A Study on Variation of Phytochemical Constituents with Altitude and In vitro antimicrobial potential of two species of Ajuga L.

2017 ◽  
Vol 04 (01) ◽  
pp. 19-30
Author(s):  
Shabana Gulzar
Keyword(s):  
Antimicrobial Potential ◽  
Phytochemical Constituents

Antimicrobial Potential of Benzamides and Derived Nanosystems for Controlling in vitro Biofilm Development on Medical Devices

2013 ◽  
Vol 17 (2) ◽  
pp. 162-175 ◽  
Author(s):  
Carmen Limban ◽  
Alexandru Mihai Grumezescu ◽  
Mariana Chirea ◽  
Lilia Matei ◽  
Mariana Carmen Chifiriuc
Keyword(s):  
Medical Devices ◽  
Antimicrobial Potential ◽  
Biofilm Development

Synthesis, Characterization, Antimicrobial and Antioxidant Potential of Diazenyl Chalcones

2018 ◽  
Vol 18 (10) ◽  
pp. 844-856 ◽  
Author(s):  
Harmeet Kaur ◽  
Balasubramanian Narasimhan
Keyword(s):  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Antioxidant Potential ◽  
Dilution Method ◽  
Dpph Assay ◽  
Antimicrobial Potential ◽  
Structural Conformation ◽  
Uv Visible ◽  
Tube Dilution Method

A series of diazenyl chalcones was prepared by base catalyzed Claisen-Schmidt condensation of synthesized hydroxy substituted acetophenone azo dye with various substituted aromatic/ heteroaromatic aldehydes. The structural conformation of synthesized chalcones was done by a number of physicochemical and spectral means like FTIR, UV-visible, mass, NMR spectroscopy and CHNS/O analysis. These diazenyl chalcones were assessed for their in vitro antimicrobial potential against several Gram-negative, Gram-positive bacterial and fungal strains by serial tube dilution method. The fluconazole and cefadroxil were used as standard drugs. The target compounds were also evaluated for their antioxidant potential by DPPH assay. (2E)-3-(2,4-Dichlorophenyl)-1-(4-((2,6- dihydroxyphenyl)diazenyl)phenyl)prop-2-en-1-one (C-7) had shown very good antimicrobial potential with MIC ranges from 3.79 to 15.76 μg/ml against most of the tested microorganisms. Most of the synthesized diazenyl chalcones were found to be active against B. subtilis. The (2E)-1-(5-((2-Chloro- 4-nitrophenyl)diazenyl)-2-hydroxyphenyl)-3-(2-hydroxynaphthalen-1-yl)prop-2-en-1-one (C-10) had shown high free radical-scavenging activity when compared with the ascorbic acid as the reference antioxidant.

In vitro evaluation of antimicrobial potential and ability of biofilm formation of autochthonousLactobacillusspp. andLactococcusspp. isolated from traditionally made cheese from Southeastern Serbia

2018 ◽  
Vol 42 (11) ◽  
pp. e13776 ◽  
Author(s):  
Mirjana Ž. Muruzović ◽  
Katarina G. Mladenović ◽  
Milan D. Djilas ◽  
Olgica D. Stefanović ◽  
Ljiljana R. Čomić
Keyword(s):  
Biofilm Formation ◽  
In Vitro Evaluation ◽  
Antimicrobial Potential ◽  
Southeastern Serbia

scholarly journals Antimicrobial potential of Cordia myxa fruit on pathogenic bacteria: A study “in vitro” laboratory conditions

2020 ◽  
Vol 17 (101) ◽  
pp. 71-80
Author(s):  
Ebrahimi Hemati ◽  
Hossein Jooyandeh ◽  
Behrooz Alizadeh behbahani ◽  
Mohammad Noshad ◽  
◽  
...  
Keyword(s):  
Pathogenic Bacteria ◽  
Laboratory Conditions ◽  
Antimicrobial Potential ◽  
Cordia Myxa

Phytochemical, In vitro Anti-inflammatory and Antimicrobial Potential of Hugonia mystax L.

2021 ◽  
pp. 169-173
Author(s):  
K.P. Jaiganesh ◽  
T.J. Jasna ◽  
A.C. Tangavelou
Keyword(s):  
Tamil Nadu ◽  
Diclofenac Sodium ◽  
Inflammatory Activity ◽  
Phytochemical Analysis ◽  
Membrane Stabilization ◽  
Traditional System ◽  
Antimicrobial Potential ◽  
Biochemical Compounds ◽  
Anti Inflammatory

Hugonia mystax L., (Linaceae), is commonly distributed in the thorny scrubs and tropical dry evergreen forests of Tamil Nadu, which has been valued for centuries in traditional system of medicine for the treatment of various ailments. In the present study was an attempt to investigate the phytochemical nature and anti-inflammatory, antimicrobial potential by adopting suitable methods. Phytochemical analysis of Hugonia mystax L., plant extracts revealed the presence of various biochemical compounds such as alkaloids, flavonoids, glycosides, triterpenoids and saponins etc. Since triterpenoids and flavonoids have remarkable anti-inflammatory activity, so our present work aims at evaluating in vitro anti inflammatory activity of Hugonia mystax L., by HRBC membrane stabilization method. The inhibition of hypotonicity induced HRBC membrane lysis was taken as a measure of the anti-inflammatory activity. The percentage of membrane stabilization for ethanolic extracts and Diclofenac sodium were done at different concentrations. The maximum membrane stabilization of Hugonia mystax L., extracts was found to be 94.97 % at a dose of 2000 μg/ml. Therefore, our studies support the isolation and the use of active constituents from Hugonia mystax L., in treating inflammations.

Antimicrobial Potential of Three Common Weeds of Kurukshetra: An in vitro Study

2015 ◽  
Vol 10 (6) ◽  
pp. 280-287 ◽  
Author(s):  
Chetan Sharma ◽  
Sahaj Kaur ◽  
Smita Chaudhry ◽  
Robina Aman
Keyword(s):  
In Vitro Study ◽  
Vitro Study ◽  
Antimicrobial Potential

Phytochemical constituents, antioxidant and antidiabetic activities of different extracts of the leaves, stem and root barks of Alstonia boonei: an in vitro and in silico study

2019 ◽  
Vol 166 (4) ◽  
pp. 444-456
Author(s):  
Olajumoke A. Oyebode ◽  
Ochuko L. Erukainure ◽  
Collins U. Ibeji ◽  
Neil A. Koorbanally ◽  
Md. Shahidul Islam
Keyword(s):  
In Silico ◽  
In Silico Study ◽  
Phytochemical Constituents

scholarly journals BIOLOGICAL EVALUATION, QSAR AND MOLECULAR MODELING STUDIES OF 2,4-DICHLOROBENZOIC ACID DERIVATIVES AS ANTIMICROBIAL AGENTS

2019 ◽  
pp. 98-105
Author(s):  
SAMRIDHI THAKRAL ◽  
VIKRAMJEET SINGH
Keyword(s):  
Molecular Modeling ◽  
Antimicrobial Agents ◽  
Structural Characteristics ◽  
Docking Simulation ◽  
Biological Evaluation ◽  
Dilution Method ◽  
Bacterial Strains ◽  
Qsar Studies ◽  
Antimicrobial Potential

Objective: The aim of this study was to evaluate 2,4-dichlorobenzoic acid derivatives as antimicrobial agents through in vitro, QSAR and molecular docking studies. Methods: The compounds were subjected to in vitro antimicrobial screening by test tube dilution method and the structural characteristics governing the antimicrobial potential were studied using QSAR methodology. These compounds were also screened for docking simulation to find out binding confirmation of reported compounds with PDB 1aj0 and 5fsa using AutoDock tools and discovery studio. Results: The antimicrobial evaluation data indicated that compounds 13 and 18 were found to be the most effective against all the bacterial strains and Aspergillus niger while compounds 1 and 14 exhibited more antifungal potential against Candida albicans. QSAR studies confirmed the role of molar refractivity and Balaban index (J) as controlling parameters for antimicrobial potential. Molecular modeling study revealed that compounds interact with the active site of PDB by hydrophobic, hydrogen bonding, and Van der Wall interactions. Conclusion: These test compounds were identified as potent candidates for the control of microbial strains tested, and structural relationship with activity may provide valuable information for further design and synthesis of compounds with antimicrobial potential.

Antimicrobial potential of irrigants based on essential oils of Cymbopogon martinii and Thymus zygis towards in vitro multispecies biofilm cultured in ex vivo root canals

2020 ◽  
Vol 117 ◽  
pp. 104842
Author(s):  
Jelena Marinković ◽  
Dragana Mitić Ćulafić ◽  
Biljana Nikolić ◽  
Stefana Đukanović ◽  
Tatjana Marković ◽  
...  
Keyword(s):  
Essential Oils ◽  
Ex Vivo ◽  
Root Canals ◽  
Antimicrobial Potential ◽  
Multispecies Biofilm ◽  
Thymus Zygis ◽  
Cymbopogon Martinii
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