Low Cost Negative Pressure Wound Healing Device System

Background: In search for a faster and effective method Negative pressure wound therapy (NPWT) also known as Vacuum assisted wound closure (VAC) has emerged to be a promising technology over the years. This study was carried out to determine the clinical efficacy and cost effectiveness of Vacuum assisted closure (VAC) therapy compared to conventional wound therapy.Methods: A prospective randomised study using VAC was performed on cases with chronic non healing wounds using a low cost negative pressure therapy unit. The negative pressure used in the vacuum assisted closure of the wounds was provided by the wall mounted centralised suction apparatus which provided a constant average pressure of 125 mm of Hg (range being 110-200 mm Hg).Results: The rate of wound healing which was exhibited by reduction in size of the wound by more than 1 cm at the end of the first 5 days was higher in the cases (82%) as compared to the control (18%) group. By end of 15 days size reduction of >3 cm was seen almost 85% of the patients treated with NPWT. The total cost incurred in the first group undergoing VAC for a period of 15 days per patient was Rs.750 ($11.16) as against the second group undergoing conventional wound dressing which was Rs.700 ($10.41) for the same period per patient. The cost- benefit analysis of the two groups statistically revealed a p value of <0.05 under 95% confidence limits, thus proving vacuum assisted closure, though slightly expensive than the conventional dressing, to be a better and cost effective modality, taking into consideration the faster wound healing rates.Conclusions: In this study NPWT appeared to exhibit better wound healing and is thus a promising alternative to the conventional management and has a potential to be replicable across many hospitals with financial constraints in the low and middle income countries.

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Using Negative Pressure Therapy Can Accelerate Wound Healing

Internal Medicine News ◽

10.1016/s1097-8690(05)71480-3 ◽

2005 ◽

Vol 38 (3) ◽

pp. 43

Author(s):

Kerri Wachter

Keyword(s):

Wound Healing ◽

Negative Pressure ◽

Negative Pressure Therapy ◽

Pressure Therapy ◽

Accelerate Wound Healing

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Experience of negative pressure wound therapy over sternal wound healing: A retrospective review

WCET Journal ◽

10.33235/wcet.39.2.9-18 ◽

2019 ◽

Vol 39 (2) ◽

pp. 9-18

Author(s):

Wai Sze Ho ◽

Wai Kuen Lee ◽

Ka Kay Chan ◽

Choi Ching Fong

Keyword(s):

Wound Healing ◽

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Assessment Tool ◽

Wound Care ◽

Wound Therapy ◽

Treatment Pathways ◽

Wound Assessment ◽

One Year

Objectives The aim of this study was to retrospectively review the effectiveness of negative pressure wound therapy (NPWT) in sternal wound healing with the use of the validated Bates-Jensen Wound Assessment Tool (BWAT), and explore the role of NPWT over sternal wounds and future treatment pathways. Methods Data was gathered from patients' medical records and the institution's database clinical management system. Seventeen subjects, who had undergone cardiothoracic surgeries and subsequently consulted the wound care team in one year were reviewed. Fourteen of them were included in the analysis. Healing improvement of each sternal wound under continuous NPWT and continuous conventional dressings was studied. In total, 23 continuous NPWT and 13 conventional dressing episodes were analysed with the BWAT. Results Among conventional dressing episodes, sternal wound improvement was 2.5–3% over 10 days to 3.5 weeks, whereas 4–5% sternal healing was achieved in 5 days to 2 weeks with sternal wire presence. Better healing at 11% in 1 week by conventional dressing was attained after sternal wire removal. In NPWT episodes, 8–29%, 13–24%, and 15–46% of healing was observed in 2 weeks, 3.5 to 5 weeks and 6 to 7 weeks, respectively. Only 39% wound healing was acquired at the 13th week of NPWT in one subject. With sternal wire present, 6%–29% wound healing progress was achieved by NPWT in 1–4 weeks, and 16–23% wound improvement in 2 to 4.5 weeks by NWPT after further surgical debridement. After sternal wire removal, 6–34% sternal wound healing occurred by continuous NPWT for 1–2 weeks, and maximum healing at 46% after 2.5 weeks of NPWT were observed. Conclusions Better wound healing was achieved in the NPWT group in comparison to conventional dressings alone. However, suboptimal sternal wound healing by NPWT alone was observed. Removal of sternal wire may improve the effectiveness of NPWT. Successful tertiary closure after NPWT among subjects supports the important bridging role of NPWT in sternal wound healing. Factors causing stagnant sternal wound healing by NPWT alone are discussed.

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The effects and use of negative pressure wound therapy – a set of case reports

Perspectives in Surgery ◽

10.33699/pis.2020.99.4.183-188 ◽

2020 ◽

Vol 99 (4) ◽

pp. 183-188

Keyword(s):

Wound Healing ◽

High Risk ◽

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Chronic Wounds ◽

Wide Spectrum ◽

Case Reports ◽

Modern Medicine ◽

Wound Therapy ◽

Basic Set

Modern medicine offers a wide spectrum of wound healing resources for acute or chronic wounds. Negative pressure wound therapy (NPWT) is a very effective method, allowing complicated defects and wounds to heal. The basic set is usually provided with various special accessories to facilitate the use and support safe application of NPWT to high-risk tissue. Selected case reports are presented herein to document the special use and combinations of materials in negative pressure wound therapy.

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The role of angiopoetic factors in wound healing among patients with diabetes treated with negative-pressure wound therapy

Leczenie Ran ◽

10.15374/lr2015015 ◽

2015 ◽

Vol 11 (4) ◽

pp. 171-178

Author(s):

Beata Mrozikiewicz-Rakowska ◽

Joanna Kania ◽

Ewelina Bucior ◽

Adriana Nowak ◽

Tomasz Grzela ◽

...

Keyword(s):

Wound Healing ◽

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Wound Therapy ◽

Patients With Diabetes

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22 Flow and Pressure Differential Results of a Novel Low-Cost Portable Negative Pressure Patient Enclosure For COVID-19

Annals of Emergency Medicine ◽

10.1016/j.annemergmed.2021.07.023 ◽

2021 ◽

Vol 78 (2) ◽

pp. S11

Author(s):

P. Moschella ◽

B. Roth ◽

A. LeMatty ◽

R. Falconer ◽

E.S. Mousavi ◽

...

Keyword(s):

Negative Pressure ◽

Low Cost ◽

Pressure Differential

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Negative Pressure Provides Simple and Stable Droplet Generation in a Flow-Focusing Microfluidic Device

Micromachines ◽

10.3390/mi12060662 ◽

2021 ◽

Vol 12 (6) ◽

pp. 662

Author(s):

Nikita A. Filatov ◽

Anatoly A. Evstrapov ◽

Anton S. Bukatin

Keyword(s):

Microfluidic Device ◽

Negative Pressure ◽

Low Cost ◽

Control Valve ◽

Droplet Microfluidics ◽

Droplet Generation ◽

Electric Signal ◽

Absolute Pressure ◽

Flow Focusing ◽

Wide Range

Droplet microfluidics is an extremely useful and powerful tool for industrial, environmental, and biotechnological applications, due to advantages such as the small volume of reagents required, ultrahigh-throughput, precise control, and independent manipulations of each droplet. For the generation of monodisperse water-in-oil droplets, usually T-junction and flow-focusing microfluidic devices connected to syringe pumps or pressure controllers are used. Here, we investigated droplet-generation regimes in a flow-focusing microfluidic device induced by the negative pressure in the outlet reservoir, generated by a low-cost mini diaphragm vacuum pump. During the study, we compared two ways of adjusting the negative pressure using a compact electro-pneumatic regulator and a manual airflow control valve. The results showed that both types of regulators are suitable for the stable generation of monodisperse droplets for at least 4 h, with variations in diameter less than 1 µm. Droplet diameters at high levels of negative pressure were mainly determined by the hydrodynamic resistances of the inlet microchannels, although the absolute pressure value defined the generation frequency; however, the electro-pneumatic regulator is preferable and convenient for the accurate control of the pressure by an external electric signal, providing more stable pressure, and a wide range of droplet diameters and generation frequencies. The method of droplet generation suggested here is a simple, stable, reliable, and portable way of high-throughput production of relatively large volumes of monodisperse emulsions for biomedical applications.

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Evidence in Practice of Tissue Healing with Latex Biomembrane: Integrative Review

Journal of Diabetes Research ◽

10.1155/2019/7457295 ◽

2019 ◽

Vol 2019 ◽

pp. 1-17 ◽

Cited By ~ 1

Author(s):

Suélia de Siqueira Rodrigues Fleury Rosa ◽

Mário Fabrício Fleury Rosa ◽

Marcos Augusto Moutinho Fonseca ◽

Glécia Virgolino da Silva Luz ◽

Carlos Federico Domínguez Avila ◽

...

Keyword(s):

Diabetes Mellitus ◽

Wound Healing ◽

Chronic Diseases ◽

Low Cost ◽

Rubber Tree ◽

Antimicrobial Effect ◽

Integrative Review ◽

Complication Rates ◽

Biocompatible Material ◽

Tissue Healing

Wound healing is a perfectly coordinated cascade of cellular, molecular, and biochemical events which interact in tissue reconstitution. Chronic diseases such as pressure ulcers (PU) and diabetes mellitus (DM) are considered risk factors for wound healing. Patients with such diseases often have higher sepsis, infection, and complication rates, since they have revascularization inhibition and low growth factor expression. Thus, latex biomembrane (LBM), a biocompatible material, derived from the latex of the rubber tree (Hevea brasiliensis) appears to create tendencies as an angiogenic-inducing tissue healing agent and as biomaterial, resulting from its structural qualities and its low cost when compared to conventional treatments. Therefore, this work aims at summarizing the results, experiments, and scientific findings that certify or recommend the use of LBM as a new technique to be applied effectively in the treatment of wounds. An integrative review was held in the BIREME, LILACS, Burns, MEDLINE, PubMed, and SciELO databases, from 2000 to 2016, using the following descriptors: “healing,” “diabetes mellitus,” “wounds,” and “latex membrane.” As a result, 600 experiments (out of 612) presented satisfactory results; however, 33% of the cases received explicit recommendations, 11% required more studies on the subjects, and 1% was denied. On the other hand, half of the studies did not expressly endorse its use, despite presenting satisfactory results. The LBM was characterized as a good therapeutic alternative in cases of wounds, including chronic diseases, such as diabetes mellitus and PU, due to its relevant potential for wound healing stimulation, acceleration of cell tissue mending and revascularization, or the reestablishment of angiogenic functions (creation of new blood vessels). The LBM was also confirmed to be safe as a biocompatible material whose structural qualities (elasticity, adaptability, impermeability, and possibility of suture), devoid of toxicity, allowed interaction between tissues and presented no hypersensitivity inducer and no antimicrobial effect.

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