scholarly journals Study of Aerobic Bacterial Profile in Chronic Suppurative Otitis Media and their Antibiotic Susceptibility Pattern

Author(s):  
Elizabeth Antony Hg. Sreedhara ◽  
L. Gayathree
2015 ◽  
Vol 16 (2) ◽  
pp. 79-82
Author(s):  
Metri C Basavaraj ◽  
P Jyothi

Introduction: Chronic suppurative otitis media (CSOM) remains one of the most common childhood chronic infectious diseases worldwide. It is recognized as an important cause of preventable hearing loss in the developing world. The present study was carried out to determine the etiological agent of CSOM and their antibiotic susceptibility pattern at the teaching hospital in North Karnataka.Methods: Samples were collected from patients in accordance with standard protocols. Organisms were identified by conventional microbiological techniques. Antibiotic susceptibility of the isolates was done by disc diffusion method according Clinical Laboratory Standards Institute (CLSI) guidelines.Results: A total of 159 patients were included in the study, out of which 53.5 % were males. Majority of the patients (85/159) were in the age group of 1-20 years. Pseudomonas was the most common organism causing CSOM, closely followed by Staphylococcus aureus. Pseudomonas were more sensitive to piperacilln-tazobactam (91%), followed by amikacin (80%). Among Staphylococcal isolates sensitivity was more to linezolid (93%), closely followed by piperacilln -tazobactam (88%). 73% of the Gram negative bacilli were sensitive to amikacin and 67% to gentamicinConclusion: Due to the easy availability and widespread use of antibiotics the susceptibility pattern of the pathogenic microorganisms are changing, therefore it is imperative to know the local susceptibility pattern of the causative agents, to treat the infection effectively.J MEDICINE July 2015; 16 (2) : 79-82


Author(s):  
Basavaraj Hiremath ◽  
Subramanya B. T.

<p class="abstract"><strong>Background:</strong> Chronic suppurative otitis media (CSOM) is a disease of mucoperiosteal lining of the middle ear cleft. The poor compliance of patients to antibiotic treatment, Incomplete treatment, misuse/improper choice of antibiotics have resulted in changes in susceptibility to antibiotics and also development of resistant strains by microbes to commonly used antibiotics. This study aimed to identify the mycobacteriological profile and determine antibiotic susceptibility pattern in CSOM patients.</p><p class="abstract"><strong>Methods:</strong> This cross sectional study was conducted on 120 clinically diagnosed cases of CSOM attending otolaryngology department. Ear discharges obtained were processed for microbial culture (aerobic, anaerobic and fungi). Antimicrobial susceptibility testing was done by Kirby–Bauer disc diffusion method.  </p><p class="abstract"><strong>Results:</strong> Of total 120 cases, pathogens were isolated from 114 cases. The commonest aerobic organism isolated was <em>Pseudomonas aeruginosa</em> (34.5%) followed by <em>Staphylococcus aureus</em> (29.4%). <em>Staphylococcus aureus</em> showed maximum sensitivity to erythromycin (70%), followed by cotrimoxazole (62.5%) and ampicillin (55%). Maximum resistance was observed for ciprofloxacin (77.5%), followed by amoxiclave (55%). <em>Pseudomonas aeruginosa</em> showed maximum sensitivity to piperacillin (89.36%) followed by gentamicin (70.2%), amikacin (70.2%), moderate sensitivity to ceftazidime (51.06%); however resistance to carbpenicillin (60%). Ciprofloxacin which is the most prescribed topical antibiotic showing an increase in resistance to causative organisms of CSOM.</p><p class="abstract"><strong>Conclusions:</strong> Hence, it becomes essential to study each case of CSOM bacteriologically to formulate local antibiotic policy for appropriate use of antibiotics. This will certainly help in achieving a safe ear and to control the organisms developing resistance to prevalent antibiotics.</p>


Author(s):  
Sriram Govindaraj ◽  
Jinu Vadakkanethu Iype ◽  
Srinivasa V. ◽  
Jayendiran S.

<p class="abstract"><strong>Background:</strong> Chronic suppurative otitis media (CSOM) is one of the common infective conditions which can cause many complications if not treated properly. Improper use of antibiotic among the common population has led to many drug resistant organisms; therefore it is necessary to study the antimicrobial susceptibility pattern before treating the patient with CSOM. Aim of the study was to identify the bacterial isolates causing CSOM in tubo tympanic disease and to study their antimicrobial susceptibility pattern.</p><p class="abstract"><strong>Methods:</strong> The study was carried out in ENT department in Vinayaka Mission Medical College, Karaikal from July 2018 till December 2018 for six months. 60 patients of CSOM (TTD) with ear discharge attending the ENT Out Patient Department were included in the study. Swabs were collected for culture and sensitivity. Bacterial isolates were identified using standard methods and antibiotic susceptibility testing were done.  </p><p class="abstract"><strong>Results:</strong> Pseudomonas species was the most predominant organism, which was seen in 19 patients (38%) followed by <em>Escherichia coli</em> (22%), <em>Staphylococcus aureus</em> (18%), <em>Klebsiella species</em> (10%).</p><p class="abstract"><strong>Conclusions:</strong> A continuous and periodic evaluation of microbiological pattern and their antibiotic sensitivity pattern prevalent in local area, helps in prescribe proper antibiotics for successful treatment of CSOM and thus minimizing its complications and emergence of resistant strains.</p><p class="abstract"> </p>


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