scholarly journals Agroclimatic Impact on Gastrointestinal Infection: A Mathematical Model

Author(s):  
Goutam Ghosh ◽  
Subhasish Bandyopadhyay ◽  
Amit Chattopadhyay

Identifying the correct dosage and time are key factors to successful implementation of anthelmintic. Comparing differential evolution of infection between anthelmintic treated animals against untreated ones, we present a mathematical model that first calibrates data collected and analyzed over an extended period of 10 years (2011-2019), and then predicts the dynamical evolution of gastrointestinal parasites in livestock, focusing specifically on Stronglye \& Coccidia oocysts, the two prime negative contributors to cattle health, measured using the standard Eggs-Per-Gram (EPG) index. The model incorporates information about all three critical regimes of infection - low infection regime ($< 50$ EPG), medium infection regime ($50-100$ EPG) and high infection regime ($>100$ EPG), including fatally large doses of infection ($> 500$), and probabilistically estimates the variation in animal weight due to infection propagation. A key success of our model is its ability to accurately predict the appropriate anthelmintic treatment times for cattle from a numerical solution of the model presented. The generic model can be applied to other agroclimatic conditions and can serve as a major diagnostic tool for anthelmintic strategizing.

Materials ◽  
2021 ◽  
Vol 14 (3) ◽  
pp. 474
Author(s):  
Huaqiao Liu ◽  
Yiren Pan ◽  
Huiguang Bian ◽  
Chuansheng Wang

In this study, the two key factors affecting the thermal performance of the insert rubber and stress distribution on the tire sidewall were analyzed extensively through various performance tests and simulations to promote the development of run-flat tires. Four compounds and two structures of insert rubber were designed to investigate the effects of heat accumulation and stress distribution on durability testing at zero pressure. It was concluded that the rigidity and tensile strength of the compound were negatively correlated with temperature. The deformation was a key factor that affects energy loss, which could not be judged solely by the loss factor. The stress distribution, however, should be considered in order to avoid early damage of the tire caused by stress concentration. On the whole, the careful balance of mechanical strength, energy loss, and structural rigidity was the key to the optimal development of run-flat tires. More importantly, the successful implementation of the simulations in the study provided important and useful guidance for run-flat tire development.


2002 ◽  
Vol 21 (1) ◽  
pp. 139-151 ◽  
Author(s):  
Peter J. Vander Nat ◽  
William W. Keep

A specific form of direct selling, multilevel marketing (MLM), experienced significant international growth during the 1990s, facilitated in part by the development of the Internet. A corresponding increase in the investigation and prosecution of illegal pyramid schemes occurred during the same period. These parallel activities led to increased uncertainty among marketing managers who used or wished to use the MLM approach. The authors examine similarities between the multilevel approach to marketing and activities associated with illegal pyramid schemes. A mathematical model is used to differentiate between the two on the basis of previous pyramid scheme cases and current U.S. law. The results of the model suggest key factors that marketers interested in MLM will need to consider when developing this type of distribution channel.


2021 ◽  
pp. 107815522199284
Author(s):  
Ana C Riestra ◽  
Carmen López-Cabezas ◽  
Marion Jobard ◽  
Mertxe Campo ◽  
María J Tamés ◽  
...  

Introduction The aim of this study is to compare productivity of the KIRO Oncology compounding robot in three hospital pharmacy departments and identify the key factors to predict and optimize automatic compounding time. Methods The study was conducted in three hospitals. Each hospital compounding workload and workflow were analyzed. Data from the robotic compounding cycles from August 2017 to July 2018 were retrospectively obtained. Nine cycle specific parameters and five productivity indicators were analysed in each site. One-to-one differences between hospitals were evaluated. Next, a correlation analysis between cycle specific factors and productivity indicators was conducted; the factors presenting a highest correlation to automatic compounding time were used to develop a multiple regression model (afterwards validated) to predict the automatic compounding time. Results A total of 2795 cycles (16367 preparations) were analysed. Automatic compounding time showed a relevant positive correlation (ǀrs|>0.40) with the number of preparations, number of vials and total volume per cycle. Therefore, these cycle specific parameters were chosen as independent variables for the mathematical model. Considering cycles lasting 40 minutes or less, predictability of the model was high for all three hospitals (R2:0.81; 0.79; 0.72). Conclusion Workflow differences have a remarkable incidence in the global productivity of the automated process. Total volume dosed for all preparations in a cycle is one of the variables with greater influence in automatic compounding time. Algorithms to predict automatic compounding time can be useful to help users in order to plan the cycles launched in KIRO Oncology.


Author(s):  
Valery KURGANOV ◽  
Mikhail GRYAZNOV ◽  
Egor TIMOFEEV ◽  
Liliya POLYAKOVA

The results of this study on the loss of live poultry at various stages of delivery from the farm to the processing plant by road are given. A factor analysis of the reasons for the loss of livestock delivered from the farm to the processing plant was carried out. The dependencies of livestock losses on loading delays and the duration of the movement of the loaded poultry farm to the processing plant were established. Methodological recommendations for rationing the number of injuries observed during delivery were developed. The study of losses of live birds during delivery to the processing plant from the density of stocking in shipping boxes was carried out; the economic and mathematical model for optimizing the landing of live birds in shipping boxes was proposed. The calculation of the economic impact of the implementation of the results of the study is given.


1986 ◽  
Vol 40 (2) ◽  
pp. 455-488 ◽  
Author(s):  
Kazimierz Poznański

Postwar Poland has experienced relatively great economic instability and recurring political upheavals, at least by East European standards. Recent dramatic developments include a severe economic crisis following an extended period of spectacular growth. The collapse of the once popular leadership of Edward Gierek, the creation of the first independent trade unions under a communist regime, and the replacement of party with military rule bear witness to the severity of Poland's political disruptions. Have economic or political factors caused the economic crisis? Which are the critical factors? Escalating internal political tensions and enormous external political pressures have caused Poland's current economic collapse, preventing the successful implementation of adjustment policies. The underlying sources of these political forces–namely, worker disillusionment with communist practices and confrontational relations between the superpowers–have not eased to date; the current malaise is likely to continue for some time.


2019 ◽  
Vol 10 (3) ◽  
pp. 1081
Author(s):  
Rajab Abduallah Hokoma ◽  
Hala Mansour Amaigl

This paper investigates in detail the current status of the implementation levels of JIT key-factors and their sub-elements within the cement industry within Libya, and its implication for management within the said industry. A survey methodology has been applied in this detailed investigation using an intensive questionnaire and one-to-one interviews of the correspondent organizations. Based on the analysis of the survey findings, the results show that the implementation status of the JIT key-factors and their sub-elements are found to be in the modest levels across all the surveyed organisations, thereby indicating to opportunities for eliminating waste and improving the value chain. This paper has also pointed to crucial areas where the senior management body within this industry need to take immediate actions in order to achieve an effective and successful implementation of JIT systems. The paper also makes a contribution by providing an insight into what extent the JIT key-factors and their sub-elements are understood and implemented within the key Libyan manufacturing industry.


Author(s):  
Yingxu Wang ◽  
Jian Huang

Software patterns are recognized as an ideal documentation of expert knowledge in software design and development. However, its formal model and semantics have not been generalized and matured. The traditional UML specifications and related formalization efforts cannot capture the essence of generic patterns precisely, understandably, and essentially. A generic mathematical model of patterns is presented in this article using real-time process algebra (RTPA). The formal model of patterns are more readable and highly generic, which can be used as the meta model to denote any design patterns deductively, and can be translated into code in programming languages by supporting tools. This work reveals that a pattern is a highly complicated and dynamic structure for software design encapsulation, because of its complex and flexible internal associations between multiple abstract classes and instantiations. The generic model of patterns is not only applicable to existing patterns’ description and comprehension, but also useful for future patterns’ identification and formalization.


2018 ◽  
Vol 8 (3) ◽  
pp. 371.3-372
Author(s):  
S McIlfatrick ◽  
DHL Muldrew ◽  
E Carduff ◽  
M Clarke ◽  
J Coast ◽  
...  

IntroductionConstipation is one of the most common symptoms in patients in specialist palliative care (SPC) settings and can cause considerable physical psychological and social suffering for the patient and their family. Due to the high variability in constipation assessment and management in SPC settings questions exist around how to implement an educational program in practice to address this clinical gap.AimTo develop and test the feasibility and acceptability of a novel educational intervention for HCPs to manage constipation experienced by people in SPC settings.MethodUsing the MRC framework for complex interventions and guided by the consolidated framework for implementation research an online resource was developed considering the content context and processes for implementation.ResultsAssessment prevention and management were identified as the core aspects. Six sessions with theoretical content application to practice and reflection through interacting with colleagues were developed in line with the best available evidence. Incentives including an educational bursary and alignment with revalidation and support from senior management champions and the research team were identified as key elements needed successful implementation. Funding IT infrastructure and attitudes to the content have been flagged as potential barriers to success.ConclusionA six week blended program covering the key concepts for assessment and management of constipation in palliative care has been created. Content evidence from the literature and empirical data on the preferred structure and method of delivery as well as key considerations of the contextual factors have been identified as key factors for implementation.References. Craig P, et al.Developing and evaluating complex interventions: The new medical research council guidance. BMJ Clinical Research Ed2008;337(October):a1655. Available at: http://discovery.ucl.ac.uk/168426/. Damschroder LJ, et al. Fostering implementation of health services research findings into practice: A consolidated framework for advancing implementation science. Implementation Science2009;4(50).. Friedrichsen M, Erichsen E. The lived experience of constipation in cancer patients in palliative hospital-based home care. Int J Palliat Nurs [Internet] 2004;10(7):321–5. Available from: http://search.ebscohost.com/login.aspx?direct=true&profile=ehost&scope=site&authtype=crawler&jrnl?=13576321&AN=13991056&h=XKMF4r08srZuhDY0j7C95oLLyYKNHUcvoeEuhyXNnsIM2BI%2BEhmcY1pPP%2BN1pvrMzQ9Bn9b5j45X6WzyBRydEA%3D%3D&crl=c [Accessed: 2017 August 21]. Tvistholm N, Munch L, Danielsen AK. Constipation is casting a shadow over everyday life? A systematic review on older people’s experience of living with constipation [Internet]. Journal of Clinical Nursing2017;26:902–14. Available from: http://doi.wiley.com/10.1111/jocn.13422 [Accessed: 2017 August 21]


2013 ◽  
Vol 837 ◽  
pp. 624-627
Author(s):  
Claudia Paula Fuioagă (Băsu)

Change is a common place nowadays. The fulminant engineering, innovation and globalization era brought with it an avalanche of changes and multiple challenges that organizations must face. Despite the change theme has been thought out and researched by hundreds of specialists, the practice shows that organizations have yet difficulties in implementing the changes they need. This is the motive why managers must deal with the issue of organizational changes carefully and take into consideration all factors that contribute to successful implementation of projects and changes that may increase the performance of companies they belong. Purpose The aim of this article is modelling and analysis the key factors that influence the organizational changes implementation within the business processes. Research, methodology Based on the main concepts in literature, a new specific model centered on the key factors that influence the organizational changes implementation within business processes will be presented and analysed. Findings The results indicate the main factors that influence change implementation in business processes and show a number of solutions for increase the success rate of this challenge for all the leaders of organizations. Originality, value The article promote a specific model of key factors that influence the organizational changes implementation, based on a critical review of change management literature. Numerous authors suggest a lot of recommendations for using and combining the factors of changes implementation, so that the results of change efforts to be the expected ones, but it is up to the leaders how they manage to implement researchers solutions in their organizations. This article presents that specific ways for Romanian managers, fitting with Romanian business environment. Implications This work leads to a better understanding of the key factors of the organizational changes implementation. The managers will have new perspectives to approach this matter and new solutions, in order to improve the change processes required by business.


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