scholarly journals A Highly Transparent and Explainable Artificial Intelligence Tool for Chronic Wound Classification: XAI-CWC

Author(s):  
Salih Sarp ◽  
Murat Kuzlu ◽  
Emmanuel Wilson ◽  
Umit Cali ◽  
Ozgur Guler

Artificial Intelligence (AI) has seen increased application and widespread adoption over the past decade despite, at times, offering a limited understanding of its inner working. AI algorithms are, in large part, built on weights, and these weights are calculated as a result of large matrix multiplications. Computationally intensive processes are typically harder to interpret. Explainable Artificial Intelligence (XAI) aims to solve this black box approach through the use of various techniques and tools. In this study, XAI techniques are applied to chronic wound classification. The proposed model classifies chronic wounds through the use of transfer learning and fully connected layers. Classified chronic wound images serve as input to the XAI model for an explanation. Interpretable results can help shed new perspectives to clinicians during the diagnostic phase. The proposed method successfully provides chronic wound classification and its associated explanation. This hybrid approach is shown to aid with the interpretation and understanding of AI decision-making processes.

Electronics ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1406
Author(s):  
Salih Sarp ◽  
Murat Kuzlu ◽  
Emmanuel Wilson ◽  
Umit Cali ◽  
Ozgur Guler

Artificial Intelligence (AI) has been among the most emerging research and industrial application fields, especially in the healthcare domain, but operated as a black-box model with a limited understanding of its inner working over the past decades. AI algorithms are, in large part, built on weights calculated as a result of large matrix multiplications. It is typically hard to interpret and debug the computationally intensive processes. Explainable Artificial Intelligence (XAI) aims to solve black-box and hard-to-debug approaches through the use of various techniques and tools. In this study, XAI techniques are applied to chronic wound classification. The proposed model classifies chronic wounds through the use of transfer learning and fully connected layers. Classified chronic wound images serve as input to the XAI model for an explanation. Interpretable results can help shed new perspectives to clinicians during the diagnostic phase. The proposed method successfully provides chronic wound classification and its associated explanation to extract additional knowledge that can also be interpreted by non-data-science experts, such as medical scientists and physicians. This hybrid approach is shown to aid with the interpretation and understanding of AI decision-making processes.


2021 ◽  
Author(s):  
Nicolas Scharowski ◽  
Florian Brühlmann

In explainable artificial intelligence (XAI) research, explainability is widely regarded as crucial for user trust in artificial intelligence (AI). However, empirical investigations of this assumption are still lacking. There are several proposals as to how explainability might be achieved and it is an ongoing debate what ramifications explanations actually have on humans. In our work-in-progress we explored two posthoc explanation approaches presented in natural language as a means for explainable AI. We examined the effects of human-centered explanations on trust behavior in a financial decision-making experiment (N = 387), captured by weight of advice (WOA). Results showed that AI explanations lead to higher trust behavior if participants were advised to decrease an initial price estimate. However, explanations had no effect if the AI recommended to increase the initial price estimate. We argue that these differences in trust behavior may be caused by cognitive biases and heuristics that people retain in their decision-making processes involving AI. So far, XAI has primarily focused on biased data and prejudice due to incorrect assumptions in the machine learning process. The implications of potential biases and heuristics that humans exhibit when being presented an explanation by AI have received little attention in the current XAI debate. Both researchers and practitioners need to be aware of such human biases and heuristics in order to develop truly human-centered AI.


2020 ◽  
pp. 43-57
Author(s):  
Anna Tabuika

The article reflects the results of a retrospective non-comparative study, the objects of which were 34 outpatient comorbid patients (15 of which are over 60 years old) with chronic wounds of the lower limbs developed against the background of varicosity, post-thrombotic disease, chronic arterial insufficiency of the lower limbs, diabetes mellitus or their combination. Their local treatment was carried out using atraumatic ointment dressing «Branolind N» containing Peruvian balsam. There were 23 women (67.6 %) and 11 men (32.4 %). In microbiological study prior to the beginning of treatment in 31 patients the growth of a pathogen of wound infection was revealed; in 19 patients — Staphylococcus aureus in monoculture and in various associations, in 6 patients — Pseudomonas aeruginosa in monoculture, in other cases — other pathogens. In 3 patients the pathogen was not detected. The average wound size was 34 cm2 . The phase of the wound process was additionally confirmed by cytological studies. After treatment the average area of the wound defect decreased by 10 cm2 and made 24 cm2 on average. Full healing of the wound defect occurred in 11 patients, the others had granulation and active marginal epithelization. There was also a decrease in bacterial semination of wounds, a change in composition of infection agents to less aggressive monoflora, and cytologically — a decrease in signs of inflammation against the background of significant activation of reparative processes.


Fuels ◽  
2021 ◽  
Vol 2 (3) ◽  
pp. 286-303
Author(s):  
Vuong Van Pham ◽  
Ebrahim Fathi ◽  
Fatemeh Belyadi

The success of machine learning (ML) techniques implemented in different industries heavily rely on operator expertise and domain knowledge, which is used in manually choosing an algorithm and setting up the specific algorithm parameters for a problem. Due to the manual nature of model selection and parameter tuning, it is impossible to quantify or evaluate the quality of this manual process, which in turn limits the ability to perform comparison studies between different algorithms. In this study, we propose a new hybrid approach for developing machine learning workflows to help automated algorithm selection and hyperparameter optimization. The proposed approach provides a robust, reproducible, and unbiased workflow that can be quantified and validated using different scoring metrics. We have used the most common workflows implemented in the application of artificial intelligence (AI) and ML in engineering problems including grid/random search, Bayesian search and optimization, genetic programming, and compared that with our new hybrid approach that includes the integration of Tree-based Pipeline Optimization Tool (TPOT) and Bayesian optimization. The performance of each workflow is quantified using different scoring metrics such as Pearson correlation (i.e., R2 correlation) and Mean Square Error (i.e., MSE). For this purpose, actual field data obtained from 1567 gas wells in Marcellus Shale, with 121 features from reservoir, drilling, completion, stimulation, and operation is tested using different proposed workflows. A proposed new hybrid workflow is then used to evaluate the type well used for evaluation of Marcellus shale gas production. In conclusion, our automated hybrid approach showed significant improvement in comparison to other proposed workflows using both scoring matrices. The new hybrid approach provides a practical tool that supports the automated model and hyperparameter selection, which is tested using real field data that can be implemented in solving different engineering problems using artificial intelligence and machine learning. The new hybrid model is tested in a real field and compared with conventional type wells developed by field engineers. It is found that the type well of the field is very close to P50 predictions of the field, which shows great success in the completion design of the field performed by field engineers. It also shows that the field average production could have been improved by 8% if shorter cluster spacing and higher proppant loading per cluster were used during the frac jobs.


Author(s):  
zhen zou ◽  
Lihua Zhang ◽  
Minzhi Ouyang ◽  
Yufei Zhang ◽  
Huanxiang Wang ◽  
...  

Nano-antibacterial agents play a critical role in chronic wound management. However, an intelligent nanosystem that can provide both visual warning of infection and precise sterilization remains a hurdle. Herein, a...


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