scholarly journals The Effects of Vitamin D Supplementation on Serum Levels of 25 (OH) D, Serum Calcium, and Bone Density in Adolescent: A Literature Review

2021 ◽  
Vol 5 (2) ◽  
pp. 180
Author(s):  
Nurnashriana Jufri ◽  
Nurmaladewi Nurmaladewi ◽  
Fifi Nirmala
Keyword(s):  
Vitamin D ◽  
Bone Density ◽  
Literature Review ◽  
Bone Mass ◽  
Serum Calcium ◽  
Biochemical Parameters ◽  
Linear Growth ◽  
Mass Density ◽  
Vitamin D Supplementation ◽  
Bone Mass Density

Latar Belakang: Stunting dan penurunan densitas tulang merupakan salah satu masalah gizi yang umum diderita oleh remaja. Hal ini terjadi akibat kurangnya asupan zat gizi yang adekuat terutama vitamin D yang berfungsi untuk pertumbuhan tulang dan mineralisasi jaringan. Jumlah yang terbatas dari makanan dan faktor pigmentasi kulit menjadi penyebab terjadinya defisiensi vitamin D sehingga dibutuhkan upaya suplementasi untuk memenuhi kebutuhan tersebut.Tujuan: Untuk menganalisis efek suplementasi vitamin D terhadap pertumbuhan linier remaja.Metode: Penelusuran artikel pada tinjauan pustaka ini dilakukan menggunakan mesin pencarian melalui Medline, PubMed, EBSCO, ELSEVIER, Cambridge Core, dan WILEY. Artikel memuat teks penuh, berbahasa inggris dan tahun terbit mulai dari 2010 hingga 2020. Kata kunci pencarian yang dimasukkan adalah vitamin D supplementation, adolescent or teenagers, linear growth, dan Bone Mass Density (BMD).Hasil: Hasil skrining menemukan 12 artikel yang memenuhi kriteria inklusi dan diklasifikasikan berdasarkan luaran penelitian yaitu kadar serum 25(OH)D merupakan parameter biokimia yang merupakan luaran yang terdapat pada 10 artikel penelitian. Parameter biokimia serum kalsium sebanyak 6 artikel, densitas tulang sebanyak 8 artikel, dan tinggi badan 2 artikel.Kesimpulan: Suplementasi vitamin D yang diberikan pada remaja yang sehat maupun tidak sehat terbukti meningkatkan kadar serum 25(OH)D.Kata kunci: Suplementasi vitamin D, serum 25(OH)D, densitas massa tulang, pertumbuhan linier remaja. ABSTRACT Background: Stunting and decreased bone density are some of the common nutritional problems that remain by adolescents. This occurs due to lack of adequate nutrition, especially vitamin D which functions for bone growth and tissue mineralization. A limited amount of food and skin pigmentation factors cause vitamin D deficiency so supplementation efforts are needed to meet those needs.Objective: To analyze the effect of vitamin D supplementation on the linear growth of adolescents.Method: Searching for articles in this literature review was done using a search engine through Medline, PubMed, EBSCO, ELSEVIER, Cambridge Core, and WILEY. The article contains the full text, English language, and year of publication from 2010 to 2020. The search keywords entered are vitamin D supplementation, adolescent or teenagers, linear growth, and Bone Mass Density (BMD).Results: The screening results found 12 articles that met the inclusion criteria and were classified based on research outcomes, namely serum 25 (OH) D levels were biochemical parameters which were the results contained in 10 research articles. Biochemical parameters of serum calcium were 6 articles, bone density were 8 articles, and height were 2 articles.Conclusion: Vitamin D supplementation given to healthy and unhealthy adolescents has been shown to increase serum 25 (OH) D levels.Keywords: Vitamin D supplementation, serum 25 (OH) D, bone mass density, adolescent linear growth. 

scholarly journals Pengaruh Latihan Resisten terhadap Kepadatan Tulang

2021 ◽  
Vol 9 (2) ◽  
Author(s):  
Audy K. Bella ◽  
Hedison Polii ◽  
Herlina I. S. Wungow
Keyword(s):  
Resistance Training ◽  
Bone Density ◽  
Literature Review ◽  
Bone Mass ◽  
Resistance Exercise ◽  
Mass Density ◽  
Anaerobic Exercise ◽  
Google Scholar ◽  
Bone Mass Density ◽  
Mineral Density

Abstract : Resistance or resistance training has been recommended as a widely used treatment strategy for dealing with bone loss. Types of exercise that can be done include walking, running, weights bearing, and swimming. According to WHO in 2018, more than 80% of the adult population worldwide has less physical activity. Studies show that resistant exercise can increase bone density. This literature review aims to determine the effect of resistance training on bone density. This study was in the form of a literature review with data searches using four databases, which are ClinicalKey, Pubmed, MedLine, and Google Scholar. Resistance exercise can increase bone density. There are two types of exercise, named aerobic and anaerobic exercises. Research has shown that anaerobic exercise is more effective in increasing bone mass density compared to aerobic exercise because anaerobic exercise provides a bigger mechanical load to the bones, which triggers the bones to regenerate. The conclusion is that resistance exercise can increase bone density.Keywords : Resistance exercise, bone density.  Abstrak : Latihan tahanan atau resisten telah direkomendasikan sebagai strategi pengobatan yang banyak digunakan untuk menghadapi hilangnya massa tulang. Jenis latihan yang bisa dilakukan antara lain jalan kaki, berlari, angkat beban, dan berenang. Menurut WHO pada tahun 2018, lebih dari 80% populasi orang dewasa di seluruh dunia memiliki aktivitas fisik yang kurang. Penelitian-penelitian membuktikan bahwa latihan resisten dapat meningkatkan kepadatan tulang. Tinjauan pustaka ini bertujuan untuk mengetahui pengaruh latihan resisten terhadap kepadatan tulang. Penelitian ini berbentuk literature review dengan pencarian data menggunakan empat database yaitu ClinicalKey, Pubmed, MedLine, dan Google Scholar. Kata kunci yang digunakan yaitu physical exercise ATAU resistance exercise ATAU resistance training ATAU effect of resistance exercise ATAU latihan tahanan ATAU latihan beban DAN bone mass ATAU bone mineral density. Latihan secara resisten dapat meningkatkan kepadatan tulang. Latihan dapat dilakukan dengan dua jenis, yaitu latihan aerobik dan anaerobik. Penelitian membuktikan bahwa latihan anaerobik lebih efektif dalam menungkatkan kepadatan massa tulang dibandingkan dengan latihan aerobik karena latihan anaerobik memberikan beban mekanik yang lebih besar untuk tulang sehingga memicu tulang untuk melakukan regenerasi.  Kesimpulannya adalah latihan resisten dapat meningkatkan kepadatan tulang.Kata Kunci : Latihan resisten, kepadatan tulang

scholarly journals Long-Term Effects of Laparoscopic Sleeve Gastrectomy and Roux-en-Y Gastric Bypass on Body Composition and Bone Mass Density

Obesity Facts ◽  
2020 ◽  
pp. 1-10
Author(s):  
Julian Bühler ◽  
Silvan Rast ◽  
Christoph Beglinger ◽  
Ralph Peterli ◽  
Thomas Peters ◽  
...  
Keyword(s):  
Vitamin D ◽  
Gastric Bypass ◽  
Body Composition ◽  
Sleeve Gastrectomy ◽  
Bone Mass ◽  
Laparoscopic Sleeve Gastrectomy ◽  
Mass Density ◽  
Bone Mass Density

<b><i>Background:</i></b> Currently, the two most common bariatric procedures are laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB). Long-term data comparing the two interventions in terms of their effect on body composition and bone mass density (BMD) are scarce. <b><i>Objective:</i></b> The aim of this study was to assess body composition and BMD at least 5 years after LSG and LRYGB. <b><i>Setting:</i></b> Department of Endocrinology and Nutrition, St. Claraspital Basel and St. Clara Research Ltd., Basel, Switzerland. <b><i>Methods:</i></b>Bariatric patients at least 5 years after surgery (LSG or LRYGB) were recruited, and body composition and BMD were measured by means of dual-energy X-ray absorptiometry. Data from body composition before surgery were included in the analysis. Blood samples were taken for determination of plasma calcium, parathyroid hormone, vitamin D<sub>3</sub>, alkaline phosphatase, and C-terminal telopeptide, and the individual risk for osteoporotic fracture assessed by the Fracture Risk Assessment Tool score was calculated. After surgery, all patients received multivitamins, vitamin D<sub>3</sub>, and zinc. In addition, LRYGB patients were prescribed calcium. <b><i>Results:</i></b> A total of 142 patients were included, 72 LSG and 70 LRYGB, before surgery: median body mass index 43.1, median age 45.5 years, 62.7% females. Follow-up after a median of 6.7 years. For LRYGB, the percentage total weight loss at follow-up was 26.3% and for LSG 24.1% (<i>p</i> = 0.243). LRYGB led to a slightly lower fat percentage in body composition. At follow-up, 45% of both groups had a T score at the femoral neck below –1, indicating osteopenia. No clinically relevant difference in BMD was found between the groups. <b><i>Conclusions:</i></b>At 6.7 years after surgery, no difference in body composition and BMD between LRYGB and LSG was found. Deficiencies and bone loss remain an issue after both interventions and should be monitored.

Polymorphisms of the vitamin D receptor and their effect on bone mass density in patients with normocalcemic hyperparathyroidism

Endocrine ◽  
2015 ◽  
Vol 50 (3) ◽  
pp. 816-818 ◽  
Author(s):  
Jose Luis Perez Castrillón ◽  
Gonzalo Díaz-Soto ◽  
Olatz Izaola Jauregui ◽  
Enrique Romero ◽  
Daniel de Luis Román
Keyword(s):  
Vitamin D ◽  
Bone Mass ◽  
Vitamin D Receptor ◽  
Mass Density ◽  
Bone Mass Density ◽  
Normocalcemic Hyperparathyroidism

scholarly journals Association of vitamin D deficiency and bone mass with liver and heart iron overload in transfusion dependent thalassemia

2020 ◽  
Vol 7 (7) ◽  
pp. 1544
Author(s):  
Anjali Verma ◽  
Alok Khanna ◽  
Babita Jangra ◽  
Sanjiv Nanda ◽  
Surender Verma
Keyword(s):  
Vitamin D ◽  
Bone Mass ◽  
Iron Overload ◽  
Vitamin D Deficiency ◽  
Mass Density ◽  
Iron Concentration ◽  
Bone Mass Density ◽  
Liver Iron ◽  
Vitamin D Levels ◽  
Liver Iron Overload

Background: Transfusion dependent thalassemia patients are reported to have Vitamin D insufficiency/deficiency in many countries. Vitamin D hydroxylation occurs in the liver; whether liver iron overload interferes with this step has not been addressed till date. This study helps to establish an association between liver iron concentration (LIC) and heart iron concentration (MIC) with vitamin D levels and Bone Mass Density in these patients.Methods: A cross sectional study was done by including transfusion dependent Thalassemia patients (TM) if they had an assessment of Liver and cardiac iron done by T2*MRI and bone mineral density by DEXA. Clinical data regarding age, gender, type of iron chelation therapy and laboratory data of S. ferritin and Vitamin D was collected. Data was assessed using appropriate statistical methods.Results: Among 40 TM patients were taken and mean age was 17.6 years. Vitamin D deficiency was identified in 26(65%). 20 out of them had an LIC>7mg/g DW and 6 had MIC>1.65mg/g DW. There was a significant association between LIC>7mg/g and vitamin D level<20 ng/ml and a significant inverse correlation between LIC and vitamin D, suggesting that liver iron overload may indeed affect vitamin D metabolism. Osteopenia was present in 32.5% and osteoporosis was present in 27.5 % of all TM patients. Reduced Bone Mass Density was also found to be linked with iron over load.Conclusions: Regular monitoring of vitamin D levels and supplementation is required in patients with severe liver and heart iron load. More studies are needed to confirm these results.

scholarly journals MON-337 Peripheral Neurological Complications in Pregnancy- Is Idiopathic Transient Osteoporosis of Pregnancy Concerning?

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Asma Khaled Aljaberi ◽  
Miklos Szolics
Keyword(s):  
Vitamin D ◽  
Bone Mass ◽  
Mass Density ◽  
Healthy Woman ◽  
Neurological Complications ◽  
Hip Pain ◽  
Bone Mass Density ◽  
Transient Osteoporosis ◽  
Dxa Scan ◽  
Hip Mri

Abstract Idiopathic transient osteoporosis of pregnancy (ITOP) is a rare and under-reported condition that has affected healthy pregnancies. ITOP usually presents in the final trimester of a normal pregnancy. Radiographic studies detect drastic loss of bone mass, elevated rates of turnover in the bone, and edema in the affected portion. We present a 26-year-old previously healthy woman, who was admitted at 39 weeks of gestation with severe left hip pain and inability to walk for one month.The pain was constant, progressive, involving left lower limb, and associated with numbness and weakness. Neurological exam revealed diminished power in the left hip (motor power was 2/5), and inability to stand and walk due to pain in the left hip. She was unable to stand by herself. Investigations revealed anemia, low vitamin B12, low vitamin D and magnesium. Bilateral hip MRI showed increased T2WI signal in the left femoral head consistent with idiopathic transient osteoporosis of the left hip (ITOP). DXA scan showed bone mass density (BMD) below expected for age.The patient had induced vaginal labor without complication. The left hip pain improved after delivery. She was treated conservatively with Calcium, Magnesium and vitamin D. The patient symptoms completely resolved in 3 months post-delivery. DXA scan and Hip MRI at 1 year interval showed normal BMD and complete resolution of previous bone marrow edema and changes seen in MRI hip. This case report serves to highlight the effect of pregnancy on bone mass during third trimester which may result in transient osteoporosis of pregnancy leading to weakness and gait disturbance. Clinical symptoms can be misdiagnosed as a peripheral neurological complications instead of bone metabolism changes of pregnancy.

Calcaneal Bone Mass Modification in Recreational Runners

2016 ◽  
Vol 106 (6) ◽  
pp. 381-386 ◽  
Author(s):  
Elena Escamilla-Martínez ◽  
Alfonso Martínez-Nova ◽  
Beatriz Gómez-Martín ◽  
Raquel Sánchez-Rodríguez ◽  
Lourdes María Fernández-Seguín ◽  
...  
Keyword(s):  
Bone Density ◽  
Bone Mass ◽  
Mass Density ◽  
Control Sample ◽  
Bone Mass Density ◽  
Running Shoes ◽  
Negative Effect ◽  
Trabecular Bone Mass ◽  
Recreational Runners ◽  
The Impact

Background: The calcaneus is the bone of the foot that first receives the impact of running, generating vibrations that might have a positive effect in modifying the trabecular bone mass. The objective of this study was to determine the variation in calcaneal bone density in runners during a 6-month training season, comparing it with a control sample. Methods: Bone density of the heel was measured in 33 male recreational runners by means of a contact ultrasonic bone analyzer. Measurements were made on three occasions during a training season: at the beginning, at 350 km, and at 700 km. All of the runners wore the same model of running shoes during this period. Measurements of bone density were also made in a control sample of 62 men who did not engage in physical exercise. Results: There was a significant decrease in mean calcaneal bone density over the course of the training season (from 86.1 dB/MHz to 83.2 dB/MHz; P = .006), but no significant differences with the control sample value (from 80.7 dB/MHz to 81.1 dB/MHz; P = .314). The runners' body composition changed during the study period, with lean mass increasing and fat mass decreasing. Conclusions: Distance running seems to have a negative effect on calcaneal bone mass density during the course of a 700-km training season.

Sign in / Sign up

Export Citation Format

Share Document