scholarly journals Analgesic effect of coconut shell (Cocos nucifera L) liquid smoke on mice

2012 ◽  
Vol 45 (3) ◽  
pp. 156 ◽  
Author(s):  
Meircurius Dwi C.S ◽  
Tantiana Tantiana ◽  
Ira Arundina
2019 ◽  
Vol 13 (02) ◽  
pp. 271-279 ◽  
Author(s):  
Meircurius Dwi Condro Surboyo ◽  
Ira Arundina ◽  
Retno Pudji Rahayu ◽  
Dieni Mansur ◽  
Taufan Bramantoro

Abstract Objective Distilled liquid smoke (DLS) is a result of coconut processing by-product that not only serves as a natural food preservative but also has a promising therapeutic effect. The healing potential of DLS derived from coconut (Cocos nucifera L) shell was investigated on a traumatic ulcer with the diabetic rat. Materials and Methods DLS was analyzed the component by gas chromatograph mass spectrometry. Diabetic condition was induced by alloxan in 55 male Wistar rats. Ten mm of traumatic ulcer was made along the labial fornix incisive inferior after the diabetic condition was confirmed. Then DLS coconut shell, benzydamine hydrochloride, and sterile distilled water were applied topically for 3, 5, and 7 days. The potential healing was evaluated based on the expression of nuclear factor kappa beta (NFκB) and tumor necrosis factor alpha (TNF-α) on macrophages using immunohistochemical staining and the amount of collagen using Masson Trichome staining. The difference between each group was analyzed using one-way analysis of variance. The least significant difference test is used to determine the significant difference (p < 0.05). Results The major compounds found were phenol (36.6%), 2-methoxyphenol (guaiacol) (25.2%), furfural (17.8%), and 4-ethyl-2-methoxyphenol (3.5%) with 28 other minor constituents. The lowest NFκB and TNF-α expression on macrophage was observed by topical application of DLS derived from coconut shell for 3, 5, and 7 days of treatment. The amount of collagen was increased and indicated by the highest result of DLS compared to others. Conclusion The DLS derived from coconut (Cocos nucifera L) shell was able to improve traumatic ulcer healing in a person with diabetes.


2021 ◽  
Vol 4 (2) ◽  
pp. 94
Author(s):  
Dini Indah Berlianti ◽  
Danti Nur Indiastuti ◽  
Gondo Mastutik ◽  
Shaohong Lai

Introduction: Pain signals tissue damage that is capable of reducing thequality of life. Non-Steroidal Anti-inflammatory Drugs (NSAIDs) are known as effective analgesic drugs which have various side effects, therefore natural minerals are used as an alternative medicine for pain and inflammation, one of which is known to be coconut water. Hence this research was conducted to find out the differences of the analgesic effect between young coconut water (Cocos nucifera L.) with non-selective and COX-2 selective NSAID on mice induced with pain from acetic acid 0.6% 1 ml/100gBW of mice.Methods: True experimental, conducted at the Pharmacology Laboratory in Faculty of Medicine of Airlangga University involving the sample of 48 mice (6 groups). The recorded data was tested using the oneway ANOVA methodology before then continued with the posthoc test of LSD.Results: The addition of young coconut water (Cocos nucifera L.) with the dosage of 3 ml/100gBW, 4 ml/100gBW, and 4.5 ml/100gBW of mice doesn't give any significant analgesic effect even though the analgesic protection percentage increases accordingly to its dosage (12.32%, 18.72%, 26.88%), but non-selective and COX-2 selective NSAID give significant analgesic effect (p<0.05) on mice induced with pain from acetic acid 0.6% 1 ml/100gBW of mice.Conclusion: There are differences in the analgesic effect of young coconut water (C. nucifera L.) with non-selective and COX-2 selective NSAID on mice induced with pain from acetic acid 0.6% 1 ml/100gBW of mice.


2015 ◽  
Vol 1 (2) ◽  
pp. 187
Author(s):  
Yefrida ◽  
Yani Kasuma Putri ◽  
Richi Silvianti ◽  
Novita Lucia ◽  
Refilda ◽  
...  

  ABSTRACT The waste of red cedar wood, coconut husk and coconut shell has not been well used. They had been used as traditional cooking fuel and also direct food smoking process by community, but they still had several disadvantages. Those could be treated by the simple processing, they can produce new high economics product. In this research, the use of waste red cedar wood, coconut husk and coconut shell as resources of liquid smoke by pyrolization followed by condensation has investigated. Liquid smoke is condensates of smoke which have experienced storage and screening to separate the tar and particulate matter.   Liquid smoke that was produced were different in color and smells, light brown and smells of smoke of red cedar wood burn, blackness of brown and smells like burning smoke of coconut husk and brown with smelled like the smoke of burned coconut shell. The pH of liquid smoke of red cedar wood was 3.34, liquid smoke of coconut husk is 3.48 and liquid smoke of coconut shell was 3.21, where its value was influenced by the component of acid which were the biggest component in coconut shell liquid smoke. The result of characterization using GC/MS indicated that there were 27 compounds and the main component of liquid smoke of red cedar wood is acetic acid (45.17%), 2-propanone (15.75%), 1-hidroxy-2-propanone (7.36%), furfural (5.50%) and phenol (4.17%), 27 compounds with the main component of liquid smoke of coconut husk is acetic acid (42.00 %), phenol (25.99%), 2-propanone (7.04%), furfural (4.06%) and guaiacol (3.32%), and 37 compounds with the main component of coconut shell liquid smoke are acetic acid (51.99%), phenol (19.90%), methyl acetate (5.37%), furfural (4.56%), hydroxyl acetone (2.90%), guaiacol (2.62%) and syringol (1.85%).  Keywords: waste red cedar wood, coconut husk, coconut shell, liquid smoke,  GC/MS


2021 ◽  
Vol 10 (4) ◽  
pp. 459-467
Author(s):  
Meircurius Dwi Condro Surboyo ◽  
Fatma Yasmin Mahdani ◽  
Nurina Febriyanti Ayuningtyas ◽  
Arvind Babu Rajendran Santosh ◽  
Diah Savitri Ernawati ◽  
...  

Introduction: Coconut shell liquid smoke (CS-LS) from Cocos nucifera L. has been traditionally used by Indonesians as a natural preservative. Besides that, liquid smoke is also used as a medicine to treat various types of wounds. During the storage, liquid smoke resulting from pyrolysis is still questionable in relation to the oxidation process and changes in its properties and potentials. We observed the physical characteristics, components, toxicity, anti-inflammatory, anti-nociceptive properties, and effect in oral ulcer healing of CS-LS. Methods: Acidity was analyzed using a digital pH meter, density test was analyzed using a pycnometer, and the components were determined using gas chromatography-mass spectrometry (GC-MS). Eight concentrations of CS-LS (1%, 2%, 4%, 6%, 8%, 10%, 12%, and 14%) were tested on baby hamster kidney (BHK21) for the extract toxicity, carrageenan-induced rat paw edema for its anti-inflammatory properties, hot-plate test for its anti-nociceptive, and traumatized labial fornix incisive inferior for its oral ulcer healing. Results: The acidity of CS-LS was 2.296 and the density was 1.0102 g/mL. The major components analyzed were phenol (32.75%), 2-methoxy-phenol (17.45%), and furfural (13.09%). The CS-LS 100% and CS-LS 8% were the optimum concentrations for maintaining the BHK21 and increasing the number of fibroblasts in oral ulcer healing. The CS-LS 100% showed potent anti-nociceptive ability compared to other concentrations (P = 0.001), but not for the anti-inflammation properties. Conclusion: CS-LS is a promising natural herb for oral medicine, especially oral ulcer medicine.


2018 ◽  
pp. 334-345
Author(s):  
Elias Ricardo D. Padilla ◽  
Gabriela B. Belini ◽  
Gabriela T. Nakashima ◽  
Walter R. Waldman ◽  
Fabio M. Yamaji

2021 ◽  
Vol 24 (1) ◽  
pp. 24
Author(s):  
TATTU M. R. R ◽  
S. A. LINDAWATI ◽  
I N. S. MIWADA

The study aims to identify characteristics of the yogurt being incubated in green coconut shell (Cocos nucifera L. var. viridis Hassk). It was conducted in March 2020 at the Laboratory of Animal Product Technology and Mic- robiology Faculty of Animal Science, Udayana University. This studies used a Complete Random Design (CDR) with three treatments and five replications. The three treatments were incubated in a jar container (control) (P0), incubated in green coconut shell nonflesh (P1) and incubated in green coconut shell with flesh (P2). The variables observed were lactoce level, fat level, protein level and pH value. The results of this study have shown that yogurt’s characteristic indicated lactose and protein levels was not significantly different (P>0,05) in all treatments, but P2 fat levels was higher significantly (P<0,05) different than P1 and P0. pH values was not significantly different (P>0,05) with P1 and significantly different (P<0,05) with P0. Conclusing in this study that the characteristics of yogurt incubated in green coconut shell getting good results at lactose level 2,32,42%; fat level 10,60-12,50%; pro- tein level 4,80-4,90%; and value pH 4,14-4,24%.


2016 ◽  
Vol 3 (1) ◽  
Author(s):  
Simone Lopes do Rêgo de Oliveira ◽  
Tatiane Cavalcante Maciel ◽  
Soraya de Oliveira Sancho ◽  
Sueli Rodrigues

2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Dewi Ermaya

Liquid smoke is the result of condensation or condensation from the steam resulting from pyrolysis (combustion). From ingredients that contain lotsof lignin, cellulose, hemicellulose and carbon compounds which can be used as preservatives. Sawdust and coconut shell are sawdust, which is waste from the remains of refining wood on furniture and market waste from coconuts which are taken from coconut milk and oil. Both contain cellulose, hemicellulose, and lignin, these ingredients can be made into liquid smoke. The purpose of this study was to utilize sawdust and shell waste as liquid smoke which could be applied to the pickling and clumping industry. Making liquid smoke is done using a pyrolysis device. The liquid smoke formed is filtered. Then the yield was calculated and analyzed the quality of the liquid smoke, namely specific gravity, pH, and color. The results showed that the yield of sawdust was higher than coconut shell, namely 45.09%. And the resulting color is better sawdust.


2021 ◽  
Vol 11 (1) ◽  
pp. 85-91
Author(s):  
Zulfaidah Gama ◽  
◽  
Rizky Purnama ◽  
Dewi Melani ◽  
◽  
...  

Rice bug (Leptocorisa oracorius F) is one of the most dangerous pests for paddy commodities (Oryza sativa) in the world. The use of liquid smoke was popular among local farmers to control rice bug. A coconut shell is the main source for making liquid smoke. This research aims to analyse rice bugs' mortality and antifeedant activity when dipped with coconut shell liquid smoke. The liquid smoke's effectiveness was measured by dipping paddy (5 grams in weight) that is previously soaked with coconut shell liquid for 20 seconds. The liquid smoke was prepared in various concentrations, ranging from 0% as a control; 0.50%; 0.75%; 1%; 1.25% and 1,50%. Observations were made at 24, 48, 72, 96, 120, 144 and 168 hours. Data analysis was performed by one-way ANOVA test, using SPSS program followed by a 0.05 Tukey test to determine the significance of the rice bug pest mortality. The study resulted that the mortality values from low concentrations to high concentrations were 40%, 46.67%, 60%, 70%, and 80% over seven days. The antifeedant percentage of liquid smoke increased from low concentrations to high concentrations respectively were 10.14%, 15.15%, 31.03%, 46.15%, and 68.88% during seven days. The concentration of liquid smoke that has the highest mortality was 1.50%. In conclusion, 1.50% of liquid smoke showed the highest percentage of mortality and antifeedant activity with 80% and 68.88%, respectively. In the future, it is hoped to develop this model for commercial consumption and reduce reliance on chemicals to control rice bugs. The use of pesticides can do more harm than good, especially to the environmental system


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