periodontal Tissue Engineering. CODS J Dent 2016;8(1):46-48.


2003 ◽  
Vol 9 (4) ◽  
pp. 745-756 ◽  
Author(s):  
Orasa Anusaksathien ◽  
Sarah A. Webb ◽  
Qi-Ming Jin ◽  
William V. Giannobile

2011 ◽  
Vol 56 (12) ◽  
pp. 1476-1484 ◽  
Author(s):  
Fawad Javed ◽  
Mansour Al-Askar ◽  
Abdulaziz Al-Rasheed ◽  
Khalid Al-Hezaimi

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