A List of Highly Influential Journals

2021 ◽  
Vol 11 ◽  
Author(s):  
Editorial Office ROS

This Education & Resources web page provides a list, in alphabetical order, of highly influential journals (typically with an impact factor of 10 or above) where high profile research articles on ROS may be found. This, however, is not intended to be a complete list. LIST IN ALPHABETICAL ORDER American Journal of Gastroenterology American Journal of Human Genetics American Journal of Respiratory and Critical Care Medicine Annals of Internal Medicine Annals of Neurology Autophagy Blood Brain British Medical Journal Cancer Research Cell (and Molecular Cell, Cancer Cell, Cell Metabolism, Cell Stem Cell, Developmental Cell, Cell Host Microbe) Cell Research Chest Circulation Circulation Research Current Biology EMBO J (and EMBO Molecular Medicine) European Heart Journal European Journal of Heart Failure European Respiratory Journal Gastroenterology Genes and Development Genome Biology Genome Research Gut Hepatology Immunity JAMA (and JAMA Internal Medicine, JAMA Cardiology) Journal of Allergy and Clinical Immunology Journal of the American College of Cardiology (and JACC Cardiovascular Imaging, JACC Cardiovascular Interventions, JACC Heart Failure)    Journal of Cell Biology Journal of Clinical Investigation Journal of Experimental Medicine Journal of the American Chemical Society Journal of the National Cancer Institute Lancet (and Lancet Oncology, Lancet Neurology, Lancet Diabetes & Endocrinology) Microbiome Molecular Biology and Evolution Molecular Cancer Molecular Plant Nature (and Nature Genetics, Nature Medicine, Nature Methods, Nature Biotechnology, Nature Materials, Nature Nanotechnology, Nature Communications, Nature Structural & Molecular Biology, Nature Neuroscience, Nature Immunology, Nature Cell Biology, Nature Chemical Biology, Nature Microbiology, Nature Plants, Nature Chemical Biology) Neuron New England Journal of Medicine Nucleic Acids Research Plant Cell PLOS Medicine Proceedings of the National Academy of Sciences of the United States of America Science (and Science Signaling, Science Translational Medicine, Science Immunology)

Author(s):  
A. Hakam ◽  
J.T. Gau ◽  
M.L. Grove ◽  
B.A. Evans ◽  
M. Shuman ◽  
...  

Prostate adenocarcinoma is the most common malignant tumor of men in the United States and is the third leading cause of death in men. Despite attempts at early detection, there will be 244,000 new cases and 44,000 deaths from the disease in the United States in 1995. Therapeutic progress against this disease is hindered by an incomplete understanding of prostate epithelial cell biology, the availability of human tissues for in vitro experimentation, slow dissemination of information between prostate cancer research teams and the increasing pressure to “ stretch” research dollars at the same time staff reductions are occurring.To meet these challenges, we have used the correlative microscopy (CM) and client/server (C/S) computing to increase productivity while decreasing costs. Critical elements of our program are as follows:1) Establishing the Western Pennsylvania Genitourinary (GU) Tissue Bank which includes >100 prostates from patients with prostate adenocarcinoma as well as >20 normal prostates from transplant organ donors.


2013 ◽  
pp. 57-64
Author(s):  
P. Biagi

BACKGROUND The burden of heart failure (HF) is enormous and its prevalence increases sharply with age. It has been estimated that heart failure affects up to 3% of the general population and 10% of the elderly. It contributes to hospital admission for most of them, mainly elder adults (admitted in internal medicine units) with more than one comorbidity, cognitive disorders, impairment and so on. Despite the increasing prevalence of heart failure, its exact incidence and prevalence remain largely unknown and probably underestimated due to a lack of accurate epidemiological data and difficulties associated with comorbidities and correct diagnosis: over 40% of recurrent hospitalization causes, either cardiac or extracardiac, cannot be determined due to the lack of data. AIM OF THE STUDY The objective of this study estimated the prevalence and the primary care burden associated with comorbidities in internal medicine units. METHOD The design: a longitudinal multicentric observational study using spot analysis three data sheets were filled in during the hospital stay according to three crucial moments: enrolment (“the index day”), admission and discharge. Will be analyzed the following primary outcomes: total and cardiovascular mortality, intensive unit care admission, recurrent cardiovascular disorders, length of stay, hospital readmission, changes in activities of daily living, need for care. Second outcomes: clinical, therapeutic, instrumental and laboratory changes during the admission process. Deep analysis of the following comorbidities will be also taken into account: acute and chronic kidney failure, anaemia, chronic obstructive pulmonary disease, muscle loss, nutritional status, cirrhosis of the liver, neoplasms, blood cell disorders, chronic inflammatory diseases. Further evalutation items: cognitive impairment, self-sufficiency and perception of quality life.


2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 458.2-458
Author(s):  
G. Singh ◽  
M. Sehgal ◽  
A. Mithal

Background:Heart failure (HF) is the eighth leading cause of death in the US, with a 38% increase in the number of deaths due to HF from 2011 to 2017 (1). Gout and hyperuricemia have previously been recognized as significant risk factors for heart failure (2), but there is little nationwide data on the clinical and economic consequences of these comorbidities.Objectives:To study heart failure hospitalizations in patients with gout in the United States (US) and estimate their clinical and economic impact.Methods:The Nationwide Inpatient Sample (NIS) is a stratified random sample of all US community hospitals. It is the only US national hospital database with information on all patients, regardless of payer, including persons covered by Medicare, Medicaid, private insurance, and the uninsured. We examined all inpatient hospitalizations in the NIS in 2017, the most recent year of available data, with a primary or secondary diagnosis of gout and heart failure. Over 69,800 ICD 10 diagnoses were collapsed into a smaller number of clinically meaningful categories, consistent with the CDC Clinical Classification Software.Results:There were 35.8 million all-cause hospitalizations in patients in the US in 2017. Of these, 351,735 hospitalizations occurred for acute and/or chronic heart failure in patients with gout. These patients had a mean age of 73.3 years (95% confidence intervals 73.1 – 73.5 years) and were more likely to be male (63.4%). The average length of hospitalization was 6.1 days (95% confidence intervals 6.0 to 6.2 days) with a case fatality rate of 3.5% (95% confidence intervals 3.4% – 3.7%). The average cost of each hospitalization was $63,992 (95% confidence intervals $61,908 - $66,075), with a total annual national cost estimate of $22.8 billion (95% confidence intervals $21.7 billion - $24.0 billion).Conclusion:While gout and hyperuricemia have long been recognized as potential risk factors for heart failure, the aging of the US population is projected to significantly increase the burden of illness and costs of care of these comorbidities (1). This calls for an increased awareness and management of serious co-morbid conditions in patients with gout.References:[1]Sidney, S., Go, A. S., Jaffe, M. G., Solomon, M. D., Ambrosy, A. P., & Rana, J. S. (2019). Association Between Aging of the US Population and Heart Disease Mortality From 2011 to 2017. JAMA Cardiology. doi:10.1001/jamacardio.2019.4187[2]Krishnan E. Gout and the risk for incident heart failure and systolic dysfunction. BMJ Open 2012;2:e000282.doi:10.1136/bmjopen-2011-000282Disclosure of Interests: :Gurkirpal Singh Grant/research support from: Horizon Therapeutics, Maanek Sehgal: None declared, Alka Mithal: None declared


2021 ◽  
Author(s):  
Harry Singer ◽  
Terrance G Cooper

Abstract Micromanipulators, more than any other instrument, opened the early doors to developing the powerful genetics of yeast that underlies much of the molecular work today. The ability to separate the spores of a tetrad and analyze their phenotypes generated the genetic maps and biology upon which subsequent cloning, sequencing, cutting edge molecular and cell biology depended. This work describes the development of those micromanipulators from garage to barn to factory and the developer of the sophisticated instruments we use today. For more than 30 years Carl Singer and his family were staunch and generous supporters of the International Conferences on Yeast Genetics and Molecular Biology meetings both in Europe and America. Carl Singer's displays at meetings became a traditional fixture and engaged the appetites of many students and advanced researchers to employ a technique that many perceived as too complicated or difficult, but which he made simple and easy to learn. His experiences also document a sketch of the international yeast meetings, their venues and how they developed through the years.


2021 ◽  
Vol 77 (18) ◽  
pp. 540
Author(s):  
Ayman Elbadawi ◽  
Alexander Dang ◽  
Islam Elgendy ◽  
Ravi Thakker ◽  
Aiham Albaeni ◽  
...  

2021 ◽  
Vol 77 (18) ◽  
pp. 785
Author(s):  
Hyeon-Ju Ali ◽  
Javier Valero Elizondo ◽  
Stephen Yishu Wang ◽  
Arvind Bhimaraj ◽  
Safi Khan ◽  
...  

2021 ◽  
Vol 34 ◽  
pp. 100812
Author(s):  
Ali Raza Ghani ◽  
Mohsin Sheraz Mughal ◽  
Sundeep Kumar ◽  
Sara Aslam ◽  
Mahboob Alam ◽  
...  

2019 ◽  
Vol 28 (1) ◽  
pp. 3-13 ◽  
Author(s):  
J. F. Veenis ◽  
J. J. Brugts

AbstractExacerbations of chronic heart failure (HF) with the necessity for hospitalisation impact hospital resources significantly. Despite all of the achievements in medical management and non-pharmacological therapy that improve the outcome in HF, new strategies are needed to prevent HF-related hospitalisations by keeping stable HF patients out of the hospital and focusing resources on unstable HF patients. Remote monitoring of these patients could provide the physicians with an additional tool to intervene adequately and promptly. Results of telemonitoring to date are inconsistent, especially those of telemonitoring with traditional non-haemodynamic parameters. Recently, the CardioMEMS device (Abbott Inc., Atlanta, GA, USA), an implantable haemodynamic remote monitoring sensor, has shown promising results in preventing HF-related hospitalisations in chronic HF patients hospitalised in the previous year and in New York Heart Association functional class III in the United States. This review provides an overview of the available evidence on remote monitoring in chronic HF patients and future perspectives for the efficacy and cost-effectiveness of these strategies.


2019 ◽  
Vol 16 ◽  
pp. 101007
Author(s):  
Kristin Primm ◽  
Alva O. Ferdinand ◽  
Timothy Callaghan ◽  
Marvellous A. Akinlotan ◽  
Samuel D. Towne ◽  
...  

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